Sulfonamidas e Derivados

<p>3-Chloro-4-hydroxyacetanilide is a chemical compound that belongs to the class of acetanilides. It has long-term toxicity and is used as a drug substance in the production of aniline derivatives. 3-Chloro-4-hydroxyacetanilide has been shown to be carcinogenic in hamsters. The long term exposure to this chemical was shown to cause liver damage and increased incidence of tumours in rats. This drug also contains impurities and traces of chloride, chlorine, and thionyl chloride, which are toxic substances that can cause irritation or burns on contact with skin or eyes.</p>

<p>Foramsulfuron is a potent ALS inhibitor and herbicide that inhibits plant growth, primarily targeting grass and broadleaf weeds in corn fields.</p>

<p>Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性，具有额外的镇痛、解热和胃保护特性。</p>

<p>Vaborbactam (RPX7009) is a β-lactamase inhibitor that is often used in conjunction with meropenem to study pneumonia and CRE infections.</p>

<p>Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR).</p>

<p>Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75).</p>

<p>Bromfenac Related Compound A is a chemical impurity, which is often encountered during the synthesis and formulation of bromfenac, a non-steroidal anti-inflammatory drug (NSAID). This compound arises as a byproduct in the chemical synthetic pathway utilized in the production of bromfenac, necessitating stringent analytical methods to ensure product purity and compliance with pharmaceutical standards.The mode of action for Bromfenac Related Compound A itself is not typically characterized, as it is primarily the parent compound, bromfenac, that is pharmacologically active. Bromfenac works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2) that mediate inflammatory processes. However, the related compound is investigated to understand the synthesis intricacies and to refine processes that limit its formation.Understanding and controlling the levels of Bromfenac Related Compound A is crucial in pharmaceutical applications, as the presence of impurities can affect the efficacy, safety, and overall quality of the drug product. Analytical chemists and pharmaceutical scientists study this compound extensively using chromatographic and spectroscopic techniques to ensure drug safety and compliance with regulatory guidelines.</p>

<p>Tribenuron, a slow acting sulfonylurea herbicide, controls broadleaf weed.</p>