Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4949 produtos de "Esteroides e Derivados"
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N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS:Produto Controlado<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Fórmula:C25H38N2O2Cor e Forma:NeatPeso molecular:398.58Atorvastatin Lactone Diepoxide(Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An Atorvastatin (A791750) derivative which have improved stability.<br></p>Fórmula:C33H33FN2O6Cor e Forma:NeatPeso molecular:572.62[1S-(1α,3aBeta,4β,7aAlpha)]-4-[2-(2,5-Dihydroxyphenyl)ethyl]octahydro-1-hydroxy-7a-methyl-5H-inden-5-one
CAS:Produto ControladoFórmula:C18H24O4Cor e Forma:NeatPeso molecular:304.38Prednicarbate
CAS:Produto Controlado<p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>Fórmula:C27H36O8Cor e Forma:Off-WhitePeso molecular:488.57(E/Z)-17-Deacetylnorgestimate
CAS:Produto ControladoFórmula:C21H29NO2Cor e Forma:NeatPeso molecular:327.46(11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione
CAS:Produto Controlado<p>Applications (11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione is a derivative of Dexamethasone (D298800), an anti-inflammatory glucocorticoid.<br>References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),<br></p>Fórmula:C22H27FO4Cor e Forma:WhitePeso molecular:374.453-Oxo-4-aza-5-androstene-17β-carboxylic Acid
CAS:Produto ControladoFórmula:C19H27NO3Cor e Forma:NeatPeso molecular:317.42Dexamethasone 17-Propionate
CAS:Produto Controlado<p>Applications A Dexamethasone Dipropionate metabolite.<br>References Miyachi, Y., et al.: Steroids, 52, 137 (1988), Soh H., et al.: Brit. J. dermatol., 125, 73 (1991), Civiale, C., et al.: J. Ocul. Pharmacol., Thera., 20, 75 (2004),<br></p>Fórmula:C25H33FO6Cor e Forma:NeatPeso molecular:448.5217α,21-Dideoxy-6α,9α-Difluoroprednisolone
CAS:Produto Controlado<p>Applications 17α,21-Dideoxy-6α,9α-Difluoroprednisolone is an impurity of the drug Difluprednate (D445925). Difluprednate is a corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002); Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003); Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005)<br></p>Fórmula:C20H24F2O4Cor e Forma:NeatPeso molecular:366.47-[9-[[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17β
Produto Controlado<p>Applications Fulvestrant (F862500) impurity C.<br></p>Fórmula:C41H65F5O4S2Cor e Forma:NeatPeso molecular:781.072-Hydroxy Estradiol 6-N3-Adenine
CAS:Produto Controlado<p>Applications 2-Hydroxy Estradiol 6-N3-Adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Fórmula:C23H27N5O3Cor e Forma:NeatPeso molecular:421.49δ6-Fulvestrant
CAS:Produto Controlado<p>Impurity Fulvestrant Impurity E;<br>Applications Fulvestrant (F862500) impurity E.<br></p>Fórmula:C32H45F5O3SCor e Forma:NeatPeso molecular:604.75Bexarotene-13C4
CAS:Produto Controlado<p>Applications Labelled Bexarotene (B336750). Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist.<br>References Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994), Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996), Mukherjee, R., et al.: Nature, 386, 407 (1997), Miller, V.A., et al.: J. Clin. Oncol., 15, 790 (1997)<br></p>Fórmula:C4C20H28O2Cor e Forma:NeatPeso molecular:352.45Cortisol-D4 21-Sulfate Potassium Salt
CAS:Produto Controlado<p>Applications Labelled Cortisol-d4 21-Sulfate (C696320). Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).<br>References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),<br></p>Fórmula:C21H25D4KO8SCor e Forma:NeatPeso molecular:484.64Testosterone (1mg/ml in Acetonitrile)
CAS:Produto ControladoFórmula:C19H28O2Cor e Forma:ColourlessPeso molecular:288.42Testosterone-16,16,17-d3 17-Decanoate
CAS:Produto Controlado<p>Applications Testosterone 17-Decanoate-d3, is the labeled analogue of Testosterone 17-Decanoate (T155120), an ester of Testosterone (T155000). Testosterone 17-Decanoate, can be used as a potential long-acting male contraceptive, with the combination of subcutaneous etonogestrel implants.<br>References Brady, B. M., et al.: Human Reproduction, 21 (1), 285 (2006); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000);<br></p>Fórmula:C292H3H43O3Cor e Forma:NeatPeso molecular:445.6916α-Hydroxypregna-4,9(11)-diene-3,20-dione
Produto Controlado<p>Applications 16α-Hydroxypregna-4,9(11)-diene-3,20-dione is an intermediate in the synthesis of 16-Hydroxycorticosterone 20-Hydroxy-21-Acid (H918430), an oxidized derivative of corticosterone (C695700).<br>References Allen, G.R., et al.: J. Am. Chem. Soc., 81, 4968 (1959);<br></p>Fórmula:C21H28O3Cor e Forma:NeatPeso molecular:328.45Dexamethasone 21-Palmitate
CAS:Produto Controlado<p>Applications A corticosteroid prodrug for the treatment of eye disorders.<br>References Benameur, H., et al.: J. Pharm. Pharmacol., 47, 812 (1995), Tauchi, Y., et al.: Biol. Pharm. Bull., 24, 925 (2001), Chono, S., et al.: J. Drug Targeting, 13, 407 (2005),<br></p>Fórmula:C38H59FO6Cor e Forma:NeatPeso molecular:630.8720β-Dihydrocortisone
CAS:Produto Controlado<p>Applications 20β-Dihydrocortisone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Reach, G., et. al.: Steroids, 30, 621 (1977); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)<br></p>Fórmula:C21H30O5Cor e Forma:NeatPeso molecular:362.4621-Butyryloxy Budesonide
<p>Applications 21-Butyryloxy Budesonide is a derivative of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979); Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980); Clissold, S.P., et al.: Drugs, 28, 485 (1984)<br></p>Fórmula:C29H40O7Cor e Forma:NeatPeso molecular:500.6211b-Hydroxy Etiocholanolone
CAS:Produto Controlado<p>Applications A metabolite of Etiocholanolone.<br>References Eriksson, H., et al.: Eur. J. Biochem., 15, 132 (1970), Cook, D., et al.: Endocrinology, 93, 1019 (1973),<br></p>Fórmula:C19H30O3Cor e Forma:White To Off-WhitePeso molecular:306.446β,17α-Dihydroxyprogesterone
CAS:Produto ControladoFórmula:C21H30O4Cor e Forma:NeatPeso molecular:346.4617α-Hydroxyprogesterone Heptanoate
CAS:<p>Applications 17α-Hydroxyprogesterone Heptanoate can be used in therapeutic use and biological study of pharmaceutical compounds and methods of use thereof for treating gender-biased immune disorders.<br>References Stoloff, G., et al.: PCT Int. Appl. WO 2016005599 A1 20160114 (2016)<br></p>Fórmula:C28H42O4Cor e Forma:NeatPeso molecular:442.6313-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (~90%) (Levo Norgestrel Impurity)
CAS:Produto Controlado<p>Impurity Levonorgestrel EP Impurity D<br>Applications 13-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Levonorgestrel EP Impurity D) is an impurity of Levonorgestrel.<br>References McGinty, D., et al.: Endocrinology, 24, 829 (1939), Belanger, A., et al.: Steroids, 37, 361 (1981), Nieman, L., et al.: J. Clin. Endocrinol. Metab., 61, 536 (1985), Klebe, G., et al.: J. Med. Chem., 37, 4130 (1994),<br></p>Fórmula:C21H30OCor e Forma:NeatPeso molecular:298.464-Hydroxy Estradiol 1-N3-Adenine
CAS:Produto Controlado<p>Applications 4-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H27N5O3Cor e Forma:NeatPeso molecular:421.49Epoxy Metradiene
CAS:Produto Controlado<p>Applications Epoxy Metradiene is an impurity from synthesis of Fluorometholone (F593145),a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);<br></p>Fórmula:C22H28O4Cor e Forma:NeatPeso molecular:356.4620-Dihydroprogesterone Acetate
CAS:Produto Controlado<p>Impurity Progesterone EP Impurity E<br>Applications 20-Dihydroprogesterone Acetate (Progesterone EP Impurity E) is an analogue of Progesterone (P755900), a steroid used in cardiovascular and menopausal studies.<br>References Grodstein, F. et al.: New. Eng. J. Med., 335, 453 (1996); Cushman, M. et al.: Circulation, 100, 717 (1999);<br></p>Fórmula:C23H34O3Cor e Forma:NeatPeso molecular:358.519-Chloro Triamcinolone Acetonide 21-Acetate
CAS:Produto Controlado<p>Applications Triamcinolone Acetonide (T767165) impurity.<br></p>Fórmula:C26H33ClO7Cor e Forma:WhitePeso molecular:492.9896-Deschloro Cyproterone Acetate
CAS:Produto Controlado<p>(1β,2β)-17-(Acetyloxy)-1,2-dihydro-3'H-cyclopropa[1,2]pregna<br>-1,4,6-triene-3,20-dione; 17-Hydroxy-1 ,2 -methylenepregna<br>-4,6-diene-3,20-dione Acetate; Cyproterone Acetate EP<br>Impurity A<br></p>Fórmula:C24H30O4Cor e Forma:NeatPeso molecular:382.4934'-Nitro-3'-(trifluoromethyl)acetanilide
CAS:<p>Applications 4’-Nitro-3’-(trifluoromethyl)acetanilide is a metabolite of the nonsteroidal antiandrogen drug, Flutamide (F598850).<br>References Kang, P. et al.: Drug Metab. Dispos., 36, 1425 (2008); Takashima, E. et al.: Biol. Pharmac. Bull., 26, 1455 (2003); Katchen, B. et al.: J. Invest. Dermatol., 66, 379 (1976);<br></p>Fórmula:C9H7F3N2O3Cor e Forma:NeatPeso molecular:248.16Betamethasone 21-Mesylate (>90%)
CAS:Produto ControladoFórmula:C23H31FO7SPureza:>90%Cor e Forma:NeatPeso molecular:470.55Estratetraenol
CAS:Produto Controlado<p>Applications A steroid produced by females having pheromone activities.<br>References Kotiyan, P., et al.: J. Pharm. Biomed. Anal., 22, 667 (2000), Bensafi, M., et al.: Behaviour. Brain Res., 152, 11 (2004), Zhu, B., et al.: Endocrinol., 147, 4132 (2006), Bellavance, E., et al.: J. Med. Chem., 52, 7488 (2009),<br></p>Fórmula:C18H22OCor e Forma:NeatPeso molecular:254.374-Methylestrone
CAS:Produto Controlado<p>Applications 4-Methylestrone is an intermediate in the synthesis of 4-substituted estrone and estradiol derivatives with inhibitory activities towards steroid sulfatase as a target for therapeutic intervention of treating breast cancer.<br>References Numazawa, M., et al.: J. Steroid. Biochem. Molec. Biol., 96, 51 (2005);<br></p>Fórmula:C19H24O2Cor e Forma:NeatPeso molecular:284.391,2-Dihydro-Betamethasone 17,21-Dipropionate
CAS:<p>Stability Hygroscopic<br>Applications A degradation product of Betamethasone (B327000).<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Fórmula:C28H39FO7Cor e Forma:NeatPeso molecular:506.60Dutasteride-13C6
CAS:Produto Controlado<p>Applications Labelled Dutasteride (D735000). Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Fórmula:C2113C6H30F6N2O2Cor e Forma:NeatPeso molecular:534.49(4S,trans)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:Produto ControladoFórmula:C14H27NO4Cor e Forma:NeatPeso molecular:273.376-Keto Dexamethasone
Produto Controlado<p>Applications 6-keto Dexamethasone, is an impurity of Dexamethasone, a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br></p>Fórmula:C22H27FO6Cor e Forma:NeatPeso molecular:406.44Travoprost 13,14-Epoxide (Mixture of Diastereomers)
Produto Controlado<p>Stability Temperature Sensitive<br>Applications An epoxy impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600).<br></p>Fórmula:C26H35F3O7Cor e Forma:NeatPeso molecular:516.35Fluticasone-d3 17β-Carboxylic Acid
CAS:Produto ControladoFórmula:C21H23D3F2O5Cor e Forma:NeatPeso molecular:399.44(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
CAS:Produto Controlado<p>Applications Glucocorticoid.<br></p>Fórmula:C22H28O4Cor e Forma:NeatPeso molecular:356.46Prednisolone 21-Sulfate Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Prednisolone 21-Sulfate is a metabolite of Prednisolone (P703740).<br>References Hutzler, J., ET AL.: Drug Metab. Dispos., 30, 355 (2002), Sugiyama, D., et al.: J. Biol. Chem., 278, 43489 (2003), Hagenbuch, B., et al.: Xenobiotica, 38, 778 (2008),<br></p>Fórmula:C21H27NaO8SCor e Forma:NeatPeso molecular:462.496α-Hydroxy Testosterone-d3
CAS:Produto ControladoFórmula:C19H25D3O3Cor e Forma:NeatPeso molecular:307.443β-Hydroxy Tibolone (1mg/ml in Acetonitrile)
CAS:Produto ControladoFórmula:C21H30O2Cor e Forma:Single SolutionPeso molecular:314.46δ6-Gestodene
Produto Controlado<p>Applications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.<br>References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);<br></p>Fórmula:C21H24O2Cor e Forma:NeatPeso molecular:308.413-Aminobenzotrifluoride
CAS:Produto Controlado<p>Applications 3-Aminobenzotrifluoride is a known human toxin that can cause bacterial mutation and hepatocyte unscheduled DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reinhold, D., et al.: T. ASAE, 49, 2077 (2006); Thompson, C., et al.: Environ. Mutagen., 5, 803 (1983)<br></p>Fórmula:C7H6F3NCor e Forma:YellowPeso molecular:161.126b-Methyl Fluorometholone
CAS:Produto Controlado<p>Stability Not stable in Acidic or basic condition<br>Applications 6β-Methyl Fluorometholone is an impurity in the synthesis of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Fórmula:C22H29FO4Cor e Forma:NeatPeso molecular:376.463-O-Benzyl Estriol
CAS:Produto Controlado<p>Applications Protected Estriol.<br>References Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Fórmula:C25H30O3Cor e Forma:NeatPeso molecular:378.507α-Acetylthio-17α-ethoxymethyl Testosterone
CAS:Produto ControladoFórmula:C24H36O4SCor e Forma:NeatPeso molecular:420.616a-9-Difluoroprednisolone-17-Carboxylate
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 6α-9-Difluoroprednisolone-17-Carboxylate is an impurity of 6α,9α-Difluoroprednisolone (D446290), shown to increase metastases and increase glucocorticoid activity in C57/BL6 mice.<br>References Albert, D., Zeidman, I.: Cancer Res., 22, 1297 (1962)<br></p>Fórmula:C20H24F2O5Cor e Forma:NeatPeso molecular:382.4Fluocinolone Acetonide-13C3
CAS:Produto ControladoFórmula:C2113C3H30F2O6Cor e Forma:NeatPeso molecular:455.47Tetrahydrocortisol 21-Acetate
CAS:Produto Controlado<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Fórmula:C23H36O6Cor e Forma:NeatPeso molecular:408.53(11β,16β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione(Deflazacort Impurity)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications (11β,16β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, is an impurity of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus.<br>References Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),<br></p>Fórmula:C27H33NO7Cor e Forma:NeatPeso molecular:483.55(5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one
CAS:Produto Controlado<p>Applications (5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one is metabolite and impurity of the anabolic steroid Oxandrolone (O845050).<br>References Fragkaki, A.G. et al.: J. Steroid Biochem. Mol. Biol., 115, 44 (2009); Bi, H. et al.: J. Steroid Biochem. Mol. Biol., 42, 533 (1992);<br></p>Fórmula:C19H28O2Cor e Forma:White To Off-WhitePeso molecular:288.4217β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
CAS:Produto Controlado<p>Applications 17β-Hydroxy Exemestane 17-O-β-D-Glucuronide is the glucuronidated conjugate of the hydroxy metabolite of Exemestane (E957000).<br>References Sun, D. et al.: Pharmacogen. Genom., 20, 575 (2010);<br></p>Fórmula:C26H31D3O8Cor e Forma:NeatPeso molecular:477.5610b-Hydroxy D-(-)-Norgestrel
CAS:<p>Applications 10β-Hydroxy D-(-)-Norgestrel is an impurity of Levonorgestrel (N689510).<br>References Gorog, S. et al.: J. Pharmac. Biomed. Anal., 14, 85 (1995); Berta, R. et al.: J. Pharmac. Biomed. Anal., 54, 458 (2011); Choudhary, M. I. et al.: Nat. Prod. Res., 20, 1074 (2006);<br></p>Fórmula:C21H28O3Cor e Forma:White To Off-WhitePeso molecular:328.44517α-Methyl-4-[(phenylthio)methyl]testosterone
CAS:Produto Controlado<p>Applications Testosterone (T155000) derivative.<br></p>Fórmula:C27H36O2SCor e Forma:NeatPeso molecular:424.647-(Desacetothioxy)-7-acetodithioperoxy-spironolactone
Produto ControladoFórmula:C24H32O4S2Cor e Forma:NeatPeso molecular:448.64(16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
CAS:Produto Controlado<p>Applications (16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)<br></p>Fórmula:C25H32O6Cor e Forma:NeatPeso molecular:428.526b-Chloro-17-acetoxy Progesterone
CAS:Produto Controlado<p>Applications Progesterone (P755900) impurity.<br>References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),<br></p>Fórmula:C23H31ClO4Cor e Forma:NeatPeso molecular:406.943Des[[N-(1,1-Dimethylethyl)amino]carbonyl] 17-(Propionyl) Finasteride
CAS:Produto Controlado<p>Applications An impurity of Finasteride (F342000).<br></p>Fórmula:C21H31NO2Cor e Forma:NeatPeso molecular:329.483β,5α-Tetrahydrodeoxycorticosterone
CAS:<p>Applications 3β,5α-Tetrahydrodeoxycorticosterone is a novel derivative of the steroid Dehydroepiandrosterone (DHEA), a known uncompetitive inhibitor of Glucose 6-Phosphate Dehydrogenase (G6PD). Studies have shown that 3β,5α-Tetrahydrodeoxycorticosterone may have potential function in the modulation of calcium and GABAA-gated chloride channel currents found in rat and guinea-pig neurons.<br>References Hamilton, N.M., et al.: J. Medn. Chem., 55, 4431 (2012); Ffench, M., et al.: Steriods., 64, 76 (1999);<br></p>Fórmula:C21H34O3Cor e Forma:White To Off-WhitePeso molecular:334.4918-Methyl Mestranol
CAS:Produto Controlado<p>Applications Mestranol (M258755) derivative. It is used as contraceptive.<br>References Cullen, L.F., et al.: J. Pharma. Sci., 57, 1857 (1968),<br></p>Fórmula:C22H28O2Cor e Forma:NeatPeso molecular:324.466α-Hydroxy Gestrinone Glucuronide
CAS:Produto ControladoFórmula:C27H32O9Cor e Forma:Light YellowPeso molecular:500.54Desogestrel
CAS:Produto Controlado<p>Applications A progestogen with low androgenic potency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Fórmula:C22H30OCor e Forma:White To Off-WhitePeso molecular:310.474β-Hydroxy Cholesterol
CAS:Produto Controlado<p>Applications A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>Fórmula:C27H46O2Cor e Forma:White To Light BeigePeso molecular:402.65Desisobutyryl Ciclesonide
CAS:Produto Controlado<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Fórmula:C28H38O6Cor e Forma:White To Off-WhitePeso molecular:470.602-Hydroxy-estrone-6-N3-adenine (90%)
CAS:Produto Controlado<p>Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Fórmula:C23H25N5O3Pureza:90%Cor e Forma:NeatPeso molecular:419.4817β-Dihydro Equilin-16,16,17-d3
CAS:Produto Controlado<p>Applications A labelled metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C182H3H17O2Cor e Forma:NeatPeso molecular:271.37Digitoxigenin Mono-β-D-digitoxoside
CAS:Produto ControladoFórmula:C29H44O7Cor e Forma:White To Off-WhitePeso molecular:504.6618-Methyl Ethynyl Estradiol
CAS:Produto ControladoFórmula:C21H26O2Cor e Forma:NeatPeso molecular:310.4299Dexamethasone Phosphate Bisulfate Adduct Sodium Salt
CAS:Fórmula:C22H32FO11PS•xNaCor e Forma:NeatPeso molecular:554.5222986β-Hydroxymethylandrosta-1,4-diene-3,17-dione
CAS:Produto ControladoFórmula:C20H26O3Cor e Forma:White To Off-WhitePeso molecular:314.42Betamethasone 21-Phosphate Biotin (>85%)
Produto ControladoFórmula:C34H49FN3O10PSPureza:>85%Cor e Forma:NeatPeso molecular:741.8115-Keto Latanoprost
CAS:<p>Applications 15-Keto Latanoprost is a metabolite of Latanoprost (L177280).<br>References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999),<br></p>Fórmula:C23H30O5Cor e Forma:NeatPeso molecular:386.482,2-Dibromo-1-(4-fluorophenyl)-2-phenylethanone
Produto ControladoFórmula:C14H9Br2FOCor e Forma:NeatPeso molecular:372.036-Oxo Boldione
CAS:Produto Controlado<p>Applications A derivative of Exemestane (E957000), a new aromatase inhibitor.<br>References Thompson, E., et al.: J. Biol. Chem., 249, 5364 (1974), Cole, P., et al.: J. Med. Chem., 33, 2933 (1990), Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Fórmula:C19H22O3Cor e Forma:Off-White To Light YellowPeso molecular:298.382-Hydroxy Atorvastatin Lactone
CAS:Produto Controlado<p>Impurity Atorvastatin 2-Hydroxy Lactone<br>Stability Hygroscopic<br>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br></p>Fórmula:C33H33FN2O5Cor e Forma:Off White SolidPeso molecular:556.62D-Homoanalog of Triamcinolone
CAS:Produto Controlado<p>Applications D-Homoanalog of Triamcinolone is a rearrangement product of the drug triamcinolone, an anti-inflammatory drug.<br>References Delaney, E. J.; et al.: Steroids, 59, 196 (1994)<br></p>Fórmula:C21H27FO6Cor e Forma:NeatPeso molecular:394.43Fluticasone furoate EP impurity G
CAS:<p>Fluticasone furoate is a synthetic corticosteroid that has anti-inflammatory and immunosuppressive properties. It binds to the glucocorticoid receptor, which inhibits the production of inflammatory cytokines and mediators. The impurity standard used in this product is Fluticasone furoate EP impurity G. This impurity is a metabolite of fluticasone furoate with a molecular weight of 488. It has been shown that this impurity may have an effect on the pharmacokinetics of fluticasone furoate.</p>Fórmula:C27H29ClF2O6SPureza:Min. 95%Peso molecular:555.03 g/molDexamethasone-17-ketone
CAS:Produto Controlado<p>Please enquire for more information about Dexamethasone-17-ketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C20H25FO3Pureza:Min. 95%Peso molecular:332.42 g/molDexamethasone EP Impurity K
CAS:Produto Controlado<p>Dexamethasone EP Impurity K is an analytical standard for impurities in the drug product Dexamethasone EP. It is a synthetic methanolic solution of dexamethasone and a metabolite, which is chemically identical to the natural form. The purity of this impurity standard is 99.9%. This synthetic impurity is used for HPLC analysis as a pharmacopoeia-grade reference material.</p>Fórmula:C22H26O4Pureza:Min. 95%Peso molecular:354.44 g/mol(5E)-Calcipotriene
CAS:<p>(5E)-Calcipotriene is a synthetic, natural, and analytical chemical. It is a white to off-white powder with a melting point of about 122 °C. (5E)-Calcipotriene has been used as an analytical standard for HPLC and as an impurity in the synthesis of calcitriol. The International Union of Pure and Applied Chemistry (IUPAC) name for this compound is 5Z,7Z,11Z,15Z-eicosapentaenoic acid. It can also be found in the form of 5Z,8Z,11Z,14E-eicosapentaenoic acid.</p>Fórmula:C27H40O3Pureza:Min. 95%Peso molecular:412.6 g/molFluticasone Impurity D
CAS:<p>Fluticasone Impurity D is a sulfoxide that is found in the drug fluticasone. It is a conjugate of fatty acid and fatty alcohol, which are esters of irritants. Fluticasone Impurity D is an experimental model for inflammatory diseases. It can be used as a pharmaceutical dosage to enhance the effects of other drugs by increasing their absorption through the skin. The effects of this drug have been tested on tissues and experimental models, but not on humans.</p>Pureza:Min. 95%Atorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt
CAS:<p>Atorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt is a synthetic drug product that belongs to the class of statins. It has been used in research and development as a standard for HPLC analysis. The metabolite atorvastatin 3,5-dihydroxy-7-heptanoic acid (CAS No. 1105067-87-5) is also available from Sigma Aldrich. The impurity standards atorvastatin calcium salt and amorphous calcium sulfate are also available from Sigma Aldrich. Atorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt is an API impurity in the synthesis of atorvastatin sodium (CAS No. 120781-93-1).</p>Fórmula:C40H48FN3O8CaPureza:Min. 95%Peso molecular:737.86 g/mol(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt
CAS:<p>(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt is an impurity standard for the drug product. It is a synthetic metabolite that binds to proteins and has been found in human urine. The chemical synthesis of (3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6 heptenoic acid sodium salt was performed using a high purity custom synthesis and high purity pharmacopoeia grade reagents.</p>Fórmula:C23H23FNNaO4Pureza:Min. 95%Peso molecular:419.42 g/molFluticasone furoate EP impurity E
CAS:<p>Fluticasone furoate EP impurity E is an analytical reference standard for pharmacopoeia and research. It is a synthetic fluticasone furoate EP impurity that has been custom synthesized for use as a high-purity, HPLC-grade standard. Fluticasone furoate EP impurity E is characterized by its natural origin and purity, making it appropriate for use in drug development and research. The CAS number for this product is 398454-97-2.</p>Fórmula:C25H31F3O5SPureza:Min. 95%Peso molecular:500.5 g/molrac 5-Keto Fluvastatin
CAS:<p>Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.</p>Fórmula:C24H24FNO4Pureza:Min. 95%Cor e Forma:Yellow PowderPeso molecular:409.45 g/mol(3S,5R)-Atorvastatin calcium
CAS:<p>(3S,5R)-Atorvastatin calcium is an analytical standard for the drug atorvastatin. It has a purity of 99.9% and is manufactured in accordance with the requirements of the pharmacopoeia. The product is available as a white crystalline powder and is soluble in water, acetone, and ethanol. (3S,5R)-Atorvastatin calcium has been used in drug development and as an impurity standard for HPLC analysis. It also serves as a metabolite to characterize the production process of atorvastatin.</p>Fórmula:C66H68CaF2N4O10Pureza:Min. 95%Peso molecular:1,155.34 g/molFluorometholone δ 9,11
CAS:Produto Controlado<p>Fluorometholone delta 9,11 is a drug product that is used as an analytical reference standard for the quantitative determination of impurities in drugs. It is a natural metabolite and impurity in synthetic drugs such as fluoroquinolones and corticosteroids. Fluorometholone delta 9,11 has been shown to be a substrate for CYP3A4 and P-glycoprotein. This drug has also been shown to have anti-inflammatory effects and may decrease the risk of infection by suppressing neutrophil function.</p>Fórmula:C22H28O3Pureza:Min. 95%Peso molecular:340.46 g/molAtorvastatinN-(3,5-dihydroxy-7-heptanoic acid)amide
CAS:<p>Atorvastatin is a synthetic drug product. It is a prodrug that is converted to its active form, atorvastatin acid, in the body. Atorvastatin is used for lowering blood cholesterol levels in people with hypercholesterolemia and reducing the risk of coronary heart disease. This drug has been shown to reduce the number of deaths from coronary heart disease by 30% after five years of use. Atorvastatin also reduces the risk of stroke and fatal or non-fatal heart attack by 20%.</p>Fórmula:C40H48FN3O8Pureza:Min. 95%Peso molecular:717.82 g/mol
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