Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65541 produtos de "Derivados de Quinazolina e Quinolina"
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Ethionamide
CAS:<p>Applications Antibacterial (tuberculostatic).<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>Fórmula:C8H10N2SCor e Forma:NeatPeso molecular:166.2411-Keto Oxcarbazepine
CAS:Produto Controlado<p>Stability Unstable in Solution<br>Applications A keto impurity of the anticonvulsant Oxcarbazepine (O869250).<br></p>Fórmula:C15H10N2O3Cor e Forma:NeatPeso molecular:266.253,4-Dehydro Cilostazol-d11
CAS:Produto Controlado<p>Applications A labelled metabolite of Cilostazol.<br></p>Fórmula:C20H14D11N5O2Cor e Forma:NeatPeso molecular:378.51Cilostazol-d11
CAS:Produto Controlado<p>Applications A potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.<br>References Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998), Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999), Tsuchikane, E., et al.: Circulation, 100, 21 (1999),<br></p>Fórmula:C20H16D11N5O2Cor e Forma:NeatPeso molecular:380.52Droperidol N-Oxide
CAS:Produto Controlado<p>Applications Droperidol N-Oxide is a derivative of Droperidol (D679500), a D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic.<br>References Yelnosky, J., et al.: Toxicol. Appl. Pharmacol., 6, 37 (1964), Janicki, C.A., et al.: Anal. Profiles Drug Subs., 7, 171 (1978), Hamik, et al.: Cancer Chemother. Pharmacol., 24, 307 (1989), Heyer, E.J., et al.: Brain Res., 863, 20 (2000),<br></p>Fórmula:C22H22FN3O3Cor e Forma:White To Off-WhitePeso molecular:395.437-Hydroxy Granisetron Hydrochloride
CAS:Produto Controlado<p>Applications Granisetron (G780000) metabolite.<br>References Bloomer, J., et al.: Brit. J. Clin. Pharmacol., 38, 557 (1994), Vernekar, S.,e t al.: J. Med. Chem., 53, 2324 (2010),<br></p>Fórmula:C18H24N4O2·ClHCor e Forma:NeatPeso molecular:364.87N-Nitrosoatrazine
CAS:Produto Controlado<p>Applications N-Nitrosoatrazine is an Atrazine (A794600) nitrosation product. Exposing human lymphocyte cultures to N-Nitrosoatrazine resulted in elevated levels of chromosome breakage.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Janzowski, C. et al.: ARC Sci. Pub., 31, 329 (1980); Meisner, L.F. et al.: Arch. Environ. Cont. Toxicol., 24, 108 (1993):<br></p>Fórmula:C8H13ClN6OCor e Forma:NeatPeso molecular:244.681,3,5-trimethyl-1H-pyrazole-4-carbonyl chloride
CAS:Fórmula:C7H9ClN2OPureza:95.0%Cor e Forma:SolidPeso molecular:172.61N-(R)-Glycidyl Phthalimide
CAS:Produto Controlado<p>Applications Reagent used for the simultaneous preparation of amino alcohol solvating agents as well as preparation of orally available anticoagulants.<br>References Roehrig, S. et al: J. Med. Chem., 48, 5900 (2005); Bozkurt, S. et al: Tetra: Asymm., 22, 541 (2011);<br></p>Fórmula:C11H9NO3Cor e Forma:NeatPeso molecular:203.19rac Rivastigmine-d6
CAS:Produto Controlado<p>Applications Labelled rac Rivastigmine. A brain selective acetylcholinesterase inhibitor. Nootropic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Fórmula:C14H16D6N2O2Cor e Forma:NeatPeso molecular:256.373-Vinylpyridine (>90%)
CAS:Produto ControladoFórmula:C7H7NPureza:>90%Cor e Forma:Light Yellow To Dark OrangePeso molecular:105.14rac-Methyl Ephedrine-d3 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled Ephedrine derivative for controlling respiratory tract goblet cell hyperplasia in respiratory diseases including infection and bronchitis.<br>References Tan, Z., et al.: J. Therm. Anal., 45, 59 (1995), van Berkel, G., et al.: Anal. Chem., 76, 479 (2004), Di, Y., et al.: Chin. Phy., 17, 3276 (2008),<br></p>Fórmula:C112H3H14NO·ClHCor e Forma:NeatPeso molecular:218.744-Hydroxy Omeprazole Preparation Kit
CAS:Produto ControladoFórmula:C16H17N3O3SCor e Forma:Off White SolidPeso molecular:331.396-Allyl-8b-carboxyergoline
CAS:<p>Impurity Cabergoline EP Impurity A<br>Applications 6-Allyl-8β-carboxyergoline is a metabolite of cabergoline (C050000) which is a dopamine D2-receptor agonist.<br>References Brambilla, E., et al.: Eur. J. Med. Chem., 24, 421 (1989), Ferrari, C., et al.: J. Clin. Endocrinol. Metab., 68, 1201 (1989), Hutton, J.T., et al.: Neurology, 46, 1062 (1996)<br></p>Fórmula:C18H20N2O2Cor e Forma:Light Beige SolidPeso molecular:296.3636Ticagrelor Epimer
Produto Controlado<p>Applications Ticagrelor Epimer is an epimer impurity of Ticagrelor (T437700). Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Fórmula:C23H28F2N6O4SCor e Forma:NeatPeso molecular:522.575-Aminoimidazole-4-carboxamide Lactose Adduct
Produto Controlado<p>Stability Hygroscopic<br>Applications 5-Aminoimidazole-4-carboxamide Lactose Adduct is a lactose adduct of 5-Aminoimidazole-4-carboxamide (A611690), a metabolite of Temozolomide (T017775).<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999)<br></p>Fórmula:C16H26N4O11Cor e Forma:NeatPeso molecular:450.45-chloro-4-methyl-N-(pyridin-4-ylmethyl)benzo[d]thiazol-2-amine
CAS:Pureza:95.0%Peso molecular:289.7799987792969LEE 011
CAS:Produto Controlado<p>Applications LEE 011 can be used in biological study of kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer.<br>References Jansen, V. M., et al.: Cancer Research, 77, 2488 (2017)<br></p>Fórmula:C23H30N8OCor e Forma:Light Yellow To BeigePeso molecular:434.54N-Methyl-N,N-bis(2-pyridylethyl)amine
CAS:<p>Impurity Betahistine EP Impurity C (Free Base)<br>Applications N-Methyl-N,N-bis(2-pyridylethyl)amine is used as a reagent in the preparation of copper pyridylmethylethylenediamine dicyanamido polymeric complexes.<br>References Mautner, F.A. et al.: Inorg. Chim. Acta, 362, 4073 (2009);<br></p>Fórmula:C15H19N3Cor e Forma:NeatPeso molecular:241.334'-Formylbiphenyl-2-carbonitrile
CAS:Produto Controlado<p>Applications 4'-Formylbiphenyl-2-carbonitrile is an impurity of Telmisartan (T017000), an angiotensin II receptor antagonist.<br>References Goossen, L.J., et al.: J. Org. Chem., 72, 7473 (2007);<br></p>Fórmula:C14H9NOCor e Forma:NeatPeso molecular:207.2274(R)-(+)-Bupivacaine Hydrochloride
CAS:<p>Applications (R)-(+)-Bupivacaine Hydrochloride is a local anaesthetic used for epidural and intrathecal anaesthesia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tullar, B., et al.: J. Med. Chem., 14, 891 (1971), Schmidt, A., et al.: Pharm. Res., 22, 2121 (2005),<br></p>Fórmula:C18H28N2O·HClCor e Forma:NeatPeso molecular:324.89S-(-)-Sulpiride-d3
CAS:Produto Controlado<p>Applications Labelled S-(-)-Sulpiride (S689140). Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.<br>References Pitre, D., et al.: Anal. Profiles Drug Subs., 17, 607 (1988), Wagstaff, A.J., et al.: CNS Drugs, 2, 313 (1994),<br></p>Fórmula:C152H3H20N3O4SCor e Forma:White To Light GreenPeso molecular:344.44O-Desmethyl Astemizole
CAS:Produto Controlado<p>Applications A metabolite of Astemizole.<br>References Nagata, K., et al.: J. Biol. Chem., 268, 24720 (1993), Benton, R., et al.: Clin. Pharmacol. Ther., 59, 383 (1996), Hashizume, T., et al.: Drug Metab. Dispos., 26, 566 (1998), Scarborough, P., et al.: Drug Metab. Rev., 31, 205 (1999),<br></p>Fórmula:C27H29FN4O·ClHCor e Forma:NeatPeso molecular:481.005-(Aminosulfonyl)-2-methoxy-benzoic Acid Methyl Ester
CAS:<p>Impurity Sulpiride EP impurity B<br>Applications A reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypoglycemic agents.<br></p>Fórmula:C9H11NO5SCor e Forma:White To Off-WhitePeso molecular:245.252-Methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS:Produto ControladoFórmula:C11H12F3NOCor e Forma:NeatPeso molecular:231.213’-Amino-2’-Hydroxy-[1,1’]biphenyl-3-carboxylic Acid
CAS:Produto Controlado<p>Applications 3’-Amino-2’-Hydroxy-[1,1’]Biphenyl-3-carboxylic Acid is used in the synthesis of monoethanolamine salts. A hydrazine cleavage product from Eltrombopag (E508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia<br>References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),<br></p>Fórmula:C13H11NO3Cor e Forma:NeatPeso molecular:229.231rac-Naproxen-13C,d3
CAS:Produto Controlado<p>Applications Labelled Naproxen. An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Fórmula:CC132H3H11O3Cor e Forma:NeatPeso molecular:234.272-Chloro Phenothiazine
CAS:Produto Controlado<p>Impurity Chlorpromazine EP Impurity E<br>Applications Metabolite of Chloropromazine<br>References Motohashi, N., et al.: Anticancer Res., 17, 4403 (1997), Azuine, M., et al.: Pharmacol. Res., 49, 161 (2004), Touil, F., et al.: J. Pharm. Biomed. Anal., 40, 822 (2006),<br></p>Fórmula:C12H8ClNSCor e Forma:GreyPeso molecular:233.72Ref: 10-F625925
1gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultar3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid
CAS:Pureza:98%Peso molecular:649.630004882813Ref: 10-F867169
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultar3’-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone(Domperidone Impurity E) (>90%)
CAS:Fórmula:C32H34ClN7O3Pureza:>90%Cor e Forma:White To Off-WhitePeso molecular:600.11Ethylenediamine P-Toluenesulfonate
CAS:Produto Controlado<p>Impurity Xylometazoline EP Impurity E<br>Stability Hygroscopic<br>Applications Ethylenediamine P-Toluenesulfonate is a reactant used in the synthesis of antitumor agents. Also is an impurity of Xylometazoline (X749950), a vasoconstrictor involved in signal transduction, also used as a nasal decongestant. May be used in treatments involving ischemic injury due to the ability to shift energy metabolism from mitochondrial to glycolysis (2).<br>References 1. Fliri, A. et al.: J. Med. Chem. 2009 Dec 24;52(24):8038-46.2. Gohil, V. et al.: Nat Biotechnol. 2010 Mar;28(3):249-55.<br></p>Fórmula:C7H8O3S·C2H8N2Cor e Forma:NeatPeso molecular:232.2999Menbutone
CAS:<p>Applications Menbutone is a cholerectic compound which is used for stimulating gastro-intestinal function by promoting secretory processes in animals including that of cattle, sheep, goats, horses and dogs. It is used in treatment of hepatic dysfunction of dogs by promoting bile secretion.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Symonds, H., et al.: Vet. Rec., 110, 423 (1982); Kumri, K., et al.: Indian Vet. J., 75, 1124 (1998);<br></p>Fórmula:C15H14O4Cor e Forma:Off White SolidPeso molecular:258.272(R,S)-Hydroxy-4[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]methylamino]-4-oxo-butanoic Acid
CAS:Produto ControladoFórmula:C13H17NO6Cor e Forma:NeatPeso molecular:283.284-Demethoxy-4-hydroxy Apixaban
CAS:Produto Controlado<p>Applications 4-Demethoxy-4-hydroxy Apixaban is a metabolite of Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Fórmula:C24H23N5O4Cor e Forma:NeatPeso molecular:445.47ABT 199 (>99%)(Venetoclax)
CAS:Produto Controlado<p>Applications ABT 199 (>99%) is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.<br>References Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013);<br></p>Fórmula:C45H50ClN7O7SCor e Forma:Light Yellow To YellowPeso molecular:868.44N-Nitroso Fluoxetine-D5
CAS:Produto ControladoFórmula:C17H12D5F3N2O2Cor e Forma:Colourless To Light YellowPeso molecular:343.36Fenoterol-d6 Hydrobromide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled Fenoterol (F248850). An β2-adrenergic agonist. Bronchodilator; tocolytic.<br>References Schuster, B., et al. Arzneim.-Forsch., 19, 1905 (1969), Gerris, J., et al.: Eur. J. Clin. Pharmacol., 18, 443 (1980), Heel, R.C., et al.: Drugs, 15, 3 (1978),<br></p>Fórmula:C17D6H15NO4·BrHCor e Forma:Off White To BrownPeso molecular:390.30(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran
CAS:Produto Controlado<p>Applications (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran is used as a reactant in the efficient synthesis of empagliflozin inhibitor of SGLT-2 utilizing AlCl3-promoted silane reduction of β-glycopyranoside.<br>References Wang, X., et al.: Org. Lett., 16, 4090 (2014);<br></p>Fórmula:C17H16BrClO2Cor e Forma:Off-WhitePeso molecular:367.66O-Desisopropyl-O-methoxyethyl Nimodipine
CAS:Produto Controlado<p>Impurity Nimodipine EP Impurity C; Nimodipine USP Related Compound B<br>Applications O-Desisopropyl-O-methoxyethyl Nimodipine (Nimodipine EP Impurity C) is an impurity in the synthesis of Nimodipine (A dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral). Nimodipine USP Related Compound B.<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Fórmula:C21H26N2O8Cor e Forma:NeatPeso molecular:434.44R-(-)-Deprenyl Hydrochloride
CAS:Produto Controlado<p>Applications Monoamine oxidase-B inhibitor related structurally to Pargyline. Used to alleviate the symptoms of Parkinsons disease.<br>References Magyar, K., et al.: Acta Physiol. Acad. Sci. Hung., 32, 377 (1967), Heinonen, E.H., et al.: Acta Neurol. Scand., 84, 44 (1991), Schneider, L.S., et al.: Am. J. Psychiatry, 150, 321 (1993),<br></p>Fórmula:C13H17N·ClHCor e Forma:White To Off-WhitePeso molecular:223.743-Hydroxy Ropivacaine
CAS:Produto Controlado<p>Applications A major metabolite of Ropivacaine (R675000).<br>References Ekstrom, G., et al.: Drug Metab. Dispos., 24, 955 (1996), Arvidsson, T., et al.: Biomed. Chromatogr., 13, 286 (1999), Shah, V., et al.: Pharm. Res., 17, 1551 (2000),<br></p>Fórmula:C17H26N2O2Cor e Forma:NeatPeso molecular:290.42,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]
CAS:Produto Controlado<p>Applications An impurity in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.<br>References Barve, I. et al.: Tetra., 69, 2834 (2013); Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995), Murata, S., et al.: J. Urol., 164, 578 (2000),<br></p>Fórmula:C25H30F3N3O3Cor e Forma:Light YellowPeso molecular:477.526-Hydroxy Ondansetron
CAS:<p>Applications A metabolite of Ondansetron.<br>References Colthup, P., et al.: J. Pharm. Sci., 80, 868 (1991), Miyauchi, S., et al.: Pharm. Res.,10, 434 (1993), Ekins, S., et al.: Drug Metab. Dispos., 23, 1274 (1995), Worboys, P., et al.: Xenobiotica, 26, 897 (1996),<br></p>Fórmula:C18H19N3O2Cor e Forma:Off-White To Light BrownPeso molecular:309.3623-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid
CAS:Produto Controlado<p>Impurity Bicalutamide EP Impurity M<br>Applications 3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid is an impurity of Bicalutamide (B382000); a non-steroidal peripherally active antiandrogen. Also used as an antineoplastic (hormonal).<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988); Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990); Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993); McKillop, D., et al.: Xenobiotica, 25, 623 (1995)<br></p>Fórmula:C10H11FO5SCor e Forma:NeatPeso molecular:262.25Deferiprone 3-O-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Deferiprone (D474000).<br>References Choudhury, R., et al.: Drug Metab. Dispos., 23, 314 (1995),<br></p>Fórmula:C13H16NNaO8Cor e Forma:Yellow To Dark YellowPeso molecular:337.26Naproxen-d3
CAS:Produto Controlado<p>Applications Naproxen-d3 is an isotopic compound of Naproxen (N377520). Naproxen is a a nonsteroidal anti-inflammatory compound with analgesic and antipyretic properties.<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Fórmula:C14H11D3O3Cor e Forma:Off-White To BeigePeso molecular:233.28Apixaban PG Ester-II
CAS:Produto Controlado<p>Applications Apixaban PG Ester-II is one of the multiple constituents extracted from Biebersteinia multifida, that exhibits inhibitory activity on acetylcholinesterase.<br>References Xiang, F., et al.: Faming Zhuanli Shenqing (2019), CN 109432093 A 20190308.<br></p>Fórmula:C28H30N4O6Cor e Forma:NeatPeso molecular:518.56Methyl 4-Acetamido-5-bromo-2-methoxybenzoate
CAS:Produto Controlado<p>Applications Methyl 4-Acetamido-5-bromo-2-methoxybenzoate is an impurity of bromopride (B686645), which is an antimetic.<br>References Fontaine, J., et al.: Arch. Int. Pharmacodyn. Ther., 213, 322 (1975), Lucker, P.W., et al.: Arzneim.-Forsch., 33, 453 (1983)<br></p>Fórmula:C11H12BrNO4Cor e Forma:Off-WhitePeso molecular:302.12Danofloxacin
CAS:<p>Applications Danofloxacin is a broad spectrum fluoroquinolone antibacterial compound.<br>References Golet, E., et al.: Anal. Chem., 73, 3632 (2001); Golet, E., et al.: Environ. Sci. Technol., 36, 3645 (2002); Huet, A., et al.: J. Agric. Food Chem., 54, 2822 (2006);<br></p>Fórmula:C19H20FN3O3Cor e Forma:Off-WhitePeso molecular:357.38Cimetidine Sulfoxide
CAS:Produto Controlado<p>Impurity Cimetidine EP Impurity E<br>Applications Cimetidine Sulfoxide (Cimetidine EP Impurity E) is a metabolite of the H2-receptor antagonist Cimetidine (C441650). Cimetidine Sulfoxide is detected in the blood and urine of patients with kidney diseases.<br>References Luksa, J. et al.: J. Chrom. B Biomed. Appl., 667, 321 (1995); Lee, R.M. et al.: J. Chrom. Biomed. Appl., 146, 354 (1978);<br></p>Fórmula:C10H16N6OSCor e Forma:NeatPeso molecular:268.344'-Methylbiphenyl-2-carbonitrile
CAS:Produto Controlado<p>Applications 4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.<br>References Lo Monte, F., et al.: J. Med. Chem., 55, 4407 (2012); Schaarschmidt, D., et al.: ACS. Catalysis., 1, 411 (2011);<br></p>Fórmula:C14H11NCor e Forma:NeatPeso molecular:193.24N-[2-[[[[1-Methyl-5-[(triphenylmethyl)amino]-1H-pyrazol-4-yl]amino]carbonyl]amino]ethyl]carbamic acid tert-butyl ester
CAS:Pureza:97%Peso molecular:540.6680297851562Ref: 10-F863727
1g16,00€5g45,00€10g87,00€1kg2.694,00€25g196,00€50g287,00€100g507,00€250g994,00€500g1.580,00€250mgA consultar5-Chloro-N-cyclohexylpentanamide
CAS:<p>Stability Hygroscopic<br>Applications 5-Chloro-N-cyclohexylpentanamide (cas# 15865-18-6) is a compound useful in organic synthesis.<br></p>Fórmula:C11H20ClNOCor e Forma:NeatPeso molecular:217.7364-Chloro-7-methoxy-2-phenylquinoline
CAS:Pureza:98.0%Cor e Forma:SolidPeso molecular:269.7300109863281Desfluoro Ezetimibe
CAS:Produto Controlado<p>Impurity Ezetimibe Desfluoroaniline Analog (USP)<br>Stability Hygroscopic<br>Applications An impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).<br>References Anon.: IP.com J., 7, 4 (2007);<br></p>Fórmula:C24H22FNO3Cor e Forma:White To Off-WhitePeso molecular:391.435,5',5''-(1,3,5-Triazine-2,4,6-triyl)tris(pyridin-2-amine)
CAS:Pureza:95%Cor e Forma:SolidPeso molecular:357.38101196289064-fluoro-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:259.299987792968754-(6-Fluoropyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile
CAS:Pureza:98%Peso molecular:326.33099365234375N,N'-Methylene Ambroxol Hydrochloride
CAS:Produto Controlado<p>Impurity Ambroxol EP Impurity B Hydrochloride<br>Stability Hygroscopic<br>Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).<br>References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);<br></p>Fórmula:C14H18Br2N2O·ClHCor e Forma:White To Off-WhitePeso molecular:426.571,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline
CAS:<p>Impurity Phenylephrine 4,6-DMTQ Impurity (Peak-2)<br>Applications Product formed during the decomposition of Phenylephrine<br>References Millard, B., et al.: J. Pharm. Pharmacol., 25, 24 (1973),<br></p>Fórmula:C10H13NO2Cor e Forma:Light YellowPeso molecular:215.68Ref: 10-F656645
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar2-[2-[[4-[(5S)-5-[[[(5-Chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-acetic Acid Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 2-[2-[[4-[(5S)-5-[[[(5-chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-acetic Acid Hydrochloride is a metabolite of Rivaroxaban (R538000) which is a novel antithrombotic agent. Rivaroxaban is also a highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005)<br></p>Fórmula:C19H20ClN3O6S·HClCor e Forma:White Light RedPeso molecular:453.903646(2E)-1-{[1,1'-biphenyl]-4-yl}-3-(5-methylthiophen-2-yl)prop-2-en-1-one
CAS:Pureza:95.0%Peso molecular:304.4100036621094((3S,4R)-4-(4-Fluorophenyl)piperidin-3-yl)methanol
CAS:Produto Controlado<p>Applications ((3s,4r)-4-(4-Fluorophenyl)Piperidin-3-Yl)Methanol (cas# 125224-43-3) is a useful research chemical.<br></p>Fórmula:C12H16FNOCor e Forma:Light YellowPeso molecular:209.266-ethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.36999511718752-Methyl-4-(morpholin-4-yl)aniline
CAS:Fórmula:C11H16N2OPureza:97%Cor e Forma:SolidPeso molecular:192.262N-Nitroso Desmethyl Olopatadine
Produto ControladoFórmula:C20H20N2O4Cor e Forma:NeatPeso molecular:352.384Carboxymefloquine-d3
CAS:Produto Controlado<p>Applications Labelled Carboxymefloquine (C178700). Carboxymefloquine is a metabolite of Mefloquine (M207050).<br>References Crevoisier, C., et al.: Eur. J. Clin. Pharmacol., 53, 135 (1997), Ridtitid, W., et al.: J. Pharm. Pharmacol., 52, 1265 (2000),<br></p>Fórmula:C12H2D3F6NO2Cor e Forma:NeatPeso molecular:312.181-(6,7-Dimethoxyphthalazin-1-yl)piperidin-4-yl ethylcarbamate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:360.414001464843752-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS:Produto Controlado<p>Applications 2-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a drug impurity of Lansoprazole, which is a proton pump inhibitor and used to treat stomach and intestinal ulcers.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000); Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001); Barradell, L.B., et al.: Drugs, 44, 225 (1992); Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002); Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006)<br></p>Fórmula:C14H12N4O3SCor e Forma:NeatPeso molecular:316.34Lercanidipine-d3
CAS:Produto Controlado<p>Applications Lercanidipine-d3 is a labeled dihydropyridine calcium channel blocker.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bianchi, G., et al.: Pharmacol. Res., 21, 193 (1989); Rimoldi, E., et al.: Acta Therap., 200, 23 (1994)<br></p>Fórmula:C36H38D3N3O6Cor e Forma:NeatPeso molecular:614.75Terfuboxon
CAS:Produto Controlado<p>Applications Terfuboxon is a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br>References Rahman, Md. M. et al.: Food CHem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008);<br></p>Fórmula:C9H21O3PS2Cor e Forma:NeatPeso molecular:272.363-methyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-5-amine
CAS:Pureza:95.0%Peso molecular:256.3299865722656Ondansetron-d3 Hydrochloride Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A labelled specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000),<br></p>Fórmula:C18H16D3N3O•HClCor e Forma:NeatPeso molecular:296.393646Deshydroxy Bicalutamide
CAS:Produto Controlado<p>Impurity Bicalutamide EP Impurity C<br>Applications Deshydroxy Bicalutamide (Bicalutamide EP Impurity C) is an impuirty of Bicalutamide. Bicalutamide intermediate.<br>References Lysiak, V., et al.: Bioorg. Med. Chem., 13, 671 (2005),<br></p>Fórmula:C18H14F4N2O3SCor e Forma:Off-WhitePeso molecular:414.37Regorafenib (Pyridine)-N-oxide
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Regorafenib (Pyridine)-N-oxide is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilhelm, S.: PCT Int. Appl. WO 2011130728 A1 20111020. Oct 20, 2011<br></p>Fórmula:C21H15ClF4N4O4Cor e Forma:NeatPeso molecular:498.81Dextrosimendan
CAS:Produto Controlado<p>Applications Dextrosimendan is an isomer and impurity of Levosimendan (L378000), a bioactive enantiomer of Simendan (S466000). Levosimendan is a positive inotropic agent with vasodilating activity.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)<br></p>Fórmula:C14H12N6OCor e Forma:Yellow To Dark YellowPeso molecular:280.281-(4-(Trifluoromethoxy)phenyl)-2-thiourea
CAS:Produto ControladoFórmula:C8H7F3N2OSCor e Forma:NeatPeso molecular:236.21Daprodustat
CAS:<p>Applications Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.<br>References Olson, E., et al.: Vasc. Med., 19, 473 (2014);<br></p>Fórmula:C19H27N3O6Cor e Forma:Off-WhitePeso molecular:393.43
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