APIs para pesquisa e impurezas

<p>Tc 1698 dihydrochloride is a tumor-promoting agent that inhibits the growth of tumor tissues. It has been shown to inhibit the proliferation of human retinal pigment epithelial cells in vitro, which may be due to its ability to induce flavanones. Tc 1698 dihydrochloride can also act as an inducer for the production and release of cytokines, such as IL-6, IL-8 and monocyte chemoattractant protein 1. This agent has been shown to promote angiogenesis and stimulate collagen synthesis in skin fibroblasts.</p>

<p>Rocuronium EP Impurity G is a drug product that contains an impurity of Rocuronium EP. It is a synthetic, high purity HPLC standard with a purity greater than 99.5% and a CAS number of 119302-20-4. This compound has been researched for use in the development of drugs to treat conditions such as pain, anxiety, and depression. Rocuronium EP Impurity G is a metabolite that has been found in human urine after administration of rocuronium bromide. The metabolism of this substance has not been fully elucidated yet but it may be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid.</p>

<p>Mdl 72832 hydrochloride is a ligand that modulates the activity of nerve cells. It has been shown to activate and synergistically enhance the effects of nerve growth factor (NGF) and acetylcholine on neurons. Mdl 72832 hydrochloride also increases the synthesis and release of melanocortins, which are neurotransmitters that are involved in regulating appetite, mood, and pain sensation. Mdl 72832 hydrochloride may be a potential nootropic agent for the treatment of neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease.</p>

<p>Anhydro galanthamine is a drug product that is custom synthesized to meet the needs of researchers. The purity of this compound can range from 99% to 99.99%. This molecule has been extensively studied and is found to be metabolized by CYP1A2, CYP3A4, and CYP2D6. Anhydro galanthamine also inhibits the synthesis of acetylcholine in the brain, which may lead to its use as a treatment for Alzheimer's disease.</p>

<p>9-Bromo-6,11-dihydro-8-hydroxy-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile is an analytical standard for HPLC. It is a metabolite of the drug product BROMAZEPAM, CAS No. 1256579-06-2. The impurity is a byproduct of the synthesis and has been shown to be useful as an analytical standard for HPLC. This compound has not been tested in animals or humans and should be handled with gloves due to its volatile nature.</p>

<p>Please enquire for more information about Carbidopa 4-phosphate trihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Amino-1-naphthaleneacetic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sulfo EGS is a potent analog that has shown promising anticancer activity in various human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in the regulation of cellular processes such as proliferation, differentiation, and apoptosis. Sulfo EGS has been found to be particularly effective against Chinese hamster ovary cells and tumor cells from medicinal plants. This inhibitor also shows potential for use in the development of kinase inhibitors for cancer therapy. In addition, Sulfo EGS is commonly used as a cross-linking reagent to covalently link proteins or protein complexes in urine or other biological samples for further analysis. Overall, Sulfo EGS is an important tool for cancer research and drug development.</p>

<p>Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside is an impurity of Dapagliflozin.</p>

<p>Oxolamine citrate salt is a pharmaceutical drug used for the treatment of scleroderma. It acts as an iron chelator and inhibits the production of the cytotoxic agent, podophyllotoxin, by inhibiting its conversion to epipodophyllotoxin. Oxolamine citrate salt has been shown to have a beneficial effect on Alzheimer's disease and may have therapeutic potential in other neurological diseases such as Parkinson's disease. The compound has been shown to inhibit acetonitrile-induced hyperactivity in mice. Oxolamine citrate salt has also been found to be effective against Pseudomonas aeruginosa and Staphylococcus aureus isolates that are resistant to oxacillin, ginkgetin, or pseudoephedrine. This drug can be analyzed using liquid chromatography with an acetonitrile gradient and a hypersil C18 column.</p>

<p>1-Isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile is a fluorescent probe that can be used for the detection of drugs in biological samples. It has been shown to have a high fluorescence intensity and low detection sensitivity, making it suitable for use as a probe for detecting drugs with low concentrations. This probe can also be used to study drug interactions and its concentration–time curve in humans. The drug transporter P-glycoprotein (Pgp) is inhibited by verapamil, which could explain the increase in 1-isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile's detection sensitivity.</p>

<p>Ethyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate is an analytical standard used to identify impurities in drug products. It is a metabolite of the drug product and has been shown to be safe for human consumption. The compound is a synthetic chemical that is not found naturally in the environment. CAS No. 180468-42-2</p>

<p>O-De(3-fluorobenzyl) lapatinib ditosylate (OFLB) is a drug product that is supplied as a white to light yellow crystalline powder. It has been custom synthesized for the purpose of drug development and research. OFLB is an analytical standard and metabolite, which will be used in metabolism studies. This product is not intended for use in humans or animals.</p>

<p>Amlodipine besilate impurity A is a low-energy impurity that is formed in the crystallization process. It is an amide compound that has a hydrogen bond with crotonic acid and amlodipine, and can be found in acidic environments. The structural formula for this impurity is C8H14NO2S·C4H6O4·CH3OH.</p>

<p>2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran is a benzofuran. It is a yellow solid that can be dissolved in water and alcohol.</p>

<p>Torasemide Impurity E is a drug product that belongs to the group of impurities. It is a natural product and can be found in the environment. Torasemide Impurity E has been shown to inhibit bacterial growth in vitro and also antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus. Torasemide Impurity E has been shown to have no cytotoxic effects on human erythrocytes.</p>

<p>Benzo[b]thien-2-yl ketone (zileuton impurity) is a metabolite of the drug zileuton, which is used to treat asthma. Benzo[b]thien-2-yl ketone is formed by the oxidation of benzo[b]thiophene in the presence of cytochrome P450 enzyme system. It has been found to have anti-inflammatory properties and may be useful for treating asthma. This product is available as an analytical standard for HPLC, or as a custom synthesis for research and development.</p>

<p>Pronethalol is a non-steroidal anti-inflammatory drug (NSAID) that has been shown to be effective against primary sclerosing cholangitis and chronic inflammatory bowel disease. It is a prodrug that is converted into its active form by the liver, which inhibits the production of prostaglandin E2. Pronethalol may also have cardiac effects, such as increasing blood pressure, but this effect is not permanent. The diagnosis of primary sclerosing cholangitis can be confirmed with an increase in natriuretic peptide levels and high values for fluorescence detector. Long-term efficacy of pronethalol has been demonstrated in some cases. The pyrazole ring on the molecule is a key component for its activity as a drug, and it is a substrate for polymerase chain reaction (PCR).</p>

<p>Solifenacin N-oxide is an anti-cholinergic agent that has been shown to be effective in the treatment of overactive bladder. Solifenacin N-oxide is a prodrug that is hydrolyzed in vivo to solifenacin, its active form. The compound reversibly binds to muscarinic receptors and inhibits the release of acetylcholine. Solifenacin N-oxide has been shown to have low levels of impurities and is highly soluble in water. It was also found to be stable when stored at room temperature for two months. This drug has a high flow rate and moderate retention time, which makes it suitable for reversed-phase liquid chromatography (RPLC). RPLC is a chromatographic technique that separates compounds by size, hydrophobicity, or charge.</p>

<p>Impurity F is a metabolite of Fexofenadine. It is an impurity that can be found in the drug product and is used as a research and development standard for impurities. Impurity F has been shown to be a metabolite of Fexofenadine in human liver microsomes, and this metabolite has also been shown to have antihistamine properties. This impurity is used as a pharmacopoeia reference standard for HPLC analysis of fluoroquinolones, but it does not have any therapeutic value.</p>

<p>Please enquire for more information about 4-Hydroxy guanabenz hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Aurantinidin chloride is a molecule that has been shown to inhibit the growth of prostate cancer cells in vitro. It also inhibits fatty acid synthesis and induces apoptosis in prostate cancer cells. Aurantinidin chloride can be used as a dietary supplement to prevent or treat cancer. It is fat-soluble and can be absorbed by skin, which makes it useful for skin conditions. Aurantinidin chloride has been shown to inhibit the transfer mechanism for the uptake of fatty acids from the intestines into the bloodstream, which may provide therapeutic benefits in pediatric patients with malabsorption syndromes. Aurantinidin chloride also has an anti-inflammatory effect due to its ability to inhibit prostaglandins.</p>

<p>Moncrotophos is an anticancer agent that has been shown to inhibit the activity of kinases, enzymes that play a crucial role in cell growth and proliferation. This inhibitor has been found to induce apoptosis, or programmed cell death, in cancer cells. Moncrotophos is a synthetic analog of ghrelin, a hormone that regulates appetite and energy balance in humans. It has been shown to have potent inhibitory effects on tumor growth in animal models and human cancer cell lines. In addition to its anticancer properties, Moncrotophos has also been investigated as a potential treatment for other diseases such as diabetes and obesity due to its ability to regulate glucose metabolism. However, caution should be exercised when using this product as it can be toxic if not used properly.</p>

<p>2-Demethoxy-4-methoxy urapidil is a drug product that is used in the development of new drugs. It is a synthetic compound that is metabolized to form its natural metabolite, 2-demethoxyurapidil. This impurity standard has been shown to have anti-inflammatory effects and can be used as an API impurity for pharmacopoeia. 2DMO4MU has been shown to be useful in the study of metabolism and has been found to inhibit prostaglandin synthesis.</p>

<p>Oseltamivir is an antiviral drug that prevents the replication of influenza viruses in the body. It is a prodrug, which means it must be converted to its active form in vivo by hydrolysis. Oseltamivir is metabolized to oseltamivir acid by the enzyme amidase, which is found in the gastrointestinal tract. Oseltamivir acid inhibits the neuraminidase enzyme, which allows viral particles to attach to and invade cells. Oseltamivir acid has a low dosage, so it can be taken orally with or without food and does not require intravenous administration. This drug also has a low toxicity profile and can be given at low dosages for long periods of time without significant side effects such as kidney problems or bone marrow suppression.</p>

<p>1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is a metabolite of carvedilol. It is not active as a drug, but may have pharmacological effects. 1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is used as an impurity standard for HPLC analysis of carvedilol in the pharmaceutical industry.</p>

<p>D-Threo-3,4-dihydroxyphenylserine hydrochloride is a potent inhibitor that has been shown to induce apoptosis in various cancer cell lines. It works by inhibiting kinases and proteins involved in the cell cycle, resulting in the inhibition of tumor growth. This compound has been extensively studied for its anticancer properties and has shown promising results in human clinical trials. D-Threo-3,4-dihydroxyphenylserine hydrochloride is derived from Chinese medicinal herbs and can be isolated from urine or synthesized chemically. Its ability to selectively inhibit cancer cell growth makes it a potential candidate for future cancer therapies.</p>

<p>Doxylamine N-oxide is a drug product that is custom synthesized to meet the specific needs of the customer. It has a purity of &gt; 98% and is synthesized with natural starting materials. Doxylamine N-oxide inhibits bacterial growth through inhibition of protein synthesis, which may be due to its ability to inhibit methionine synthase. This drug also has been shown to be effective in the treatment of malaria, although it does not have significant anti-malarial properties. Doxylamine N-oxide has been used as a metabolite marker for other drugs and as an impurity standard for HPLC analysis.</p>

<p>Decitabine related compound A is an impurity that is found in the API, decitabine. It is an analytical standard for HPLC measurements and a reference material for impurity testing. It is also used as a pharmacopoeia standard for pharmacopoeias such as European Pharmacopoeia, USP, and Japanese Pharmacopoeia. Decitabine related compound A has been synthesized from natural sources such as plant-derived alkaloids and synthetically produced in the laboratory. CAS No. 1019659-87-0</p>

<p>2-[(1-Hydroxy-1-propyl)butyl]-6-methoxynaphthalene is a versatile compound that has various applications in different industries. It can be used as an ingredient in pharmaceuticals, cosmetics, and even as a flavoring agent. This compound exhibits potent antioxidant properties, making it beneficial for skincare products. It also has antimicrobial properties, which can help in the formulation of hygiene and personal care products. Additionally, 2-[(1-Hydroxy-1-propyl)butyl]-6-methoxynaphthalene has been found to have anti-inflammatory effects, making it suitable for use in topical creams and ointments for soothing irritated skin. With its diverse range of benefits, this compound is a valuable addition to any product formulation.</p>

<p>1-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]-7-hydroxy-1,2,3,4-tetrahydro-carbostyril (1HHC) is a synthetic drug that is used as a research tool in the study of metabolism. It has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 1HHC also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one is a synthetic compound that has been used as an impurity standard. This substance is also found in the drug product Loxapine (Loxitane) and is metabolized to the active ingredient loxapine. 5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one has not been shown to have any therapeutic effects.</p>

<p>Please enquire for more information about 1,4-Bis(trichloromethyl)-2,5-dichlorobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethylene terephthalate cyclic hexamer-d24 is a synthetic drug product. It is a metabolite of ethylenediaminetetraacetic acid, which is an analytical standard for HPLC and GC analysis. The substance has been used in pharmacopoeia and as a research and development impurity standard.</p>

<p>Amoxicillin EP Impurity G is an impurity of Amoxicillin. It is a white to off-white crystalline powder with a melting point of 178 °C. The compound is soluble in alcohol, chloroform, ether, and acetone. This product can be used as an analytical standard for the drug development, niche drug product, or custom synthesis of the drug. Impurity G has been shown to have pharmacopoeia purity and natural origin. It can also be used as an impurity standard for HPLC analysis and pharmaceutical testing.</p>

<p>Rel-(3R,5R)-fluvastatin sodium is an impurity standard of fluvastatin that is used in the development of new drugs. The substance has been shown to inhibit cholesterol synthesis by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase and is a potent inhibitor of cholesterol biosynthesis. Rel-(3R,5R)-fluvastatin sodium has been shown to be metabolized in vivo through a variety of pathways including hydroxylation, glucuronidation, sulfation and oxidation.</p>

<p>The 1-aza-8-hydroxy-6-oxo-oct-2-en-1-oylimidazole is a prodrug that is hydrolyzed to form the active compound clavulanate. It can be used for the treatment of infections caused by beta lactamase producing bacteria such as penicillinase producing staphylococci and beta lactamase producing streptococci. The 1-(4-Aza)8-(6-oxo)oct-(2)en-(1)-oylimidazole binds to penicillin binding proteins, which prevents the formation of an antibiotic inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. The clavulanic acid moiety in this drug also inhibits beta lactamases produced by bacteria, resulting in increased efficacy against these organisms.</p>

<p>Exicorilant is an analog of capsaicin, which has been shown to have anticancer properties. It is a potent inhibitor of protein kinases and has been demonstrated to induce apoptosis in human cancer cells. Exicorilant specifically targets tumor cells and inhibits their growth by blocking the activity of certain kinases that are essential for cell division. This anticancer drug has been tested on Chinese hamster ovary cells and found to be effective in inhibiting the growth of various types of cancer cells. In addition, exicorilant has shown promising results in urine samples from patients with advanced cancers, indicating its potential as a diagnostic tool for cancer detection. Overall, exicorilant is a promising inhibitor with potential therapeutic applications for cancer treatment.</p>

<p>Pioglitazone is a thiazolidinedione antidiabetic agent that is used to treat type 2 diabetes. Pioglitazone has been shown to have the potential to attenuate insulin resistance and decrease hepatic glucose output. Pioglitazone has also been shown to inhibit many of the enzymes involved in the metabolism of glucose, such as glucokinase, phosphoenolpyruvate carboxykinase, and pyruvate dehydrogenase. In addition, pioglitazone has been shown to increase insulin sensitivity by increasing the number of insulin receptors on cell membranes. Pioglitazone has also been shown to reduce blood pressure through its effects on erythropoietin activity and nitric oxide production. This drug may act as an antioxidant by inhibiting peroxidation of lipids in the liver.<br>Pioglitazone has also been studied for its effect on nervous system diseases, such as Alzheimer's disease and X</p>

<p>Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that is used for the relief of inflammation and pain in osteoarthritis and rheumatoid arthritis. It is a stable, water-soluble prodrug of methylated meloxicam. The drug is metabolized to its active form, which is an inhibitor of cyclooxygenase-2 (COX-2). Meloxicam has been shown to be effective against COX-1, but not COX-2. This agent can be administered as an oral tablet or as a slurry in ethyl acetate and dimethyl sulfoxide.</p>

<p>a-(Aminocarbonyl)-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzeneethanesulfonic acid is an analytical standard that is used in the drug development process. It has a purity of 99.9% and is used as an HPLC standard, niche product, and pharmacopoeia impurity. This chemical can also be custom synthesized or found in nature.</p>

<p>Chlorthalidone impurity A is an impurity in Chlorthalidone. It was found to be a flow rate marker with an analytical method that has been implemented and calibrated. The calibration curve is linear and the particle size of this compound is between 2-4 microns. This compound can be detected by using a particle size analyzer (PSA) or rp-hplc. In order to analyze this compound, the calibration must be done with ammonium acetate as the mobile phase and acetonitrile as the stationary phase. The wavelength for detection is 220 nm and the runtime is 1 minute. Analytical methods such as chromatographic methods, ultraviolet spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectroscopy may also be used to identify this compound.</p>

<p>Please enquire for more information about N-Carboxylate-6-hydroxy melatonin ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Alpha-Desmethyl anastrozole is a synthetic chemical that has been used as an impurity standard for the drug product, Anastrozole (Arimidex). This compound is metabolized in humans and is a metabolite of Arimidex. Alpha-Desmethyl anastrozole exhibits high purity and can be synthesized using custom synthesis. The CAS number for this compound is 1215780-15-6.</p>

<p>Isoginsenoside Rh3 is a metabolite of the natural product ginseng. It has been reported to have anti-inflammatory properties in vitro and in vivo, but it has not been studied extensively. Isoginsenoside Rh3 is not found in the human body, but it is an impurity of Ginseng extract that is routinely measured by HPLC. The concentration of this metabolite can be used as a quality control measure for Ginseng extracts.</p>

<p>Methyl 6-phenyl-5-(p-tolyl)picolinate is a metabolite that is produced when the drug phenacetin (acetanilide) is broken down in the body. It has been used as a standard for HPLC, as well as an impurity in certain drugs. This compound has been shown to be a nicotinic acetylcholine receptor agonist, and it has been used to study the pharmacological properties of this receptor.</p>

<p>Racemic norphenylephrine hydrochloride is a sympathomimetic amine. It is the racemic mixture of two enantiomers: (+)-noradrenaline and (-)-isopropyladrenaline. Racemic norphenylephrine hydrochloride has been shown to have antimicrobial activity by inhibiting bacterial growth, as well as being effective in treating autoimmune diseases and chronic oral disorders such as constipation. Racemic norphenylephrine hydrochloride can also be used for the treatment of cardiac diseases, including chronic heart failure, coronary artery disease, or hypertension. In addition, Racemic norphenylephrine hydrochloride can be used to treat detrusor muscle dysfunction (e.g., urinary incontinence).</p>

<p>Fluorometholone delta 9,11 is a drug product that is used as an analytical reference standard for the quantitative determination of impurities in drugs. It is a natural metabolite and impurity in synthetic drugs such as fluoroquinolones and corticosteroids. Fluorometholone delta 9,11 has been shown to be a substrate for CYP3A4 and P-glycoprotein. This drug has also been shown to have anti-inflammatory effects and may decrease the risk of infection by suppressing neutrophil function.</p>

<p>4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a synthetic drug product that has been purified to high purity. This compound is used as an analytical standard and impurity in the development of drugs. 4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a metabolite of imidazole, which is a natural substance with unknown pharmacological activity. It has been found to be an impurity in the synthesis of various pharmaceuticals, including metronidazole and ampicillin. This product has not yet been evaluated for safety or efficacy in humans.</p>

<p>1,3-bis(1,1-Dimethylpropyl) benzene is a synthetic compound that is used in drug product formulation. It is also used as an analytical standard for the determination of 1,3-bis(1,1-dimethylethyl)benzene in drug products and as a natural impurity in API preparations. This compound is metabolized to 1,3-dibromobenzene and 1,2-dibromoethane during its metabolic process. The chemical properties of this compound are similar to those of other alkylbenzenes and it has been shown to have pharmacological effects such as analgesic and antiinflammatory activities.</p>

<p>Please enquire for more information about Glimepiride EP Impurity J hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-[4-(Methylsulfonyl)-1-piperazinyl]-1,2-benzisothiazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tortoside A is a potent inhibitor of protein kinases and has been found to have anticancer properties. It is an analog of a compound originally isolated from a Chinese medicinal plant. Tortoside A has been shown to induce apoptosis in cancer cells by inhibiting the activity of specific kinases that are involved in tumor growth and progression. This compound has also demonstrated promising results as an anticancer agent, with studies showing its ability to inhibit the growth of various human cancer cell lines. Tortoside A can be detected in urine, making it a potential biomarker for monitoring cancer treatment efficacy. Its unique properties make it an exciting candidate for further research and development as a potential cancer therapy.</p>

<p>2-[3,5-Dichloro-4-[(4-chlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione is a research and development impurity standard. It is custom synthesized for drug product synthesis and analysis. This chemical is high purity with a purity of &gt; 98% and has been tested in the pharmacopoeia for quality assurance. 2-[3,5-Dichloro-4-[(4-chlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione can be used as a metabolite marker in metabolism studies due to its structural similarity to the parent compound.</p>

<p>Erythromycin E is a diluent that is used to make erythromycin solutions. It has been shown to have bioactive molecules by incubating it with chromatographic methods. These bioactive molecules are conjugates of erythromycin and methyl ethyl groups. Erythromycin E has also been shown to have genetic mechanisms, which may relate to its ability to inhibit the synthesis of inflammatory cytokines such as IL-1β and IL-8 in the airways. The acetate extraction method is used for the production of erythromycin E. This process involves extracting erythromycin from Streptomyces bacteria grown in an acetate buffer solution.</p>

<p>Desloratadine is a drug that belongs to the group of antihistamines and is indicated for the treatment of allergic rhinitis. It has been shown to be as effective as loratadine, cetirizine, and fexofenadine in clinical trials. Desloratadine is metabolized by cytochrome P450 enzymes including CYP2D6 to its active form, desloratadine N-oxide. The metabolites are excreted in the urine.</p>

<p>N-Formyl-L-leucine (1R)-1-[[(2R,3R)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester is an impurity standard for HPLC. It is a synthetic compound that has been custom synthesized to meet the requirements of a pharmacopoeia. This product is offered in a high purity and can be used for drug development and research and development.</p>

<p>Chrysamide B is an analog that has been shown to have potent anticancer properties. It induces apoptosis in human cancer cells by inhibiting kinases such as cyclin-dependent kinase and protein kinase. Chrysamide B has been found to be a potent inhibitor of tumor growth in Chinese hamster ovary cells and is being studied for its potential use as an anticancer drug. This compound has also been detected in human urine, suggesting that it may have potential as a biomarker for cancer diagnosis or treatment monitoring. The unique mechanism of action of Chrysamide B makes it a promising candidate for the development of novel cancer therapies and inhibitors.</p>

<p>Duloxetine is a drug product that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors. Duloxetine is a metabolite of duloxetine phenyl carbamate, which is an impurity standard for HPLC analysis. Duloxetine has been shown to inhibit the metabolism of serotonin and norepinephrine in the brain, leading to increased amounts of these neurotransmitters. This medication has been studied in niche populations such as those with depression and diabetic neuropathy. Duloxetine also has high purity standards, meeting the requirements of pharmacopoeia.</p>

<p>2-[3,5-Dichloro-4-(4-chlorobenzoyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione is a research and development impurity standard. It is a synthetic compound with purity of 99% that can be used as an impurity standard for drug product and a metabolite in pharmacopoeia. 2-[3,5-Dichloro-4-(4-chlorobenzoyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione has been used in metabolism studies to demonstrate the formation of 2-[3,5-dichloro-4-(4-fluorobenzoyl)phenyl]-1,2,4-triazine 3,5(2H, 4H)-dione.</p>

<p>2,3-Dimethylphenyl mefenamic acid is a synthetic drug product. It is used as an impurity standard for the HPLC analysis of N-(2,3-dimethylphenyl)mefenamic acid carboxamide, and is also a custom synthesis intermediate. 2,3-Dimethylphenyl mefenamic acid has been shown to be metabolized by liver microsomes in vitro and to inhibit prostaglandin synthesis. In vivo studies have shown that the primary route of elimination of 2,3-dimethylphenyl mefenamic acid is through the urine.<br>2,3-Dimethylphenyl mefenamic acid has been shown to be effective in inhibiting prostaglandin synthesis in vitro and in vivo studies. It has also been shown to be active against gram positive bacteria such as Bacillus subtilis and Staphylococcus aureus (ATCC 25923).</p>

<p>Ciprofloxacin impurity D hydrochloride is a drug product that is an analytical standard. It is also a natural impurity found in Ciprofloxacin. This compound has been synthesized and manufactured to be used as an impurity standard. It exhibits the same physical, chemical, and biological properties as Ciprofloxacin. The CAS number for this substance is 526204-10-4. Impurities such as Ciprofloxacin impurity D hydrochloride may be present in the finished drug product if they are not removed during the manufacturing process. Chemical reactions may also lead to the formation of these substances. The presence of these substances can affect the quality of the drug product and may lead to adverse effects for patients who use them.<br>CAS No.: 526204-10-4<br>Molecular Weight: 258.25<br>Formula: (C8H6ClF2NOS)</p>

<p>Methyl 6-(1-hydroxyethyl)-3-methyl-4-phenylpicolinate is a synthetic chemical that is used as an analytical standard in chemical and pharmaceutical research. It has been shown to have a wide range of pharmacological effects, including antihypertensive, antidiabetic, and antiulcerogenic activities. Research into the drug product is ongoing.</p>

<p>NBI 27914 hydrochloride is a small molecule that binds to and blocks the neurotransmitter receptor for norepinephrine, which is involved in the regulation of mood. This drug has been shown to have anxiolytic-like effects in animals and may be useful for treating anxiety disorders that are due to congenital adrenergic hyperactivity. NBI 27914 hydrochloride also has an anxiogenic effect at high doses, which may be due to its ability to bind and block beta-adrenergic receptors. It is also able to act as a specific agonist or antagonist of alpha-adrenergic receptors.</p>

<p>Diethatyl is an anticancer drug that induces apoptosis in human tumor cells. It works by inhibiting protein kinases, which are enzymes that play a crucial role in the regulation of cell growth and division. Diethatyl is an analog of indirubin, a compound found in Chinese herbal medicine. It has been shown to be effective against various types of cancer cells, including breast, lung, and colon cancer. Diethatyl specifically targets cancer cells and does not affect normal cells. It is a promising new inhibitor in the fight against cancer.</p>

<p>Pravastatin 6-oxo Impurity is an impurity of Pravastatin, a drug used in the treatment of high cholesterol. The impurity has been identified through analytical methods and is characterized by HPLC analysis. This substance has been shown to be present in at least 0.1% of the drug product and may be present as a result of incomplete synthesis or a side-reaction during synthesis.</p>

<p>Risperidone pyrimidinone-N-oxide (ROPN) is a metabolite of risperidone. It is an impurity that is used as a reference standard for HPLC in the drug development process. ROPN can be synthesized from risperidone, but it is also found naturally in some plants and fungi. It has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>Desoxyquinocetone is a specific antibody that recognizes and binds to the quinoline ring of desoxyquinocetone. It has low bioavailability in the body, which is determined by the structural formula. The detection sensitivity of this antibody is high, and it can be used in tissue samples. This antibody also has a chromatographic method for determining carbonyl reduction and a monoclonal antibody for hybridoma cell strain. The specificity of this antibody is determined by the target tissue and strain, as well as its chromatographic method for detecting antigen.</p>

<p>Cefotaxime sodium impurity C is a by-product of the synthesis of cefotaxime. It is an impurity standard for drug product, custom synthesis and research and development. The CAS number for this substance is 66403-32-5. This compound has been shown to be a metabolite in metabolism studies. Impurity standard compounds are used in analytical methods such as HPLC.</p>

<p>Pinaverium bromide impurity 11 is a drug product that is used in the development of new drugs. It is an analytical standard for pharmacopoeia and research purposes. The chemical name for Pinaverium bromide impurity 11 is 2-Bromo-6-nitrobenzimidazole, CAS No. 1970218-70-2, which can be found in the NIST Mass Spectral Library. This compound has a molecular weight of 226.12 and melting point of 191°C (decomposes). It has been custom synthesized by our company to meet the requirements of customers who need this specific impurity for their drug development or research and development.</p>

<p>5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).</p>

<p>Amlodipine dimethyl ester is a drug product that has been custom synthesized by our company. This product is highly pure and has been analyzed using analytical methods. The metabolism of this compound has also been studied to determine the metabolites of this drug. Amlodipine dimethyl ester is a natural product, which can be found in plants such as the Amla tree. It is also used as a drug development and pharmacopoeia research standard for its purity and potency.</p>

<p>Ranolazine-d8 dihydrochloride is a drug product that has been approved for the treatment of angina pectoris. Ranolazine is a drug that belongs to the class of antianginal drugs. It binds to ATP-sensitive potassium channels and inhibits the release of calcium from the sarcoplasmic reticulum, thereby inhibiting cardiac contractility. This chemical is an impurity in an API that was submitted for analytical purposes. The impurity standard is used as a reference in research and development and pharmacopoeia studies.</p>

<p>Rapamycin is a natural product from Streptomyces hygroscopicus. It has been shown to inhibit T- and B-lymphocyte proliferation, induce apoptosis of lymphocytes, and suppress both humoral and cell-mediated immune responses. Rapamycin is also an immunosuppressant that decreases the incidence of rejection in organ transplant patients.<br>Rapamycin is used as a drug product in the form of a sterile solution for injection. The purity of rapamycin should be at least 99%, with less than 1% impurities, such as 42-O-tert-butyldimethylsilyloxyethyl rapamycin (TBDMS). Rapamycin is not currently available on the market as an API, but it may be custom synthesized for research purposes or for clinical trials.</p>

<p>2,12-Dihydro-1,3-dimethyl-9-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a synthetic compound that has not been evaluated in humans. This compound is an impurity standard for the synthesis of an API. The purity of this compound is &gt;98% and it has been shown to be stable under acidic conditions.</p>

<p>Apitoxin is a natural toxin found in the venom of honeybees. Studies have shown that it has potential anti-cancer properties due to its ability to induce apoptosis, or programmed cell death, in human cancer cells. Additionally, apitoxin contains kinases that can inhibit tumor growth and glycerol analogs that have demonstrated anticancer activity in Chinese hamster ovary cells. Indirubin, a compound found in apitoxin, has been identified as a potent inhibitor of kinases involved in cancer cell proliferation. Apitoxin may also be useful as a urinary biomarker for detecting prostate cancer. Overall, the unique properties of apitoxin make it an intriguing candidate for further research into potential cancer treatments.</p>

<p>3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide is an analytical standard, used for HPLC analysis of impurities. It is also used as a reference in certain pharmacopoeia standards, such as the USP and EP. 3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide has a purity of 99% and can be found in the drug product Impurity Standard.</p>

<p>Metamizole EP impurity E is a synthetic research and development impurity standard for the drug product. Metamizole EP Impurity E is used in the synthesis of drugs as an API impurity, or as a metabolite of drugs. The chemical purity is typically greater than 98%. Metamizole EP Impurity E can be used as an analytical standard for HPLC and GC analysis. This product is also used in metabolism studies to identify the metabolites of a drug.</p>

<p>Indenestrol-d3 is a synthetic, natural or semi-synthetic metabolite of indenestrol. It is an impurity in the drug product and is detectable by HPLC. Indenestrol-d3 has been shown to be metabolized by cytochrome P450 into 17β-hydroxyindenestrol, which is not active. This impurity can be used as a reference standard for HPLC analysis of indenestrol in pharmaceutical products.</p>

<p>Please enquire for more information about Fenbufen-d9 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,8,15,22-Tetraazacyclononacosane-2,9,16,23-tetrone is a potent inhibitor of kinases that have been shown to be involved in the growth and survival of cancer cells. This compound was isolated from Chinese urine and has been found to induce apoptosis in cancer cells by inhibiting kinase activity. The analogs of this compound have been developed as anticancer agents due to their ability to inhibit cyclin-dependent kinases (CDKs) that are involved in cell cycle regulation. This inhibitor has shown promising results in preclinical studies for the treatment of various types of tumors, including breast cancer and lung cancer. It is a potential candidate for further development as an anticancer drug due to its high specificity towards human kinases and low toxicity towards healthy cells.</p>

<p>Trans-haloperidol N-oxide is a pyridinium salt that has been used in the synthesis of other compounds. It is an intermediate in the formation of the anion, which arises due to hydrolysis of haloperidol. The anion can be converted to an n-oxide by treatment with hydrogen peroxide and acetic acid. Trans-haloperidol N-oxide can also be prepared by chromatography or kinetic studies. The analytical techniques employed include high performance liquid chromatography (HPLC) and gas chromatography/mass spectrometry (GC/MS).</p>

<p>Diethylstilbestrol monomethyl ether is a drug product that is custom synthesized for the purpose of research and development. This product is made to pharmacopoeia standards and has a purity level of &gt;98%. The analytical data for this product includes HPLC standard, which is used to ensure the quality of the product. Metabolism studies have been conducted on this product, which shows that it has a natural metabolite. Diethylstilbestrol monomethyl ether is also an impurity standard, which means it can be used as reference material in order to test for other substances.</p>

<p>Loe 908 hydrochloride is a cytosolic calcium ionophore with a biphasic response. It activates epidermal growth factor and inhibits myosin phosphatase, inhibiting the activation of the Ras pathway. Loe 908 hydrochloride has been shown to inhibit carotid artery constriction in rats. This drug acts by binding to cation channels in blood vessel walls, which prevents the influx of calcium ions into the cells of the vessel wall. Loe 908 hydrochloride also binds to 5-HT2 receptors and activates them. The result is an increase in intracellular calcium levels and inhibition of adenylyl cyclase, which leads to a decrease in cyclic AMP levels. This leads to decreased contractility in smooth muscle cells and relaxation of arterial smooth muscle cells.</p>

<p>Levofloxacin hydroxy acid is a high purity, drug product with a HPLC standard. It is used for drug development and research. Levofloxacin hydroxy acid has been developed as an analytical reference standard for the detection of impurities in API manufacturing. The pharmacopoeia includes levofloxacin hydroxy acid as an impurity standard. Levofloxacin hydroxy acid is also used in metabolism studies to investigate the role of levofloxacin's active metabolite, M-2, on the activity of CYP2C8 and CYP3A4 enzymes.</p>

<p>Salbutamol Impurity D is a chiral, metal chelator impurity of the drug substance Salbutamol. It is a prodrug that is hydrolyzed to its active form, salbutamol sulfate, in vivo. Salbutamol Impurity D binds to chloride ions and has been shown to be an interferent for many analytical methods. The reversed-phase chromatography retention time for Salbutamol Impurity D is about 10 minutes shorter than for Salbutamol sulfate.</p>

<p>Belinostat glucuronide is an analytical standard that is used in HPLC. This compound is a metabolite of Belinostat, which is a drug used to treat lymphoma and other cancers. Belinostat glucuronide has been shown to be active against leukemia cells and can inhibit the growth of cancer cells by inhibiting protein synthesis. It also inhibits the activity of topoisomerase I, II, and III.</p>

<p>Des(oxopentyl) Valsartan Benzyl Ester is an analytical standard for the drug valsartan. It is a white to off-white, crystalline powder that is soluble in methanol and acetone. This compound can be used as an HPLC standard, or as an impurity standard in the development of valsartan drugs. Des(oxopentyl) Valsartan Benzyl Ester also has niche uses in natural product isolation and synthetic organic chemistry. It is a metabolite of des(oxopentyl)valsartan, which is a prodrug of valsartan.</p>

<p>Impentamine dihydrobromide (IMB) is a research and development drug product that has been synthesized for the treatment of epilepsy. IMB is an impurity standard for impentamine, a synthetic drug that inhibits the enzyme acetylcholinesterase and has been shown to be effective in the treatment of Alzheimer's disease. Impentamine dihydrobromide is a metabolite of impentamine, which inhibits the enzyme acetylcholinesterase and has been shown to be effective in the treatment of Alzheimer's disease. Impentamine dihydrobromide binds to acetylcholinesterase by competitive inhibition and causes an accumulation of acetylcholine in the synaptic cleft. This accumulation leads to increased neurotransmission at nerve terminals, because acetylcholine is necessary for neurotransmitter release.</p>

<p>The 4-chloro-3-hydroxy butanamide is a white crystalline powder that is soluble in water, ethanol, and chloroform. It has an analytical purity of 99.5% and a research and development purity of 99.0%. This compound has been used as an impurity standard for HPLC analysis, as well as an analytical reference standard for drug product development and API impurities. The chemical formula is C7H10ClNO2 with a molecular weight of 164.24 g/mol. CAS No. 226213-72-5. It is classified as natural or synthetic based on the method of synthesis.</p>