Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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Sonidegib
CAS:<p>Sonidegib (Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.</p>Fórmula:C26H26F3N3O3Pureza:98% - 99.97%Cor e Forma:SolidPeso molecular:485.5Doxycycline
CAS:<p>Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity.</p>Fórmula:C22H24N2O8Pureza:97.51% - 99.88%Cor e Forma:Yellow Crystalline Powder SolidPeso molecular:444.43Emorfazone
CAS:Emorfazone (PH011085) has an anti-nociceptive effect.Fórmula:C11H17N3O3Pureza:99.89%Cor e Forma:SolidPeso molecular:239.27Vilazodone Hydrochloride
CAS:<p>Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the</p>Fórmula:C26H27N5O2·HClPureza:99.56% - >99.99%Cor e Forma:SolidPeso molecular:477.99Ivacaftor
CAS:<p>Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,</p>Fórmula:C24H28N2O3Pureza:99% - 99.98%Cor e Forma:SolidPeso molecular:392.49Apremilast
CAS:Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.Fórmula:C22H24N2O7SPureza:98.13% - 99.95%Cor e Forma:SolidPeso molecular:460.50Piperaquine tetraphosphate tetrahydrate
CAS:<p>Piperaquine tetraphosphate tetrahydrate is a potent anti-parasites agent.</p>Fórmula:C29H32Cl2N6·4H3O4P·4H2OPureza:99.29%Cor e Forma:SolidPeso molecular:999.6Buclizine
CAS:<p>Buclizine is an orally active antihistamine, antiallergic compound. buclizine is also a strong teratogen in rats and exhibits antitumour effects.</p>Fórmula:C28H33ClN2Cor e Forma:SolidPeso molecular:433.03X-376
CAS:<p>X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase ALK with potential antineoplastic activity.</p>Fórmula:C25H25Cl2FN6O3Pureza:97.87%Cor e Forma:SolidPeso molecular:547.41Dovitinib
CAS:<p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>Fórmula:C21H21FN6OPureza:99.35% - 99.92%Cor e Forma:SolidPeso molecular:392.43Triolein
CAS:<p>Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.</p>Fórmula:C57H104O6Pureza:99.76% - 99.99%Cor e Forma:Clear Yellowish LiquidPeso molecular:885.43Astragaloside IV
CAS:<p>Astragaloside IV suppresses ERK1/2, JNK, MMP-2/9 in breast cancer; inhibits adenovirus and protects cardiovascular, immune, digestive, nervous systems.</p>Fórmula:C41H68O14Pureza:99% - 99.84%Cor e Forma:Hydroscopic Brown Or Yellow PowderPeso molecular:784.97Oclacitinib
CAS:<p>Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000</p>Fórmula:C15H23N5O2SPureza:98% - 98.45%Cor e Forma:White To Off-White SolidPeso molecular:337.44Fenoldopam mesylate
CAS:<p>Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties.</p>Fórmula:C16H16ClNO3·CH4O3SPureza:99.19%Cor e Forma:SolidPeso molecular:401.86Apixaban
CAS:<p>Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.</p>Fórmula:C25H25N5O4Pureza:99.73% - 99.93%Cor e Forma:SolidPeso molecular:459.5Anagrelide hydrochloride
CAS:<p>Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.</p>Fórmula:C10H7Cl2N3O·HClPureza:99.58%Cor e Forma:Off-White PowderPeso molecular:292.55Cabozantinib
CAS:<p>Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).</p>Fórmula:C28H24FN3O5Pureza:99.68% - 99.88%Cor e Forma:SolidPeso molecular:501.51SB-3CT
CAS:<p>SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).</p>Fórmula:C15H14O3S2Pureza:98% - 99.38%Cor e Forma:SolidPeso molecular:306.4Cinitapride
CAS:<p>Cinitapride (Blaston) treats acid reflux and gastric issues, targeting 5-HT2, 5-HT1, and 5-HT4 receptors.</p>Fórmula:C21H30N4O4Pureza:99.52%Cor e Forma:SolidPeso molecular:402.49Mosapride Citrate
CAS:<p>Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.</p>Fórmula:C21H25ClFN3O3·C6H8O7Pureza:99.70%Cor e Forma:White PowderPeso molecular:614.02T-5224
CAS:<p>T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription</p>Fórmula:C29H27NO8Pureza:97.88% - 99.29%Cor e Forma:SolidPeso molecular:517.53
