APIs para pesquisa e impurezas
Os Ingredientes Farmacêuticos Ativos (APIs) são as substâncias nos medicamentos responsáveis por seus efeitos terapêuticos. Nesta seção, você encontrará uma ampla variedade de APIs destinados a uso em pesquisa. Esses compostos são essenciais para o desenvolvimento, teste e validação de novas formulações farmacêuticas. Na CymitQuimica, oferecemos APIs de alta qualidade para apoiar a pesquisa em descoberta e desenvolvimento de medicamentos.
Subcategorias de "APIs para pesquisa e impurezas"
- Aminoácidos e Derivados(12.440 produtos)
- Antraquinonas e Derivados(407 produtos)
- Derivados de Benzimidazol e Imidazol(10.464 produtos)
- Derivados das Benzodiazepinas(335 produtos)
- Carboidratos e Glicoconjugados(5.388 produtos)
- Ésteres e Derivados(42.306 produtos)
- Ácidos Graxos e Derivados Lipídicos(32.486 produtos)
- Flavonoides e Polifenóis(17.100 produtos)
- Radicais Livres e Agentes Oxidantes/Redutores(214 produtos)
- Cetonas e Derivados(2.692 produtos)
- Antibióticos Naturais e Semissintéticos(6.409 produtos)
- Nitrilas e Derivados Ciano(3.070 produtos)
- Nitrosaminas e Derivados(55 produtos)
- Nucleosídeos e Nucleotídeos(3.492 produtos)
- Fosfatos e Fosfonatos Orgânicos(1.203 produtos)
- Sulfonatos e Sulfatos Orgânicos(10.451 produtos)
- Compostos Organometálicos(4.425 produtos)
- Outros(6.340 produtos)
- Peptídeos e Proteínas(3.164 produtos)
- Polímeros e Derivados(100 produtos)
- Derivados de Purinas e Pirimidinas(8.974 produtos)
- Derivados de Quinazolina e Quinolina(66.217 produtos)
- Quinonas e Derivados(24.378 produtos)
- Sais e Derivados de API(92.894 produtos)
- Esteroides e Derivados(4.987 produtos)
- Sulfonamidas e Derivados(2.607 produtos)
- Terpenoides e Derivados(3.860 produtos)
- Tiazolidinedionas e Tiopiranos(2.755 produtos)
- Compostos β-Adrenérgicos(231 produtos)
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Foram encontrados 66870 produtos de "APIs para pesquisa e impurezas"
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Decitabine impurity 11
CAS:Decitabine is a drug product that is used as an anti-cancer drug. It is a synthetic, natural, and research and development (R&D) metabolite with the CAS No. 909402-26-2. Decitabine has shown anticancer activity in vitro and in vivo against leukemia cells. This compound is an impurity of the API decitabine that is manufactured by a chemical synthesis process. The analytical impurities are 11 compounds that have been identified from the HPLC standard of this API. The metabolites of these compounds are also included in this standard. High purity decitabine should be obtained for pharmacopoeia studies and niche applications such as HPLC standards, pharmaceuticals, or research purposes.Fórmula:C9H13N3O5Pureza:Min. 95%Peso molecular:243.22 g/mol22-Oxo-vincaleukoblastine 6'-oxide
CAS:22-Oxo-vincaleukoblastine 6'-oxide is a synthetic drug with no known clinical use. It is an impurity of the vinca alkaloid drug vinblastine and may be found in small amounts in other vinca alkaloid drugs. 22-Oxo-vincaleukoblastine 6'-oxide is a metabolite of the vinca alkaloids, which are used as anticancer drugs. This substance has been shown to inhibit the metabolism of some cancer cells, leading to increased cell proliferation.
Fórmula:C46H56N4O11Pureza:Min. 95%Cor e Forma:PowderPeso molecular:840.96 g/mol4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine
CAS:4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine is an impurity standard of the drug product. It is a high purity synthetic compound with a niche in pharmacopoeia and drug development. 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine has been shown to be a metabolite of the natural product.Fórmula:C6H5IN4Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:260.04 g/mol2-Amino-5,6-dichloro-3(4H)-quinazolineacetic acid methyl ester monohydrobromide
CAS:2-Amino-5,6-dichloro-3(4H)-quinazolineacetic acid methyl ester monohydrobromide is a metabolite of the drug product 2-amino-5,6-dichloroquinazoline acetic acid methyl ester. It is a synthetic compound that is used as an impurity standard for pharmaceuticals and other products. This chemical can be custom synthesized to meet your needs. It has been shown to have high purity and can be used in research and development or as a pharmacopoeia reference material.Fórmula:C11H12Cl2BrN3O2Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:369.04 g/molRiboflavin EP Impurity C
CAS:Riboflavin EP Impurity C is a synthetic compound that is used as an impurity standard in the manufacture of Riboflavin-5'-Phosphate. Riboflavin EP Impurity C is also a metabolite that can be found in human urine, and is used to study metabolism.Fórmula:C13H18N4O6Pureza:90%MinCor e Forma:PowderPeso molecular:326.31 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide
CAS:5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide is an ammonium salt of a sulfoxide with a chloride. It is also known as esomeprazole magnesium. This drug is used in the preparation of pharmaceutical preparations and is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions. The magnesium salt form is a polymorphic substance that has a crystalline form that occurs in nature, called alpha form, and a synthetic form that occurs in laboratory experiments and has been designated beta form. The alpha form exhibits enantioselectivity when it binds to the enzyme pepsin, which causes the drug to have an antiulcer effect.Fórmula:C17H19N3O4SPureza:Min. 95%Cor e Forma:PowderPeso molecular:361.42 g/mol2H,5H-Pyrano[4,3-b]pyranyl mupirocin sodium impurity
CAS:2H,5H-Pyrano[4,3-b]pyranyl mupirocin sodium impurity is an impurity standard that has been custom synthesized for research and development purposes. It has a CAS number of 116182-44-6, which is the same as the parent compound. 2H,5H-Pyrano[4,3-b]pyranyl mupirocin sodium impurity is a metabolite of Mupirocin Sodium (CAS No. 99765-92-8). This impurity has been used in pharmacopoeia drug development and for analytical studies such as HPLC.Fórmula:C26H43NaO9Pureza:Min. 95%Cor e Forma:PowderPeso molecular:522.6 g/molN-Desmethyl galanthamine
CAS:Produto ControladoN-Desmethyl galanthamine is a plant alkaloid that is found in the Huperzia serrata plant. It has been shown to have cholinergic activity and calcium binding properties. N-Desmethyl galanthamine inhibits acetylcholinesterase, an enzyme responsible for the breakdown of acetylcholine, which is a neurotransmitter. This inhibition leads to increased levels of acetylcholine, which results in increased neuron stimulation and improved memory function. N-Desmethyl galanthamine also binds to β2 nicotinic receptor sites and blocks the binding of nicotine, leading to decreased nicotine dependence.
Fórmula:C16H19NO3Pureza:Min. 95%Peso molecular:273.33 g/molbeta-Epoxyabiraterone acetate
CAS:Beta-Epoxyabiraterone acetate is a synthetic and natural metabolite of abiraterone that is used as an API impurity in the synthesis of abiraterone acetate. The drug product is a niche compound with CAS No. 52464-96-6. The Metabolite is an impurity found in the synthesis of beta-epoxyabiraterone acetate. Drug development research and development, analytical methods, and pharmacopoeia are all involved in the production of this compound.Fórmula:C26H33NO3Pureza:Min. 90 Area-%Cor e Forma:White Off-White PowderPeso molecular:407.55 g/molN-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide
CAS:N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide is a pharmaceutical dosage form that is titrated to achieve the desired therapeutic effect. It is used to treat epilepsy and bipolar disorder. Lamotrigine binds to sodium channels in nerve cells and blocks their opening. This prevents the influx of sodium ions that are necessary for neuronal transmission. Lamotrigine has been shown to have an anticonvulsant effect by reducing the frequency of seizures in patients with epilepsy.Fórmula:C16H9Cl4N5OPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:429.09 g/molGliclazide impurity F
CAS:Gliclazide is a sulfonylurea drug that is used to treat type 2 diabetes. The impurity F, which is an impurity standard, can be synthesized by reacting 1-chloro-2,6-difluoroaniline with sodium methoxide in methanol. It is also an API impurity found in the synthesis of gliclazide and can be custom synthesized for research and development purposes. Gliclazide impurity F has a CAS number of 1076198-18-9 and the molecular formula C8H4ClF3NOS. This product has a purity of >99% and is classified as synthetic. It has been shown to have pharmacopoeia activity and can also be used for niche applications such as drug development.Fórmula:C15H21N3O3SPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:323.41 g/molBis-[[2-aminoethyl]thio]methane
CAS:Bis-[[2-aminoethyl]thio]methane is a custom synthesis, drug product, niche, Metabolite, Drug development, Natural, pharmacopoeia and API impurity. This chemical is CAS No. 22907-27-3 and has the molecular weight of 249.00 g/mol. It can be synthesized in the laboratory using the following methods: HPLC standard, Research and Development and Impurity standard. The chemical is an analytical standard with a purity of 99%. This chemical can be used as analytical reagent or in research and development of drugs.Fórmula:C5H14N2S2Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:166.31 g/mol4-(2-Methoxyethyl)phenol
CAS:4-(2-Methoxyethyl)phenol is a synthetic compound that is an antihypertensive agent. It is used to reduce high blood pressure, which may be due to its ability to block the action of angiotensin II, a potent vasoconstrictive hormone, by binding with its receptor. 4-(2-Methoxyethyl)phenol has been shown to be more potent than metoprolol succinate and less toxic than hydroxylated compounds such as propranolol in pharmacokinetic studies. In addition, 4-(2-Methoxyethyl)phenol has been found to have a low risk of congestive heart failure. The industrial process for this substance involves the reaction of hydrochloric acid with phenol in the presence of a catalyst such as aluminium chloride or zinc chloride.
Fórmula:C9H12O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:152.19 g/mol3-[Methyl(phenylmethyl)amino]-1-phenyl-1-propanone hydrochloride
CAS:Nisoxetine is a norepinephrine (NE) reuptake inhibitor that is used as an antidepressant. It has been shown to be a potent and selective NE reuptake inhibitor with a high affinity towards the NE transporter in rat brain synaptosomes, with potency several times higher than that of tricyclic antidepressants. Nisoxetine's major advantage over other antidepressants is its high efficiency, which makes it suitable for large-scale production. The synthesis of nisoxetine involves two steps: 1) reaction of 3-[methyl(phenylmethyl)amino]-1-phenyl-1-propanone hydrochloride with toluene to form the corresponding methyl ester and 2) hydrogenation of the methyl ester to form nisoxetine. This synthesis is efficient, stable, and chiral due to the use of bimetallic catalysts.Fórmula:C17H19NO•HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:289.8 g/molN-Carbamoyl-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine
CAS:N-Carbamoyl-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine is a sulfoxide that can be used as an analytical reagent for the determination of other substances. It is a colorless to white solid that can be prepared by reacting 1,4,5,6,7,8-hexahydroquinoline with methyl mercaptan and sodium hydroxide in ethanol. The detection limit for this compound is 0.01 mg/L. NCAIG has been used in the development of analytical methods for determining endogenous substances such as cyclic adenosine monophosphate (cAMP). This compound has also been used to determine steady state concentrations of drugs and endogenous substances in plasma or urine.Fórmula:C10H18N6OS·2HClPureza:Min. 95%Cor e Forma:White PowderPeso molecular:343.28 g/molN-Acetylmemantine
CAS:N-Acetylmemantine is a drug that inhibits the activity of acetylcholinesterase in the brain. It has been shown to inhibit cancer cell growth and induce apoptosis, as well as inhibit the reaction of hydrolysis of acetonitrile with hydrochloric acid in an organic solvent. N-Acetylmemantine is synthesized by heating ethylene in the presence of hydrochloric acid. The synthesis yields a white solid that consists mainly of N-acetylmethamphetamine. This drug interacts with cellular membranes, which may be due to its ability to react with cholesterol or phospholipids. The interaction leads to changes in membrane permeability, which can result in apoptosis.Fórmula:C14H23NOPureza:Min. 95%Cor e Forma:White PowderPeso molecular:221.34 g/molOlmesartan dimer ester impurity
CAS:The product is an impurity that is used as a standard in HPLC analysis. It is a natural metabolite of olmesartan, which is a drug marketed for the treatment of hypertension. The purity levels are high and the material has been shown to be stable with respect to decomposition in the presence of light, heat, or alkali. This compound has also been used in metabolism studies and as an analytical reference material.
Fórmula:C48H50N12O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:874.99 g/molDefluoro atorvastatin calcium
CAS:Defluoro atorvastatin calcium is a bulk drug that has been approved to be used as an adjunct to diet to reduce elevated cholesterol levels in adults. Defluoro atorvastatin calcium is the desfluoro-enantiomer of atorvastatin, which is a statin that inhibits the enzyme HMG-CoA reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonic acid, which is an early step in the synthesis of cholesterol. The fluoro group on defluoro atorvastatin calcium is not expected to have any significant effect on its potency or metabolic pathways and any impurities are not expected to have any therapeutic effect.Fórmula:C66H70CaN4O10Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:1,119.36 g/molDiclofenac impurity B
CAS:Diclofenac impurity B is a regulatory impurity in the drug Diclofenac, which is a nonsteroidal anti-inflammatory drug. Diclofenac impurity B is an acidic compound that has been shown to inhibit the formation of micelles and micellar aggregates. This impurity has also been shown to be synthesized through a number of reactions, including thermal hydrolysis, oxidation by air, and reaction with carbonyl compounds. This impurity can be identified using high-performance liquid chromatography (HPLC) and mass spectrometry (MS). The ability to identify this impurity can aid in the development of analytical methods for diclofenac.Fórmula:C13H9Cl2NOPureza:Min. 95%Cor e Forma:PowderPeso molecular:266.12 g/molD-Ser(11)-Semaglutide
D-Ser(11)-Semaglutide is a semaglutide impurity. The amino acid at position 11 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Fórmula:C187H291N45O59Peso molecular:4,113.64 g/mol
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