APIs para pesquisa e impurezas
Os Ingredientes Farmacêuticos Ativos (APIs) são as substâncias nos medicamentos responsáveis por seus efeitos terapêuticos. Nesta seção, você encontrará uma ampla variedade de APIs destinados a uso em pesquisa. Esses compostos são essenciais para o desenvolvimento, teste e validação de novas formulações farmacêuticas. Na CymitQuimica, oferecemos APIs de alta qualidade para apoiar a pesquisa em descoberta e desenvolvimento de medicamentos.
Subcategorias de "APIs para pesquisa e impurezas"
- Aminoácidos e Derivados(12.439 produtos)
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- Cetonas e Derivados(2.693 produtos)
- Antibióticos Naturais e Semissintéticos(6.406 produtos)
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- Derivados de Quinazolina e Quinolina(66.194 produtos)
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- Esteroides e Derivados(4.986 produtos)
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- Terpenoides e Derivados(3.860 produtos)
- Tiazolidinedionas e Tiopiranos(2.755 produtos)
- Compostos β-Adrenérgicos(231 produtos)
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Foram encontrados 66898 produtos de "APIs para pesquisa e impurezas"
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1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3] oxazine-3-butanoic acid sodium
CAS:Fluoxetine is a selective serotonin reuptake inhibitor that is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa, panic disorder, premenstrual dysphoric disorder (PMDD), and social anxiety disorder. It is also used as an appetite suppressant in some countries. Fluoxetine inhibits the neuronal uptake of serotonin by blocking the presynaptic transporter protein. The most common adverse effects are nausea, diarrhea, drowsiness, dry mouth, blurred vision and sexual dysfunction.Fórmula:C33H35FN2O7•NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:613.63 g/molOlanzapine N-oxide
CAS:Olanzapine N-oxide is a metabolite of olanzapine. It is produced by the oxidative deamination of olanzapine, which is catalyzed by cytochrome P450 enzymes. Olanzapine N-oxide has been shown to be responsible for some of the side effects associated with olanzapine, such as weight gain and sedation. The presence of olanzapine N-oxide in human plasma has been shown to increase with age and in women, which may be due to its higher affinity for α1-acid glycoprotein. Olanzapine N-oxide can be detected in urine or faeces using gas chromatography/mass spectrometry (GC/MS) or liquid chromatography with tandem mass spectrometry (LC/MS).Fórmula:C17H20N4OSPureza:Min. 95%Cor e Forma:PowderPeso molecular:328.43 g/mol3-(3-(Trifluoromethl)phenyl-N-(R)-1-(naphthalen-1-yl)ethyl)prop-2-en-1-amine hydrochloride
CAS:3-(3-(Trifluoromethl)phenyl-N-(R)-1-(naphthalen-1-yl)ethyl)prop-2-en-1-amine is a synthetic compound, which is not found in nature. It is an API impurity and a metabolite of the drug product. It can be synthesized in high purity and with a custom synthesis. 3-(3-(Trifluoromethl)phenyl-N-(R)-1-(naphthalen-1-yl)ethyl)prop-2-en-1-amine has been found to be involved in metabolism studies and research and development, as well as analytical purposes. This compound can also serve as an impurity standard for HPLC analysis.Fórmula:C22H20F3N•HClPureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:391.86 g/molDefluoro atorvastatin calcium
CAS:Defluoro atorvastatin calcium is a bulk drug that has been approved to be used as an adjunct to diet to reduce elevated cholesterol levels in adults. Defluoro atorvastatin calcium is the desfluoro-enantiomer of atorvastatin, which is a statin that inhibits the enzyme HMG-CoA reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonic acid, which is an early step in the synthesis of cholesterol. The fluoro group on defluoro atorvastatin calcium is not expected to have any significant effect on its potency or metabolic pathways and any impurities are not expected to have any therapeutic effect.Fórmula:C66H70CaN4O10Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:1,119.36 g/molN-(2-Amino-4-thiazolyl)acetyl mirabegron
CAS:N-(2-Amino-4-thiazolyl)acetyl mirabegron is a research chemical that belongs to the category of drugs. It is custom synthesized and purified through analytical methods. N-(2-Amino-4-thiazolyl)acetyl mirabegron has been studied for its metabolism in vivo, including its pharmacokinetics and pharmacodynamics. This drug product is a metabolite of mirabegron, an agent used for the treatment of overactive bladder syndrome (OAB). The metabolite is also present in urine and plasma samples.
Fórmula:C26H28N6O3S2Pureza:Min. 95%Peso molecular:536.7 g/molPantoprazole sulphone
CAS:Pantoprazole sulphone is a proton-pump inhibitor that inhibits the production of stomach acid and protects the esophagus from damage. Pantoprazole sulphone has been shown to be effective in treating heart disease patients and reducing their risk of death. It also has biological properties, including modulating the effects of bosentan, which is used to treat pulmonary arterial hypertension. Pantoprazole sulphone has been shown to be chemically stable and stereoselective, which means it binds more strongly to one site than another. Clinical pharmacology studies have found that pantoprazole sulphone has no effect on abomasal motility or gastric emptying time.Fórmula:C16H15F2N3O5SPureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:399.37 g/molOlmesartan EP Impurity C
CAS:Olmesartan medoxomil is a prodrug that is metabolized to the active form, olmesartan, in the liver. The esters of olmesartan medoxomil are metabolized by hydrolysis and by esterases. The most common side effects of olmesartan medoxomil are headache, dizziness, fatigue, nausea and diarrhea. Olmesartan medoxomil is used for the treatment of high blood pressure in adults. This drug also has anti-inflammatory properties due to its inhibition of prostaglandin synthesis.
Fórmula:C29H28N6O5Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:540.57 g/molMolnupiravir Impurity 8
CAS:Produto ControladoMolnupiravir Impurity 8 is an impurity of molnupiravir, a drug product. It is a synthetic chemical compound that has not been found in nature. Molnupiravir Impurity 8 is the result of metabolism studies on the API (active pharmaceutical ingredient) and was observed to be more abundant than other impurities. Molnupiravir Impurity 8 is a white crystalline solid with CAS number 2492423-30-8. It is soluble in water, ethanol, acetone, and chloroform. The purity of this impurity is 99%.Fórmula:C13H19N3O7Pureza:Min. 95%Peso molecular:329.31 g/molN,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate
CAS:N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate (DMNPA) is a synthetic compound with the molecular formula C14H17NO. DMNPA is used as an analytical reference standard for the quantification of N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2thienyl) propanamine HCl by HPLC. DMNPA has been shown to be a metabolite of the drug product, where it is formed from oxidation of the parent drug.Fórmula:C19H21NOS·C4H6O6Pureza:Min. 95%Peso molecular:461.53 g/mol(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
CAS:(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one (FPH) is a synthetic drug product that is used as an impurity standard in the synthesis of pharmaceuticals. It is also used in metabolism studies and research and development. FPH has been shown to be a metabolite of the drug product, 3-(3-fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one, which is classified as an API impurity for pharmacopoeia purposes. FPH has a molecular formula of C11H14FO2N2O and a molecular weight of 222.26 g/mol. The CAS number for FPH is 168828-82-8.Fórmula:C14H17FN2O4Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:296.29 g/molFlumethasone Impurity 12
Flumethasone impurity 12 is a high purity, HPLC standard that is used for research and development. This impurity is an analytical standard that is also used in the drug development process as a pharmacopoeia to measure the purity of an API. Flumethasone impurity 12 can be purchased in various quantities and purities and can be custom synthesized to meet your needs. It has CAS number 511-24-2 and a molecular weight of 306.45 g/mol.Pureza:Min. 95%(R)-5-Hydroxymethyl tolterodine
CAS:(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the liver to its active form, tolterodine. This drug can be used as an alternative for gabapentin in the treatment of detrusor muscle overactivity associated with neurogenic bladder dysfunction. The pharmacokinetic properties of (R)-5-hydroxymethyl tolterodine are similar to those of gabapentin, including the elimination half-life and volume of distribution. However, unlike gabapentin, which has been shown to increase the glomerular filtration rate (GFR) and renal blood flow, there is no evidence that this drug has any effect on GFR or renal blood flow. There is also no evidence that (R)-5-hydroxymethyl tolterodine causes any symptoms that may be attributed toFórmula:C22H31NO2Pureza:Min. 98 Area-%Cor e Forma:Off-White PowderPeso molecular:341.49 g/mol5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic is a drug product that is used for the research and development of drugs. It is manufactured synthetically. This compound has been shown to be metabolized in rats and humans. Studies have also shown that this compound may be an impurity in other drugs. The use of 5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic can be found in the USP/NF as a HPLC standard or as an analytical reference standard.Fórmula:C15H12BrO3NPureza:Min. 95%Peso molecular:334.16 g/molTerbinafine dimer impurity dihydrochloride
CAS:Terbinafine is an antifungal agent that belongs to the family of medicines. It is used to treat fungal infections of the skin, nails and scalp. Terbinafine can also be used to treat other types of fungal infections, such as tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete's foot) and tinea capitis (scalp ringworm). Terbinafine dimer impurity dihydrochloride is a by-product of terbinafine hydrochloride that has been shown to have industrial applications as a dispersant or lubricant in industries such as papermaking.
Fórmula:C36H40N2·2HClPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:573.64 g/molGuaifenesin EP impurity C
CAS:This is a metabolite of guaifenesin, and it is an impurity in the EP guaifenesin. It can be custom synthesized for research and development purposes. The purity of this product is high, and it can be used as an analytical standard or a drug product.
Fórmula:C20H26O7Pureza:Min. 95 Area-%Cor e Forma:Colorless Clear LiquidPeso molecular:378.42 g/mol(S)-5-((tert-Butylamino)methyl)-3-(3-fluoro-(4-morpholinyl)phenyl)oxazolidin-2-one
CAS:(S)-5-((tert-Butylamino)methyl)-3-(3-fluoro-(4-morpholinyl)phenyl)oxazolidin-2-one is a drug product with CAS No. 1215006-08-8, which is a metabolite of Fluoxetine. It is an impurity standard for Fluoxetine and has been used as a reference compound in metabolism studies. (S)-5-((tert-Butylamino)methyl)-3-(3-fluoro-(4-morpholinyl)phenyl)oxazolidin-2-one is also an analytical reagent that can be used to calibrate HPLC systems.Fórmula:C18H26FN3O3Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:351.42 g/mol1-β-D-Ribofuranosyl-3-guanylurea picrate
CAS:Produto Controlado1-beta-D-Ribofuranosyl-3-guanylurea picrate is also known as 1-(diaminomethylene)-3-(beta-D-ribofuranosyl)urea picrate, 1-amidino-3-b-D-ribofuranosylurea monopicrate and Azacitidine Related Compound C. 1-beta-D-Ribofuranosyl-3-guanylurea picrate is an impurity generated from the hydrolysis of the drug Azacitidine, available on the market with the trade name Vidaza. Azacitidine is a chemical analogue of cytidine and is used in the treatment of myelodysplastic syndrome.Fórmula:C7H14N4O5•C6H3N3O7Pureza:Min. 95.0 Area-%Cor e Forma:PowderPeso molecular:463.31 g/mol4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid
CAS:4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid is a white to off-white solid that is soluble in water. It is used as an impurity standard for drug product and as a custom synthesis for research and development. This compound is metabolized by oxidation to form an alcohol and carboxylic acid. The oxidation products are excreted in the urine. 4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid has been used for metabolism studies with human liver microsomes.Fórmula:C20H38CaN2O11Pureza:Min. 95%Peso molecular:522.6 g/molPravastatin lactone
CAS:Pravastatin lactone is a prodrug of pravastatin that is hydrolyzed in vivo to its active form. It is used for the treatment of bowel disease and has been shown to have concentration-time curves that are linear and dose-dependent. Pravastatin lactone has an acidic pH, which may be due to the presence of carboxyl groups on the molecule. This drug also inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, which is an enzyme that catalyzes the conversion of HMG CoA to mevalonate in order to produce cholesterol. Pravastatin lactone also suppresses the production of fatty acids by inhibiting their synthesis at the level of acetyl-coenzyme A (acetyl-CoA). The drug has not shown any evidence of toxicity when administered to rats at doses up to 10 mg/kg body weight per day
Fórmula:C23H34O6Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:406.51 g/mol3-Amino-4,6-dihydro-1,2,6-thiadiazine-1,1-dioxide, hydrochloride
3-Amino-4,6-dihydro-1,2,6-thiadiazine-1,1-dioxide is an impurity that has been identified in the process of synthesizing a drug. The impurity is typically found in small quantities and is not expected to have any adverse effects on the drug product if present in concentrations below 0.1% (w/w). 3-Amino-4,6-dihydro-1,2,6-thiadiazine-1,1-dioxide can be synthesized from two other compounds: 4,6-Diaminohexane and thiosemicarbazide. The CAS number for this impurity is 53497–14–8.Fórmula:C3H8ClN3O2SPureza:Min. 95%Peso molecular:185.63 g/mol
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