Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4948 produtos de "Esteroides e Derivados"
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1,2-Dihydro Triamcinolone
CAS:Produto Controlado<p>Applications 1,2-Dihydro Triamcinolone is a derivative of Triamcinolone (T767165), a glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal).<br>References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972); Bernstein, I.L., et al.: Chest, 81, 20 (1982);<br></p>Fórmula:C21H29FO6Cor e Forma:NeatPeso molecular:396.4513β-Ethyl-11-methylenegon-4-en-17-one
CAS:Produto Controlado<p>Applications Desogestrel intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bergink, E., et al.: J. Steroid Biochem., 14, 175 (1981), Phillips, A., et al.: Contraception, 36, 181 (1987)<br></p>Fórmula:C20H28OCor e Forma:NeatPeso molecular:284.44Atorvastatin-d5 tert-Butyl Ester
CAS:Produto Controlado<p>Applications Atorvastatin-d5 tert-Butyl Ester is the labeled analogue of Atorvastatin tert-Butyl Ester (A791740), an impurity arising in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C37H38D5FN2O5Cor e Forma:NeatPeso molecular:619.78Atorvastatin Lactone Diepoxide(Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An Atorvastatin (A791750) derivative which have improved stability.<br></p>Fórmula:C33H33FN2O6Cor e Forma:NeatPeso molecular:572.62Desogestrel
CAS:Produto Controlado<p>Applications A progestogen with low androgenic potency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Fórmula:C22H30OCor e Forma:White To Off-WhitePeso molecular:310.47Tixocortol
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.<br>References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),<br></p>Fórmula:C21H30O4SCor e Forma:NeatPeso molecular:378.532,5-Bis(trifluoromethyl)aniline
CAS:Produto Controlado<p>Applications 2,5-Bis(trifluoromethyl)aniline is a haloalkul substituted aniline used in the preparation of anti-benign prostatic hyperplasia drug, Dutasteride (D735000).<br>References Liang, Y. et al.: Jil. Dax. Xueb. Lixeub., 45, 1035 (2007);<br></p>Fórmula:C8H5F6NCor e Forma:ColourlessPeso molecular:229.126-Keto Dexamethasone
Produto Controlado<p>Applications 6-keto Dexamethasone, is an impurity of Dexamethasone, a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br></p>Fórmula:C22H27FO6Cor e Forma:NeatPeso molecular:406.44Tetrahydrocortisol 21-Acetate
CAS:Produto Controlado<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Fórmula:C23H36O6Cor e Forma:NeatPeso molecular:408.53Testosterone-16,16,17-d3 17-Decanoate
CAS:Produto Controlado<p>Applications Testosterone 17-Decanoate-d3, is the labeled analogue of Testosterone 17-Decanoate (T155120), an ester of Testosterone (T155000). Testosterone 17-Decanoate, can be used as a potential long-acting male contraceptive, with the combination of subcutaneous etonogestrel implants.<br>References Brady, B. M., et al.: Human Reproduction, 21 (1), 285 (2006); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000);<br></p>Fórmula:C292H3H43O3Cor e Forma:NeatPeso molecular:445.69Betamethasone 17-Propionate 21-Mesylate
CAS:<p>Impurity Clobetasol Propionate EP Impurity I<br>Stability Hygroscopic<br>Applications Betamethasone 17-Propionate 21-Mesylate (Clobetasol Propionate EP Impurity I) is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.<br>References Mitsukuchi, M. et al.: Chem. Pharm. Bull., 37, 3286 (1989);<br></p>Fórmula:C26H35FO8SCor e Forma:NeatPeso molecular:526.61(6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:Produto Controlado<p>Applications (6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione is an intermediate in the synthesis of Paramethasone Acetate (P191845), a derivative of Dexamethasone (D298800), a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant properties.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C24H29FO6Cor e Forma:Off-WhitePeso molecular:432.489-Dehydroestrone
CAS:Produto ControladoFórmula:C18H20O2Cor e Forma:White To Off-WhitePeso molecular:268.35Mexrenone
CAS:Produto Controlado<p>Applications Mexrenone is an impurity of eplerenon (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Fórmula:C24H32O5Cor e Forma:Off-WhitePeso molecular:400.50796-Deschloro Cyproterone Acetate
CAS:Produto Controlado<p>(1β,2β)-17-(Acetyloxy)-1,2-dihydro-3'H-cyclopropa[1,2]pregna<br>-1,4,6-triene-3,20-dione; 17-Hydroxy-1 ,2 -methylenepregna<br>-4,6-diene-3,20-dione Acetate; Cyproterone Acetate EP<br>Impurity A<br></p>Fórmula:C24H30O4Cor e Forma:NeatPeso molecular:382.493(3(α))-Allopregnanolone 3-(β)-DGlucuronide
CAS:Produto Controlado<p>Applications (3α)-Allopregnanolone 3-β-D-Glucuronide is the glucuronide conjugate of (3α)-Allopregnanolone (A547100), metabolite of progesterone and potent positive modulator of GABAA receptors.<br>References Martin, F. et al.: LJ Steroid Biochem., 6, 1339 (1975); Lin, M.T. et al.: Steroids, 32, 547 (1978);<br></p>Fórmula:C27H42O8Cor e Forma:NeatPeso molecular:494.622-Hydroxy-estrone-6-N3-adenine (90%)
CAS:Produto Controlado<p>Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Fórmula:C23H25N5O3Pureza:90%Cor e Forma:NeatPeso molecular:419.484-Methylestrone
CAS:Produto Controlado<p>Applications 4-Methylestrone is an intermediate in the synthesis of 4-substituted estrone and estradiol derivatives with inhibitory activities towards steroid sulfatase as a target for therapeutic intervention of treating breast cancer.<br>References Numazawa, M., et al.: J. Steroid. Biochem. Molec. Biol., 96, 51 (2005);<br></p>Fórmula:C19H24O2Cor e Forma:NeatPeso molecular:284.39
