Sulfonamidas e Derivados
As sulfonamidas são compostos que contêm um grupo funcional sulfonamida (-SO₂NH₂), onde um átomo de enxofre está ligado a um grupo amino. Foram um dos primeiros antibióticos sintéticos usados na medicina, inibindo a síntese do ácido fólico nas bactérias, o que lhes confere propriedades antimicrobianas. São utilizadas principalmente para tratar infeções bacterianas, embora seu uso tenha diminuído devido à resistência antimicrobiana. Além do uso como antibióticos, as sulfonamidas também têm aplicações no tratamento de doenças como a malária e doenças inflamatórias intestinais.
Na CymitQuimica, oferecemos sulfonamidas e seus derivados com alto grau de pureza para pesquisa em microbiologia e desenvolvimento farmacêutico.
Foram encontrados 2592 produtos de "Sulfonamidas e Derivados"
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Trimethoprim Lactate Salt
CAS:Produto Controlado<p>Applications Trimethoprim lactate salt is an antibacterial agent.<br>References Lees, G. et al.: Brit. J. Pharmacol., 73, 535 (1981);<br></p>Fórmula:C14H18N4O3·C3H6O3Cor e Forma:NeatPeso molecular:290.32 + (90.08)Glyburide-d3 (methoxy-d3)
CAS:Produto Controlado<p>Applications Glyburide-d3 (methoxy-d3) (CAS# 1219803-02-7) is a useful isotopically labeled research compound.<br></p>Fórmula:C23D3H25ClN3O5SCor e Forma:NeatPeso molecular:497.0224-Acetaminophen Sulfate Potassium Salt
CAS:Produto ControladoFórmula:C8H8NO5S·KCor e Forma:BeigePeso molecular:269.32Iso Furosemide
CAS:<p>Impurity Furosemide EP Impurity A<br>Applications Iso Furosemide (Furosemide EP Impurity A) is a Furosemide (F865000) derivative which enhanced urinary excretion of active kallikrein.<br>References Kirk, K., et al.: J. Biol. Chem., 267, 23475 (1992), Kirk, K., et al.: Biochem. J., 311, 761 (1995), Egee, S., et al.: J. Physiol., 542, 795 ( 2002),<br></p>Fórmula:C12H11ClN2O5SCor e Forma:Light BrownPeso molecular:330.74Dapsone
CAS:Produto Controlado<p>Applications An antibacterial used in the treatment of dermatitis herpetiformis.<br>References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Fórmula:C12H12N2O2SCor e Forma:NeatPeso molecular:248.30Sulfamethoxazole N4-glucoside (α/β mixture)
CAS:<p>Applications Sulfamethoxazole N4-glucoside is a metabolite of Sulfamethoxazole (S699086) which is an anti bacterial drug. Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 467 (1973), Wormser, G.P., et al.: Drugs, 24, 459 (1982), Wharton, M., et al.: Ann. Intern. Med., 105, 37 (1986),<br></p>Fórmula:C16H21N3O8SCor e Forma:White To Light Orange ColourPeso molecular:415.42Sulfasalazine 3-Isomer
CAS:Produto Controlado<p>Impurity Sulfasalazine EP Impurity F<br>Stability Hygroscopic<br>Applications A positional isomeric impurity of Sulfasalazine (S699084). Sulfasalazine EP Impurity F<br>References Zalipsky, J.J. et al.: J. Pharmac. Sci., 67, 387 (1978);<br></p>Fórmula:C18H14N4O5SCor e Forma:NeatPeso molecular:398.39Aceclofenac Methyl Ester
CAS:Produto Controlado<p>Impurity Aceclofenac EP Impurity D<br>Applications Aceclofenac Methyl Ester (Aceclofenac EP Impurity D) is a 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative as anti-inflammmatory and analgesic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C17H15Cl2NO4Cor e Forma:Off-WhitePeso molecular:368.21Sulfamethizole
CAS:<p>Applications Sulfamethizole is a sulfonamide based antibiotic that exhibit bactericidal activities towards gram-negative bacteria. Sulfamehizole was shown to be effective in treating gram-negative Bacillus AmpC enzyme in elderly patients with lower respiratory tract infection and as well as against microbs responsible for tuberculosis.<br>References Mondelli, M., et al.: J. Molec. Struct., 1036, 180 (2013); Leelakrishnana, S., et al.: Adv. App. Sci. Res., 3, 3502 (2012); Ghoreishi, S.M., et al.: Anal. Lett., 46, 323 (2012);<br></p>Fórmula:C9H10N4O2S2Cor e Forma:WhitePeso molecular:270.33132-(p-sec-Butylphenyl)propionic Acid
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity O<br>Applications 2-(p-sec-Butylphenyl)propionic Acid (Ibuprofen EP Impurity O) is an impurity of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Fórmula:C13H18O2Cor e Forma:NeatPeso molecular:206.28Trimethoprim-d9 (Major)
CAS:Produto Controlado<p>Applications Deuterated Trimethoprim, an antibacterial.contains 90% D9, 10% D6 and no D0<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Fórmula:C14D9H9N4O3Cor e Forma:Off-WhitePeso molecular:299.37Glibornuride
CAS:Produto Controlado<p>Applications Glibornuride has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. Glibornuride is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mielsen-Kudsk, J.E., Thirstrup, S.: Pulm. Pharmacol., 6, 185 (1993); Bodmer, M., et. al.: Diabetes Care, 31, 2086 (2008)<br></p>Fórmula:C18H26N2O4SCor e Forma:White To Off-WhitePeso molecular:366.485-Chloro Hydrochlorothiazide
CAS:Produto Controlado<p>Impurity Hydrochlorothiazide 5-Chloro Impurity<br>Applications Hydrochlorothiazide derivative. Diuretic agent.<br>References Mayer, S.E., et al.: J. Pharmacol. Exp. Therap., 134, 18 (1961),<br></p>Fórmula:C7H7Cl2N3O4S2Cor e Forma:Off White SolidPeso molecular:332.182,3-Dimethyl-N-phenylbenzenamine
CAS:Produto Controlado<p>Applications 2,3-Dimethyl-N-phenylbenzenamine is a lipophilic compound that is a commonly used non-steroidal anti-inflammatory drug (NSAID).<br>References El Haj, B. M., et al.: Forensic Sci. Int., 105, 141 (1999); Velkov, T., et al.: Chem. Biol., 14, 453 (2007)<br></p>Fórmula:C14H15NCor e Forma:White To BeigePeso molecular:197.28Saccharin N-(2-Acetic Acid Ethyl Ester)(Piroxicam Impurity E)
CAS:Produto Controlado<p>Impurity Piroxicam EP Impurity E<br>Applications Piroxicam impurity E.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Fórmula:C11H11NO5SCor e Forma:White To Off-WhitePeso molecular:269.27(S)-(+)-Ibuprofen-d3
CAS:Produto Controlado<p>Applications A labelled nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Fórmula:C13H15D3O2Cor e Forma:NeatPeso molecular:209.3Nicosulfuron
CAS:Produto Controlado<p>Stability Hygroscopic, Unstable in DMSO<br>Applications Post-emergence sulfonylurea herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gubbiga, N.G., et al.: Weed Technol., 9, 574 (1995), Ukrainczyk, L., et al.: J. Agric. Food Chem., 43, 855 (1995)<br></p>Fórmula:C15H18N6O6SCor e Forma:White To Off-WhitePeso molecular:410.40
