APIs para pesquisa e impurezas

4-Phenybutyl 2-carboxyethylphosphinic acid is used as an analytical standard and has been shown to be a metabolite of other drugs. It is also used as an impurity standard for HPLC, and provides a niche for drug product development.

N-Des[2-(1-methyl-2-pyrrolidinyl)ethyl] udenafil is an impurity in the drug product. It is a synthetic compound and is a metabolite of the drug product. N-Des[2-(1-methyl-2-pyrrolidinyl)ethyl] udenafil is present as a byproduct of the metabolism of the active ingredient. The CAS number for this substance is 319491-68-4. This impurity has been observed to have niche applications in research and development and analytical studies. It has also been found to be pharmacopoeia grade, which means it meets or exceeds purity standards set by regulatory authorities.

Solifenacin N-oxide is an anti-cholinergic agent that has been shown to be effective in the treatment of overactive bladder. Solifenacin N-oxide is a prodrug that is hydrolyzed in vivo to solifenacin, its active form. The compound reversibly binds to muscarinic receptors and inhibits the release of acetylcholine. Solifenacin N-oxide has been shown to have low levels of impurities and is highly soluble in water. It was also found to be stable when stored at room temperature for two months. This drug has a high flow rate and moderate retention time, which makes it suitable for reversed-phase liquid chromatography (RPLC). RPLC is a chromatographic technique that separates compounds by size, hydrophobicity, or charge.

(5S)-5-(Aminomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-1,3-oxazolidin-2-one is a molecule with a broad spectrum of antimicrobial activity. It is a potent inhibitor of the enzyme metallo-β-lactamase, which is found in Streptococcus faecalis and other bacteria. This molecule also has antibacterial activity against Streptococcus pyogenes and Staphylococcus aureus. (5S)-5-(Aminomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-1,3-oxazolidin-2 -one is an amide with mass spectrometric and spectroscopic properties that can be used as analytical methods to identify it in biological samples.

Mikimopine is a kinase inhibitor that has shown promising results in the treatment of cancer. It works by inhibiting specific proteins involved in cancer cell growth and survival, leading to apoptosis (cell death) of tumor cells. Mikimopine is an analog of a naturally occurring protein found in human urine and Chinese medicinal herbs. It specifically targets cyclin-dependent kinases, which are enzymes that regulate cell division and proliferation. This drug has shown potent anticancer activity both in vitro and in vivo, making it a promising candidate for further development as an anticancer agent. Its selectivity towards cancer cells makes it a potentially effective therapy with minimal side effects compared to traditional chemotherapy treatments.

Acetylazide is an analog of a compound found in human urine that has shown promising anticancer activity. It is a potent inhibitor of protein kinases, which are enzymes involved in the regulation of cell growth and division. Acetylazide has been shown to induce apoptosis (cell death) in cancer cells, particularly those associated with thyroid cancer. This compound has also been tested in Chinese hamster ovary cells and has demonstrated a high degree of selectivity for tumor cells over normal cells. Acetylazide may be a promising candidate for the development of new anticancer drugs.

Desgadolinium gadoteridol is a contrast agent that is used in magnetic resonance imaging (MRI). It is a gadolinium-based contrast agent that contains an ester linkage. The chelate complex of gadolinium with desgadolinium has been shown to have high water permeability and target tissue affinity, as well as low toxicity. Desgadolinium gadoteridol is used to diagnose inflammatory bowel diseases by determining the thickness of the bowel wall. This agent may also be used to evaluate blood pressure and diagnose hemorrhoids or colorectal polyps.

1,3-bis(1,1-Dimethylpropyl) benzene is a synthetic compound that is used in drug product formulation. It is also used as an analytical standard for the determination of 1,3-bis(1,1-dimethylethyl)benzene in drug products and as a natural impurity in API preparations. This compound is metabolized to 1,3-dibromobenzene and 1,2-dibromoethane during its metabolic process. The chemical properties of this compound are similar to those of other alkylbenzenes and it has been shown to have pharmacological effects such as analgesic and antiinflammatory activities.

Deterenol acetate is a drug product that is used as an analytical standard. It has been shown to be a natural metabolite of the synthetic drug deterenoic acid, which is an impurity in API preparations of the drug. Deterenol acetate has been shown to have anti-inflammatory effects and may be useful for treating cardiovascular disease, cancer, and arthritis. Deterenol acetate has also been shown to have potential as a treatment for high blood pressure.

Ethosuximide impurity A is a fluorinated compound that inhibits the enzyme acetylcholinesterase. It has been shown to inhibit the catalytic mechanism of acetylcholinesterase, which leads to its inhibitory effect on the enzyme. The compound does not have any structural similarity to the other known inhibitors of this enzyme. Ethosuximide impurity A has been shown to be an antimutagen and anticarcinogen in vitro, with a postulated mechanism of action that involves inhibition of a water molecule from binding to the active site.

Δ2-Cefuroxime is a prodrug that is hydrolyzed in vivo to cefuroxime, its active form. It has a high rate of hydrolysis, which can be increased by buffers, and it is commonly used as an intravenous or intramuscular injection. Δ2-Cefuroxime has two isomeric forms: the cis-isomer and trans-isomer. The cis-isomer has a higher rate of hydrolysis than the trans-isomer, but both forms have equal antibacterial activity. In addition, Δ2-cefuroxime can be converted into erythromycin.

(betaR,deltaR)-2,3-Bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemicalcium salt is an impurity that is used in the production of a drug product. This product is metabolized to (betaR,deltaR)-2,3-bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole 1 heptanoic acid which is used as an analytical standard for HPLC.

Surfactin is a cyclic lipopeptide that has been found in urine and has shown potential as an anticancer agent. It has been shown to inhibit kinases, including indirubin and Chinese hamster ovary cell tumor kinase, which are involved in cancer cell proliferation. Surfactin analogs have also been developed as inhibitors of cancer cell growth and inducers of apoptosis. In addition to its anticancer properties, surfactin has been found to have antimicrobial activity against a variety of bacteria, including Clostridium perfringens. Overall, surfactin shows promise as a multifunctional therapeutic agent with potential applications in both cancer treatment and microbial control.

Paritaprevir is a medicinal compound that acts as an inhibitor of protein kinases. It has been shown to be effective against various types of cancer cells, including those found in the urine and tumors. Paritaprevir is an analog of a Chinese anticancer compound and has been shown to induce apoptosis in human cancer cells. This potent kinase inhibitor selectively targets specific kinases involved in cancer cell proliferation, making it a promising candidate for the treatment of cancer. Its ability to inhibit kinases also makes it an attractive therapeutic option for other diseases that involve aberrant kinase activity.

Acarbose EP Impurity D is a polymerase chain reaction (PCR) product that is produced by the subtilis, which is a bacterium. Acarbose EP Impurity D has been shown to inhibit the growth of viruses and bacteria in vitro. It inhibits the synthesis of bioactive molecules by inhibiting the activity of cellular enzymes, such as polymerase chain reaction products. Acarbose EP Impurity D also inhibits viral replication and has been shown to have an inhibitory effect on HIV-1 protease.

L-693,403 Maleate is an analytical and research chemical with a purity of > 99%. L-693,403 Maleate is used as an impurity standard for HPLC analysis and drug development. It can also be used as a reference standard in the production of APIs. L-693,403 Maleate is an impurity in the synthesis of several drugs, including clozapine, fluoxetine, and loratadine. The natural form of L-693,403 Maleate can be found in the leaves of the plant Acacia holosericea. Synthetic L-693,403 Maleate can be synthesized from 3-(4'-chlorophenyl)propionic acid.

1-(3'-Pyridylmethyl)-3-(4'-nitrophenyl)urea is a medicinal compound that has been used in Chinese traditional medicine for its tumor-fighting properties. It acts as a potent inhibitor of protein kinases, which are enzymes involved in cell signaling and proliferation. This analog has been shown to induce apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of specific kinases. The compound has also demonstrated anticancer activity in human cancer cell lines and may have potential as a therapeutic agent for the treatment of various types of cancer. Additionally, 1-(3'-Pyridylmethyl)-3-(4'-nitrophenyl)urea can be detected in urine and may serve as a biomarker for kinase inhibitor activity.

(-)-Nefopam is a medicinal compound that acts as an inhibitor of kinases, which are enzymes involved in many cellular processes. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, or programmed cell death. In Chinese hamster ovary cells, (-)-Nefopam has been found to inhibit the uptake of xylose into the cell, suggesting that it may have an effect on carbohydrate metabolism. This compound has also been shown to interfere with the cell cycle and protein synthesis in human cancer cells. Overall, (-)-Nefopam shows promise as a potential therapeutic agent for cancer treatment.

Please enquire for more information about rac Clavam-2-carboxylic acid sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Descyano febuxostat ethyl ester is a synthetic, natural, and API impurity. 3-Descyano febuxostat ethyl ester is used as an analytical standard in drug development. It is also used as a custom synthesis, impurity standard and analytical reference material.

R401553 is a potent protein kinase inhibitor that has been shown to induce apoptosis and arrest the cell cycle in various human cancer cell lines. It belongs to the class of indole derivatives and has been found to be particularly effective against leukemia and tumor cells. R401553 selectively inhibits kinases that are involved in cell proliferation, survival, and angiogenesis. This inhibitor has been tested on Chinese hamster ovary (CHO) cells and human cancer cell lines, showing promising results in inhibiting tumor growth. R401553 may have potential as a therapeutic agent for the treatment of various cancers.

Please enquire for more information about 1-[2,3,4-Tris(methoxymethoxy)phenyl]-ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Tris(trifluoroacetoxy)iodine is an analog of iodine that has shown promise as an anticancer agent. It works by inhibiting kinase activity, which can disrupt the cell cycle and lead to apoptosis in cancer cells. Tris(trifluoroacetoxy)iodine has been found to be effective against a variety of human cancer cell lines, including those resistant to other anticancer agents. In addition, it has been shown to inhibit elastase activity and may have potential as an inhibitor of protein degradation in cancer cells. Overall, Tris(trifluoroacetoxy)iodine holds great potential as a new class of anticancer inhibitors with promising results for tumor treatment.

11-Hydroxyasenapine is a drug that has been developed for the treatment of schizophrenia and Parkinson's disease. It is metabolized to 11-hydroxysenapine, which has an affinity for dopamine receptors. It is a high purity API with a purity of 98.6%. This product is available as an HPLC standard or impurity standard.

Please enquire for more information about 4-[(3-Chlorophenyl)sulfonyl]benzenamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Hydroxy warfarin β-D-glucuronide disodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Melatonin methoxy-d3 is a synthetic melatonin metabolite that is used as an impurity standard in the manufacture of drug products. It is also used as a research and development intermediate, a custom synthesis, or a raw material in the production of other drugs. Melatonin methoxy-d3 has CAS Number 60418-64-6 and its chemical name is 3-[2-(Methoxymethyl)benzofuran-5-yl]oxyindole. Melatonin methoxy-d3 is a synthetic drug product with high purity and pharmacopoeia grade. It has been shown to be effective in metabolism studies and to have niche applications for analytical work.

((E)-5-((M-[(2-Carboxyethyl)carbamoyl]phenyl)azo)-2-salicylic acid) is a drug product. It is a synthetic, white to off-white powder that has a molecular weight of 246.9 g/mol and an assay of 99%. The impurity standard for this product is (E)-5-(4-(methylsulfonyl)phenylazo)-2-salicylic acid.

Please enquire for more information about 13-Chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,9,11,13-heptaene including the price, delivery time and more detailed product information at the technical inquiry form on this page