Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65624 produtos de "Derivados de Quinazolina e Quinolina"
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Toltrazuril
CAS:Produto Controlado<p>Applications A triazinetrione anticoccidial. Coccidiostat.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Eberts, T., et al.: Clin. Chem., 25, 1440 (1979), Goodwin, M., et al.: Avian Dis., 29, 630 (1985), Sorensen, S., et al.: Clin. Chim. Acta, 264, 103 (1997), Conway, D., et al.: Poult. Sci., 280, 426 (2001),<br></p>Fórmula:C18H14F3N3O4SCor e Forma:Off WhitePeso molecular:425.382-((6-Chloropyridin-3-yl)methyl)isoindoline-1,3-dione
CAS:Pureza:95.0%Peso molecular:272.69000244140625(±)-Mianserin-d3 Hydrochloride (methyl-d3)
CAS:Produto Controlado<p>Applications (±)-Mianserin-d3 HCl (methyl-d3) (CAS# 1219804-97-3) is a useful isotopically labeled research compound.<br></p>Fórmula:C18D3H17N2·ClHCor e Forma:NeatPeso molecular:303.8442O3-Desethyl Apremilast
CAS:Produto ControladoFórmula:C20H20N2O7SCor e Forma:NeatPeso molecular:432.45Medetomidine
CAS:<p>Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.</p>Fórmula:C13H16N2Pureza:99.88%Cor e Forma:SolidPeso molecular:200.28Clozapine N-Oxide
CAS:Produto Controlado<p>Impurity CLOZAPINE N-OXIDE IMPURITY<br>Applications Clozapine N-Oxide is a 5-HT2 antagonist. It is a major metabolite of clozapine (C587500) that can be monitored by HPLC.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Baldessarini, E., et al.: Neuropsychopharmacol., 9, 117 (1993); Lin, G., et al.: J. Pharm. Sci, 83, 1412 (1994); Roth, B.L., et al.: J. Pharmacol. Exp. Ther., 268, 1403 (1994)<br></p>Fórmula:C18H19ClN4OCor e Forma:Light Yellow To YellowPeso molecular:342.82Desmethyl Doxylamine
CAS:<p>Impurity Doxylamine EP Impurity C<br>Applications Desmethyl Doxylamine is an impurity of Doxylamine (D562000), an H1 Histamine receptor antagonist used as a antihistaminic and sedative agent.<br>References Pande, S.S., et al.: Int. J. Pharmtech. Res., 3, 209 (2011); Tiford, C.H., et al.: J. Am. Chem. Soc., 70, 4001 (1948);<br></p>Fórmula:C16H20N2OCor e Forma:NeatPeso molecular:256.34Moclobemide
CAS:Produto Controlado<p>Applications A reversible monoamine oxidase inhibitor.<br>References Wiesel, F.A., et al.: Eur. J. Clin. Pharmacol., 28, 89 (1985), Burkard, W.P., et al.: J. Pharmacol. Exp. Ther., 248, 391 (1989)<br></p>Fórmula:C13H17ClN2O2Cor e Forma:WhitePeso molecular:268.74Levofloxacin Carboxylic Acid (Levofloxacin Difluoro Impurity)
CAS:Produto Controlado<p>Impurity Levofloxacin USP Related Compound B<br>Applications Levofloxacin intermediate.<br>References Liu, Bo; Y., et al.: Bioorg. Med. Chem., 13, 2451 (2005), Lalitha D., et al.: J. Pharm. Biomed. Anal., 50, 710 (2009),<br></p>Fórmula:C13H9F2NO4Cor e Forma:NeatPeso molecular:281.21Rotigotine
CAS:<p>Rotigotine (1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-) is an antiparkinson agent and dopamine receptor agonist.</p>Fórmula:C19H25NOSPureza:99.04% - 99.88%Cor e Forma:SolidPeso molecular:315.47Tazarotene-d8
CAS:Produto Controlado<p>Applications Labelled Tazarotene (T010050). An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Fórmula:C21H13D8NO2SCor e Forma:YellowPeso molecular:359.512-Methyl-6-trifluoromethyl-nicotinic acid methyl ester
CAS:Pureza:95.0%Cor e Forma:LiquidPeso molecular:219.162994384765624-Methyl Erlotinib Hydrochloride
CAS:Produto Controlado<p>Applications Erlotinib (E625000) derivative as internal standard for HPLC.<br></p>Fórmula:C23H25N3O4·ClHCor e Forma:NeatPeso molecular:443.9232Sulindac Sulfone Acyl-β-D-Glucuronide
CAS:Produto Controlado<p>Applications Sulindac Sulfone Acyl-β-D-Glucuronide is the major metabolite of the non-steroidal anti-inflammatory drug Sulindac (S699215) in plasma and urine.<br>References Hucker, H.B., et al.: Drug Metab. Dispos., 1, 721 (1973),<br></p>Fórmula:C26H25FO10SCor e Forma:NeatPeso molecular:548.53Afatinib
CAS:<p>Applications An aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.<br>References Nakao, K., et al.: Sci. Rep., 9, 18202 92019); Ebert, K, PLoS One, 14, 0223225 (2019)<br></p>Fórmula:C24H25ClFN5O3Cor e Forma:NeatPeso molecular:485.94N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
CAS:Pureza:97.0%Peso molecular:348.7200012207031Ref: 10-F987646
1gA consultar5gA consultar5mg80,00€10mg102,00€25mg211,00€50mg362,00€100mgA consultar250mgA consultar1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol
CAS:Produto Controlado<p>Applications 1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a degradation product of phenylephrine during the synthesis of the anti-cold medicine.<br>References Dousa, M. et al.: J. Pharm. Biomed. Anal., 55, 949 (2011);<br></p>Fórmula:C15H17NO4Cor e Forma:NeatPeso molecular:275.3(S)-2-Aminobutyramide Hydrochloride
CAS:Produto Controlado<p>Impurity Levetiracetam USP Related Compound B<br>Applications Levetiracetam USP Related Compound B<br></p>Fórmula:C4H10N2O·ClHCor e Forma:White To Off-WhitePeso molecular:138.605-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
CAS:Pureza:95.0%Peso molecular:367.3699951171875Ethyl 2-(2-(2-fluorophenoxy)acetamido)-4-methyl-5-(phenylcarbamoyl)thiophene-3-carboxylate
CAS:Pureza:98%Peso molecular:456.489990234375Zuclopenthixol
CAS:Produto ControladoFórmula:C22H25ClN2OSCor e Forma:White To Light YellowPeso molecular:400.964-phenyl-3-(2-thienyl)-1,2,4-triazoline-5-thione 98%
CAS:Pureza:98.0%Peso molecular:259.35000610351561-(3-Nitropyridin-2-yl)piperidine-4-carbonitrile
CAS:Fórmula:C11H12N4O2Pureza:95.0%Peso molecular:232.243(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
CAS:<p>Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists such as Ticagrelor (T437700)for the prevention of thrombosis.<br>References Springthorpe, B. et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007);<br></p>Fórmula:C9H9F2N·C8H8O3Cor e Forma:NeatPeso molecular:321.32N-Acetal Bromopride
CAS:Produto Controlado<p>Applications N-Acetal Bromopride is an impurity of bromopride, which is an antiemetic.<br>References Fontaine, J., et al.: Arch. Int. Pharmacodyn. Ther., 213, 322 (1975), Lucker, P.W., et al.: Arzneim.-Forsch., 33, 453 (1983)<br></p>Fórmula:C16H24BrN3O3Cor e Forma:Off-WhitePeso molecular:386.28seco Everolimus B (~90%)
CAS:Produto Controlado<p>Applications seco Everolimus B is a metabolite of Everolimus (E945400); an immunosuppressant macrolide and analog of the parent drug Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)<br></p>Fórmula:C53H85NO15Pureza:~90%Cor e Forma:NeatPeso molecular:976.245-Amino-1-(5-chloro-2-pyridinyl)-1H-pyrazole-4-carbonitrile
CAS:Fórmula:C9H6ClN5Pureza:95.0%Cor e Forma:SolidPeso molecular:219.63N-Desmethyl Clozapine
CAS:Produto Controlado<p>Applications N-Desmethyl Clozapine is a metabolite of Clozapine (C587500). N-Desmethyl Clozapine is a potent, allosteric agonist at human M1 receptors and is able to potentiate hippocampal NMDA receptor currents through M1 receptor activation.<br>References Sur, C., et al.: Proc. Nat. Acad. Sci. U. S. A., 100, 13674 (2003); Kuoppamaki, M. et al.: Eur. J. Pharm. Mol. Pharm. Sect., 245, 179 (1993); Olessen, O.V., et al.: J. Chromatog., 622, 39 (1993); Pirmohamed, M., et al.: J. Pharmacol. Exp. Ther., 272, 984 (1995)<br></p>Fórmula:C17H17ClN4Cor e Forma:Light YellowPeso molecular:312.80Dofetilide-d4
CAS:Produto Controlado<p>Applications Potassium channel blocker.<br>References Carmeliet, D., et al.: J. Pharmacol. Exp. Ther., 262, 809 (1992), Norgaard, B.L., et al.: Am. Heart J., 137, 1062 (1999), Torp-Pedersen, C., et al.: N. Engl. J. Med. 341, 857 (1999)<br></p>Fórmula:C19H23D4N3O5S2Cor e Forma:NeatPeso molecular:445.593-Methyl-7-propylxanthine
CAS:Produto ControladoFórmula:C9H12N4O2Cor e Forma:White To Light YellowPeso molecular:208.22N-Triphenylmethyl Irbesartan
CAS:Produto Controlado<p>Impurity Irbesartan N2-Trityl Impurity<br>Applications Irbesartan (I751000) derivative.<br></p>Fórmula:C44H42N6OCor e Forma:NeatPeso molecular:670.848-benzyl-4-(pyridine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:381.4320068359375Lisinopril (S,S,R)-Diketopiperazine (~90%)
CAS:<p>Impurity Lisinopril EP Impurity D<br>Stability Hygroscopic<br>Applications Lisinopril (S,S,R)-Diketopiperazine (Lisinopril EP Impurity D) is an impurity of Lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor (1).<br>References 1. Goa, K. et al.: Drugs. 1996 Oct;52(4):564-88.<br></p>Fórmula:C21H29N3O4Pureza:~90%Cor e Forma:White To Off-WhitePeso molecular:387.475-p-Tolyl-1H-pyrazole-3-carboxylic acid methyl ester
CAS:Pureza:95.0%Peso molecular:216.24000549316406cis-ent-Tadalafil
CAS:Produto Controlado<p>Impurity Tadalafil EP Impurity C<br>Applications The (6S)-cis-enantiomer of Tadalafil (T004500). Tadalafil Impurity (6S,12aR)<br>References Aldridge, J., et al.: Br. Med. J., 318, 669 (1999), Daugan, A., et al.: J. Med. Chem., 46, 4533 (2003), Vredenbregt, M., et al.: J. Pharm. Biomed. Anal., 40, 840 (2006),<br></p>Fórmula:C22H19N3O4Cor e Forma:White To Off-WhitePeso molecular:389.40Saccharin N-(2-Acetic Acid Isopropyl Ester)(Piroxicam Impurity F)
CAS:Produto Controlado<p>Impurity Piroxicam EP Impurity F<br>Applications Piroxicam impurity F.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Fórmula:C12H13NO5SCor e Forma:NeatPeso molecular:283.304-phenyl-2-hydrophthalazin-1-one, 98%
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:222.2469940185547N-Butyl-N-methylnitrosamine (1 mg/mL in Methanol)
CAS:Fórmula:C5H12N2OCor e Forma:Single SolutionPeso molecular:116.16Pyrazinamide
CAS:Produto Controlado<p>Applications Antibacterial (tuberculostatic).<br>References Weiner, I.M., et al.: J. Pharmacol. Exp. Ther., 180, 411 (1972), Feldner, E., et al.: Anal. Profiles Drug Subs., 12, 433 (1983)<br></p>Fórmula:C5H5N3OCor e Forma:White To Off-WhitePeso molecular:123.111,1'-[(5E)-5-Methyl-7-oxo-5-undecene-1,11-diyl] Bis[Theobromine]
CAS:Fórmula:C26H34N8O5Cor e Forma:NeatPeso molecular:538.602-(2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:293.3219909667969Famotidine Acid Methyl Ester Hydrochloride (Famotidine Impurity)
CAS:Produto Controlado<p>Applications Famotidine acid methyl ester hydrochloride salt is a Famotidine (F102250) impurity.<br>References Junnarkar, G., et al.: Pharm. Res., 12, 599 (1995), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),<br></p>Fórmula:C9H14N4O2S2·ClHCor e Forma:NeatPeso molecular:310.824-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
CAS:Pureza:97.0%Peso molecular:361.7600097656252-Pyridin-3-yl-benzofuran-5-carboxylic acid methyl ester
Pureza:95.0%Peso molecular:253.2570037841797(aR)-3-Hydroxy-a-[[methyl(phenylmethyl)amino]methyl]-benzenemethanol
CAS:<p>Impurity Phenylephrine USP Related Compound D<br>Applications (αR)-3-Hydroxy-α-[[methyl(phenylmethyl)amino]methyl]-benzenemethanol (Phenylephrine USP Related Compound D) is a derivative of (R)-Phenylephrine (P320640, HCl salt) which is an α-Adrenergic agonist.<br>References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 86, 284 (1946); Gaglia, C.A., et al.: Anal. Profiles Drug Subs., 3, 483 (1974)<br></p>Fórmula:C16H19NO2Cor e Forma:NeatPeso molecular:257.333-Cyclopropyl-1-phenyl-1H-pyrazol-5-amine
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:199.2570037841797Chlorambucil
CAS:Produto Controlado<p>Applications Chlorambucil is a alkylating agent that is used as an chemotherapy drug in the treatment of chronic lymphocytic leukemia. Chlorambucil is also used to treat non-Hodgkin's lymphoma (NHL) and Hodgkin's disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cogia, A., et al.: Leuk. Lymph., 53, 1961 (2012); Tonino, S.H., et al.: Leuk. Lymph., 53, 1785 (2012); Smolej, L., et al.: Curr. Pharma. Design., 18, 3399 (2012);<br></p>Fórmula:C14H19Cl2NO2Cor e Forma:White To Light BeigePeso molecular:304.21Empagliflozin α-Anomer
CAS:Produto ControladoFórmula:C23H27ClO7Cor e Forma:White To Off-WhitePeso molecular:450.909N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline
CAS:Produto Controlado<p>Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline, is a metabolite of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Fórmula:C17H26N2O4Cor e Forma:NeatPeso molecular:322.399(S)-Lisinopril-d5 Sodium
CAS:Produto ControladoFórmula:C21H26D5N3NaO5Cor e Forma:NeatPeso molecular:433.514-(4-ethoxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione
CAS:Pureza:97%Peso molecular:298.3599853515625(E)-2-Chloro-3-imino-N,N-dimethylprop-1-en-1-amine Hydrochloride
CAS:Produto Controlado<p>Applications (E)-2-chloro-3-imino-N,N-dimethylprop-1-en-1-amine Hydrochloride is an impurity of Etoricoxib (E934100), a selective cyclo-oxygenase-2 (COX-2) inhibitor that is used to improve the signs and symptoms of osteoarthritis and rheumatoid arthritis.<br>References Hunt, R., et al.: Am. J. Gastroenterol., 98, 1725 (2003); Schumacher Jr., H., et al.: Bmj, 324, 1488 (2002)<br></p>Fórmula:C5H9ClN2·HClCor e Forma:Light YellowPeso molecular:169.05(R)-6,7-Dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine
CAS:Pureza:98.0%Cor e Forma:Liquid, No data available.Peso molecular:448.5899963378906Dolutegravir intermediate-1
CAS:Produto ControladoFórmula:C13H17NO8Cor e Forma:Light YellowPeso molecular:315.284-((3-Chloro-2,4-difluorophenyl)amino)-7-methoxyquinazolin-6-ol
CAS:Pureza:97.0%Peso molecular:337.70999145507812-(2-Aminoethoxy)anisole
CAS:Produto Controlado<p>Applications 2-(2-Aminoethoxy)anisole is used as an additive to vinylphosphonic acid esters and acrylonitrile forming compounds displaying hypotensive activity. An impurity from the process of Carvedilol (C184625)<br>References Reznik, V. et al.: Russ. Chem. Bull., 48, 979, (1999); Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990), Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996),<br></p>Fórmula:C9H13NO2Cor e Forma:NeatPeso molecular:167.204'-Ethoxyacetophenone
CAS:<p>Applications 4'-Ethoxyacetophenone, is an acetophenone derivative that can be used as an antibacterial agent. It is a reagent for plymerization. It can also be used as a flavoring agent in fabricating cigarettes with flavored filter tips.<br>References Sivakumar, P., et al.: Chem. Bio. Drug Design, 72, 303 (2008); Mathis, D. E., Beitraege zur Tabakforschung Int., 12, 1 (1983);<br></p>Fórmula:C10H12O2Cor e Forma:White To Off-WhitePeso molecular:164.203-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoylpropanamide (Famotidine Metabolite)
CAS:Produto Controlado<p>Impurity Famotidine EP Impurity I<br>Stability Light Sensitive<br>Applications 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide (Famotidine EP Impurity I) is a metabolite of the drug Famotidine.<br></p>Fórmula:C8H14N6O4S3Cor e Forma:NeatPeso molecular:354.43Anastrozole Mono Acid
CAS:<p>Impurity Anastrozole Monoacid Impurity<br>Applications Anastrozole Mono Acid is an impurity of Anastrozole (A637435), an aromatase enzyme inhibitor and antineoplastic agent. Anastrozole Monoacid Impurity<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Fórmula:C17H20N4O2Cor e Forma:Off-WhitePeso molecular:312.375,5-Diphenyl Hydantoin
CAS:<p>Applications Diphenyl Hydantoin is an anticonvulsant agent that suppresses abnormal brain activity associated with seizure. It is used to treat ulcers, epidermolysis bullosa, chorea, Parkinson’s syndrome, trigeminal neuralgia, acute alcoholism, and inflammatory conditions (1,2).<br>References (1) Kim, S. H., et al.: Birth Defects Res B Dev Reprod Toxicol. 95, 337 (2012)(2) Younes, N., et al.: Dermatol Online J. 12, 5 (2006)<br></p>Fórmula:C15H12N2O2Cor e Forma:WhitePeso molecular:252.27Terfenadine
CAS:Produto Controlado<p>Applications Nonsedating-type histamine H1-receptor antagonist. Antihistaminic.<br>References Carr, A.A., et al.: Arzneim. Forsch., 32, 1157 (1982), Badwan, A.A., et al.: Anal. Profiles Drug Subs., 19, 627 (1990), Masheter, H.C., et al.: Clin. Rev. Allergy, 11, 5 (1993), Jurima-Romet, M., et al.: Drug Metab. Dispos., 22, 849 (1994),<br></p>Fórmula:C32H41NO2Cor e Forma:White To Off-WhitePeso molecular:471.67(R)-Lercanidipine-d3 Hydrochloride
CAS:Produto ControladoFórmula:C36H39D3ClN3O6Cor e Forma:NeatPeso molecular:651.214-[6-(3-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Pureza:95.0%Peso molecular:278.31500244140625Riociguat-13C-d3
CAS:Produto Controlado<p>Applications Riociguat-13C-d3 is the labelled analogue of Riociguat (R520000), which is used in the treatment for pulmonary hypertension.<br>References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Fórmula:C1913CH16D3FN8O2Cor e Forma:NeatPeso molecular:426.43Loratadine-d4
CAS:Produto ControladoFórmula:C22H19D4ClN2O2Cor e Forma:Off White PowderPeso molecular:386.91Defluoro Paroxetine Hydrochloride
CAS:Produto ControladoFórmula:C19H22ClNO3Cor e Forma:NeatPeso molecular:347.84Loxoprofen-d3
CAS:Produto Controlado<p>Applications Loxoprofen-d3, is the labeled analogue of Loxoprofen (L472905), which is non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation.<br>References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);<br></p>Fórmula:C15H15D3O3Cor e Forma:NeatPeso molecular:249.32N-(3-Morpholinopropyl) Gefitinib
CAS:Produto Controlado<p>Applications N-(3-Morpholinopropyl) Gefitinib is a Gefitinib (G304000) impurity. It can also be synthesized from O-Desmorpholinopropyl Gefitinib (D296830).<br>References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001); Hirata, A., et al.: Cancer Res., 62, 2554 (2002); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003); Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005); Ranson, M., et al.: J. Clin. Oncology, 20, 2240 (2002); Mendelsohn, J., et al.: J. Clin. Oncology, 21, 2787 (2003); McKillop, D., et al.: Xenobiotica, 10, 917 (2004);<br></p>Fórmula:C29H37ClFN5O4Cor e Forma:NeatPeso molecular:574.0874-(4-Methoxyphenyl)thiophene-2-carboxylic acid
CAS:Fórmula:C12H10O3SPureza:95.0%Cor e Forma:SolidPeso molecular:234.272,5-Dioxopyrrolidin-1-yl 6-hydrazinylnicotinate hydrochloride
CAS:Pureza:98%Peso molecular:286.6700134277344Dihydroxy Bendamustine Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Dihydroxy Bendamustine is an impurity of Bendamustine (B132500).<br>References Watson, E., et al.: J. Pharm. Sci., 74, 1283 (1985), Teichert, J., et al.: Cancer Chemother. Pharmacol., 59, 759 (2007),<br></p>Fórmula:C16H22N3NaO4Cor e Forma:NeatPeso molecular:343.351-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:295.24200439453125Levosimendan
CAS:<p>Applications Bioactive enantiomer of racemate, Simendan. Positive inotropic agent with vasodilating activity. Cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995), Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996),<br></p>Fórmula:C14H12N6OCor e Forma:Yellow To Dark YellowPeso molecular:280.28Pyrimethamine-d3
CAS:Produto Controlado<p>Applications Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.<br>References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983), Leport, C., et al.: Am. J. Med., 84, 94 (1988), McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998), Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004),<br></p>Fórmula:C12H10D3ClN4Cor e Forma:Off-WhitePeso molecular:251.737-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
CAS:Pureza:98%Peso molecular:454.29901123046875Diethyl 2-Acetamido-2-[2-(4-octylphenylethyl)malonate
CAS:Produto Controlado<p>Applications An impurity found in fingolimod (F805000).<br></p>Fórmula:C25H39NO5Cor e Forma:NeatPeso molecular:433.58Tazarotenic Acid
CAS:Produto Controlado<p>Applications Tazarotenic acid is the major active metabolite of Tazarotene (T010050).<br>References Nagpal, S., et al.: J. Biol. Chem., 270, 923 (1995), Madhu, C., et al.: J. Pharm. Sci., 86, 972 (1997), Attar, M., et al.: Drug Metab. Dispos., 31, 476 (2003),<br></p>Fórmula:C19H17NO2SCor e Forma:NeatPeso molecular:323.41N-Phenoxycarbonylparoxetine
CAS:Produto Controlado<p>Applications N-Phenoxycarbonylparoxetine is an impurity of Paroxetine (P205750), a selective serotonin reuptake inhibitor. Used as an antidepressant.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),<br></p>Fórmula:C26H24FNO5Cor e Forma:NeatPeso molecular:449.47N-Boc-Sitagliptin
CAS:Produto Controlado<p>Applications N-Boc-Sitagliptin is the N-Boc protected derivative of Sitagliptin (S490990), a dipeptidyl peptidase-4 inhibitor that is used for glycemic control for patients with type 2 diabetes.<br>References Aschner, P., et al.: Diabetes Care, 29, 2632 (2006); Charbonnel, B., et al.: Diabetes Care, 29, 2638 (2006)<br></p>Fórmula:C21H23F6N5O3Cor e Forma:NeatPeso molecular:507.431-(6-Methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid
CAS:Pureza:95.0%Cor e Forma:Solid, No data available.Peso molecular:313.31298828125
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