Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65497 produtos de "Derivados de Quinazolina e Quinolina"
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5-CHLORO-N2-(4-FLUOROBENZYL)-N4-(5-ISOPROPOXY-1H-PYRAZOL-3-YL)PYRIMIDINE-2,4-DIAMINE
CAS:Pureza:95.0%Peso molecular:376.820007324218752-(5-Methyl-3-nitropyrazol-1-yl)ethanol
CAS:Fórmula:C6H9N3O3Pureza:95.0%Cor e Forma:SolidPeso molecular:171.1562-(5-Nitropyridin-2-yl)-1,2,3,4-tetrahydroisoquinoline
CAS:Pureza:97.0%Peso molecular:255.27699279785156Ref: 10-F511607
1gA consultar5gA consultar10gA consultar50mgA consultar100mgA consultar250mgA consultarETHYL 1-METHYL-3-(4-(TRIFLUOROMETHYL)PHENYL)-1H-PYRAZOLE-5-CARBOXYLATE
CAS:Pureza:97.0%Peso molecular:298.2650146484375O-Desmethyl Gefitinib
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A major metabolite of Gefitinib.<br>References Ranson, M., et al.: J. Clin. Oncology, 20, 2240 (2002), Mendelsohn, J., et al.: J. Clin. Oncology, 21, 2787 (2003), McKillop, D., et al.: Xenobiotica, 10, 917 (2004),<br></p>Fórmula:C21H22ClFN4O3Cor e Forma:YellowPeso molecular:432.888-methyl-4-(pyridine-4-carbonyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:304.34600830078125[3-(1H-Pyrazol-1-yl)phenyl]methylamine
CAS:Fórmula:C10H11N3Pureza:95%Cor e Forma:LiquidPeso molecular:173.2194-(3-methylthiophen-2-yl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:273.3699951171875Benzocaine-d4
CAS:Produto Controlado<p>Applications Labelled Benzocaine (B202970). Benzocaine is used as an anesthetic (local).<br>References Ali, S.L., et al.: Anal. Profiles Drug Subs., 12, 73 (1983),<br></p>Fórmula:C92H4H7NO2Cor e Forma:NeatPeso molecular:169.212,5-Bis(2-hexyldecyl)-3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
CAS:Pureza:99%Peso molecular:749.21002197265622-(4-(2-Hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:370.4049987792969Ref: 10-F238631
1gA consultar1mgA consultar5mgA consultar10mgA consultar100mgA consultar250mgA consultar4-Desmethyl-3-methyl Celecoxib
CAS:Produto Controlado<p>Impurity Celecoxib Related Compound A<br>Applications 4-Desmethyl-3-methyl Celecoxib is a meta positional isomer of Celecoxib (C251000) with selective inhibitory activity against human cyclooxygenase-2. USP Celecoxib Related Compound A<br>References Sreenivas, R.D. et al.: J. Pharmac. Biomed. Anal., 25, 21 (2001);<br></p>Fórmula:C17H14F3N3O2SCor e Forma:White To Light YellowPeso molecular:381.37Vildagliptin Racemic
CAS:<p>Applications Vildagliptin Racemic is an impurity of Vildagliptin (V305000),a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Fórmula:C17H25N3O2Cor e Forma:NeatPeso molecular:303.399Pomalidomide-(d4 major)
CAS:Produto Controlado<p>Applications Pomalidomide-d4 is the labeled anaxlogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.<br>References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)<br></p>Fórmula:C13H7D4N3O4Cor e Forma:NeatPeso molecular:277.276-nitro-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:286.309997558593751-Phenyl-3-thiophen-2-yl-1H-pyrazole-5-carboxylic acid
CAS:Cor e Forma:SolidPeso molecular:270.30999755859375Ref: 10-F212961
1g14,00€5g29,00€10gA consultar25g57,00€50gA consultar100gA consultar250gA consultar500gA consultar(S)-4-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one
CAS:Pureza:98.0%Peso molecular:479.172417372METHYL 6-(ETHYLAMINO)-2-FLUOROPYRIDINE-3-CARBOXYLATE
CAS:Pureza:95.0%Peso molecular:198.19700622558594(4-((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)(4-(5-methyl-1H-pyrazol-1-yl)phenyl)methanone
CAS:Pureza:99.0%Peso molecular:512.9299926757812Ref: 10-F545254
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultar6-(methylthio)-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:287.3999938964844Nifursol-15N2,d2
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled Nifursol (N458702). A medicinal, prophylactic additive in animal feeds, protecting poultry from histomoniasis.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Kowalski, P., et al.: J. Pharm. Biomed. Anal., 32, 937 (2003), Khlebnikov, A., et al.: Bioorg. Med. Chem., 16, 9302 (2008), Schepetkin, I., et al.: Mol. Pharmacol., 74, 392 (2008),<br></p>Fórmula:C12H5D2N315N2O9Cor e Forma:NeatPeso molecular:369.218-chloro-2-phenylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:283.70999145507814-(2-(4-CHLORO-5H-PYRROLO[2,3-D]PYRIMIDIN-7(6H)-YL)ETHYL)MORPHOLINE
CAS:Pureza:95.0%Peso molecular:268.752-[1-Methyl-5-(trifluoromethyl)pyrazol-3-yl]-thiophene-5-carboxaldehyde
CAS:Fórmula:C10H7F3N2OSCor e Forma:SolidPeso molecular:260.23Ref: 10-F538267
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarSodium (S)-6-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Pureza:97%Peso molecular:405.35000610351562-(2-chlorophenyl)-8-methylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:297.7399902343752-[5-(2-Fluorobenzoyl)-2-thienyl]acetonitrile
CAS:Fórmula:C13H8FNOSCor e Forma:SolidPeso molecular:245.275-(4-(2-(5-Ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione
CAS:Pureza:97.0%Peso molecular:370.4200134277344Ref: 10-F540283
1gA consultar2mg79,00€5mg128,00€10mg94,00€25mg120,00€50mg227,00€100mg412,00€250mgA consultar4-(furan-2-yl)-6-(5-methylthiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:257.30999755859375Tert-Butyl 4-(8-amino-5-isoquinolinyl)-1-piperazinecarboxylate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:328.4159851074219(2R,4R)-rel-1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid Methyl Ester
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications (2R,4R)-rel-1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid Methyl Ester is an impurity of Nifedipine (N457000); a dihydropyridine calcium channel blocker. Also used as an antihypertensive and antianginal.<br>References Karancsi, T., et al.: Acta Pharm. Hung., 66, 21 (1996); Poetter, H., et al.: J. Pharmaceut. Biomed., 6, 115 (1988); Ali, S.L., et al.: Anal. Profiles Drug Subs., 18, 221 (1989); Soons, P.A., et al.: J. Pharm. Biomed. Anal., 9, 475 (1991); Brown, M.J., et al.: Lancet, 356, 366 (2000)<br></p>Fórmula:C19H18N4O6Cor e Forma:NeatPeso molecular:398.376,7-Dimethoxy-2,3-dimethylquinoxaline
CAS:Pureza:95.0%Cor e Forma:Solid, Brown powderPeso molecular:218.255996704101563-Phenylquinoxaline-5-carboxylic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:250.25700378417974’-O-Benzyloxy Ezetimibe
CAS:Produto Controlado<p>Impurity Ezetimibe Benzyl Ether Impurity<br>Applications Protected Ezetimibe, used for the synthesis of related derivatives.<br>References Raman, B., et al.: J. Pharm. Biomed. Anal., 52, 73 (2010),<br></p>Fórmula:C31H27F2NO3Cor e Forma:NeatPeso molecular:499.555-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-3-carboxylic acid
CAS:Peso molecular:210.233001708984382-(2-methyl-1H-indol-3-yl)-N-(thiophen-2-ylmethyl)ethan-1-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:306.85000610351565-Benzo[1,3]dioxol-5-yl-1 H -pyrazole-3-carboxylic acid
CAS:Cor e Forma:SolidPeso molecular:232.19500732421875Benzarone
CAS:Produto Controlado<p>Applications Benzarone is an EYA (Eyes Absents), multifunctional protein involved in organogenesis, inhibitor which makes it a potent anticancer agent. EYA’s are over expressed in ovarian and breast cancers. As well it is involved in the synthesis of Human Uric Acid Transporter 1 inhibitors which may be used to treat kidney diseases.<br>References Tadjuidje, E. et al.: PLoS One., 7, 34806 (2012); M, Wempe, et al.: J. Med. Chem., 54, 2701 (2011);<br></p>Fórmula:C17H14O3Cor e Forma:NeatPeso molecular:266.29Selexipag
CAS:Produto Controlado<p>Applications Selexipag is an orally available, highly selective, long-acting prostacyclin (IP) receptor agonist prodrug. It is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Fórmula:C26H32N4O4SCor e Forma:Light YellowPeso molecular:496.62Enzalutamide Carboxylic Acid
CAS:<p>Applications Enzalutamide Carboxylic Acid is used as hormone therapies to prevent androgen-fuled growth of castrate-resistant prostate cancer.<br>References Tomasz, M.B., et al.: New Engl, J. Med., 424, 371 (2014);<br></p>Fórmula:C20H13F4N3O3SCor e Forma:NeatPeso molecular:451.39METHYL 1-CHLORO-4-HYDROXY-7-PHENOXYISOQUINOLINE-3-CARBOXYLATE
CAS:Pureza:90.0%Peso molecular:329.7399902343751-Methyl-3-phenylpiperazine
CAS:Produto Controlado<p>Applications Piperazine derivative used as reference materials for forensic laboratories. They affect the central and the autonomic nervous systems, the blood pressure, and smooth muscle.<br>References Brady, J., et al.: Drug Dev. Res., 20, 231 (1990), Winter, J., et al.: J. Pharmacol. Exp. Ther., 262, 682 (1992), Ator, N., et al.: Eur. J. Pharmacol., 241, 237 (1993), Forster, E., et al.: Eur. J. Pharmacol., 281, 81 (1995),<br></p>Fórmula:C11H16N2Cor e Forma:Off WhitePeso molecular:176.26Sitagliptin Carbamoyl β-D-Glucuronide Sodium Salt
CAS:Produto ControladoFórmula:C23H22F6N5NaO9Cor e Forma:NeatPeso molecular:649.43N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine
CAS:Pureza:95.0%Peso molecular:461.8800048828125N-Desmethyl Diphenhydramine Hydrochloride
CAS:<p>Applications N-Desmethyl Diphenhydramine is an impurity of Diphenhydramine (D486900) with antihistaminic activity.<br>References Nauta, W. T. et al.: Med. Chem., Spec. Contrib. Int. Symp., 3rd, 125 (1973);<br></p>Fórmula:C16H19NO·ClHCor e Forma:White To Light BeigePeso molecular:277.79Iso Loratadine
CAS:Produto Controlado<p>Impurity Loratadine EP Impurity E<br>Applications Iso Loratadine (Loratadine EP Impurity E) is a Loratadine (L469575) impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.<br>References Billah., et al.: Lipids, 26, 1172 (1991), Piwinski., et al.: J. Med. Chem., 34, 457 (1991),<br></p>Fórmula:C22H23ClN2O2Cor e Forma:NeatPeso molecular:382.884-Amino-N-(1-ethyl-3-piperidinyl)-5-(ethylsulfonyl)-2-methoxybenzamide
CAS:<p>Impurity Amisulpride EP Impurity G<br>Applications 4-Amino-N-(1-ethyl-3-piperidinyl)-5-(ethylsulfonyl)-2-methoxybenzamide is an impurity of Amisulpride (A633250). Amisulpride EP Impurity G<br></p>Fórmula:C17H27N3O4SCor e Forma:Off White PowderPeso molecular:369.4796-Methoxy-2-naphthol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 6-Methoxy-2-naphthol is a reactant in the development of sirtuin inhibitors from pyrazolone and isoxazol-5-one cambinol analogs.<br>References Mahajan, S.S., et. al.: J. Med. Chem., 57, 3283 (2014)<br></p>Fórmula:C11H10O2Cor e Forma:NeatPeso molecular:174.206-fluoro-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:259.29998779296875Methyl 3-((phenoxycarbonyl)amino)thiophene-2-carboxylate
CAS:Pureza:95%Peso molecular:277.29000854492192-(2,4-Dimethoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:320.3599853515625(R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:374.2340087890625Saxagliptin
CAS:Produto Controlado<p>Stability Temperature Sensitive<br>Applications Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.<br>References Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),<br></p>Fórmula:C18H25N3O2Cor e Forma:White SolidPeso molecular:315.41(S)-Bicalutamide
CAS:Produto Controlado<p>Applications (S)-Enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>Fórmula:C18H14F4N2O4SCor e Forma:WhitePeso molecular:430.374-isopropyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:283.39001464843753-(3,5-Dimethyl-pyrazol-1-yl)-benzoic acid
CAS:Fórmula:C12H12N2O2Pureza:95.0%Cor e Forma:SolidPeso molecular:216.24
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