Sulfonamidas e Derivados
As sulfonamidas são compostos que contêm um grupo funcional sulfonamida (-SO₂NH₂), onde um átomo de enxofre está ligado a um grupo amino. Foram um dos primeiros antibióticos sintéticos usados na medicina, inibindo a síntese do ácido fólico nas bactérias, o que lhes confere propriedades antimicrobianas. São utilizadas principalmente para tratar infeções bacterianas, embora seu uso tenha diminuído devido à resistência antimicrobiana. Além do uso como antibióticos, as sulfonamidas também têm aplicações no tratamento de doenças como a malária e doenças inflamatórias intestinais.
Na CymitQuimica, oferecemos sulfonamidas e seus derivados com alto grau de pureza para pesquisa em microbiologia e desenvolvimento farmacêutico.
Foram encontrados 2592 produtos de "Sulfonamidas e Derivados"
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Cotrimoxazole
CAS:<p>Applications Cotrimoxazole is an antibiotic. Pseudomonas aeruginosa has a drug resistant rate of 66% in the years 2010-2013.<br>References Sun, D., et. al.: Zhonghua Yiyuanganranxue Zazhi, 24, 345 (2014)<br></p>Fórmula:C24H29N7O6SCor e Forma:NeatPeso molecular:543.63,4,4'-Trichlorocarbanilide(Triclocarban)
CAS:Produto ControladoFórmula:C13H9Cl3N2OCor e Forma:White Crystalline PowderPeso molecular:315.58Dimethyl n-methylsulfamide
CAS:Pureza:97.0%Cor e Forma:Liquid, ClearPeso molecular:138.19000244140625Decarboxy Etodolac
CAS:Produto Controlado<p>Impurity Etodolac EP Impurity J<br>Applications Decarboxy Etodolac (Etodolac EP Impurity J) is an impurity of Etodolac (racemic, E933100), which is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). Etodolac displays anti-inflammatory effects in both adjuvant arthritic and normal rats. Etodolac is anti-inflammatory.<br>References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001)<br></p>Fórmula:C16H21NOCor e Forma:White To YellowPeso molecular:243.342-Chlorobenzoic Acid
CAS:<p>Impurity Mesalazine EP Impurity L<br>Applications The toxicity of halogenated benzoic acids was found to be directly related to the compound's hydrophobicity. Toxicity and quantitative structure-activity relationships of benzoic acids to Pseudokirchneriella subcapitata.<br>References Moore, D., et al.: Environ. Toxicol. Chem., 16, 794 (1997), Zhao, Y., et al.: Sci. Total Environ., 216, 205 (1998), Fiorentino, A., et al.: J. Agric.Food Chem., 51, 1005 (2003),<br></p>Fórmula:C7H5ClO2Cor e Forma:NeatPeso molecular:156.572,7-Diamino-6-phenyl-4-pteridinol
CAS:Produto Controlado<p>Impurity Triamterene EP Impurity B/ Triamterene USP Related Compound B<br>Applications 2,7-Diamino-6-phenyl-4-pteridinol has potential as a pteridine diuretic. Impurity in the synthesis of Triamterene (T767325), a weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys.<br>References Osdene, et al.: J. Med. Chem., 10, 431 (1967), Kapoor, V.K., et al.: Anal. Profiles Drug Subs. Excip., 23, 571 (1994); Weinstock, J. et al.: J. Med. Chem., 11, 573 (1968);<br></p>Fórmula:C12H10N6OCor e Forma:NeatPeso molecular:254.25Mordant Yellow 10 (Technical Grade)
CAS:Produto Controlado<p>Impurity Sulfasalazine Impurity I<br>Stability Light Sensitive<br>Applications Mordant Yellow 10 is a monoazo dye used in wool textiles. Mordant Yellow 10 is used as organic reagent for spectrometric determination of iron(III) as well as in the study of other metal complexations.<br>References Ledneva, I.A. Izvest. Vyssh. Ucheb. Zav. Tekh. Teks. Prom., 5, 58 (1986); Vladescu, L. et al.: Rev. Roum. Chem., 54, 85 (2009); Gupta, P.N. et al.: Asian J. Chem., 4, 15 (1992);<br></p>Fórmula:C13H8N2O6S·2NaCor e Forma:NeatPeso molecular:366.264-Acetaminophen-d3 Sulfate
CAS:Produto Controlado<p>Applications 4-Acetaminophen-d3 Sulfate is deuterium labeled metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961) (2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Fórmula:C82H3H6NO5SCor e Forma:White To Off-WhitePeso molecular:234.243-Hydroxyacetaminophen
CAS:Produto Controlado<p>Applications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Fórmula:C8H9NO3Cor e Forma:NeatPeso molecular:167.16(3RS)-1,3-Bis[4,-2-(methylpropyl)phenyl]butan-1-one
CAS:Produto ControladoFórmula:C24H32OCor e Forma:Colourless To Light YellowPeso molecular:336.51Tolbutamide-d9
CAS:Produto ControladoFórmula:C122H9H9N2O3SCor e Forma:White To Off-WhitePeso molecular:279.40Sulfathiazole
CAS:Produto Controlado<p>Applications Antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs. Excip., 22, 389 (1993),<br></p>Fórmula:C9H9N3O2S2Cor e Forma:WhitePeso molecular:255.325-Amino-1,3,4-thiadiazole-2-sulfonamide Hydrochloride Salt
CAS:Produto Controlado<p>Impurity Acetazolamide EP Impurity D Hydrochloride<br>Applications Acetazolamide intermediate. (Acetazolamide EP Impurity D Hydrochloride)<br>References Carta, F., et al.: Bioorg. Med. Chem. Lett., 19, 6649 (2009), Joseph, P., et al.: J. Med. Chem., 53, 2277 (2010), Srinivasu, P., et al.: J. Pharm. Biomed. Anal., 52, 142 (2010),<br></p>Fórmula:C2H5ClN4O2S2Cor e Forma:NeatPeso molecular:216.67Trimethoprim-d3
CAS:Produto Controlado<p>Applications Deuterated Trimethoprim, an antibacterial.<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Fórmula:C14D5H15N4O3Cor e Forma:Off WhitePeso molecular:297.3643-Oxo-1,2-benzoisothiazoline-2-acetic Acid Methyl Ester 1,1-Dioxide
CAS:<p>Impurity Piroxicam EP Impurity D<br>Applications Piroxicam impurity D.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Fórmula:C10H9NO5SCor e Forma:NeatPeso molecular:255.25Ibuprofen Alcohol
CAS:Produto Controlado<p>Applications Ibuprofen Alcohol (Ibuprofen EP Impurity P) is an impurity of Ibuprofen (I140000). Ibuprofen impurity P as per EP.<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Zhao, J., et al.: Anal. Chem., 72, 302 (2000), Kucera, R., et al.: J. Pharm. Biomed. Anal., 38, 609 (2005),<br></p>Fórmula:C13H20OCor e Forma:Colourless To Light YellowPeso molecular:192.306,6'-Oxybis-2-naphthalenesulfonic Acid Disodium Salt (>85%)
CAS:Produto Controlado<p>Applications An impurity contained in the commercial food Yellow No.5 (Sunset Yellow FCF) which has a potent mutagenicity effect.<br>References Yamada, M., et al.: Chem. Pharm. Bull., 44, 1624 (1996), Yamada, M., et al.: J. Food Chem., 3, 151 (1996),<br></p>Fórmula:C20H12O7S2·2NaPureza:>90%Cor e Forma:White To Light GreyPeso molecular:474.41Glimepiride
CAS:<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ratheiser, K., et al.: Arzneim.-Forsch., 43, 856, (1993),<br></p>Fórmula:C24H34N4O5SCor e Forma:NeatPeso molecular:490.624-Nitro Sulfamethoxazole
CAS:Produto Controlado<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Fórmula:C10H9N3O5SCor e Forma:Light BrownPeso molecular:283.263-Desmethyl Trimethoprim
CAS:Produto Controlado<p>Applications 3-Desmethyl Trimethoprim is a metabolite of Trimethoprim (T795615); an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. 3-Desmethyl Trimethoprim gets excreted in the urine of rats, dogs, and man in the form of glucuronides.<br>References Roth, B., et al.: J. Med. Chem., 24, 933 (1981); Liu, Z., et al.: Biomed. Chromatogr., 26, 1101 (2012); Schwartz, D. E., Arzneimittel-Forsch., 20, 1867 (1970)<br></p>Fórmula:C13H16N4O3Cor e Forma:White To Light BrownPeso molecular:276.29Diacetic Aceclofenac
CAS:Produto Controlado<p>Impurity Aceclofenac EP Impurity H<br>Applications A 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative as anti-inflammmatory and analgesic agent. (Aceclofenac EP Impurity H)<br></p>Fórmula:C20H17Cl2NO8Cor e Forma:White To Off-WhitePeso molecular:470.26Terizidone
CAS:Produto Controlado<p>Applications A drug used to treat tuberculosis.<br>References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005),<br></p>Fórmula:C14H14N4O4Cor e Forma:NeatPeso molecular:302.294-Hydroxy Trimethoprim
CAS:<p>Applications Trimethoprim (T795615) derivative. Antibacterial properties.<br></p>Fórmula:C14H18N4O4Cor e Forma:NeatPeso molecular:306.32Pyroxasulfone
CAS:Produto Controlado<p>Applications Pyroxasulfone is an inhibitor of the biosynthesis of very-long-chain fatty acids. Pyroxasulfone is also used to control grass weed species in pre-emergence in major field crops.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Busi, R., et al.: Pest. Manag. Sci., 72, 1665 (2016)<br></p>Fórmula:C12H14F5N3O4SCor e Forma:WhitePeso molecular:391.31Napropamid
CAS:<p>Applications Napropamid is used as a pesticide.<br>References She-feng, J., et al.: Nanjing Nongye Daxue Xuebao, 35, 137 (2012);<br></p>Fórmula:C17H21NO2Cor e Forma:Light Orange Color To Light BrownPeso molecular:271.35Phenacetin
CAS:Produto Controlado<p>Applications Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959), Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983),<br></p>Fórmula:C10H13NO2Cor e Forma:WhitePeso molecular:179.22Despyridyl Piroxicam (Piroxicam Impurity C)
CAS:Produto ControladoFórmula:C10H10N2O4SCor e Forma:NeatPeso molecular:254.261,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester
CAS:<p>Impurity Etodolac EP Impurity K<br>Applications 1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester (Etodolac EP Impurity K) is a derivative of Etodolac.<br>References Caldwell, J., et al.: Biochem. Pharmacol., 37, 105 (1988), Drummer, O., et al.: J. Anal. Toxicol., 17, 225 (1993)<br></p>Fórmula:C18H23NO3Cor e Forma:White To Off-WhitePeso molecular:301.38Diclosan
CAS:<p>Applications Diclosan is used in the treatment of halogenated phenolic compounds by sequential tri-metal reduction and laccase-catalytic oxidation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dai, Y., et al.: Water Res., 71, 64 (2015);<br></p>Fórmula:C12H8Cl2O2Cor e Forma:White PowderPeso molecular:255.10Acetanilide (Acetylaniline)
CAS:Produto Controlado<p>Impurity Paracetamol EP Impurity D<br>Applications Acetanilide (Acetylaniline) the first aniline derivative found to possess analgesic and antipyretic properties (1,2). It is also an impurity of Acetaminophen (A161220).<br>References (1) Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010) (2) Chang, C., et al.: J. Nat. Prod., 73, 229 (2010)<br></p>Fórmula:C8H9NOCor e Forma:White To Light BrownPeso molecular:135.16Furosemide
CAS:Produto Controlado<p>Applications Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic. Non-competitve subtype-specific blocker of GABAA. Neuroprotective & Neuroresearch Products.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979); Korpi, E. et al.: Mol. Pharmacology, 47, 283 (1995);<br></p>Fórmula:C12H11ClN2O5SCor e Forma:White To Off-WhitePeso molecular:330.74Niflumic Acid
CAS:Produto Controlado<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Fórmula:C13H9F3N2O2Cor e Forma:Light YellowPeso molecular:282.22Ibuprofen Carboxylic Acid(Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications The major metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes.<br>References Bhuyan, K., et al.: Life Sci., 38, 1463 (1986), Blakytny, R., et al.: Biochem. J., 288, 303 (1992),Ganea, E., et al.: Eur. J. Biochem., 231, 181 (1995), Mitchell, J., et al.: Br. J. Pharmacol., 128, 1121 (1999),<br></p>Fórmula:C13H16O4Cor e Forma:White SolidPeso molecular:236.264-Acetamidobenzenesulfonic Acid
CAS:Produto Controlado<p>Impurity Sulfadimethoxine EP Impurity C<br>Stability Hygroscopic<br>Applications 4-Acetamidobenzenesulfonic Acid (Sulfadimethoxine EP Impurity C) is a metabolite of Sulfanilic acid.<br>References Saab, N., et al.: Eur. J. Med. Chem., 34, 745 (1999), Kim, H., et al.: J. Pharm. Biomed. Anal., 27, 51 (2002), Santelli-Rouvier, C., et al.: Eur. J. Med. Chem., 39, 735 (2004),<br></p>Fórmula:C8H9NO4SCor e Forma:NeatPeso molecular:215.23Benzylhydrochlorothiazide
CAS:Produto ControladoFórmula:C14H14ClN3O4S2Cor e Forma:NeatPeso molecular:387.86Hydroflumethiazide-13CD2
CAS:Produto Controlado<p>Applications Labelled Hydroflumethiazide. Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Fórmula:C713CH6D2F3N3O4S2Cor e Forma:NeatPeso molecular:334.30rac 1-Nitroso-2-methylindoline
CAS:Produto ControladoFórmula:C9H10N2OCor e Forma:BrownPeso molecular:162.19N-Nitroso Furosemide ( >80%)
CAS:Fórmula:C12H10ClN3O6SPureza:>80%Cor e Forma:Light Orange To Dark OrangeMethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide
CAS:Produto Controlado<p>Impurity Piroxicam EP Impurity G<br>Applications Piroxicam impurity G.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Pharmacol., 36, 79 (1996), Bihovsky, R., et al.: Bioorg. Med. Chem. Lett., 14, 1035 (2004),<br></p>Fórmula:C10H9NO5SCor e Forma:NeatPeso molecular:255.254-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-2(1H)-pyrimidinone
CAS:Produto Controlado<p>Impurity USP Trimethoprim Related Compound A<br>Applications 6-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-2(1H)-pyrimidinone, is an impurity of Trimethoprim (T795615), an antibacterial agent.<br>References Popov, V. M., et al.: Bioorg. Med. Chem. Lett., 16, 4366 (2006); Brogden, R.N., et al.: Drugs, 23, 405 (1982);<br></p>Fórmula:C14H17N3O4Cor e Forma:WhitePeso molecular:291.30Glimepiride-d5
CAS:Produto Controlado<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ratheiser, K., et al.: Arzneimittel-Forsch., 43, 856, (1993),<br></p>Fórmula:C24H29D5N4O5SCor e Forma:Off-WhitePeso molecular:495.65Dehydro Indapamide
CAS:Produto Controlado<p>Impurity Indapamide USP Related Compound A/ Indapamide EP Impurity B<br>Applications A metabolite of Indapamide (M5). A dehydrogenation pathway by cytochromes P450. Indapamide USP Related Compound A<br>References Tamura A., et al.: Chem. Pharm. Bull., 38, 225 (1990), Harlow, G.R., et al.: J. Biol. Chem., 272, 5396 (1997), Ozden, T., et al.: Pharm. Pharmacol. Commun., 4, 397 (1998), Gruciani, G., et al.: J. Med. Chem., 48, 6970 (2005), Sun, H., et al.: Drug. Metab. Dispos., 37, 672 (2009),<br></p>Fórmula:C16H14ClN3O3SCor e Forma:White To Light BrownPeso molecular:363.823-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid
CAS:<p>Impurity Bumetanide Impurity A<br>Applications 3-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid is a compound related to Piretanide (P508700) and an intermediate in the production of Bumetanide, Bumetanide Impurity A (B689550).<br></p>Fórmula:C13H10N2O7SCor e Forma:NeatPeso molecular:338.29Ibuprofen Dimer
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity G<br>Applications Ibuprofen Dimer (Ibuprofen EP Impurity G) is a dimer impurity of Ibuprofen (I140000).<br></p>Fórmula:C26H32O4Cor e Forma:Light Orange ColourPeso molecular:408.53rac Ibuprofen-d3
CAS:Produto Controlado<p>Applications Labelled Ibuprofen, a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Fórmula:C132H3H15O2Cor e Forma:Off-WhitePeso molecular:209.30Bis(4-hydroxyphenyl) Sulfone
CAS:Produto Controlado<p>Applications Bis(4-hydroxyphenyl) Sulfone is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.<br>References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012);<br></p>Fórmula:C12H10O4SCor e Forma:WhitePeso molecular:250.274-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide
CAS:<p>Impurity Glimepiride EP Impurity B/ USP Glimepiride Related Compound B<br>Applications 4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide (Glimepiride EP Impurity B) is an intermediate for the preparation of Glimepiride.<br></p>Fórmula:C16H21N3O4SCor e Forma:Off-WhitePeso molecular:351.42N,N-Dimethylnicotinamide-2-sulfonamide
CAS:Produto Controlado<p>Applications N,N-Dimethylnicotinamide-2-sulfonamide (cas# 112006-75-4) is a compound useful in organic synthesis.<br></p>Fórmula:C8H11N3O3SCor e Forma:NeatPeso molecular:229.262-Amino-5-chlorobenzenesulfonamide
CAS:Produto Controlado<p>Applications 2-Amino-5-chlorobenzenesulfonamide is a metabolite of IDRA-21 (I232500), which inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).<br>References Cannazza, G., et. al.: Bioorg. Med. Chem. Lett., 19, 1254 (2009); Zivkovic, et al.: J. Pharmacol. Exp. Ther., 272, 300 (1995); Dingledine, R., et al.: Pharmacol. Rev., 51, 7 (1999); Sun, Y., et al.: Nature, 417, 245 (2002); Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006)<br></p>Fórmula:C6H7ClN2O2SCor e Forma:NeatPeso molecular:206.65Indomethacin Diamide
CAS:Produto Controlado<p>Applications Indomethacin Diamide is an impurity of Indomethacin (I641000), an non-steroidal anti-inflammatory drug commonly used in the treatment of fever, pain and swelling.<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Fórmula:C33H27Cl2N3O5Cor e Forma:NeatPeso molecular:616.49Hydrochlorothiazide-13C,15N2,d2
CAS:Produto Controlado<p>Applications Labelled Hydrochlorothiazide (H714560). Hydrochlorothiazide is a carbonic anhydrase inhibitor as a diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Deppeler, H.P., et al.: Anal. Profiles Drug Subs., 10, 405 (1981),<br></p>Fórmula:C613CH6D2ClN15N2O4S2Cor e Forma:NeatPeso molecular:302.73Nafamostat Mesylate
CAS:<p>Applications A non-peptide proteaseinhibitor.<br>References Ayoyama, T., et al.: Chem. Pharm. Bull., 33, 1458 (1985)<br></p>Fórmula:C19H17N5O2·2CH4O3SCor e Forma:NeatPeso molecular:539.58Sulfadiazine-13C6
CAS:<p>Applications The isotopically labelled drug Sulfadiazine. Antibacterial.<br>References Bohni, et al.: Chemotherapy, 14, 195 (1969), Carr, et al.: Antimicrob. Agents Chemother., 4, 585 (1973), Stober, H., et al.: Anal. Profiles Drug Subs., 11, 523 (1982),<br></p>Fórmula:C6C4H10N4O2SCor e Forma:Off-WhitePeso molecular:256.23rac Bendroflumethiazide-d5
CAS:Produto ControladoFórmula:C15H9D5F3N3O4S2Cor e Forma:NeatPeso molecular:426.453-Ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-1H-pyrrole-1-carboxamide
CAS:Produto Controlado<p>Applications Intermediate for the preparation of Glimepiride.<br></p>Fórmula:C16H20N2O2Cor e Forma:NeatPeso molecular:272.344-Acetamidophenyl β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Acetamidophenyl β-D-Glucuronide is a major urinary metabolite of Acetaminophen (A161220) (Paracetamol) in human (1). Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis (2,3).<br>References (1) Johnston, D., et al.: J. Chem. Res., Synop., 12, 406 (1988)(2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Fórmula:C14H16NO8·NaCor e Forma:White To Light RedPeso molecular:349.272-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(1H)-pyrimidinone
CAS:Produto Controlado<p>Applications Degradation product/impurity of trimethoprim (T795615).<br>References Roth, B., et al.: J., Med. Pharm. Chem., 5, 1103 (1962), Bergh, J., et al.: J. Pharm. Sci., 78, 348 (1989),<br></p>Fórmula:C14H17N3O4Cor e Forma:NeatPeso molecular:291.30rac 2-(4-Formylphenyl)propionic Acid (Ibuprofen Impurity K)
CAS:<p>Impurity Ibuprofen EP Impurity K<br>Applications rac 2-(4-Formylphenyl)propionic Acid (Ibuprofen EP Impurity K) is a degradation product of Ibuprofen arising from oxidative and thermal treatments. Ibuprofen impurity K.<br>References Heikkinen, L., et al.: Acta Pharm. Fenn., 92, 275 (1983), Vargas, F., et al.: Pharmazie, 11, 767 (1991), Lee, J., et al.: Pharm. Res., 9, S170 (1995),<br></p>Fórmula:C10H10O3Cor e Forma:White To Light YellowPeso molecular:178.181-Propyl Etodolac
CAS:Produto Controlado<p>Impurity Etodolac EP Impurity G<br>Applications 1-Propyl Etodolac (Etodolac EP Impurity G) is an impurity in the synthesis of Etodolac (E933100), may have use in the treatment of myeloma. COX-1/COX-2/β-catenin inhibitors, or anti-inflammatory agent.<br>References Robinson, W. et al.: J. Pharm. Exp. Ther., 203, 729 (1977); Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001);<br></p>Fórmula:C18H23NO3Cor e Forma:NeatPeso molecular:301.38(R)-(-)-Etodolac
CAS:Produto Controlado<p>Applications The R-enantiomer of Etodolac (E933090). Anti-inflammatory; analgesic.<br>References Boxenbaum, H., et al.: J. Pharmacokin. Biopharm., 10, 201 (1982), Iwatsubo, T., et al.: Biopharm. Drug Dispos., 17, 273 (1996), Obach, R., et al.: J. Pharmacol. Exp. Ther., 283, 46 (1997),<br></p>Fórmula:C17H21NO3Cor e Forma:NeatPeso molecular:287.3544-Chloro-3-sulfamoylbenzoic Acid
CAS:Produto ControladoFórmula:C7H6ClNO4SCor e Forma:NeatPeso molecular:235.64Phenacetin-d3
CAS:Produto Controlado<p>Applications Phenacetin-d3 is the labeled analogue of Phenacetin (P294580), an analgesic, antipyretic; component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959); Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983)<br></p>Fórmula:C10H10D3NO2Cor e Forma:NeatPeso molecular:182.234-Demethyltrimethoprim
CAS:<p>Applications 4-Demethyltrimethoprim is an impurity of Trimethoprim (T795615), an antibacterial agent.<br>References Mengelers, M.J.B., et al.: J. Vetern. Pharmacol. Therap., 20, 24 (1997); Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Fórmula:C13H16N4O3Cor e Forma:NeatPeso molecular:276.29Saccharin Sodium Salt Dihydrate
CAS:Fórmula:C7H4NO3S·Na·2H2OCor e Forma:White Crystalline PowderPeso molecular:241.20Mesosulfuron-methyl
CAS:<p>Stability Unstable in Solution<br>Applications Mesosulfuron-methyl can be used in biological study of targeted screening and safety evaluation of 276 agrochemical residues in raisins using buffered ethyl acetate extraction and liquid chromatography-tandem mass spectrometry analysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shabeer, T. P. A., et al.: Chemosphere, 184, 1036 (2017)<br></p>Fórmula:C17H21N5O9S2Cor e Forma:NeatPeso molecular:503.512-Amino-4-chloro-5-sulfamoyl-o-benzotoluidide
CAS:Produto Controlado<p>Applications 2-Amino-4-chloro-5-sulfamoyl-o-benzotoluidide is an intermediate in the synthesis of Metolazone (M338750); a diuretic and antihypertensive agent.<br>References Curry, C.L., et al.: Clin. Ther., 9, 47 (1986); Kiyingi, A., et al.: Lancet, 335, 29 (1990); Chen, G., et al.: Shenyang Yaoke Daxue Xuebao, 21, 109 (2004)<br></p>Fórmula:C14H14ClN3O3SCor e Forma:NeatPeso molecular:339.82-Acetamido-5-mercapto-1,3,4-thiadiazole
CAS:Produto Controlado<p>Impurity Acetazolamide EP Impurity C<br>Applications Acetazolamide intermediate. Acetazolamide EP Impurity C<br>References Almajan, G., et al.: Bioorg. Med. Chem. Lett., 15, 2347 (2005), Talath, S., et al.: Eur. J. Med. Chem., 41, 918 (2006), Srinivasu, P., et al.: J. Pharm. Biomed. Anal., 52, 142 (2010),<br></p>Fórmula:C4H5N3OS2Cor e Forma:NeatPeso molecular:175.23Dapsone Hydroxylamine-d4
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications A labelled metabolite of Dapsone.<br>References Preuss, C.V., et al.: Biochem. Pharmacol., 51, 1661 (1996),<br></p>Fórmula:C12H8D4N2O3SCor e Forma:NeatPeso molecular:268.324,4’-Dichlorodiphenyl Sulfone
CAS:Produto Controlado<p>Applications 4,4’-Dichlorodiphenyl Sulfone is an impurity of Dapson (D193250), an antibacterial used in the treatment of dermatitis herpetiformis.<br>References Carlsson, L., et al.: J. Chem. Info. Model., 49, 2551 (2009); Chan, T.S., et al.: Toxicol. App. Pharmacol., 232, 456 (2008);<br></p>Fórmula:C12H8Cl2O2SCor e Forma:Off-WhitePeso molecular:287.161,2-Benzisoxazole-3-methanesulfonate Sodium Salt
CAS:Produto ControladoFórmula:C8H6NO4S·NaCor e Forma:NeatPeso molecular:235.19Mesotrione
CAS:<p>Applications Mesotrione is a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of lepospermone.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deng, L., et al.: Indus. Crops. Prod., 39, 154 (2012); Pileggi, M., et al.: Chemosphere., 86, 1127 (2012); McElroy, J., S., Hort. Technol.,22, 627 (2012);<br></p>Fórmula:C14H13NO7SCor e Forma:Light YellowPeso molecular:339.32N2-Methyl Trimethoprim (Impurity)
CAS:Produto Controlado<p>Applications N2-Methyl Trimethoprim is an impurity of Trimethoprim (T795615), an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections.<br>References Dauber-Osguthorpe, P., et al.: Proteins, 4, 31, (1988); Darrell, J., et al.: J. Clin. Pathol., 21, 202 (1968); Zhanel, G., et al.: Antimicrob. Agents Ch., 44, 1089 (2000)<br></p>Fórmula:C15H20N4O3Cor e Forma:NeatPeso molecular:304.34Zonisamide-d4
CAS:Produto Controlado<p>Applications Labelled sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant.<br>References Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980), Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987), Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993), Sorkin, E.M., et al.: Drugs, 45, 760 (1993),<br></p>Fórmula:C82H4H4N2O3SCor e Forma:Light Brown SolidPeso molecular:216.25Nimesulide
CAS:<p>Applications Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)<br></p>Fórmula:C13H12N2O5SCor e Forma:Light YellowPeso molecular:308.31rac Bendroflumethiazide
CAS:Produto ControladoFórmula:C15H14F3N3O4S2Cor e Forma:WhitePeso molecular:421.41Dapsone-d4
CAS:Produto Controlado<p>Applications A labelled antibacterial used in the treatment of dermatitis herpetiformis.<br>References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Fórmula:C12H8D4N2O2SCor e Forma:NeatPeso molecular:252.332-Methylindole
CAS:Produto Controlado<p>Applications 2-Methylindole is an intermediate in the synthesis of indole derivative with potential antifungal activities.<br>References Rodriguez, S., et al.: Natural. Prod. Res., 22, 253 (2008); Zhang, B.G., et al.: Bioresource., 100, 5687 (2009);<br></p>Fórmula:C9H9NCor e Forma:NeatPeso molecular:131.1745Hydrochlorothiazide
CAS:Fórmula:C7H8ClN3O4S2Cor e Forma:White Crystalline PowderPeso molecular:297.74N-(Methylsulfonyl)-4-(desnitro) Nimesulide
CAS:<p>Impurity Nimesulide EP Impurity E<br>Applications N-(Methylsulfonyl)-4-(desnitro) Nimesulide is an impurity of Nimesulide (N477500).<br>References Kulkarni, S., et al.: Curr. Sci., 83, 1442 (2002), Nguyen, D., et al.: J. Sep. Sci., 29, 1836 (2006), Zacharis, C., et al.: J. Pharm. Biomed. Anal., 49, 726 (2009),<br></p>Fórmula:C14H15NO5S2Cor e Forma:NeatPeso molecular:341.40N-(p-Chlorobenzoyl)-p-anisidine
CAS:Produto Controlado<p>Applications N-(p-Chlorobenzoyl)-p-anisidine is a COX-1 inhibitor analgesics that do not cause gastric damage.<br>References Kakuta, H., et al.: J. Med. Chem., 51, 2400 (2008);<br></p>Fórmula:C14H12ClNO2Cor e Forma:White To Off-WhitePeso molecular:261.7Ibuprofen Lysinate
CAS:Produto Controlado<p>Applications Ibuprofen Lysinate is used in the treatment of hemodynamically significant patent ductus arteriosus in neonates greater than 27 week gestational age.<br>References Pai, V.B., et. al.: Pharmacotherapy, 28, 1162 (2008)<br></p>Fórmula:C13H18O2·C6H14N2O2Cor e Forma:YellowPeso molecular:352.468N-(2-Pyridyl)oxamic Acid
CAS:Produto Controlado<p>Applications A metabolite of Tenoxicam (T019500). A degradation product and pathway of Lornoxicam.<br>References Tsuchiya, S., et al.: Cancer Res., 42, 1530 (1982), Talanian, R., et al.: J. Med. Chem., 43, 3351 (2000), Fuentes-Prior, P., et al.: Biochem. J., 384, 201 (2004), Han, Y., et al.: Bioorg. Med. Chem. Lett., 15, 1173 (2005),<br></p>Fórmula:C7H6N2O3Cor e Forma:WhitePeso molecular:166.132’-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 2’-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine Hydrochloride is an impurity of Sulfasalzine (S699084).<br></p>Fórmula:C29H22N6O7S2•xHClPureza:>85%Cor e Forma:NeatPeso molecular:630.65 + x(36.46)rac 2-Hydroxy Ibuprofen
CAS:Produto Controlado<p>Applications A human metabolite of Ibuprofen.<br>References Bales, J., et al.: Clin. Chem., 31, 757 (1985), Maurer, H., et al.: J. Anal. Toxicol., 25, 237 (2001), Zwiener, C., et al.: Anal. Bioanal. Chem., 372, 569 ( 2002), de Bernardi, B., et al.: J. Clin. Oncol., 21, 1592 (2003),<br></p>Fórmula:C13H18O3Cor e Forma:Off-WhitePeso molecular:222.284,4'-Bis(4-aminobenzenesulfonyl)hydrazobenzene
<p>Stability Light Sensitive<br>Applications 4,4'-Bis(4-aminobenzenesulfonyl)hydrazobenzene is a dimer impurity of Dapsone (D193250); an antibacterial used in the treatment of dermatitis herpetiformis.<br>References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950); Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009); Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009); Varma, M., et al.: J. Med. Chem., 52, 4844 (2009)<br></p>Fórmula:C24H22N4O4S2Cor e Forma:Off WhitePeso molecular:494.59Brinzolamide Hydrochloride
CAS:Produto Controlado<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Fórmula:C12H21N3O5S3·ClHCor e Forma:NeatPeso molecular:419.97Isosulfamethoxazole
CAS:<p>Applications Isosulfamethoxazole is an impurity of the antibacterial drug Sulfamethoxazole (S699086). It is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 467 (1973), Wormser, G.P., et al.: Drugs, 24, 459 (1982), Wharton, M., et al.: Ann. Intern. Med., 105, 37 (1986),<br></p>Fórmula:C10H11N3O3SCor e Forma:NeatPeso molecular:253.28Methazolamide
CAS:Produto Controlado<p>Applications Methazolamide is a carbonic anhydrase inhibitor. Methazolamide is used in the treatment of glaucoma.<br>References Iyer, G.R. et al.: J. Pharmac. Biomed. Anal., 16, 1021 (1998); Maren, T. H. et al.: Invest. Ophthamol. Vis. Sci., 16, 730 (1977);<br></p>Fórmula:C5H8N4O3S2Cor e Forma:NeatPeso molecular:236.277-Ethyltryptophol
CAS:<p>Impurity Etodolac EP Impurity H<br>Applications 7-Ethyltryptophol (Etodolac EP Impurity H) is a key intermediate in the preparation of the non-steroidal anti-inflammatory drug Etodolac.<br>References El Kousy, N., et al.: J. Pharm. Biomed. Anal., 20, 185 (1999),<br></p>Fórmula:C12H15NOCor e Forma:WhitePeso molecular:189.25Tolnaftate
CAS:Produto Controlado<p>Applications Antifungal.<br>References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Fórmula:C19H17NOSCor e Forma:NeatPeso molecular:307.41Sulfachloropyridazine
CAS:<p>Applications Sulfachloropyridazine is an antibacterial compound.This compound is a contaminant of emerging concern (CECs).<br>References Wammer, K.: Environ. Toxicol. Chem. 25, 1480 (2006);<br></p>Fórmula:C10H9ClN4O2SCor e Forma:WhitePeso molecular:284.72Cantrodifene
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications 4-Isothiocyanato-4'-nitrodiphenyl ether (cas# 19881-18-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C13H8N2O3SCor e Forma:NeatPeso molecular:272.27N-Acetyl Sulfadiazine-d4 (Major)
CAS:Produto Controlado<p>Applications A major labelled metabolite of Sulfadiazine.<br>References Woolley, J., et al.: Drug Metab. Dispos., 7, 94 (1979), Nielsen, P., et al.: Biochem. Pharmacol., 35, 2509 (1986), Anari, M., et al.: Anal. Chem., 76, 823 (2004), Edlund, P., et al.: J. Pharm. Biomed. Anal., 34, 1079 (2004),<br></p>Fórmula:C12H8D4N4O3SCor e Forma:NeatPeso molecular:296.34
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