APIs para pesquisa e impurezas
Subcategorias de "APIs para pesquisa e impurezas"
- Aminoácidos e Derivados(12.332 produtos)
- Antraquinonas e Derivados(404 produtos)
- Derivados de Benzimidazol e Imidazol(10.440 produtos)
- Derivados das Benzodiazepinas(333 produtos)
- Carboidratos e Glicoconjugados(5.048 produtos)
- Ésteres e Derivados(42.250 produtos)
- Ácidos Graxos e Derivados Lipídicos(32.410 produtos)
- Flavonoides e Polifenóis(17.082 produtos)
- Radicais Livres e Agentes Oxidantes/Redutores(213 produtos)
- Cetonas e Derivados(2.400 produtos)
- Antibióticos Naturais e Semissintéticos(6.379 produtos)
- Nitrilas e Derivados Ciano(3.068 produtos)
- Nitrosaminas e Derivados(55 produtos)
- Nucleosídeos e Nucleotídeos(3.475 produtos)
- Fosfatos e Fosfonatos Orgânicos(1.200 produtos)
- Sulfonatos e Sulfatos Orgânicos(10.431 produtos)
- Compostos Organometálicos(4.421 produtos)
- Outros(6.302 produtos)
- Peptídeos e Proteínas(3.146 produtos)
- Polímeros e Derivados(100 produtos)
- Derivados de Purinas e Pirimidinas(8.946 produtos)
- Derivados de Quinazolina e Quinolina(66.005 produtos)
- Quinonas e Derivados(24.359 produtos)
- Sais e Derivados de API(80.604 produtos)
- Esteroides e Derivados(4.953 produtos)
- Sulfonamidas e Derivados(2.592 produtos)
- Terpenoides e Derivados(3.847 produtos)
- Tiazolidinedionas e Tiopiranos(2.753 produtos)
- Compostos β-Adrenérgicos(231 produtos)
Foram encontrados 57909 produtos de "APIs para pesquisa e impurezas"
1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyl-1-propanone
CAS:1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyl-1-propanone is a metabolite that is formed from the drug product. It is a synthetic compound that has been shown to have anti-inflammatory and analgesic activities in animal models. 1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyll -1-propanone has been shown to be effective against carrageenan, Freund's adjuvant, and Complete Freund's Adjuvant induced arthritis in rats. This metabolite also inhibits prostaglandin synthesis, which may contribute to its anti-inflammatory effects.Fórmula:C18H20O4Pureza:Min. 95%Peso molecular:300.35 g/molDesphenol 1-hydroxyethyl cefoperazone furolactone
CAS:Please enquire for more information about Desphenol 1-hydroxyethyl cefoperazone furolactone including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C20H25N5O9SPureza:Min. 95%Peso molecular:511.5 g/molBIM 23127
CAS:BIM 23127 is a protein kinase inhibitor that acts as an analog of vitamin K. It has been shown to have anticancer effects by inducing apoptosis in cancer cells. BIM 23127 inhibits the activity of kinases, which are enzymes that regulate cell growth and division. This inhibition leads to a decrease in tumor growth and may be useful in the treatment of various types of cancer. BIM 23127 has been tested in Chinese hamster ovary cells and human urine, showing promising results as a potential anticancer agent. Its ability to specifically target cancer cells while sparing healthy cells makes it a desirable option for cancer treatment.
Fórmula:C62H71N11O9S2Pureza:Min. 95%Peso molecular:1,178.4 g/molBIM 23052
CAS:BIM 23052 is an analog kinase inhibitor that has been shown to have potent anticancer activity. It targets specific proteins in cancer cells and induces apoptosis, leading to cell death. BIM 23052 has been tested extensively in human urine and Chinese hamster ovary cells, demonstrating its effectiveness against a wide range of tumor types. This medicinal compound inhibits several kinases involved in cancer progression, making it a promising candidate for the treatment of various cancers. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.Fórmula:C61H75N11O10Pureza:Min. 95%Peso molecular:1,122.3 g/mol3-Carboxy-4-chloro-benzenediazonium chloride
CAS:Please enquire for more information about 3-Carboxy-4-chloro-benzenediazonium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C7H4Cl2N2O2Pureza:Min. 95%Peso molecular:219.02 g/molN,N’-Bis(2’-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine
CAS:N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is a drug product that is used as an HPLC standard. It has CAS No. 1618644-29-3 and a molecular mass of 309.35 g/mol. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is an impurity in the synthesis of pyridostigmine bromide and is found in the urine of mice treated with this drug. This impurity can be determined by GC/MS and LC/MS techniques. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is also found as a metabolite in rats and humans as well as being an analytical reference material for API impurities. The metabolite may be formedFórmula:C20H13ClN4O2Pureza:Min. 95%Peso molecular:376.8 g/mol5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one
CAS:5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one is a synthetic compound that has been used as an impurity standard. This substance is also found in the drug product Loxapine (Loxitane) and is metabolized to the active ingredient loxapine. 5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one has not been shown to have any therapeutic effects.Fórmula:C14H10N2O2Pureza:Min. 95%Peso molecular:238.24 g/mol(3R)-3-Amino-2,3-dihydro-1H-inden-1-one hydrochloride
CAS:Please enquire for more information about (3R)-3-Amino-2,3-dihydro-1H-inden-1-one hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C9H10ClNOPureza:Min. 95%Peso molecular:183.63 g/mol(Nitrosoimino)bisacetic acid diethyl ester
CAS:Please enquire for more information about (Nitrosoimino)bisacetic acid diethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C8H14N2O5Pureza:Min. 95%Peso molecular:218.21 g/mol3alpha-Hydroxy pravastatin sodium salt
CAS:3alpha-Hydroxy pravastatin sodium salt is a white to off-white crystalline powder. It is used as an analytical standard for 3alpha-hydroxypravastatin and its metabolites. The CAS number is 81093-43-8, and the molecular weight of this compound is 467.6 g/mol. This product can be custom synthesized to meet your needs.Fórmula:C23H35NaO7Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:446.51 g/molCarbidopa Impurity 2
CAS:Produto ControladoCarbidopa Impurity 2 is an impurity of carbidopa, a drug product that is used to treat Parkinson's disease. Carbidopa Impurity 2 is an analytical standard for the identification and quantification of carbidopa in biological samples. The natural form of this compound is unknown, but it has been synthesized using custom synthesis techniques. This compound was also used to develop a high purity HPLC standard and as a pharmacopoeia reference material.
Fórmula:C11H16N2O4Pureza:Min. 95%Peso molecular:240.26 g/molN,N-Dimethyl-2-[(3-methylphenyl)phenylmethoxy]ethanamine
CAS:Produto ControladoN,N-dimethyl-2-[(3-methylphenyl)phenylmethoxy]ethanamine is a metabolite of amphetamine. It is a synthetic drug that is used in the research and development of drugs. Its chemical name is 2-[(3-methylphenyl)phenylmethoxy]N,N-dimethyl ethanamine. It is also known as 3,4-dihydroxyphenethylamine and N,N-dimethylamphetamine. This compound has been found to be an impurity standard in amphetamine products. The CAS number for this compound is 21945-86-8.Fórmula:C18H23NOPureza:Min. 95%Cor e Forma:PowderPeso molecular:269.4 g/mol(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
CAS:Please enquire for more information about (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C16H12F6N4OPureza:Min. 95%Peso molecular:390.28 g/mol1,3-bis(1,1-Dimethylpropyl) benzene
CAS:1,3-bis(1,1-Dimethylpropyl) benzene is a synthetic compound that is used in drug product formulation. It is also used as an analytical standard for the determination of 1,3-bis(1,1-dimethylethyl)benzene in drug products and as a natural impurity in API preparations. This compound is metabolized to 1,3-dibromobenzene and 1,2-dibromoethane during its metabolic process. The chemical properties of this compound are similar to those of other alkylbenzenes and it has been shown to have pharmacological effects such as analgesic and antiinflammatory activities.
Fórmula:C16H26Pureza:Min. 95%Peso molecular:218.38 g/mol1-Hydroxy pioglitazone hydrochloride
CAS:Pioglitazone is a thiazolidinedione antidiabetic agent that is used to treat type 2 diabetes. Pioglitazone has been shown to have the potential to attenuate insulin resistance and decrease hepatic glucose output. Pioglitazone has also been shown to inhibit many of the enzymes involved in the metabolism of glucose, such as glucokinase, phosphoenolpyruvate carboxykinase, and pyruvate dehydrogenase. In addition, pioglitazone has been shown to increase insulin sensitivity by increasing the number of insulin receptors on cell membranes. Pioglitazone has also been shown to reduce blood pressure through its effects on erythropoietin activity and nitric oxide production. This drug may act as an antioxidant by inhibiting peroxidation of lipids in the liver. Pioglitazone has also been studied for its effect on nervous system diseases, such as Alzheimer's disease and XFórmula:C19H21ClN2O4SPureza:Min. 95%Peso molecular:408.9 g/mol5'-O-Acetyl ribavirin
CAS:Produto Controlado5'-O-Acetyl ribavirin is an impurity of ribavirin, a drug product that belongs to the group of antiviral drugs. It is used in the treatment of chronic hepatitis C and influenza. 5'-O-Acetyl ribavirin is found in natural products such as plants, honey, and wine. The CAS number for this impurity is 58151-87-4. This compound can be synthesized through custom synthesis or by using a high purity HPLC standard as an impurity standard.Fórmula:C10H14N4O6Pureza:Min. 95%Peso molecular:286.24 g/mol(R)-Imazamox
CAS:(R)-Imazamox is a medicinal compound that acts as a potent protein kinase inhibitor. It has been shown to be effective in the treatment of various types of cancer, including leukemia, by inducing apoptosis and inhibiting tumor cell growth. (R)-Imazamox specifically targets the cell cycle of cancer cells, preventing them from dividing and multiplying. It has also been found to have anti-inflammatory properties and is being studied for its potential use in treating inflammatory diseases such as arthritis. Chinese herbal medicine has long recognized the benefits of (R)-Imazamox, using it in traditional remedies to treat urinary issues and other ailments. Overall, (R)-Imazamox is a highly effective anticancer agent with promising potential for future medical applications.Fórmula:C15H19N3O4Pureza:Min. 95%Peso molecular:305.33 g/molAcetylazide
CAS:Acetylazide is an analog of a compound found in human urine that has shown promising anticancer activity. It is a potent inhibitor of protein kinases, which are enzymes involved in the regulation of cell growth and division. Acetylazide has been shown to induce apoptosis (cell death) in cancer cells, particularly those associated with thyroid cancer. This compound has also been tested in Chinese hamster ovary cells and has demonstrated a high degree of selectivity for tumor cells over normal cells. Acetylazide may be a promising candidate for the development of new anticancer drugs.
Fórmula:C13H14N4O4SPureza:Min. 95%Peso molecular:322.34 g/molrac-3-Deacetyl-3-butanoyl acebutolol hydrochloride
CAS:3-Deacetyl-3-butanoyl acebutolol hydrochloride is a racemic mixture of two enantiomers, (+)-(S)-3-Deacetyl-3-butanoyl acebutolol and (-)-(R)-3-Deacetyl-3-butanoyl acebutolol. It is used as an impurity standard for the manufacture of acebutolol hydrochloride. The substance has a purity of at least 99% by HPLC. 3DBAH is also metabolized to the active form, which is (-)-(R)-3-Deacetylacebutanol.Fórmula:C20H33ClN2O4Pureza:Min. 95%Peso molecular:400.94 g/molDeterenol acetate
CAS:Produto ControladoDeterenol acetate is a drug product that is used as an analytical standard. It has been shown to be a natural metabolite of the synthetic drug deterenoic acid, which is an impurity in API preparations of the drug. Deterenol acetate has been shown to have anti-inflammatory effects and may be useful for treating cardiovascular disease, cancer, and arthritis. Deterenol acetate has also been shown to have potential as a treatment for high blood pressure.
Fórmula:C13H21NO4Pureza:Min. 95%Peso molecular:255.31 g/molMontelukast dicarboxylic acid
CAS:Produto ControladoMontelukast is a drug product that belongs to the class of drugs called leukotriene receptor antagonists. Montelukast binds to cysteinyl leukotrienes (LTC4, LTD4, LTE4) and prevents their interaction with receptors on the cell surface. It can be used for the treatment of asthma, chronic obstructive pulmonary disease, and other allergic conditions. Montelukast is available in tablet form and is taken orally. Montelukast is not expected to be toxic because it has been shown to have a low incidence of side effects in clinical trials.Fórmula:C35H34ClNO5SPureza:Min. 95%Peso molecular:616.20 g/mol(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-{[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl} acetamide dihydrochloride - >80%, Mixture of Diastereomers
(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl} acetamide dihydrochloride is a drug product with purity of >80%. It is a mixture of diastereomers. The impurities are not detected by HPLC. This compound is used in the development of drugs. Its metabolite is also available to purchase.Fórmula:C13H15N5O4S2·2HClPureza:Min. 95%Peso molecular:442.34 g/molN,N-Dimethylglycylamido-minocycline dihydrochloride
CAS:N,N-Dimethylglycylamido-minocycline dihydrochloride is a medicinal compound that is used as an inhibitor of protein kinases in cancer research. This analog of minocycline has been shown to induce apoptosis and inhibit the growth of tumor cells in vitro, making it a promising candidate for anticancer therapy. N,N-Dimethylglycylamido-minocycline dihydrochloride inhibits the activity of various kinases, including those involved in cell cycle regulation and survival signaling pathways. It has been tested on different human cancer cell lines and Chinese hamster ovary cells, demonstrating significant inhibitory effects on tumor growth. This compound may have potential as an anticancer drug due to its ability to selectively target cancer cells while sparing normal cells.Fórmula:C27H35N5O8Pureza:Min. 95%Peso molecular:557.6 g/molImpurity G
Impurity G is an impurity found in the drug Iohexol. It is a synthetic, amide, propylamine, diacetate and methyl anthranilate. Impurity G has been shown to be a catalyst for the production of iodinated contrast media with high yield. This can be used to make the drug Moxifloxacin hydrochloride, which is used to treat bacterial infections such as pneumonia and bronchitis caused by Legionella pneumophila or Mycoplasma pneumoniae. The chemical compound moxifloxacin has anti-inflammatory properties that are due to its ability to inhibit prostaglandin synthesis.Pureza:Min. 95%N-Formyl-D-leucine (1R)-1-[[(2R,3R)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester
CAS:N-Formyl-D-leucine (1R)-1-[[(2R,3R)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester is a synthetic metabolite that is used as an impurity standard for the analysis of N-formylmetabolites in drugs. It is also used to study the metabolism of drugs. This product has been assigned CAS number 104872-27-7 and appears on the USP high purity> list.Fórmula:C29H53NO5Pureza:Min. 95%Peso molecular:495.73 g/molBenz[A]anthracene-7-acetonitrile
CAS:Please enquire for more information about Benz[A]anthracene-7-acetonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C20H13NPureza:Min. 95%Peso molecular:267.3 g/molDesoxo-palbociclib
CAS:Desoxo-palbociclib is a drug product that has been custom synthesized. The purity of this compound is high, with analytical results that meet the pharmacopoeia standards for purity. Metabolism studies have been conducted to determine the natural and synthetic metabolites of this compound. Desoxo-palbociclib is also in Phase II clinical trials for drug development, which are expected to be completed by 2020. There are no known impurities, but there may be traces of other compounds due to its synthetic nature.Fórmula:C24H29N7OPureza:Min. 95%Peso molecular:431.5 g/molPaliperidone Z-oxime
CAS:Paliperidone Z-oxime is a metabolite of paliperidone that is used as an impurity standard. It is a white crystalline powder with a molecular weight of 437.2 g/mol. Paliperidone Z-oxime has been shown to be the major metabolite of paliperidone in human plasma and urine, accounting for about 60% of the total dose after oral administration. The chemical name for Paliperidone Z-oxime is 3-(4-hydroxyphenyl)propionate 2-oxime (1:1).Fórmula:C23H28F2N4O3Pureza:Min. 95%Peso molecular:446.5 g/molAzilsartan Dimer
CAS:Azilsartan Dimer is a crystalline solid with a melting point of 95-98°C. It is insoluble in water and soluble in acetone, acetonitrile, and dimethyl sulfoxide. Azilsartan Dimer has shown antihypertensive effects in animal models. The chemical structure of Azilsartan Dimer is based on the alkyl ester of azilsartan and an acetone solvent.
Fórmula:C35H28N4O11Pureza:Min. 95%Peso molecular:680.62 g/molFlutianil
CAS:Flutianil is an analog of a medicinal compound that has been shown to have potent anticancer activity. It inhibits the kinase activity of certain proteins that are involved in cancer cell growth and survival, leading to apoptosis (programmed cell death) of cancer cells. Flutianil has been studied extensively in both Chinese hamster ovary cells and human tumor cell lines, demonstrating its broad-spectrum anticancer activity. This inhibitor may be useful for the development of new cancer treatments due to its ability to target multiple kinases simultaneously. Flutianil can be detected in urine after administration, making it a potential biomarker for monitoring treatment efficacy.Fórmula:C19H14F4N2OS2Pureza:Min. 95%Peso molecular:426.5 g/molProcyanidin B2 3,3'-di-o-gallate
CAS:Procyanidin B2 3,3'-di-o-gallate (PB2DOG) is a gallotannin that can be found in the leaves of the dogwood tree. It has dose-dependent effects on the serine protease activity of butanol, which is used as a model for pancreatic lipase. PB2DOG also inhibits the activity of viruses such as hepatitis C and herpes simplex virus type 1, and cancer cells such as du145 and japonica. PB2DOG has been shown to induce apoptosis in cancer cells by reducing DNA synthesis and inhibiting protein synthesis. The mechanism behind this effect is not fully understood, but it may be related to its ability to inhibit cCAAT/enhancer binding protein (C/EBP), an important transcription factor for cell proliferation.Fórmula:C44H34O20Pureza:Min. 95%Peso molecular:882.7 g/mol13-Chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,9,11,13-heptaene
CAS:Please enquire for more information about 13-Chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,9,11,13-heptaene including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C19H17ClN2Pureza:Min. 95%Peso molecular:308.8 g/mol3,5-Bis[2-[[[2-[(aminoiminomethyl)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-4H-1,2,4,6-thiatriazine-1,1-dioxide
CAS:Famotidine is a pharmaceutical agent that belongs to the class of H2-receptor antagonists. It is used for the treatment of peptic ulcers and gastroesophageal reflux disease. Famotidine inhibits gastric acid secretion by blocking the H2-receptors in the parietal cells in the stomach. There are two major impurities, 4-amino-N-[(4-[[[2-(aminosulphonyl)thiazol-4-yl]methyl]sulphanyl]ethyl]-3,5-bis[[2-[(aminoiminomethyl)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-1,2,4,6-thiatriazine 1,1 dioxide and 2-[(aminoiminomethyl)amino]-N-[(4-[[2-(aminosulphonyl)thiazol-4-ylFórmula:C16H23N11O2S5Pureza:Min. 95%Peso molecular:561.76 g/molBrexpiprazole impurity 3
CAS:Brexpiprazole impurity 3 is a drug product that has been custom synthesized for research purposes. The purity of this product is high and it has been analyzed using analytical methods. This product can be used to study the metabolism of brexpiprazole, which is an atypical antipsychotic medication. Brexpiprazole impurity 3 also has pharmacopoeia standards, which can be used to develop new drugs or as a quality control standard in research and development.Fórmula:C25H27N3O3SPureza:Min. 95%Peso molecular:449.57 g/molCarbidopa impurity F
CAS:Produto ControladoCarbidopa is an impurity of the drug L-DOPA, which is used as a treatment for Parkinson's disease. Carbidopa is a prodrug that is converted to L-DOPA by decarboxylase, an enzyme in the body. The conversion process can be inhibited by the presence of carbidopa impurity F (CIF), which binds to carboxamides and forms a stable complex with them. This prevents CIF from binding to decarboxylase and blocking its ability to convert carbidopa into L-DOPA. CIF has been shown to have anti-parkinsonian effects by reducing the severity of symptoms associated with Parkinson's disease such as muscular rigidity and tremors.Fórmula:C12H18N2O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:254.28 g/mol9-Hydroxy propantheline bromide
CAS:Please enquire for more information about 9-Hydroxy propantheline bromide including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C23H30BrNO4Pureza:Min. 95%Peso molecular:464.4 g/molOxolamine citrate salt
CAS:Oxolamine citrate salt is a pharmaceutical drug used for the treatment of scleroderma. It acts as an iron chelator and inhibits the production of the cytotoxic agent, podophyllotoxin, by inhibiting its conversion to epipodophyllotoxin. Oxolamine citrate salt has been shown to have a beneficial effect on Alzheimer's disease and may have therapeutic potential in other neurological diseases such as Parkinson's disease. The compound has been shown to inhibit acetonitrile-induced hyperactivity in mice. Oxolamine citrate salt has also been found to be effective against Pseudomonas aeruginosa and Staphylococcus aureus isolates that are resistant to oxacillin, ginkgetin, or pseudoephedrine. This drug can be analyzed using liquid chromatography with an acetonitrile gradient and a hypersil C18 column.Fórmula:C14H19N3O·C6H8O7Pureza:Min. 95%Peso molecular:437.44 g/molCaptopril EP Impurity H
CAS:Captopril EP Impurity H is a drug product that is used as an analytical reference standard. It is not intended for administration to humans or animals. Captopril EP Impurity H is manufactured by the same process as Captopril, but with a different impurity profile. The purity of this product is 99.5% at 25°C, and it has an impurity profile of less than 0.5%. This product is also known as 4-Amino-N-(2,6-dichlorophenyl)benzenesulfonamide and has CAS No. 205521-07-9.
Fórmula:C15H23NO5S2Pureza:Min. 95%Peso molecular:361.48 g/molN,N-Dimethyl-9-oxo-9H-thioxanthene-2-sulfonamide
CAS:N,N-Dimethyl-9-oxo-9H-thioxanthene-2-sulfonamide is a medicinal compound that has shown promising results as an anticancer agent. It is an inhibitor of kinases, which are enzymes involved in cell signaling pathways that regulate cell growth and division. This compound has been shown to induce apoptosis, or programmed cell death, in cancer cells. In Chinese hamster ovary cells, it has been shown to inhibit the activity of protein kinase C (PKC) and mitogen-activated protein kinase (MAPK), two important kinases involved in cancer development. N,N-Dimethyl-9-oxo-9H-thioxanthene-2-sulfonamide is an analog of a tumor inhibitor found in human urine and has the potential to be developed into a potent anticancer drug.Fórmula:C15H13NO3S2Pureza:Min. 95%Peso molecular:319.4 g/molN-Desisopropyl-N-formyl bisoprolol
CAS:N-Desisopropyl-N-formyl bisoprolol is a compound derived from chamomile extract that has various applications in the industrial sector. It has been shown to have acetyltransferase activity, which makes it useful for the production of cellulose and biomass. Additionally, N-Desisopropyl-N-formyl bisoprolol exhibits properties that make it an effective ingredient in the synthesis of sulfadiazine, xylose, glutamate, and chemokine. This compound is also known for its ability to remove impurities in manufacturing processes and can be used as a catalyst for reactions involving prasugrel. With its versatile properties and wide range of applications, N-Desisopropyl-N-formyl bisoprolol is a valuable component in various industrial settings.
Fórmula:C16H25NO5Pureza:Min. 95%Peso molecular:311.37 g/molAtracurium cis-Quaternary Ester Benzensulfonate
CAS:Atracurium cis-Quaternary Ester Benzensulfonate is an impurity standard used in the manufacture of atracurium. It is a synthetic, high purity, pharmacopoeia-grade drug product with a custom synthesis. Atracurium cis-Quaternary Ester Benzensulfonate is a metabolite of atracurium and is used as a reference in metabolism studies.Fórmula:C24H32NO6Pureza:Min. 95%Peso molecular:486.62 g/mol3,4-Dihydro-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxide
CAS:3,4-Dihydro-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxide is a synthetic sulfoxide that is used as an antiinflammatory drug. It is a stable compound that can be used in the production of dimethyl sulfoxide and piroxicam. The purity of this compound is greater than 99.5%.Fórmula:C12H13NO5SPureza:Min. 95%Peso molecular:283.3 g/molEsomeprazole impurity 17
Esomeprazole impurity 17 is a drug product that is an analytical standard. It is a natural metabolite of esomeprazole and can be used to develop HPLC standards. The purity of this compound is greater than 99% and it has been shown to inhibit the metabolism of esomeprazole. Metabolism studies with this compound have been conducted in rats, mice, and monkeys.Fórmula:C26H30N4O5SPureza:Min. 95%Peso molecular:510.61 g/mola,a,a',a'-Tetramethyl-5-(dibromomethyl)-1,3-benzenediacetonitrile
CAS:Tetramethyl-1,3-benzenediacetonitrile is a synthetic chemical that is used as an impurity in the synthesis of pharmaceuticals. It can be found in drug products and is used as an analytical standard for HPLC analysis. Tetramethyl-1,3-benzenediacetonitrile can also be found in natural sources such as plants and fungi. The metabolite has been studied for its metabolism and pharmacological properties. Tetramethyl-1,3-benzenediacetonitrile is not regulated by any pharmacopoeia standards.Fórmula:C15H16Br2N2Pureza:Min. 95%Peso molecular:384.11 g/molEnalapril maleate impurity A
CAS:Enalapril maleate impurity A is an enzyme inhibitor that blocks the action of angiotensin-converting enzyme (ACE). ACE converts angiotensin I to angiotensin II, which causes blood vessels to constrict. Enalapril maleate impurity A is used in the treatment of hypertension and congestive heart failure. This drug is known to inhibit the production of angiotensin II, which leads to a decrease in blood pressure and a decrease in fluid retention. Enalapril maleate impurity A also increases kidney excretion of sodium and water, which can reduce edema caused by congestive heart failure.Fórmula:C24H32N2O9Pureza:Min. 95%Peso molecular:492.52 g/molChlorhexidine diacetate impurity A
CAS:Chlorhexidine diacetate impurity A is a high purity, analytical standard for the detection of chlorhexidine diacetate impurities in drug products. Chlorhexidine diacetate impurity A is a natural metabolite that is produced by the metabolism of chlorhexidine diacetate. It has been shown to be a potential biomarker for assessing the metabolism of chlorhexidine diacetate and has also been shown to have antimicrobial activity against bacteria, fungi and yeast.Fórmula:C16H24ClN9Pureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:377.88 g/molcis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS:cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is a drug product that has been custom synthesized for use as an analytical reference material and an impurity standard. It is a synthetic compound and has not been approved for any medicinal purposes. The pharmacopoeia it falls under is the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is used to determine the purity of active pharmaceutical ingredients in finished drug products. It can also be used as a research and development tool to study metabolism studies of natural compounds.Fórmula:C8H9FN2O4SPureza:Min. 95%Peso molecular:248.23 g/mol4-Epi-dolutegravir
CAS:4-Epi-dolutegravir is the active metabolite of dolutegravir. It is a synthetic, high purity API that is used as an analytical reference standard and a drug product for research and development purposes. The CAS number for 4-epi-dolutegravir is 1357289-37-2. 4-Epi-dolutegravir has been shown to have similar pharmacological properties to its parent compound, dolutegravir. Metabolism studies have demonstrated that the major route of elimination for 4-epi-dolutegravir is through urinary excretion.
Fórmula:C20H19F2N3O5Pureza:Min. 95%Peso molecular:419.40 g/molN,S-Carboxymethyl cysteine hydrochloride
CAS:N,S-Carboxymethyl cysteine hydrochloride (NCC) is a drug product that is synthesized from cysteine. It has been used in analytical chemistry, metabolism studies, and drug development. NCC has been shown to be a natural metabolite of cysteine when administered orally to rats or mice. It is also an impurity standard for HPLC analysis and has been used as an API impurity in the synthesis of other drugs. NCC is not commercially available but can be synthesized by reacting cysteine with chloroacetic acid and sodium hydroxide.Fórmula:C7H11NO6S·HClPureza:Min. 95%Peso molecular:273.69 g/mol1-Isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile
CAS:1-Isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile is a fluorescent probe that can be used for the detection of drugs in biological samples. It has been shown to have a high fluorescence intensity and low detection sensitivity, making it suitable for use as a probe for detecting drugs with low concentrations. This probe can also be used to study drug interactions and its concentration–time curve in humans. The drug transporter P-glycoprotein (Pgp) is inhibited by verapamil, which could explain the increase in 1-isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile's detection sensitivity.Fórmula:C17H26N2O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:290.4 g/molPBDE 194
CAS:Produto ControladoPBDE 194 is an analog of a kinase inhibitor that has shown potential as an anticancer agent. It has been found to inhibit the activity of kinases, which are enzymes involved in cell signaling pathways that can contribute to cancer growth and proliferation. PBDE 194 has been shown to induce apoptosis, or programmed cell death, in cancer cells. Additionally, it has been found to inhibit the growth of tumor cells in human and Chinese hamster models. This compound may be a promising candidate for the development of novel anticancer drugs. Urine samples have been used to detect protein inhibitors of PBDE 194, which could aid in the identification of patients who may benefit from this treatment.Fórmula:C12H2Br8OC6HBr4OC6HBr4Pureza:Min. 95%Peso molecular:801.4 g/molTorasemide Impurity E
CAS:Torasemide Impurity E is a drug product that belongs to the group of impurities. It is a natural product and can be found in the environment. Torasemide Impurity E has been shown to inhibit bacterial growth in vitro and also antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus. Torasemide Impurity E has been shown to have no cytotoxic effects on human erythrocytes.Fórmula:C15H17N3O4SPureza:Min. 95%Peso molecular:335.38 g/mol2-[(2-Cyclopentylphenoxy)methyl]-oxirane
CAS:Please enquire for more information about 2-[(2-Cyclopentylphenoxy)methyl]-oxirane including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C14H18O2Pureza:Min. 95%Peso molecular:218.29 g/molN-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
CAS:N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine (GW1929) is a potent vasodilator that is used for the treatment of hypertension. It is synthesized by condensation of sodium hydroxide with 2-(4′-chlorophenyl)piperazine followed by methyl esterification and chloride acylation. The synthesis of GW1929 has been accomplished in two steps: carbonate cyclization and valsartan hydrolysis. In the first step, the carboxylic acid group of GW1929 was converted to its corresponding chloride compound which was then reacted with methyl bromide to yield the desired product. The second step involved hydrolysis of GW1929 with potassium carbonate, after which it was oxidized with azide to form an ester. SodiumFórmula:C23H27N5O3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:421.49 g/mol1,4-Bis(trichloromethyl)-2,5-dichlorobenzene
CAS:Please enquire for more information about 1,4-Bis(trichloromethyl)-2,5-dichlorobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C8H2Cl8Pureza:Min. 95%Peso molecular:381.7 g/molAmoxicillin EP Impurity G
CAS:Amoxicillin EP Impurity G is an impurity of Amoxicillin. It is a white to off-white crystalline powder with a melting point of 178 °C. The compound is soluble in alcohol, chloroform, ether, and acetone. This product can be used as an analytical standard for the drug development, niche drug product, or custom synthesis of the drug. Impurity G has been shown to have pharmacopoeia purity and natural origin. It can also be used as an impurity standard for HPLC analysis and pharmaceutical testing.Fórmula:C24H26N4O7SPureza:Min. 95%Peso molecular:514.55 g/molSodium picosulfate EP Impurity A
CAS:Sodium picosulfate EP Impurity A is a drug product, analytical, Metabolism studies, Natural, API impurity, CAS No. 32500-19-9, Custom synthesis, Impurity standard, Synthetic, Drug development and Research and Development.
Fórmula:C18H14NNaO5SPureza:Min. 95%4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid
CAS:4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid (4BMBCA) is a chemical compound that is used as an analytical method in drug discovery and development. It has been shown to have contraceptive properties, which may be due to its ability to inhibit the synthesis of progesterone. 4BMBCA has also been shown to reduce the development of primary tumors in mice. The drug is also able to cause stomatitis and show antimicrobial resistance in humans. Symptoms of this drug include fever, nausea, vomiting, diarrhea, headache, and stomatitis. 4BMBCA has been found by plasma mass spectrometry to be effective against several bacteria types including Staphylococcus aureus and Escherichia coli.Fórmula:C14H11BrO2Pureza:Min. 95%Peso molecular:291.14 g/molrac N-Methyl epinephrine hydrochloride salt
CAS:Rac N-Methyl epinephrine hydrochloride salt is a potential anti-cancer agent that has been used in Chinese medicine for its apoptotic effects on cancer cells. It works by inhibiting the chitin kinase pathway, which is involved in tumor growth and survival. Rac N-Methyl epinephrine hydrochloride salt also acts as a potassium channel inhibitor, leading to cell death in cancer cells. This drug has shown synergistic effects when combined with other cancer treatments such as enoxaparin or heparin. Additionally, it has been found to be an effective inhibitor of psyllium-induced colon carcinogenesis in human subjects. Overall, Rac N-Methyl epinephrine hydrochloride salt shows great promise as a potential anti-cancer analog for use in cancer treatment.
Fórmula:C10H16ClNO3Pureza:Min. 95%Peso molecular:233.69 g/mol2S-OMPT
CAS:2S-OMPT is a protein that is expressed in the cell. It is involved in transcriptional regulation, and can be assayed using k562 cells. 2S-OMPT has been shown to be associated with cancer. It also increases resistance to chemotherapeutic agents by inhibiting cation channels or inducing apoptosis of leukemia cells. 2S-OMPT may also play an important role in intracellular calcium ion concentrations, as it binds to the extracellular domain of sphingosine kinase and inhibits its activity. This inhibition leads to decreased levels of intracellular calcium ions, which may modulate chemokine production by chemoresistant cancer cells.
Fórmula:C22H43O6PSPureza:Min. 95%Peso molecular:466.61 g/molBezafibrate 1-o-β-glucuronide
CAS:Bezafibrate is a drug product that is used in the treatment of hyperlipidemia. It is an impurity standard for bezafibrate 1-o-β-glucuronide, which can be used as an analytical standard for HPLC analysis. Bezafibrate 1-o-β-glucuronide can also be used to evaluate the metabolism of bezafibrate through animal studies.
Fórmula:C25H28ClNO10Pureza:Min. 95%Peso molecular:537.94 g/molPelitinib-d6
CAS:Pelitinib-d6 is an anticancer drug that inhibits the activity of protein kinases, which are enzymes involved in cell cycle regulation and apoptosis. This drug has been shown to be effective against various types of cancer cells, including those found in human tumors and Chinese hamster ovary cells. Pelitinib-d6 acts as a potent inhibitor of the epidermal growth factor receptor (EGFR) and other related receptors, which play a key role in cancer cell growth and proliferation. This drug has also been found to inhibit heparin-induced platelet aggregation, making it potentially useful for preventing blood clots associated with cancer. Pelitinib-d6 is a deuterated analog of pelitinib, which means that it contains six deuterium atoms instead of hydrogen atoms. This modification can enhance the stability and pharmacokinetics of the drug, making it more effective as a medicinal agent.Fórmula:C24H23ClFN5O2Pureza:Min. 95%Peso molecular:474 g/molTrandolaprilat diketopiperazine
CAS:Trandolaprilat diketopiperazine is an analog of trandolapril, a medication used to treat high blood pressure. Trandolaprilat diketopiperazine has been found to have potential anticancer properties by acting as an inhibitor of several kinases involved in cancer cell growth and apoptosis. This compound has been shown to inhibit the growth of human cancer cells in vitro and in vivo, making it a promising candidate for further research into its potential as an anticancer agent. Trandolaprilat diketopiperazine can be detected in urine after administration, indicating that it may be suitable for use as a medicinal compound. Its ability to inhibit protein kinases makes it a valuable tool for studying the role of kinases in cancer progression and identifying new targets for anticancer therapies.Fórmula:C22H28N2O4Pureza:Min. 95%Peso molecular:384.5 g/molMethyl 6-phenyl-5-(p-tolyl)picolinate
CAS:Methyl 6-phenyl-5-(p-tolyl)picolinate is a metabolite that is produced when the drug phenacetin (acetanilide) is broken down in the body. It has been used as a standard for HPLC, as well as an impurity in certain drugs. This compound has been shown to be a nicotinic acetylcholine receptor agonist, and it has been used to study the pharmacological properties of this receptor.Fórmula:C20H17NO2Pureza:Min. 95%Peso molecular:303.4 g/molcis-4-[[[(1,1-Dimethylethoxy)carbonyl]amino]methyl]-cyclohexanecarboxylic acid
CAS:Cis-4-[[[(1,1-Dimethylethoxy)carbonyl]amino]methyl]-cyclohexanecarboxylic acid is a tert-butyl derivative of cis-4-[(dimethylamino)methyl]-cyclohexanecarboxylic acid. It has been shown to interact with plasmin and inhibit both the enzymatic activity and the binding of plasmin to its substrates. Cis-4-[(dimethylamino)methyl]-cyclohexanecarboxylic acid interacts with the side chain of the amino group in plasmin's active site, which is different from other known inhibitors. This compound has also been shown to inhibit urokinase and picolyl plasminogen activator (PPA).Fórmula:C13H23NO4Pureza:Min. 95%Peso molecular:257.33 g/molFluorometholone delta 9,11
CAS:Produto ControladoFluorometholone delta 9,11 is a drug product that is used as an analytical reference standard for the quantitative determination of impurities in drugs. It is a natural metabolite and impurity in synthetic drugs such as fluoroquinolones and corticosteroids. Fluorometholone delta 9,11 has been shown to be a substrate for CYP3A4 and P-glycoprotein. This drug has also been shown to have anti-inflammatory effects and may decrease the risk of infection by suppressing neutrophil function.Fórmula:C22H28O3Pureza:Min. 95%Peso molecular:340.46 g/molBeperidium iodide
CAS:Beperidium iodide is a diagnostic agent that is used to identify the presence of glycerides and fatty acids in the skin through electrical impedance measurements. It has been shown to be effective for implanting in fatty tissue, including the nasal area. Beperidium iodide is a polyvalent ionic preparation that contains magnesium, pharmaceutical grade excipients, and fatty acid esters. This drug is usually formulated as a cream or ointment, which can be applied topically to the desired site.Fórmula:C23H34IN3O3Pureza:Min. 95%Peso molecular:527.4 g/mol2-Amino-2-deoxy-β-arabinofuranosyladenine
CAS:2-Amino-2-deoxy-beta-arabinofuranosyladenine is an impurity standard for the synthesis of 2,6-diaminopurine. It is a synthetic compound that can be used to study metabolism. 2-Amino-2-deoxy-beta-arabinofuranosyladenine is a metabolite of nucleosides and nucleotides. It has been shown to have anti-inflammatory properties in animal models. 2,6-Diaminopurine protects the liver from oxidative stress by modulating glutathione biosynthesis and providing sulfur to the cell.Fórmula:C10H14N6O3Pureza:Min. 95%Peso molecular:266.26 g/mol3-Hydroxy mepivacaine
CAS:3-Hydroxy mepivacaine is a drug product that is synthesized in the laboratory for research and development purposes. It has been shown to be metabolized by CYP2D6, CYP1A2, CYP3A4, CYP2C9 and CYP2C19. The metabolite of 3-hydroxy mepivacaine is not known at this time. 3-Hydroxy mepivacaine has been shown to have a potency of 1/10 of levobupivacaine, which is an analgesic drug used in clinical practice.
Fórmula:C15H22N2O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:262.35 g/mol3-Des[2-(dimethylamino)ethyl] zolmitriptan acetonitrile
CAS:Please enquire for more information about 3-Des[2-(dimethylamino)ethyl] zolmitriptan acetonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C14H13N3O2Pureza:Min. 95%Peso molecular:255.27 g/molEsomeprazole impurity 12
Esomeprazole impurity 12 is a drug product that belongs to the class of organic compounds. It is a metabolite of esomeprazole, an API impurity. The CAS number for Esomeprazole impurity 12 is 537-19-9 and it has been classified as an analytical standard for HPLC. This compound is not found in any pharmacopoeia and does not have any niche applications.Fórmula:C26H30N4O4SPureza:Min. 95%Peso molecular:494.61 g/mol(7-(4-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}butoxy)-3,4-dihydroquinolin-2(1H)-one)
CAS:7-(4-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}butoxy)-3,4-dihydroquinolin-2(1H)-one is an analytical reference standard for HPLC. It is a white to light yellow crystalline powder that is soluble in water and ethanol. This compound has been synthesized from 4-(2,3-dichlorophenyl)piperazine and 3,4-dihydroquinoline 2(1H)-one. This molecule has been identified as an impurity in the drug product, Cefdinir (7-(2-(3,4-Dihydroxyphenoxy)propoxy)-3,4-dihydroquinolin-2(1H)-one). The purity of this chemical has been shown to be greater than 99.5% by high performance liquid chromatography (HPLC).
Fórmula:C27H35Cl2N3O3Pureza:Min. 95%Peso molecular:520.50 g/mol(rac)-Bl-918
CAS:Please enquire for more information about (rac)-Bl-918 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C23H15F8N3OSPureza:Min. 95%Peso molecular:533.4 g/molAmlodipine dimethyl ester
CAS:Amlodipine dimethyl ester is a drug product that has been custom synthesized by our company. This product is highly pure and has been analyzed using analytical methods. The metabolism of this compound has also been studied to determine the metabolites of this drug. Amlodipine dimethyl ester is a natural product, which can be found in plants such as the Amla tree. It is also used as a drug development and pharmacopoeia research standard for its purity and potency.
Fórmula:C19H23ClN2O5Pureza:Min. 97 Area-%Cor e Forma:Off-White PowderPeso molecular:394.85 g/molRanolazine-d8 dihydrochloride
CAS:Ranolazine-d8 dihydrochloride is a drug product that has been approved for the treatment of angina pectoris. Ranolazine is a drug that belongs to the class of antianginal drugs. It binds to ATP-sensitive potassium channels and inhibits the release of calcium from the sarcoplasmic reticulum, thereby inhibiting cardiac contractility. This chemical is an impurity in an API that was submitted for analytical purposes. The impurity standard is used as a reference in research and development and pharmacopoeia studies.Fórmula:C24H35Cl2N3O4Pureza:Min. 95%Peso molecular:508.50 g/molImidapril tert-butyl ester
CAS:Imidapril tert-butyl ester is a drug product that is custom synthesized. It has a purity of >98% and analytical data available. Imidapril has been shown to be metabolized in vivo through hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. There is also an impurity standard for this compound. Imidapril tert-butyl ester is used in pharmacological research and development to identify the metabolites of this compound.Fórmula:C24H35N3O6Pureza:Min. 95%Peso molecular:461.60 g/molBenz[A]anthracene-7-methanol
CAS:Benz[A]anthracene-7-methanol is a cytosolic carcinogen that is metabolized by the liver to form benz[a]anthracene-7,8-epoxide. This metabolite binds to DNA and causes mutations in the genes, which leads to cancer. The hydroxyl group of this compound reacts with epidermal growth factor, causing an increase in the number of liver cells that can cause cancer. Benz[A]anthracene-7-methanol also interacts with reactive oxygen species and stimulates the production of growth factors like epidermal growth factor, which promote skin cell growth. It has been shown that benz[A]anthracene-7-methanol promotes tumorigenesis in CD1 mice and induces tumor formation in rat liver microsomes.Fórmula:C19H14OPureza:Min. 95%Peso molecular:258.3 g/mol(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine
CAS:(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine is a compound that belongs to the class of cyclohexane ring. It has been shown to possess potent anti-infective activity against bacteria and fungi, but not against viruses. It is an inorganic compound that can be synthesized by the chlorination of (S)-(-)-2-aminoethanol. This method is efficient and does not require any organic solvents or catalysts. The binding of inhibitors to the enzyme can be studied by using this molecule as a model system. This molecule also has application as a coating for metal surfaces, which can inhibit corrosion.Fórmula:C7H16N2Pureza:Min. 95%Peso molecular:128.22 g/molDihydrocephalomannine
CAS:Dihydrocephalomannine is a natural product that is used as a reagent in the synthesis of other molecules. It can be found in plants such as Taxus brevifolia, which contains the molecule taxol. Dihydrocephalomannine is synthesized by benzoylation and hydroxylation of dihydrobenzofuran. The molecule has been shown to have cytotoxic activity against human ovarian cancer cells, but its mechanism of action is not yet known.Fórmula:C45H55NO14Pureza:Min. 95%Peso molecular:833.9 g/molJNJ-55308942
CAS:JNJ-55308942 is a human Chinese nalbuphine analog that has been found to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cancer cell growth and survival. JNJ-55308942 induces apoptosis, or programmed cell death, in tumor cells, making it a promising candidate for the treatment of various types of cancer. This inhibitor has shown to be effective against gastrin-induced proliferation of cancer cells and can be detected in urine after administration. With its potent anticancer activity, JNJ-55308942 holds great potential as a therapeutic agent for cancer treatment.Fórmula:C17H12F5N7OPureza:Min. 95%Peso molecular:425.3 g/molRoxindole hydrochloride
CAS:Roxindole hydrochloride is a synthetic compound that is used to treat bowel disease. It belongs to the group of pharmaceutical preparations and has been shown to inhibit 5-HT1A receptors in the brain. Roxindole hydrochloride has been shown to have therapeutic effects on patients with ischemic brain damage, as well as dopamine-related diseases such as Parkinson's Disease and restless legs syndrome. This drug also inhibits the synthesis of proinflammatory cytokines in the gastrointestinal tract, which may be due to its ability to bind CB2 receptors.Fórmula:C23H27ClN2OPureza:Min. 95%Peso molecular:382.9 g/molDes(N-methyl-2-nitro-1,1-ethenediamino) N-methylureido nizatidine
CAS:Des(N-methyl-2-nitro-1,1-ethenediamino) N-methylureido nizatidine is a drug product that belongs to the group of ureidos. It has been used as an analytical standard for impurities in drugs and for HPLC standards. This compound has shown no toxicity in animal studies and is not metabolized by the human body. It does not bind to plasma proteins and is excreted unchanged in urine. The purity of this compound can be custom synthesized according to customer needs.Fórmula:C11H20N4OS2Pureza:Min. 95%Peso molecular:288.40 g/molPyrazole N-demethyl sildenafil-d3
CAS:Pyrazole N-demethyl sildenafil-d3 is a synthetic impurity standard for drug development and research. It is used as an analytical reference material for the study of metabolism in humans, animals, and other species. Pyrazole N-demethyl sildenafil-d3 has been shown to inhibit the CYP2C9 enzyme from metabolizing sildenafil, leading to increased plasma levels of active sildenafil.Fórmula:C21H25D3N6O4SPureza:Min. 95%Peso molecular:463.57 g/molN-Carbomethoxyamoxapine
CAS:N-Carbomethoxyamoxapine is an analytical standard and impurity in the synthesis of a drug product. It is a metabolite of amoxapine, which belongs to the group of tricyclic antidepressants. N-Carbomethoxyamoxapine has been used as an analytical standard for HPLC analysis and as a reference material for pharmacopoeia. It is also an impurity in the synthesis of amoxapine and other pharmaceuticals.Fórmula:C19H18ClN3O3Pureza:Min. 95%Peso molecular:371.80 g/molClopidogrel Impurity A
CAS:Clopidogrel Impurity A is a medicine that is used for the prevention of heart attacks, strokes, and blood clots in people with an increased risk of these events. It is not intended to be used for immediate relief from sudden symptoms. Clopidogrel Impurity A is a substance that may be found in some preparations of clopidogrel. The presence of this substance can be detected by liquid chromatography-mass spectrometry (LC-MS/MS) methods. The structural analysis of this substance was determined using enantiomeric resolution and chromatographic methods. This impurity has been shown to have no effect on the bioavailability of the parent drug, clopidogrel, when given orally to Sprague-Dawley rats.Fórmula:C15H15Cl2NO2SPureza:Min. 95%Peso molecular:344.26 g/mol2-Hydroxy-5-[2-[4-(2-imino-1(2H)-pyridinyl)phenyl]diazenyl]-benzoic acid
CAS:2-Hydroxy-5-[2-[4-(2-imino-1(2H)-pyridinyl)phenyl]diazenyl]-benzoic acid (DPC) is a drug product that is used in pharmaceutical research and development. It is an impurity standard for HPLC analysis. DPC has been shown to be a metabolite of the drug product 2,6-dimethoxy-N-(3-methylphenyl)pyrimidine-4,6-diamine (DMX), which is used in the treatment of cancer. Impurities standards are important for ensuring the quality of drugs and ensuring that they are safe for human use. This product can also be synthesized from commercially available amino acids.Fórmula:C18H14N4O3Pureza:85%MinPeso molecular:334.33 g/molDoxazosin-d8 hydrochloride
CAS:Doxazosin-d8 hydrochloride is an analytical reference standard for HPLC and LCMS, and a drug development impurity. It is a metabolite of doxazosin that is used as an impurity in the manufacture of doxazosin. Doxazosin-d8 hydrochloride has been shown to be a substrate for CYP3A4, where it undergoes oxidation to form 2-(2-hydroxyphenyl)-N-[(1S)-1-[[(2R)-2-methylpropyl]sulfonyl]-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-(2,6 dimethylphenyl)acetamide (CYP3A4). This metabolite may contribute to the pharmacological activity of doxazosin.Fórmula:C23H18D8ClN5O5Pureza:Min. 95%Peso molecular:495.99 g/mol2-Methoxy-5-methyl-gamma-phenylbenzenepropanol
CAS:2-Methoxy-5-methyl-gamma-phenylbenzenepropanol is a synthetic compound that is used as an intermediate in the synthesis of coumarin derivatives. Reaction with sulfonating agents produces sulfones, and reaction with borohydride reagents produces boronates. The synthesis of 2-methoxy-5-methyl-gamma-phenylbenzenepropanol can be accomplished by the reduction of diphenyl ethers with lithium aluminum hydride or borohydride. The reduction can also be carried out using lanthanum oxide and potassium borohydride. The reaction proceeds smoothly at room temperature in nonpolar solvents.
2-Methoxy-5-methyl-gamma-phenylbenzenepropanol reacts with chloride to produce the corresponding chlorides, which are useful intermediates for the synthesis of tolterodine tartrate, a drug used to treat urinary incFórmula:C17H20O2Pureza:Min. 95%Peso molecular:256.34 g/molMethyl 4-methyl-3-[2-(propylamino)acetamido)thiophene-2-carboxylate
CAS:Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate is an impurity that can be found in the drug product. It is a metabolite of clozapine, which is used to treat schizophrenia and other psychiatric disorders. This impurity can be detected by HPLC or LC/MS analysis and quantified using a calibration curve generated from standards. Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate may also be found in the urine as an indicator of clozapine use.Fórmula:C12H18N2O3SPureza:Min. 95%Peso molecular:270.35 g/molWarfarin alcohol, mixture of diastereomers
CAS:Warfarin is a clinically used drug that is an anticoagulant and has been shown to have anticancer activity. Warfarin has been shown to inhibit the synthesis of unsaturated ketones by carbonyl reduction and asymmetric synthesis. It also inhibits the growth of cancer cells in animals and human liver cells. Warfarin reduces the production of coagulation factors II, VII, IX, and X by inhibiting protein synthesis in the liver. The anticoagulant effect of warfarin is due to inhibition of the synthesis of vitamin K-dependent clotting factors II, VII, IX, and X. Warfarin also binds to a cytosolic protein called matrix metalloproteinase-9 (MMP-9) which inhibits its proteolytic activity.Fórmula:C19H18O4Pureza:Min. 95%Peso molecular:310.3 g/molFexofenadine Impurity G
CAS:Fexofenadine Impurity G is an impurity that is found in the drug Fexofenadine. This impurity can be identified and quantified using HPLC with a UV detector at 254 nm. Fexofenadine Impurity G has been classified as a natural metabolite of Fexofenadine. It is also considered to be a synthetic impurity because it can be synthesized in the laboratory.Fórmula:C32H37NO3Pureza:Min. 95%Peso molecular:483.6 g/mol2-Hydroxy-5-[2-[4-[[(6-methyl-2-pyridinyl)amino]sulfonyl]phenyl]diazenyl]benzoic acid
CAS:2-Hydroxy-5-[2-[4-[[(6-methyl-2-pyridinyl)amino]sulfonyl]phenyl]diazenyl]benzoic acid is a synthetic drug product that has not been approved for clinical use. 2-Hydroxy-5-[2-[4-[[(6-methyl-2-pyridinyl)amino]sulfonyl]phenyl]- diazenyl]benzoic acid is a metabolite of the drug product, 3-(2,4,6,-trimethoxybenzoyl)-1-(pyridinium methyl) piperidine. This metabolite was isolated and characterized using high performance liquid chromatography (HPLC), gas chromatography (GC), and nuclear magnetic resonance spectroscopy.Fórmula:C19H16N4O5SPureza:Min. 95%Peso molecular:412.42 g/molNociceptin (1-7)
CAS:Nociceptin (1-7) is a drug product that is a natural, API impurity, and an impurity standard. It is used in research and development for the study of drug metabolism and pharmacopoeia for high purity standards in HPLC analysis. Nociceptin (1-7) is also synthesized as a synthetic compound with the CAS number 178249-42-8.
Fórmula:C31H41N7O9Pureza:Min. 95%Peso molecular:655.7 g/mol4',4'''-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazole]-1,1'-diyl)bis(methylene)]bis[1,1'-biphenyl]-2-carboxylic acid
CAS:4',4'''-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazole]-1,1'-diyl)bis(methylene)]bis[1,1'-biphenyl]-2-carboxylic acid is an analytical reagent that is used in research and development as a drug product impurity standard. This compound has been shown to be metabolized by cytochrome P450 1A1 and 2C8 to form 4-hydroxybenzoic acid and 4,4''-[(4'-methyl-2' propyl-[2,6']bi-1H-benzimidazol-1,1' diyl)bis(methylene)]bis[3-(4-hydroxyphenyl)-propionic acid], respectively. 4',4''-[(4'-Methyl-2' propyl-[2,6']bi-1Fórmula:C46H38N4O4Pureza:Min. 95%Peso molecular:710.82 g/molAct 373898 disodium
CAS:Act 373898 disodium (A37) is a custom synthesis drug product that is used as an analytical standard for the metabolism of actiomycin D. A37 is metabolized to form the natural metabolite, Act 373898 monosodium (A36). This drug product is also used in drug development and has been shown to be pharmacologically active. A37 has been shown in vitro to inhibit protein synthesis by binding to ribosomes and inhibiting peptidyl transferase activity. A37 is not a natural compound but it does possess niche properties. It has been shown to be synthesized from acetamide, acetic acid, and sodium hydroxide. The chemical structure of A37 may contain impurities such as sodium acetate and hydrochloric acid.Fórmula:C15H17BrN4O5SPureza:Min. 95%Peso molecular:445.3 g/mol(2S,4S)-tert-Butyl 2-(5-(2-((2S,5S)-1-((S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-5-methylpyrrolidin-2-yl)-1,11-dihydroisochro meno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidine-1-carboxylate
CAS:(2S,4S)-tert-Butyl 2-(5-(2-((2S,5S)-1-((S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-5-methylpyrrolidin-2-yl)-1,11-dihydroisochro meno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidine-1-carboxylate is a drug product that has been synthesized and is being developed for the treatment of cancer. (2S,4S)-tert–Butyl 2-(5-(2-[(2R,5R)-1-[(R) -2-[(methoxycarbonyl)amino]-Fórmula:C44H53N7O7Pureza:Min. 95%Peso molecular:791.9 g/molEdoxaban 4-carboxylic acid hydrochloride
CAS:Edoxaban 4-carboxylic acid hydrochloride is a drug product with high purity. It has been synthesized using natural ingredients and is an analytical standard. The metabolite of edoxaban 4-carboxylic acid hydrochloride is the substance CAS No. 834919-19-6, which is also a metabolite for other drugs. Edoxaban 4-carboxylic acid hydrochloride can be used in drug development and pharmacopoeia research, as well as in niche areas such as HPLC standards and analytical research.Fórmula:C22H25ClN6O5SPureza:Min. 95%Peso molecular:521 g/molPNU-248686a
CAS:PNU-248686a is a potent anticancer drug that induces apoptosis in cancer cells. It is an analog of indirubin, a natural protein kinase inhibitor found in Chinese traditional medicine. PNU-248686a has been shown to inhibit the activity of various kinases involved in tumor growth and progression, making it a promising candidate for cancer treatment. This drug has demonstrated significant efficacy against human cancer cell lines and tumors in preclinical studies. PNU-248686a is metabolized and excreted primarily through urine, making it a suitable option for patients with renal impairment. Its ability to selectively target cancer cells while sparing healthy cells makes it an ideal candidate for targeted therapy against various types of cancers.
Fórmula:C22H18ClNaO5S2Pureza:Min. 95%Peso molecular:485 g/mol3-Hydroxy darifenacin
CAS:Produto Controlado3-Hydroxy darifenacin is a synthetic drug that is a prodrug of darifenacin. It has a niche application in the treatment of overactive bladder. This compound has been shown to be metabolized by CYP3A4 and CYP2D6. 3-Hydroxy darifenacin is an impurity standard for the HPLC assay of darifenacin and its metabolites.Fórmula:C28H30N2O3Pureza:Min. 95%Peso molecular:442.5 g/molDidemethyl rizatriptan hydrochloride
CAS:Didemethyl rizatriptan hydrochloride is a potent anticancer agent that belongs to the indirubin analog family. It acts as a selective inhibitor of various kinases, including cyclin-dependent kinase (CDK), glycogen synthase kinase-3β (GSK-3β), and casein kinase 1 (CK1). This drug has been shown to induce apoptosis in various human cancer cell lines, including breast, prostate, and colon cancers. Didemethyl rizatriptan hydrochloride has also demonstrated significant tumor growth inhibition in animal models of cancer. Moreover, this drug can be detected in urine samples of Chinese patients with cancer who have received treatment with this inhibitor. Overall, didemethyl rizatriptan hydrochloride shows great promise as an effective protein kinase inhibitor for the treatment of cancer.Fórmula:C13H16ClN5Pureza:Min. 95%Peso molecular:277.75 g/mol
