Sulfonamidas e Derivados
As sulfonamidas são compostos que contêm um grupo funcional sulfonamida (-SO₂NH₂), onde um átomo de enxofre está ligado a um grupo amino. Foram um dos primeiros antibióticos sintéticos usados na medicina, inibindo a síntese do ácido fólico nas bactérias, o que lhes confere propriedades antimicrobianas. São utilizadas principalmente para tratar infeções bacterianas, embora seu uso tenha diminuído devido à resistência antimicrobiana. Além do uso como antibióticos, as sulfonamidas também têm aplicações no tratamento de doenças como a malária e doenças inflamatórias intestinais.
Na CymitQuimica, oferecemos sulfonamidas e seus derivados com alto grau de pureza para pesquisa em microbiologia e desenvolvimento farmacêutico.
Foram encontrados 2592 produtos de "Sulfonamidas e Derivados"
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5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonic Acid Potassium Salt
CAS:Produto Controlado<p>Impurity Acetazolamide EP Impurity E<br>Applications 5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonic Acid is an impurity of Acetazolamide (A161500). (Acetazolamide EP impurity E)<br>References Zarghi, A., et al.: J. Pharm. Biomed. Anal., 28, 169 (2002), Subbarao, D., et al.: J. Chromatogr., 67, 841 (2008),<br></p>Fórmula:C4H4KN3O4S2Cor e Forma:NeatPeso molecular:261.32p-Ethylhydratropic Acid
CAS:<p>Impurity Ibuprofen EP Impurity N<br>Applications p-Ethylhydratropic Acid (Ibuprofen EP Impurity N) is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).<br></p>Fórmula:C11H14O2Cor e Forma:WhitePeso molecular:178.233-(4-Isobutylphenyl)propanoic Acid
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity F<br>Applications 3-(4-Isobutylphenyl)propanoic acid (Ibuprofen EP Impurity F) is an impurity of Ibuprofen (I140000). Ibuprofen impurity F as per EP.<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Zhao, J., et al.: Anal. Chem., 72, 302 (2000), Kucera, R., et al.: J. Pharm. Biomed. Anal., 38, 609 (2005),<br></p>Fórmula:C13H18O2Cor e Forma:NeatPeso molecular:206.285-Oxomefruside
CAS:<p>Applications 5-Oxomefruside is a lactone metabolite and impurity of the drug Mefruside (M205150).<br>References Puetter, J., et al.: Biochimica et Biophysica Acta, General Subjects, 286, 186 (1972).<br></p>Fórmula:C13H17ClN2O6S2Cor e Forma:NeatPeso molecular:396.87Bumetanide 3-(Butyl(nitroso)amino)
CAS:Produto Controlado<p>Impurity Bumetanide Impurity<br>Applications Bumetanide 3-(Butyl(nitroso)amino) is an impurity of Bumetanide(B689550). Bumetanide is a diuretic.<br>References Ward, A., et al.: Drugs, 28, 426 (1984), Gradeen, C.Y, et al.: J. Anal. Toxicol., 14, 123 (1990), Tata, P.N.V., et al.: Anal. Profiles Drug Subs. Excip., 22, 107 (1993),<br></p>Fórmula:C17H19N3O6SCor e Forma:NeatPeso molecular:393.41(±)-Ibuprofen Methyl Ester
CAS:Produto Controlado<p>Applications (±)-Ibuprofen Methyl Ester is a phototoxic, photoproduct of Ibuprofen (I140000), a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen is also used as an anti-inflammatory drug.<br>References Miranda, M.A., et. al.: Toxicol. In Vitro, 5, 451 (1991); Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Fórmula:C14H20O2Cor e Forma:ColourlessPeso molecular:220.315-Aminosalicylic Acid-13C6 Hydrochloride (Mesalazine-13C6 Hydrochloride)
CAS:Produto ControladoFórmula:C13C6H7NO3·HClCor e Forma:NeatPeso molecular:195.55Quininone
CAS:<p>Applications Quininone has been shown to have antimalarial activity in mice. Quininone has been shown to aid the binding of drug-induced antibodies to human platelets.<br>References Klayman, D.L., et. al.: J. Med. Chem., 16, 1042 (1973); Christie, D.J., et. al.: J. Lab. Clin. Med., 104, 730 (1984)<br></p>Fórmula:C20H22N2O2Cor e Forma:White To Light BeigePeso molecular:322.40Acetaminophen (1 mg/mL in Methanol)
CAS:Produto ControladoFórmula:C8H9NO2Cor e Forma:Single SolutionPeso molecular:151.16Aceclofenac Ethyl Ester
CAS:Produto Controlado<p>Impurity Aceclofenac EP Impurity E<br>Applications Aceclofenac Ethyl Ester is a 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative used as an anti-inflammmatory and analgesic agent. Aceclofenac EP Impurity E.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yscla, A., et al.: Drugs Exp. Clin. Res., 14, 491 (1988), Ballesteros, R., et al.: Clin. Trials J., 27, 12 (1990)<br></p>Fórmula:C18H17Cl2NO4Cor e Forma:White To Light YellowPeso molecular:382.246-Hydroxy Etodolac
CAS:Produto Controlado<p>Applications 6-Hydroxy Etodolac is an Etodolac (E933100) metabolite.<br>References Humber, L., et al.: J. Med. Chem., 32, 2582 (1989), Koupai-Abyazani, M., et al.: J. Anal. Toxicol., 23, 200 (1999),<br></p>Fórmula:C17H21NO4Cor e Forma:NeatPeso molecular:303.353-(N-Acetyl-L-cystein-S-yl) Acetaminophen
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Paracetamol Mercapturate is a metabolite of Acetaminophen (A161220) (1,2). Acetaminophen is a widely used analgesic and antipyretic drug. It can also be used in biological study of urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation.<br>References (1) Trettin, A., et al.: J. Chromatogr. B., 963, 105 (2014) (2) Pickering, G., et al.: Clin. Pharmacol. Ther., 90, 707 (2011)<br></p>Fórmula:C13H16N2O5SCor e Forma:NeatPeso molecular:312.342,4-Disulfamyl-5-trifluoromethylaniline
CAS:Fórmula:C7H8F3N3O4S2Cor e Forma:White To Off-WhitePeso molecular:319.28Oxyclozanide
CAS:<p>Applications Oxyclozanide, an anthelmintic drug displays strong in vivo and vitro activity against methicillin resistant S. aureus and Gram-positive bacteria Enterococcus faecium.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rajamuthiah, R., et al.: PLOS ONE, 10, 1-19 (2015)<br></p>Fórmula:C13H6Cl5NO3Cor e Forma:NeatPeso molecular:401.464-Isobutylbenzoic Acid
CAS:<p>Applications 4-Isobutylbenzoic Acid is used in the studies for the identification of the degradation products and potential impurities in Ibuprofen. 4-Isobutylbenzoic Acid is also applied in the determination of related substances in dexibuprofen using HPLC.<br>References Dondoni, A., et al.: Farmaco, Edizione Pratica, 41, 237 (1986); Xie, L., et al.: Zhongguo Yaoshi, 19, 1088 (2016)<br></p>Fórmula:C11H14O2Cor e Forma:NeatPeso molecular:178.23(-)-(3S)-3-Hydroxy Quinine
CAS:Produto ControladoFórmula:C20H24N2O3Cor e Forma:NeatPeso molecular:340.42Triflusulfuron-methyl
CAS:Produto Controlado<p>Applications Triflusulfuron-methyl, is a widely used sulfonylurea herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, N., et al.: Huanjing Kexue, 33, 4400 (2012);<br></p>Fórmula:C17H19F3N6O6SCor e Forma:WhitePeso molecular:492.43Acetaminophen Dimer-d6
CAS:Produto Controlado<p>Applications Acetaminophen Dimer-d6 is deuterium labeled Acetaminophen Dimer (A161235). Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)(3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Fórmula:C16H10D6N2O4Cor e Forma:NeatPeso molecular:306.35O,O-Di-2-Naphthalenyl Ester Carbonothioic Acid
CAS:Fórmula:C21H14O2SCor e Forma:NeatPeso molecular:330.4
