Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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Ethyl 2-Chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
CAS:Produto Controlado<p>Applications Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (cas# 27143-07-3) is a useful research chemical.<br></p>Fórmula:C11H13N2O3ClCor e Forma:NeatPeso molecular:256.683',4'-Dihydroxyacetophenone
CAS:Produto Controlado<p>Applications 3',4'-Dihydroxyacetophenone is an active constituent of Chinese medicine and also has antimelanogenic actiivity.<br>References Kim. Y., et al.: Biosci., Biotech., Biochem., 70, 532 (2006); Yang, D., et al.: Prostaglandins, 38, 497 (1989)<br></p>Fórmula:C8H8O3Cor e Forma:NeatPeso molecular:152.15trans-4-Aminocyclohexanol
CAS:<p>Applications trans-4-Aminocyclohexanol, used in the preparation of potential hypertensive agents and other biologically active compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chan, K.L. et al.: As. J. Pharmacol. Sci., 1, 91 (1979);<br></p>Fórmula:C6H13NOCor e Forma:NeatPeso molecular:115.1744-Hydroxy Omeprazole Preparation Kit
CAS:Produto ControladoFórmula:C16H17N3O3SCor e Forma:Off White SolidPeso molecular:331.396-Allyl-8b-carboxyergoline
CAS:<p>Impurity Cabergoline EP Impurity A<br>Applications 6-Allyl-8β-carboxyergoline is a metabolite of cabergoline (C050000) which is a dopamine D2-receptor agonist.<br>References Brambilla, E., et al.: Eur. J. Med. Chem., 24, 421 (1989), Ferrari, C., et al.: J. Clin. Endocrinol. Metab., 68, 1201 (1989), Hutton, J.T., et al.: Neurology, 46, 1062 (1996)<br></p>Fórmula:C18H20N2O2Cor e Forma:Light Beige SolidPeso molecular:296.36366,7-DIMETHOXY-2-METHYL-4-(PIPERAZIN-1-YL)QUINAZOLINE
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:288.35101318359375S-Methyldihydroziprasidone
CAS:Produto Controlado<p>Applications S-Methyldihydroziprasidone is a metabolite of Ziprasidone (Z485000) and is used for the treatment of psychiatric and ocular disorders.<br>References Obach, R.S., et al.: Xenobiotica, 42, 1049 (2012); Prakash, C., et al.: Drug Metab. Dispos., 25, 863 (1997); Prakash, C., et al. S-Methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders. PCT Int. Appl. WO 2001091756 A2 20011206. Dec 6, 2001<br></p>Fórmula:C22H25ClN4OSCor e Forma:NeatPeso molecular:428.98Ticagrelor Epimer
Produto Controlado<p>Applications Ticagrelor Epimer is an epimer impurity of Ticagrelor (T437700). Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Fórmula:C23H28F2N6O4SCor e Forma:NeatPeso molecular:522.57(S) FTY720 Phosphate
CAS:<p>Applications FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720-phosphate.<br>References Chiba, K., et al.: J. Immunol., 160, 5037 (1998), Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002), Kiuchi, M., et al.: Bioorganic & Medicinal Chemistry, 13, 425 (2005<br></p>Fórmula:C19H34NO5PCor e Forma:WhitePeso molecular:387.45DL-erythro Ritalinic Acid-d10 (Major)
CAS:Produto ControladoFórmula:C13H7D10NO2Cor e Forma:NeatPeso molecular:229.345-Aminoimidazole-4-carboxamide Lactose Adduct
Produto Controlado<p>Stability Hygroscopic<br>Applications 5-Aminoimidazole-4-carboxamide Lactose Adduct is a lactose adduct of 5-Aminoimidazole-4-carboxamide (A611690), a metabolite of Temozolomide (T017775).<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999)<br></p>Fórmula:C16H26N4O11Cor e Forma:NeatPeso molecular:450.4trans-Haloperidol N-Oxide
CAS:Produto Controlado<p>Applications trans-Haloperidol N-Oxide is the trans-isomer of Haloperidol N-Oxide (H103735), a metabolite of Haloperidol (H103700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gorrod, J., et al.: Xenobiotica., 23, 495 (1993); Monser, L., et al.: J. Liquid. Chromatograph. Technol., 26, 261 (2003);<br></p>Fórmula:C21H23ClFNO3Cor e Forma:NeatPeso molecular:391.863-(1-Benzyl-4-hydroxypiperidin-4-yl)-2-chloroquinoline
CAS:Pureza:98%Peso molecular:352.8599853515625(R)-Rabeprazole Sodium Salt
CAS:Produto Controlado<p>Applications A partially reversible gastric proton pump inhibitor.<br>References Moda, T., et al.: Lett. Drug Des. Discov., 4, 502 (2007), Belaz, K., et al.: J. Pharm. Biomed. Anal., 47, 81 (2008),<br></p>Fórmula:C18H20N3NaO3SCor e Forma:NeatPeso molecular:381.42Palbociclib-d4
CAS:Produto Controlado<p>Applications Palbociclib-d4 is an isotope labelled compound of Palbociclib (P139900). Palbociclib (P139900) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.<br>References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)<br></p>Fórmula:C24H25D4N7O2Cor e Forma:Light YellowPeso molecular:451.56Selexipag
CAS:Produto Controlado<p>Applications Selexipag is an orally available, highly selective, long-acting prostacyclin (IP) receptor agonist prodrug. It is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Fórmula:C26H32N4O4SCor e Forma:Light YellowPeso molecular:496.621-Pyridin-4-yl-2-(triphenyl-λ*5*-phosphanylidene)-ethanone
Pureza:95.0%Peso molecular:381.41500854492193-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Produto Controlado<p>Impurity Risperidone EP Impurity L<br>Applications 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity L) is an intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Fórmula:C11H15ClN2OCor e Forma:NeatPeso molecular:226.702-Methyl-Celecoxib
CAS:Produto Controlado<p>Impurity 2,4-Dimethyl Celecoxib Impurity<br>Applications 2-Methyl-Celecoxib is an analog of the anti-inflammatory drug Celecoxib (C251000). Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor.<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Fórmula:C18H16F3N3O2SCor e Forma:Off-White To BeigePeso molecular:395.4Levomepromazine EP Impurity D
Produto ControladoFórmula:C32H33N3O2S2Cor e Forma:NeatPeso molecular:555.8Nadolol
CAS:Produto Controlado<p>Applications β-Adrenergic blocker. Antihypertensive; antianginal.<br>References Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977), Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978), Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980),<br></p>Fórmula:C17H27NO4Cor e Forma:Off-WhitePeso molecular:309.40Gefitinib-d6
CAS:Produto Controlado<p>Applications Gefitinib-d6 is the labeled version of Gefitinib (G304000), which is an antineoplastic.<br>References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001), Hirata, A., et al.: Cancer Res., 62, 2554 (2002), Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003), Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005)<br></p>Fórmula:C22D6H18ClFN4O3Cor e Forma:NeatPeso molecular:452.9393-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity D)
CAS:<p>Impurity Domperidone EP Impurity D<br>Applications An impurity of the gastrokinetic and antinauseant drug Domperidone (D531100).<br></p>Fórmula:C32H34ClN7O3Pureza:>90%Cor e Forma:White To Off-WhitePeso molecular:600.11Ref: 10-F721211
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarValsartan
CAS:<p>Stability Hygroscopic<br>Applications A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C24H29N5O3Cor e Forma:NeatPeso molecular:435.52Boc-L-Nitroarginine
CAS:Produto Controlado<p>Applications Boc-L-Nitroarginine, can be used in peptide chemistry. It has been also shown to act as NO synthase inhibitor, and thus used in the study of The effects of methylene blue (MB) for treatment of sepsis induced by bowel perforation.<br>References Galili, Y. Euro. surg. Rese. vol. 29, P:390-395 (19997);<br></p>Fórmula:C11H21N5O6Cor e Forma:NeatPeso molecular:319.31Dihydrodiol Ibrutinib
CAS:Produto Controlado<p>Applications Dihydrodiol Ibrutinib is a metabolite of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.<br>References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)<br></p>Fórmula:C25H26N6O4Cor e Forma:NeatPeso molecular:474.513-Chloro-4-morpholino-1,2,5-thiadiazole
CAS:Produto Controlado<p>Impurity Timolol EP Impurity F; Timolol BP Impurity F; Timolol USP Related Compound F<br>Applications 3-Chloro-4-morpholino-1,2,5-thiadiazole (Timolol EP Impurity F; Timolol BP Impurity F; Timolol USP Related Compound F) is an intermediate for the synthesis of Timolol.<br>References Wasson, B., et al.: J. Med. Chem., 15, 651 (1972), Tokunaga, M., et al.: Sci., 277, 936 (1997),<br></p>Fórmula:C6H8ClN3OSCor e Forma:White To Off-WhitePeso molecular:205.67N-Nitroso-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valine Methyl Ester-d8
Fórmula:C20H13D8N3O3Cor e Forma:NeatDesethylene Norfloxacin Hydrochloride
CAS:<p>Impurity Norfloxacin EP Impurity B<br>Applications Desethylene Norfloxacin (Norfloxacin EP Impurity B) is a degradation intermediate from Norfloxin (N681000), an fluorinated quinolone antibacterial agent.<br>References Prieto, A., et al.: Biores. Technol., 102, 10987 (2011); Koga, H., et al.: J. Med. Chem., 23, 1358 (1980);<br></p>Fórmula:C14H16FN3O3·ClHCor e Forma:Off-White To YellowPeso molecular:329.752-Amino-4-thiazoleacetic Acid
CAS:Produto ControladoFórmula:C5H6N2O2SCor e Forma:NeatPeso molecular:158.18Hydroxy Brimonidine Trifluoroacetic Acid Salt
CAS:<p>Impurity Brimonidine EP Impurity G<br>Applications A possible metabolite of Brimonidine (B677520).<br></p>Fórmula:C11H12BrN5O·C2HF3O2Cor e Forma:NeatPeso molecular:424.17321,3,3-Trimethyl-6'-morpholinospiro[indoline-2,3'-naphtho[2,1-b][1,4]oxazine]
CAS:Pureza:97%Peso molecular:413.52099609375Ref: 10-F619849
1g446,00€5gA consultar10gA consultar2.5g959,00€50mg95,00€100mg158,00€250mg221,00€500mg366,00€Everolimus-d4 (>85%)
CAS:Produto Controlado<p>Applications Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Fórmula:C532H4H79NO14Pureza:>85%Cor e Forma:White To Light YellowPeso molecular:962.25Des(oxopentyl) Valsartan
CAS:Produto Controlado<p>Impurity Valsartan Desvaleryl Impurity<br>Applications An impurity in the synthesis of Valsartan (V095750).<br>References Carini, D., et al.: J. Med. Chem., 34, 2525 (1991), Buhlmayer, P., et al.: Bioorg. Med. Chem. Lett., 4, 29 (1994),<br></p>Fórmula:C19H21N5O2Cor e Forma:WhitePeso molecular:351.40Cyanuric Acid (1 mg/10 mL in 84:16% ACN:H2O)
CAS:Produto ControladoFórmula:C3H3N3O3Cor e Forma:Single SolutionPeso molecular:129.07Lisinopril Cyclohexyl Analogue
CAS:Produto Controlado<p>Impurity Lisinopril EP Impurity F<br>Applications Lisinopril Cyclohexyl Analogue (Lisinopril EP Impurity F) is a Lisinopril (L468985) impurity.<br>References Paraskevas, G., et al.: J. Pharm. Biomed. Anal., 29, 865 (2002),<br></p>Fórmula:C21H37N3O5Cor e Forma:NeatPeso molecular:411.541-(1,3-Dimethyl-1 H -pyrazol-4-ylmethyl)-1 H -pyrazol-4-ylamine
CAS:Fórmula:C9H13N5Pureza:97%Cor e Forma:SolidPeso molecular:191.238
![3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC366155.webp&w=3840&q=75)
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