Fosfatos e Fosfonatos Orgânicos
Os fosfatos orgânicos são compostos que contêm um grupo fosfato (-PO₄) ligado a um átomo de carbono numa estrutura orgânica, geralmente em combinação com álcoois, ácidos ou aminas. Estes compostos são utilizados na formulação de APIs para melhorar a solubilidade, estabilidade e biodisponibilidade dos princípios ativos. Os fosfatos orgânicos também desempenham um papel na liberação controlada de fármacos e na melhoria da absorção de certos medicamentos.
Os fosfonatos orgânicos contêm um grupo fosfonato (-PO₃H₂), no qual o átomo de fósforo está ligado a um átomo de carbono e a dois grupos oxigênio. Estes compostos possuem propriedades farmacológicas importantes, especialmente na inibição de enzimas e na modulação de processos bioquímicos. Os fosfonatos orgânicos são utilizados na produção de APIs que atuam no metabolismo ósseo, no tratamento de infecções bacterianas ou como antivirais, devido aos seus efeitos biológicos específicos.
Na CymitQuimica, oferecemos fosfatos e fosfonatos orgânicos para pesquisa em química médica, bioquímica e desenvolvimento de formulações avançadas.
Foram encontrados 1201 produtos de "Fosfatos e Fosfonatos Orgânicos"
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Deferasirox Ethyl Ester
CAS:Produto Controlado<p>Applications Deferasirox Ethyl Ester is a derivative of Deferasirox (D228650); an orally active tridentate iron chelator.<br>References Hershko, C., et al.: Blood, 97, 1115 (2001); Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003); Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003)<br></p>Fórmula:C23H19N3O4Cor e Forma:White To Light YellowPeso molecular:401.41POPE
CAS:Produto Controlado<p>Stability Light Sensitive, Moisture Sensitive<br>Applications POPE is a component of E. Coli bacteria cell membrane.<br>References Tu, Y., et al.: Nature Nanotechnology, 8, 594 (2013).<br></p>Fórmula:C39H76NO8PCor e Forma:NeatPeso molecular:718.0Sodium ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogenphosphate
CAS:Pureza:98.0%Peso molecular:346.164001464843752-(2,4,5-Trichlorophenoxy)propionic Acid
CAS:Produto ControladoFórmula:C9H7Cl3O3Cor e Forma:NeatPeso molecular:269.514-Hydroperoxy Cyclophosphamide
CAS:Produto ControladoFórmula:C7H15Cl2N2O4PCor e Forma:NeatPeso molecular:293.083-(2-Chloroethyl)octahydro-2-hydroxy-1,3,6,2-oxadiazaphosphonine 2-Oxide
CAS:Produto Controlado<p>Impurity Cyclophosphamide Impurity B<br>Stability Hygroscopic<br>Applications A metabolite of Cyclophosphamide (C988580). Cyclophosphamide Impurity B<br>References Joqueviel, C. et al.: Drug Metab. Dispos., 26, 418 (1998);<br></p>Fórmula:C7H16ClN2O3PCor e Forma:NeatPeso molecular:242.643-(Methylnitrosamino)propanal
CAS:Produto Controlado<p>Applications 3-(Methylnitrosamine)propionaldehyde (MNPA) was detected for the 1st time in the saliva of betel quid chewers and is a potent carcinogen. It exhibits higher cytotoxicity than Nitrosoguvacine (NGC), Nitrosoguvacoline (NG) and 3-(Methylnitrosamino)propionitrile (MNPN).<br>References Bartsch, H., et al.: Mutat. Res., 250, 103 (1991), Su, T., et al.: Drug Metab. Dispos., 24, 884 (1996), Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001),<br></p>Fórmula:C4H8N2O2Cor e Forma:NeatPeso molecular:116.12(Z)-Tetrachlorvinphos
CAS:Produto Controlado<p>Applications (Z)-Tetrachlorvinphos is used in sensitive immunoassay for detection of organophosphorus pesticides. Also, used in exposure characterization of varied major insecticides including neonicotinoids, organophosphates and pyrethroids in urine of young children. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhao, F., et al.: Anal. Bioanal. Chem., 408, 6423 (2016); Osaka, A., et al.: Environ. Res., 147, 89 (2016)<br></p>Fórmula:C10H9Cl4O4PCor e Forma:Off-WhitePeso molecular:365.96(2,7-di-tert-Butyl-9-methyl-9H-fluoren-9-yl)phosphonic acid
CAS:Pureza:98%Peso molecular:372.44500732421875Glufosinate Ammonium
CAS:<p>Stability Hygroscopic<br>Applications Used as a herbicide.<br>References Abbas, H., et al.: J. Agric. Food Chem., 50, 5246<br></p>Fórmula:C5H11NO4P·H4NCor e Forma:White To BeigePeso molecular:198.163-(Methylnitrosamino)propionitrile
CAS:Produto Controlado<p>Applications 3-(Methylnitrosamino)propionitrile (MNPN) was detected for the 1st time in the saliva of betel quid chewers and is a potent carcinogen.<br>References Bartsch, H., et al.: Mutat. Res., 250, 103 (1991), Su, T., et al.: Drug Metab. Dispos., 24, 884 (1996), Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001),<br></p>Fórmula:C4H7N3OCor e Forma:Light YellowPeso molecular:113.12Triisopropyl Phosphate
CAS:Produto Controlado<p>Applications Triisopropyl Phosphate can be used as a flame retardant and catalyst.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, Tie-jiang.: Meitan Jishu,29(2), 204-206 (2010);Chen, Yong-Fu, et al.: Jingxi Huagong, 17(9), 541-543 (2000)<br></p>Fórmula:C9H21O4PCor e Forma:NeatPeso molecular:224.23Risedronic Acid-d4 (Major)
CAS:Produto ControladoFórmula:C7H7D4NO7P2Cor e Forma:NeatPeso molecular:287.14Uridine-3'-monophosphate disodium salt
CAS:Pureza:99.0%Cor e Forma:SolidPeso molecular:368.1449890136719Sodium (3-amino-1-hydroxy-1-phosphonopropyl)phosphonate xhydrate
CAS:Pureza:95.0%Cor e Forma:Solid, No data available.Peso molecular:297.0469970703125Ref: 10-F431320
1gA consultar5gA consultar10gA consultar25gA consultar50mgA consultar250mgA consultarN-Acetyl Glufosinate Sodium
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications The major metabolite of herbicidal Glufosinate (G596950).<br></p>Fórmula:C7H12NNa2O5PCor e Forma:White To Off-WhitePeso molecular:267.13Disalicylimide
CAS:<p>Applications Disalicylimide is an impurity of Deferasirox (D228650), an orally active tridentate iron chelator.<br>References Hershko, C., et al.: Blood, 97, 1115 (2001), Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003), Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003),<br></p>Fórmula:C14H11NO4Cor e Forma:NeatPeso molecular:257.25Parathion-methyl-d6
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Isotope labelled Parathion-methyl is an derivative of Parathion (P192220), an organophosphate insecticide used on cotton, rice and fruit trees. Cannabis testing.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sykes, M., et al.: J. Agri. Food. Chem., 61, 4205 (2013); Sipes, N.S., et al.: Chem. Res. Toxicol., 26, 878 (2013);<br></p>Fórmula:C82H6H4NO5PSCor e Forma:Colourless To Off-WhitePeso molecular:269.24Alendronic Acid-d6 (Major)
CAS:Produto ControladoFórmula:C4D6H7NO7P2Cor e Forma:NeatPeso molecular:255.13Metaraminol Bitartrate
CAS:Produto Controlado<p>Applications Metaraminol Bitartrate is a vasopressor comparable to ephedrine used in the maintenance of arterial pressure during spinal anesthesia. Also used in the treatment of hypotension while under the effect of anaesthesia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ngan, K. et al.: Anesthes., 95, 307 (2001); Critchley, L. et al.: Br. J. Anaesth., 76, 734 (1996);<br></p>Fórmula:C9H13NO2·C4H6O6Cor e Forma:WhitePeso molecular:317.29Bis(2-chloroethyl)amine Hydrochloride
CAS:Produto Controlado<p>Impurity Cyclophosphamide Impurity A<br>Applications A cytotoxic metabolite of Cyclophosphamide; a deuterated analog of Nor-nitrogen mustard. Cyclophosphamide Impurity A<br>References Colvin, M. et al.: Cancer Res., 36, 1121 (1976); Ludeman, S. et al.: Drug Metab Dispos., 20, 337 (1992); Ludeman, S.M. et al.: J. Pharmaceut. Sci., 84, 393 (1995); Yu, L. et al.: Drug Metab. Dispos., 24, 1254 (1996);<br></p>Fórmula:C4H9Cl2N·ClHCor e Forma:White To Light YellowPeso molecular:178.49Phoxim
CAS:<p>Stability Moisture Sensitive<br>Applications Phoxim is an organophosphate insecticide. It is an analogous dimethyl ester and an organothiophosphate acaricide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lu, Y., et al.: Nature, 487, 362 (2012); Jokanovic, M., et al.: Arch. Toxicol., 70, 119 (1995); Wang, W., et al.: Pest. Biochem. Physiol., 84, 180 (2006)<br></p>Fórmula:C12H15N2O3PSCor e Forma:Light Yellow To YellowPeso molecular:298.30Pravastatin lactone
CAS:<p>Pravastatin lactone is a prodrug of pravastatin that is hydrolyzed in vivo to its active form. It is used for the treatment of bowel disease and has been shown to have concentration-time curves that are linear and dose-dependent. Pravastatin lactone has an acidic pH, which may be due to the presence of carboxyl groups on the molecule. This drug also inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, which is an enzyme that catalyzes the conversion of HMG CoA to mevalonate in order to produce cholesterol. Pravastatin lactone also suppresses the production of fatty acids by inhibiting their synthesis at the level of acetyl-coenzyme A (acetyl-CoA). The drug has not shown any evidence of toxicity when administered to rats at doses up to 10 mg/kg body weight per day</p>Fórmula:C23H34O6Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:406.51 g/mol6-Epi pravastatin sodium
CAS:<p>6-Epi pravastatin sodium salt is a synthetic compound with the same molecular formula and chemical structure as the natural product. It has been used in pharmacological studies, drug development, and research. 6-Epi pravastatin sodium salt is a metabolite of pravastatin.</p>Fórmula:C23H36O7•NaPureza:Min. 92.0 Area-%Peso molecular:447.51 g/mol5′-Uridylic acid disodium salt
CAS:Fórmula:C9H11N2Na2O9PPureza:95%Cor e Forma:SolidPeso molecular:368.145Nitrilotris(methylenephosphonic acid) (ca. 50% in water, ca. 2.2mol/L)
CAS:Fórmula:C3H12NO9P3Pureza:95.0%Cor e Forma:Liquid, Clear colourless to slightly pale yellow liquidPeso molecular:299.048L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-phosphono-
CAS:Pureza:97%Peso molecular:483.4129944(S)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid
CAS:Fórmula:C9H14N5O4PPureza:98%Peso molecular:287.216N-(CARBOXYMETHYL)-N-(PHOSPHONOMETHYL)-GLYCINE
CAS:Pureza:97%Cor e Forma:SolidPeso molecular:227.1089935((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid
CAS:Fórmula:C8H12N5O4PPureza:95%Cor e Forma:SolidPeso molecular:273.189disodium hydrate [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-3H-purin-9-yl)oxolan-2-yl]methyl phosphate
CAS:Pureza:98%Peso molecular:410.1860046(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(difluoro(phosphono)methyl)phenyl)propanoic acid
CAS:Pureza:98%Peso molecular:517.4219971Alendronic Acid
CAS:<p>Alendronic Acid (alendronate) is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.</p>Fórmula:C4H13NO7P2Pureza:99.89% - ≥95%Cor e Forma:White Crystalline PowderPeso molecular:249.1Calcium 2-(trimethylammonio)ethyl phosphate chloride tetrahydrate
CAS:Fórmula:C5H21CaClNO8PPureza:98%Cor e Forma:SolidPeso molecular:329.723-Aminopropylphosphonic acid
CAS:Fórmula:C3H10NO3PPureza:95%Cor e Forma:Solid, White to light yellow solidPeso molecular:139.091Phosphoenolpyruvate, monocyclohexylammonium salt
CAS:<p>M02737 - Phosphoenolpyruvate, monocyclohexylammonium salt</p>Fórmula:C9H18NO6PPureza:95%Cor e Forma:White to off-white crystalline powderPeso molecular:267.218disodium hydrate [(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
CAS:Pureza:97%Peso molecular:425.2009888Disodium 1-naphthyl phosphate hydrate
CAS:Fórmula:C10H9Na2O5PPureza:95%Cor e Forma:LiquidPeso molecular:286.13Adenosine-5′-monophosphate monohydrate
CAS:Fórmula:C10H16N5O8PPureza:98%Cor e Forma:SolidPeso molecular:365.239Sodium (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl hydrogenphosphate dihydrate
CAS:Pureza:60%Peso molecular:514.3599854Sodium ((2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate
CAS:Pureza:98%Peso molecular:351.1624-Nitrophenyl phosphate disodium salt hexahydrate
CAS:Fórmula:C6H16NNa2O12PPureza:97%Cor e Forma:Solid, Off-white to yellow crystalline powderPeso molecular:371.1422′-Deoxythymidine-5′-monophosphate disodium salt
CAS:Fórmula:C10H13N2Na2O8PPureza:98%Cor e Forma:Solid, White powderPeso molecular:366.173Sodium Phosphate Dibasic
CAS:<p>Applications Sodium Phosphate Dibasic is used as an in conjunction with trisodium phosphate in foods and water treatment. In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. Sodium Phosphate Dibasic is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.<br>References Tsioulpas, A., et al.: Food Chem., 122, 1027 (2010); Schrödter, K., et al.: Ullmann’s Encyclopedia of Industrial Chemistry (2008); Hansen, C., et al.: Am. J. Obstet. Gynecol., 196, 311 (2007)<br></p>Fórmula:Na·HO4PCor e Forma:NeatPeso molecular:141.96Pravastatin
CAS:<p>Pravastatin reduces lipoproteins by blocking HMG-CoA reductase and VLDL synthesis.</p>Fórmula:C23H36O7Pureza:98%Cor e Forma:White PowderPeso molecular:424.532-(phosphonooxy)benzoic acid
CAS:Fórmula:C7H7O6PPureza:≥97%Cor e Forma:No data available.Peso molecular:218.101(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonic acid monohydrate
CAS:Fórmula:C5H12N2O8P2Pureza:98%Cor e Forma:White – Very pale yellow powderPeso molecular:290.105Potassium hexadecyl hydrogenphosphate
CAS:Fórmula:C16H34KO4PPureza:95.0%Cor e Forma:SolidPeso molecular:360.516(2-Amino-2,3-dihydro-1H-inden-2-yl)phosphonic acid hydrochloride
CAS:Fórmula:C9H13ClNO3PPureza:97%Cor e Forma:SolidPeso molecular:249.63Phosphoenolpyruvate, monopotassium salt
CAS:<p>M02738 - Phosphoenolpyruvate, monopotassium salt</p>Fórmula:C3H4KO6PPureza:96%Cor e Forma:Solid, PowderPeso molecular:206.131[2,2′-Bipyridine]-4,4′-diyldiphosphonic acid
CAS:Fórmula:C10H10N2O6P2Pureza:97%Cor e Forma:SolidPeso molecular:316.146(1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-diyl)diphosphonic acid
CAS:Fórmula:C9H12N2O7P2Pureza:95%Cor e Forma:SolidPeso molecular:322.155-Bromo-4-chloro-3-indolyl phosphate, disodium salt
CAS:<p>M02703 - 5-Bromo-4-chloro-3-indolyl phosphate, disodium salt</p>Fórmula:C8H4BrClNNa2O4PPureza:97%Cor e Forma:Solid, Light grey powderPeso molecular:370.43Guanosine 5′-monophosphate disodium salt
CAS:Fórmula:C10H12N5Na2O8PPureza:98%Cor e Forma:Solid, Beige powderPeso molecular:407.1865-Bromo-6-chloro-3-indolyl phosphate disodium salt
CAS:Fórmula:C8H4BrClNNa2O4PPureza:95%Peso molecular:370.43ß-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt Hydrate, oxidized form [for Biochemical Research]
CAS:Fórmula:C21H27N7NaO17P3Pureza:90.0%Cor e Forma:SolidPeso molecular:765.391-(2-Hydroxyethyl)-1-methylguanidine dihydrogen phosphate
CAS:Fórmula:C4H12N3O4PPureza:98%Peso molecular:197.131
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