Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65615 produtos de "Derivados de Quinazolina e Quinolina"
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Propylthiouracil
CAS:Produto Controlado<p>Applications Antihyperthyroid. Has been used to promote fattening. This substance is reasonably anticipated to be a human carcinogen.<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 6, 457 (1977), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984),<br></p>Fórmula:C7H10N2OSCor e Forma:White To Off-WhitePeso molecular:170.23N-(3-Chloroquinoxalin-2-yl)-4-methylbenzenesulfonamide
CAS:Pureza:95.0%Peso molecular:333.7900085449219Dextrosimendan
CAS:Produto Controlado<p>Applications Dextrosimendan is an isomer and impurity of Levosimendan (L378000), a bioactive enantiomer of Simendan (S466000). Levosimendan is a positive inotropic agent with vasodilating activity.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)<br></p>Fórmula:C14H12N6OCor e Forma:Yellow To Dark YellowPeso molecular:280.28Lumiracoxib
CAS:Produto Controlado<p>Applications Lumiracoxib is a selective cyclooxygenase-2-(COX-2) inhibitor and an anti-inflammatory agent (1,2,3,4).<br>References (1) Bitner, M., et al.: Int. J. Clin. Pract., 58, 340 (2004) (2) Packman, E., et al.: Headache, 45, 1163 (2005) (3) Rordorf, C.M., et al.: Clin. Pharmacokinet., 44. 1247 (2005) (4) Schnitzer, T.J., et al.: Curr. Med. Res. Opin., 21, 151 (2005)<br></p>Fórmula:C15H13ClFNO2Cor e Forma:NeatPeso molecular:293.722-Hydroxymethyl Olanzapine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A minor metabolite of Olanzapine.<br>References Moore, N., et al.: J. Pharmacol. Exper. Ther., 262, 545 (1992), Chiu, J., et al.: J. Pharmaceut. Biomed. Anal., 14, 609 (1996), Kassahun, K., et al.: Drug Metab. Dispos., 25, 81 (1997),<br></p>Fórmula:C17H20N4OSCor e Forma:NeatPeso molecular:328.433,5,6-Trihydroxy-1-isopropylindole
CAS:Produto Controlado<p>Applications 3,5,6-Trihydroxy-1-isopropylindole is an impurity of Isoproterenol (I874200), which is a non-selective beta-adrenergic agonist. Isoproterenol is used in the treatment of bradycardia; bronchodilator.<br>References Kikkawa, H. et al.: Biol. Pharmac. Bull., 17, 1047 (1994); Kral, P. et al.: Psychopharmacologia, 26, 79 (1972); Giles, R.E. et al.: J. Pharmacol. Exp. Ther., 186, 472 (1973);<br></p>Fórmula:C11H13NO3Cor e Forma:NeatPeso molecular:207.226(S)-4-Hydroxy Mephenytoin
CAS:Produto Controlado<p>Applications The S-enantiomer metabolite of Mephenytoin (M225000).<br>References Boobis, A., et al.: Cancer Res., 54, 89 (1994), Beresford, A., et al.: Xenobiotica, 27, 159 (1997), Zhu, B., et al.: Clin. Pharmacol. Ther., 70, 455 (2001), Jerdi, M., et al.: J. Pharm. Biomed. Anal., 35, 1203 (2004),<br></p>Fórmula:C12H14N2O3Cor e Forma:White To Off-WhitePeso molecular:234.25(4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
CAS:Produto Controlado<p>Applications A HMG-CoA reductase inhibitor intermediate.<br>References Hummel, W., et al.: J. Microbiol. Methods, 9, 201 (1989), Jendralla, H., et al.: J. Med. Chem., 34, 2962 (1991), Vicenzi, J., et al.: Enzyme Microb. Technol., 20, 494 ( 1997),<br></p>Fórmula:C13H23ClO4Cor e Forma:NeatPeso molecular:278.77Dexpramipexole
CAS:<p>Dexpramipexole ((R)-Pramipexole) is a mitochondrial protective agent that maintains mitochondrial function and energy production.</p>Fórmula:C10H17N3SPureza:99.78%Cor e Forma:SolidPeso molecular:211.33Furazolidone
CAS:<p>Applications Antimicrobial.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Yurchenco, J.A., et al.: Antimicrob. Chemother., 3, 1035 (1953), Sharma, C., et al.: J. Clin. Microbiol., 36, 756 (1998),<br></p>Fórmula:C8H7N3O5Cor e Forma:YellowPeso molecular:225.166-bromo-N-(pyridin-2-ylmethyl)benzo[d]thiazol-2-amine
CAS:Pureza:95.0%Peso molecular:320.20999145507815-Morpholin-4-yl-1,3,4-oxadiazol-2-ylamine
CAS:Fórmula:C6H10N4O2Pureza:95.0%Cor e Forma:SolidPeso molecular:170.172(R)-Lansoprazole
CAS:<p>Stability Hygroscopic<br>Applications The R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Fórmula:C16H14F3N3O2SCor e Forma:Off White To Dark BrownPeso molecular:369.36Hydroxy Atrazine
CAS:Produto Controlado<p>Applications Hydroxy Atrazine is a major metabolite of Atrazine (A794600).<br>References Thurman, E., et al.: Environ. Sci. Technol., 26, 2440 (1992), Evgenidou, E., et al.: J. Agric. Food Chem., 50, 6423 (2002), Namiesnik, J., et al.: Anal. Bioanal. Chem., 381, 279 (2005), Hultgren, S., et al.: Anal. Bioanal. Chem., 393, 929 (2009),<br></p>Fórmula:C8H15N5OCor e Forma:White To Off-WhitePeso molecular:197.24Ref: 10-F375506
1gA consultar2gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultar2-(Acetylamino)-6-[[[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]amino]carbonyl]-benzoic Acid
CAS:Produto ControladoFórmula:C22H26N2O8SCor e Forma:NeatPeso molecular:478.522-[[2-2(2-Amino-4-thiazolyl)acetyl]amino]-4-thiazoleacetic Acid
CAS:Produto ControladoFórmula:C10H10N4O3S2Cor e Forma:NeatPeso molecular:114.142Metaflumizone
CAS:<p>Applications Metaflumizone is a semicarbazone insecticide that works by blocking sodium channel in target insects resulting in paralyzation associated with blocking nerve activity. Metaflumizone is useful as a heartworm control treatment.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, Zhe,, et al.: J. Integrat. Agri. 11, 1145 (2012); Kuhn, D., et al.: Modern. Crop. Protect. Compound., 3, 1273 (2012);<br></p>Fórmula:C24H16F6N4O2Cor e Forma:WhitePeso molecular:506.403-Methyl-1-{4-[4-(propan-2-yl)benzenesulfonyl]phenyl}-1H-pyrazol-5-amine
CAS:Pureza:97%Peso molecular:355.4599914550781rac Sulpiride
CAS:Produto Controlado<p>Applications An antipsychotic drug used in the treatment of Schozophrenia and depression.<br>References Kramer, P., et al.: J. Neurosci., 31, 126 (2011), Alelyunas, Y., et al.: Bioorg. Med. Chem. Lett., 20, 7312, (2010),<br></p>Fórmula:C15H23N3O4SCor e Forma:Off-WhitePeso molecular:341.432,3-Di-furan-2-yl-quinoxaline-6-carboxylic acid
CAS:Cor e Forma:SolidPeso molecular:306.27700805664067-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid, 90%
CAS:Produto Controlado<p>Impurity Norfloxacin EP Impurity A; Norfloxacin USP Related Compound A (7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-d<br>Applications 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid (Norfloxacin EP Impurity A) is a Norfloxacin intermediate. Norfloxacin EP Impurity A; Norfloxacin USP Related Compound A (7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid).<br>References Piganeau, N., et al.: J. Mol. Biol., 312, 1177 (2001), Rameshkumar, N., et al.: Eur. J. Med. Chem., 38, 1001 (2003), You, Q., et al.: J. Med. Chem., 52, 5649 (2009),<br></p>Fórmula:C12H9ClFNO3Pureza:90%Cor e Forma:NeatPeso molecular:269.665-(4-CHLOROPHENYL)-1-(2-METHOXYPHENYL)-1H-PYRAZOL-3(2H)-ONE
CAS:Pureza:95.0%Peso molecular:300.7399902343754-(4-ETHYNYLPHENYL)MORPHOLINE
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:187.242004394531252-imino-5-oxo-4-(thiophen-2-yl)-3,4,5,6,7,8-hexahydro-2H-1-benzopyran-3-carbonitrile
CAS:Pureza:95+%Peso molecular:272.32000732421875Ethyl 2-(4-fluorobenzamido)-4-(p-tolyl)thiophene-3-carboxylate
CAS:Pureza:98%Peso molecular:383.440002441406254-Bromo-1-ethyl-1 H -pyrazole-3-carboxylic acid methyl ester
CAS:Fórmula:C7H9BrN2O2Pureza:96%Cor e Forma:SolidPeso molecular:233.0654-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
CAS:Produto Controlado<p>Applications 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.<br>References Mross, K., et al.: Clin. Cancer Res., 18, 2658 (2012); Stiehl, J., et al. Process for Preparation of Regorafenib. PCT Int. Appl. 2011128261. Oct 20, 2011; Van Cutsem, E., et al.: J. Clin. Oncol., 30, 3502 (2012)<br></p>Fórmula:C13H12FN3O2Cor e Forma:Dark Orange To Red BrownPeso molecular:261.25rac Kynurenine
CAS:Produto Controlado<p>Applications A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan.<br>References Swartz, K., et al.: J. Neurosci., 10, 2965 (1990), Hasegawa, H., et al.: Anal. Bioanal. Chem., 377, 886 (2003), Tsai, Y., et al.: Anal. Biochem., 319, 34 (2003), Mitsuhashi, S., et al.: Anal. Chim. Acta, 584, 315 (2007),<br></p>Fórmula:C10H12N2O3Cor e Forma:NeatPeso molecular:208.21Famotidine Sulfoxide
CAS:Produto Controlado<p>Applications An intermediate in the synthesis of the metabolite of the drug Famotidine (F102250(P)), which is a histamine H2-receptor antagonist and an antiulcerative.<br>References Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982), Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984), Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985),<br></p>Fórmula:C8H15N7O3S3Cor e Forma:NeatPeso molecular:353.447-Nitro-4-(pyridin-2-ylmethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
CAS:Pureza:95+%Peso molecular:285.2590026855469Ref: 10-F608382
1gA consultar2gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultarBupivacaine Related Compound B
CAS:Produto Controlado<p>Applications Bupivacaine Related Compound B (cas# 65797-42-4) is used as a reactant in the preparation of Ropivacaine hydrochloride monohydrate.<br>References Jaksch, P.: PCT Int. Appl. 16 pp. (1996)<br></p>Fórmula:C14H20N2O·ClHCor e Forma:Off-WhitePeso molecular:268.784-Chloro-1H -pyrazol-3-ylamine hydrochloride
CAS:Fórmula:C3H5Cl2N3Pureza:95.0%Cor e Forma:SolidPeso molecular:153.99Carvedilol
CAS:Produto Controlado<p>Applications Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996);<br></p>Fórmula:C24H26N2O4Cor e Forma:WhitePeso molecular:406.47Dehydropinaverium Bromide
CAS:<p>Applications 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethoxy]ethyl]morpholinium Bromide (1:1), is the derivative of Pinaverium Bromide (P465000), which is spasmolytic agent with low incidence of anticholinergic effects. It is a drug used for functional gastrointestinal disorders.<br>References Jacquot, C., et al.: Eur. J. Med. Chem., 13, 61 (1978), Bretaudeau, J., et al.: J. Pharmacol., 11, 233 (1980), Bertrand, J., et al.: Therapie, 36, 555 (1981),<br></p>Fórmula:C26H39BrNO4·BrCor e Forma:NeatPeso molecular:589.40Gabapentin Enacarbil Sodium Salt
CAS:Produto Controlado<p>Applications Gabapentin enacarbil is a prodrug of the anticonvulsant gabapentin (G117250).<br>References Cundy, K., et al.: J. Pharmacol. Exp. Ther., 311, 315 (2004); Lal, R., et al.: Clin. Ther., 31, 1776 (2009)<br></p>Fórmula:C16H26NO6·NaCor e Forma:NeatPeso molecular:351.373-(3,5-Dimethyl-pyrazol-1-yl)-propionic acid hydrazide
CAS:Fórmula:C8H14N4OPureza:95.0%Cor e Forma:SolidPeso molecular:182.227Spiromesifen
CAS:Produto Controlado<p>Applications Spiromesifen is a useful insecticide and miticide in plant breeding. Also useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C23H30O4Cor e Forma:Light BrownPeso molecular:370.48Sarafloxacin
CAS:<p>Applications Sarafloxacin is a quinolone antibiotic drug that was discontinued in 2001. Useful for biological studies and can be detected with colloidal gold test strips.<br>References Jia, F., et al.: Agric. Biotechnol., 8, 172 (2019)<br></p>Fórmula:C20H17F2N3O3Cor e Forma:Light YellowPeso molecular:385.36O-Desmethyl Diltiazem Hydrochloride
CAS:Produto Controlado<p>Impurity Diltiazem EP Impurity C (HCl)<br>Applications A metabolite of Diltiazem (D460620), an antianginal, antihypertensive pharmaceutical. Diltiazem EP Impurity C (HCl).<br>References Li, R., et al.: J. Med. Chem., 35, 3246 (1992),<br></p>Fórmula:C21H25ClN2O4SCor e Forma:NeatPeso molecular:436.952-(2,4-Dimethoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:320.3599853515625O-Des(2-dimethylaminoethyl)-O-methyl Itopride
CAS:Produto Controlado<p>Applications O-Des(2-dimethylaminoethyl)-O-methyl Itopride is an impurity of Itopride (I931500, HCl); a dopamine D2-receptor antagonist with anticholinesterase activity. Also gastroprokinetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Iwanaga, Y., et al; Jpn. J. Pharmacol., 56, 261 (1991); Mushiroda, T., et al.: Drug Metab. Dispos., 28, 1231 (2000)<br></p>Fórmula:C17H19NO4Cor e Forma:Off-WhitePeso molecular:301.34α,α,α',5-Tetramethyl-1,3-benzenediacetonitrile
CAS:Produto ControladoFórmula:C14H16N2Cor e Forma:NeatPeso molecular:212.296-Bromo-N-methylquinazolin-2-amine
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:238.087997436523445-(benzo[d]thiazol-2-yl)thiophene-2-carbonyl chloride
CAS:Pureza:95.0%Peso molecular:279.7600097656252-Picoline
CAS:Produto Controlado<p>Applications 2-Picoline is used as a reagent in the synthesis of 2-Picolineborane, a non-toxic alternative to sodium borohydride for the labelling of oligosaccharides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Renee Ruhaak, L., et al.: Proteomics, 10, 2330 (2010)<br></p>Fórmula:C6H7NCor e Forma:NeatPeso molecular:93.133-(2,6-Dimethylmorpholino)-1,1,1-trifluoro-2-propanol
CAS:Fórmula:C9H16F3NO2Cor e Forma:SolidPeso molecular:227.227Linagliptin-d3
CAS:<p>Applications Linagliptin-d3 is the isotope labelled analogue of a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Fórmula:C25D3H25N8O2Cor e Forma:NeatPeso molecular:475.5612,2,2-Trifluoroethyl 2,5-Bis(2,2,2-trifluoroethoxy)benzoate
CAS:Produto Controlado<p>Applications Intermediate in the production of antiarrhythmic N-(Piperidylalkyl)trifluoroethoxybenzamides. Possible Flecainide impurity.<br>References Banitt, E., et al.: J. Med. Chem., 20, 821 (1977),<br></p>Fórmula:C13H9F9O4Cor e Forma:NeatPeso molecular:400.19Amoxapine
CAS:<p>Applications Antidepressant.<br>References Takahashi, R., et al.: J. Int. Med. Res., 7, 7 (1979), Jue, S.G., et al.: Drugs 24, 1 (1982)<br></p>Fórmula:C17H16ClN3OCor e Forma:White To Light BeigePeso molecular:313.782-Pyridin-3-yl-benzofuran-5-carboxylic acid methyl ester
Pureza:95.0%Peso molecular:253.25700378417972-(Pyridin-3-yl)-1H-benzo[d]imidazole
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:195.22500610351562(R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:374.23400878906257-(But-2-yn-1-yl)-3-methyl-8-(methylamino)-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione
CAS:Produto Controlado<p>Applications 7-(But-2-yn-1-yl)-3-methyl-8-(methylamino)-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione is an impurity of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Fórmula:C21H21N7O2Cor e Forma:NeatPeso molecular:403.437rac-Desmethyl Irinotecan Hydrochloride
CAS:Produto Controlado<p>Impurity Irinotecan Related Compound C<br>Stability Hygroscopic<br>Applications Desmethyl Irinotecan Hydrochloride is an impurity in the synthesis of Irinotecan Hydrochloride (I767500), a DNA topoisomerase inhibitor.<br>References Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987), Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993);<br></p>Fórmula:C32H36N4O6·ClHCor e Forma:Light Yellow To YellowPeso molecular:609.11Regorafenib (Pyridine)-N-oxide
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Regorafenib (Pyridine)-N-oxide is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilhelm, S.: PCT Int. Appl. WO 2011130728 A1 20111020. Oct 20, 2011<br></p>Fórmula:C21H15ClF4N4O4Cor e Forma:NeatPeso molecular:498.814-isopropyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:283.3900146484375Quinoline Yellow (Technical Grade)
CAS:<p>Stability Hygroscopic<br>Applications Quinoline yellow, is a yellow powder used in lipstick, lotion, soap, shampoo, bubble bath, ingested drugs, and applied drugs applications.<br></p>Fórmula:C18H9NNa2O8S2Cor e Forma:NeatPeso molecular:477.38Rivaroxaban
CAS:<p>Applications A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Fórmula:C19H18ClN3O5SCor e Forma:White To BeigePeso molecular:435.882-Deschloro Aripiprazole
CAS:<p>Impurity Aripiprazole EP Impurity D<br>Applications 2-Deschloro Aripiprazole (Aripiprazole EP Impurity D) is an impurity of the antipsychotic agent Aripiprazole (A771000). Aripiprazole impurity B.<br>References Akaike, A., et al.: Brain Res., 418, 262 (1987); Kikuchi, K., et al.: Life Sci., 42, 343 (1988); Caprathe, B., et al.: J. Med. Chem., 34, 2736 (1991); Yamada, S., et al.: J. Pharm. Pharmacol., 49, 206 (1997);<br></p>Fórmula:C23H28ClN3O2Cor e Forma:WhitePeso molecular:413.943-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline
CAS:Produto Controlado<p>Applications Intermediate in the preparation of Nilotinib.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, G., et al.: Bioorg. Med. Chem. Lett., 19, 6691 (2009), Seeliger, M., et al.: Cancer Res., 69, 2384 (2009),<br></p>Fórmula:C11H10F3N3Cor e Forma:NeatPeso molecular:241.212-(4-Fluoro-phenyl)-quinoline-4-carboxylic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:267.25900268554694-[6-(7-Cyclopentyl-6-dimethylcarbamoyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester
CAS:Pureza:98%Peso molecular:534.6649780273438Bupivacaine
CAS:<p>Bupivacaine (AH-250) is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels</p>Fórmula:C18H28N2OPureza:99.83%Cor e Forma:SolidPeso molecular:288.43Valsartan
CAS:<p>Stability Hygroscopic<br>Applications A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C24H29N5O3Cor e Forma:NeatPeso molecular:435.52Rotigotine
CAS:<p>Rotigotine (1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-) is an antiparkinson agent and dopamine receptor agonist.</p>Fórmula:C19H25NOSPureza:99.04% - 99.88%Cor e Forma:SolidPeso molecular:315.47Palbociclib-d4
CAS:Produto Controlado<p>Applications Palbociclib-d4 is an isotope labelled compound of Palbociclib (P139900). Palbociclib (P139900) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.<br>References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)<br></p>Fórmula:C24H25D4N7O2Cor e Forma:Light YellowPeso molecular:451.565-(PYRIDIN-4-YL)-2,3-DIAZABICYCLO[4.2.0]OCTA-1,5-DIEN-4-ONE
CAS:Pureza:95.0%Peso molecular:199.21299743652344(6-bromo-2-methoxyquinolin-3-yl)(3-chloro-4-fluorophenyl)methanol
CAS:Pureza:95.0%Peso molecular:396.6400146484375(R)-Rabeprazole Sodium Salt
CAS:Produto Controlado<p>Applications A partially reversible gastric proton pump inhibitor.<br>References Moda, T., et al.: Lett. Drug Des. Discov., 4, 502 (2007), Belaz, K., et al.: J. Pharm. Biomed. Anal., 47, 81 (2008),<br></p>Fórmula:C18H20N3NaO3SCor e Forma:NeatPeso molecular:381.423-(1-Benzyl-4-hydroxypiperidin-4-yl)-2-chloroquinoline
CAS:Pureza:98%Peso molecular:352.85998535156252-methyl-2-(4-morpholinyl)propanoic acid hydrochloride hydrate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:227.690002441406252-Mercaptobenzimidazole
CAS:Produto Controlado<p>Impurity Rabeprazole EP Impurity F<br>Applications An antidegradant, protecting rubber from oxidation. An intermediate in the synthesis of Rabeprazole (R070500)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Beheshti, A., et al.: J. Food Sci., 75, C135 (2010), Rohrig, U., et al.: J. Med. Chem., 53, 1172 (2010),<br></p>Fórmula:C7H6N2SCor e Forma:NeatPeso molecular:150.202-Amino-4-(4-cyclohexyl-phenyl)-thiophene-3-carboxylic acid methyl ester
CAS:Fórmula:C18H21NO2SPureza:97%Cor e Forma:SolidPeso molecular:315.432,5-Dioxopyrrolidin-1-yl 6-hydrazinylnicotinate hydrochloride
CAS:Pureza:98%Peso molecular:286.67001342773446-(methylsulfonyl)-N-(pyridin-3-ylmethyl)benzo[d]thiazol-2-amine
CAS:Pureza:95.0%Peso molecular:319.3999938964844Ticagrelor
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Fórmula:C23H28F2N6O4SCor e Forma:WhitePeso molecular:522.57Clozapine-d4
CAS:Produto Controlado<p>Applications Clozapine-d4 can act as modulators of dopamine receptors, serotonin receptors, adrenergic receptors, acetylcholine receptors, and/or histamine receptors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gant, T. G., U.S. Pat. Appl. Publ. (2010), US 20100166887 A1, 20100701<br></p>Fórmula:C182H4H15ClN4Cor e Forma:Light Yellow To YellowPeso molecular:330.854,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
CAS:<p>Applications 4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Fórmula:C19H17Cl2N3O5SCor e Forma:NeatPeso molecular:470.33(S)-N-(1-Amino-1-oxobutan-2-yl)-4-chlorobutanamide
CAS:<p>Impurity Levetiracetam USP Related Compound A<br>Applications (S)-N-(1-Amino-1-oxobutan-2-yl)-4-chlorobutanamide is a related compound of Levetiracetam (L331500). Levetiracetam related compound A. Levetiracetam USP Related Compound A.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C8H15ClN2O2Cor e Forma:White To Off-WhitePeso molecular:206.67N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride
CAS:Produto Controlado<p>Applications Hydrochloride Salt of N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester is an intermediate in the preparation of angiotensin II type 1 receptor antagonists.<br>References Goossen, L.J. et al.: J. Org. Chem., 72, 7473 (2007); Nie, Y. et al.: Bioorg. Med. Chem., 20, 2747 (2012);<br></p>Fórmula:C20H22N2O2·ClHCor e Forma:NeatPeso molecular:358.86
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