APIs para pesquisa e impurezas

<p>M02322 - Parthenolide</p>

<p>Applications p-(Dimethyl-d6-amino)nitrosobenzene is labelled p-(Dimethylamino)nitrosobenzene (D2907600 which is an intermediate in the synthesis of Meldola Blue (M215120), a biosensor for the measurement of lactate in serum.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vinothkumar, S.P., et al.: J. Pharma. Res., 3, 1371 (2010); Huang, R., et al.: Chem. Res. Toxicol., 21, 659 (2008);<br></p>

<p>Stability Hygroscopic<br>Applications Guanethidine Monosulfate acts as an antihypertensive; antiglaucoma<br>References Al-Shora, H., et al.: Int. J. Pharm., 47, 209 (1988), Golander, Y., et al.: J. Pharm. Sci., 77, 902 (1988),<br></p>

<p>Applications The major human labelled metabolite of Flurazepam. Controlled substance.<br>References Ochs, H.R. , et al.: Pharmacology, 36, 166 (1988), Capello, S., et al.: Drug Metab. Dispos., 18, 190 (1990),<br></p>

<p>Applications Bis(3-aminopropyl-d6)amine (CAS# 1219805-55-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Chloro-2,4-dinitrobenzene-d3 (CAS# 347840-12-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Simvastatin-d11 (2,2-dimethylbutyrate-d11) (CAS# 1002347-74-1) can be used to treat hypercholesterolemia and heart disease. This compound can also be used to treat various diseases by preparing it as HMG-CoA reductase inhibitor.<br>References Czarnik, A., U.S Pat.Appl.Publ., 8,(2008); Gant, T., et.al., PCT Int.Appl.,88,(2008);<br></p>

<p>Applications 4-Androsten-11beta-ol-3,17-dione-2,2,4,6,6,16,16-d7 is a useful isotopically labeled compound of 4-Androsten-11β-ol-3,17-dione (A637705)<br></p>

<p>Stability Hygroscopic<br>Applications Antihypertensive; antiglaucoma<br>References Al-Shora, H., et al.: Int. J. Pharm., 47, 209 (1988), Golander, Y., et al.: J. Pharm. Sci., 77, 902 (1988),<br></p>

<p>Applications N-[(2R)-2-Hydroxy-2-(3-hydroxyphenyl)ethyl]-N-methyl-glycine is an impurity of Phenylephrine (P320640), an α-Adrenergic agonist. Mydriatic; decongestant.<br>References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 86, 284 (1946), Gaglia, C.A., et al.: Anal. Profiles Drug Subs., 3, 483 (1974)<br></p>

<p>Applications 3,4-Difluoroaniline-2,6-d2 (CAS# 1061566-62-8) can be used in its derivative form as an antiviral agent for Hepatitis B.<br>References Qiu, Y.L., et.al., U.S. Pat. Appl. Publ., 187,(2019);<br></p>

<p>Applications A di-substituted resorcinol as skin-lightening agents. Used to reduce skin mutation and DNA damage.<br>References Masse, M., et al.: Int. J. Cosmet. Sci., 4, 235 (1982),<br></p>

<p>Applications A possible metabolite of Ranolazine (R122500).<br></p>

<p>Applications Ethyl-d5 4-Aminobenzoate (CAS# 1219803-76-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications An intermediate in the syntheis of a metabolite of the anti-cancer drug Tamoxifen.<br></p>

<p>Applications 5beta-Androstan-3alpha,17beta-diol-2,2,3,4,4-d5 (CAS# 1224710-37-5) is a useful isotopically labeled research compound. This compound can be used to detect androgen, estrogen, progestagen abuse in bovine samples using multi-residue urinary assay.<br>References Scarth, J.et.al., Chromatographia, 71,241-252,(2010);<br></p>

<p>Applications 5alpha-Androstan-17alpha-methyl-17beta-ol-3-one-2,2,4,4-d4 is a useful isotopically labeled compound of Mestanolone (M225790)<br></p>

<p>Applications Testosterone Palmitate-d31 is the labeled analogue of Testosterone Palmitate (T155140) which is found in male serum.<br>References Addo, S.B., et. al.: Steroid, 54, 257 (1989)<br></p>