Peptídeos
Subcategorias de "Peptídeos"
Foram encontrados 29635 produtos de "Peptídeos"
SARS-CoV-2 Spike (999-1007)
The SARS-CoV-2 spike protein is present on the outside of the virus particles and can bind to angiotensin-converting enzyme II (ACE2) present on the host cells. The C-terminal receptor binding domain (RBD) of the spike protein binds to the N-terminal peptidase M2 domain of ACE2. This receptor binding results in the internalisation of the virus-receptor complex and is, therefore the mechanism of entry of SARS-CoV-2 into host cells.The spike protein residues GRLQSLQTY (999-1007) from C have been identified as a T-cell epitope with a predicted HLA restriction. Immune targeting of confirmed epitopes may potentially offer protection against SARS-CoV-2 and help the development of vaccines for long-lasting immunity.Peso molecular:1,064.6 g/molPalmitoyl pentapeptide 4 acetate
CAS:Palmitoyl pentapeptide 4 acetate is a medicinal compound that has been shown to have anticancer properties. It works by inducing apoptosis, or programmed cell death, in cancer cells. This compound has been used in traditional Chinese medicine to treat various types of tumors. Palmitoyl pentapeptide 4 acetate acts as an inhibitor of kinases, which are enzymes that play a crucial role in the regulation of cell growth and division. It has been shown to be effective against multiple types of cancer cells, including those found in the urine. This compound is an analog of a natural protein kinase inhibitor and is often used in combination with other inhibitors for maximum effect.Fórmula:C39H75N7O10•(C2H4O2)xPureza:Min. 95%Cor e Forma:PowderH-TL^SDYNIQK-OH
Peptide H-TL^SDYNIQK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.SARS-CoV-2 Spike (1196-1205)
The SARS-CoV-2 spike protein is present on the outside of the virus particles and can bind to angiotensin-converting enzyme II (ACE2) present on the host cells. The C-terminal receptor binding domain (RBD) of the spike protein binds to the N-terminal peptidase M2 domain of ACE2. This receptor binding results in the internalisation of the virus-receptor complex and is, therefore the mechanism of entry of SARS-CoV-2 into host cells.The spike protein residues SLIDLQELGK (1196-1205) from SARS-CoV-2 have been identified as a T-cell epitope with a predicted HLA restriction. Immune targeting of confirmed epitopes may potentially offer protection against SARS-CoV-2 and help the development of vaccines for long-lasting immunity.Peso molecular:1,114.6 g/molORF65 (131-140) [Murid herpesvirus 4]
Human γHV Epstein-Barr virus (EBV) is host-specific, making it challenging to study. Evidence suggests EBV infection provides an enhanced immune response against other future heterologous infections. Murid herpesvirus 4 (MuHV-4) in mice can be used as a model to help understand herpesviruses. The peptide provided here (ORF65131-140) has been used in CTL assays to show that MuHV-4 improves the effector CD8+ T cells response against a heterologous virus. MuHV-4 ORF65131-140 epitope can stimulate interleukin production ex vivo and be detected by tetramer staining to MHC. Further work with MuHV-4 ORF65131-140 could be crucial for understanding the reactivity of the human immune system to other viruses after infection with γHV Epstein-Barr virus (EBV).Peso molecular:989.5 g/molApolipoprotein E4 (94 - 108)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,730.9 g/molHistone H4 (1-21)
Histone 4 (H4) is one of the four core histones (H2A, H2B, H3 and H4) which are essential for compacting eukaryotic DNA into the nucleosome. Due to the high lysine and arginine content, histones have a net positive charge and therefore electrostatically interact with negatively charged DNA. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Like other core histones, H4 has a globular domain and a flexible N-terminal domain, the histone tail, which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination.Gene transcriptional activation or inactivation is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes. Both processes function to alter the positioning of the nucleosome, allowing the DNA within to be either accessible to the transcription machinery or inaccessible. H4's lysine rich tail plays a role in the higher order chromatin folding.Peso molecular:2,090.2 g/molH-SPKMVQGSGCFGR^KMDRISSSSGLGCK^VLRRH-OH
Peptide H-SPKMVQGSGCFGR^KMDRISSSSGLGCK^VLRRH-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Proto-oncogene PIM1 (191-199)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolCyclo(CLLFVY)
Cyclo(CLLFVY) is a cyclic peptide which binds to the PAS-B domain of HIF-1alpha, thus inhibiting HIF-1 dimerisation and HIF-1 mediated hypoxia signalling.Peso molecular:738.4 g/molSIVmac239 - 36
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,637.9 g/molH-GPSVFPLAPSSR^-OH
Peptide H-GPSVFPLAPSSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Biotin TAT (48-60)
Biotin TAT (48-60) is a cell penetrating cationic peptide derived from the N-terminus of the Tat protein, which is a trans-activator of the transcription protein present in the human immunodeficiency virus (HIV). The 48-60 region of the TAT peptide is an arginine-rich bascic domain which as a whole has three domains that function to aid HIV through transactivation, DNA binding and nuclear transport. As a cell penetrating peptide (CPP) TAT aids in the cellular uptake of molecules and hence serves a valuable purpose in transduction methods. This property has been demonstrated through its ability of allowing toxins such as the neurotoxin Botulinum neurotoxin Type A, produced by the Clostridium botulinum type A bacteria to penetrate the skin barrier non-invasively.This peptide has a covalently bonded N-terminal Biotin tag that can be used for detection and purification and contains an N-terminal aminohexanoic acid spacer (Ahx).Peso molecular:2,057.2 g/molH-ALQVVR^-OH
Peptide H-ALQVVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Histone H3 (1-20) K4Me3, pS10-GG-[Lys(5-FAM)]
Histone 3 (H3) is one of the four core histones (H2A, H2B, H3 and H4) fundamental in compacting eukaryotic DNA into the nucleosome. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Similar to the other core histone, H3 has a globular domain and a flexible N-terminal domain, 'histone tail' which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination. The transcriptional activation or silencing of the chromatin is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes which target histone proteins. Both processes function to alter the positioning of the nucleosome, allowing the DNA it to be either available or inaccessible to the transcription machinery.The lysine at position 4 of this peptide has been tri-methylated and it is implicated in studies that this modification may remodel the chromatin so that it is more accessible to transcription factors, which may ultimately increase the level of gene expression. Moreover, the serine at position 10 has been phosphorylated, and studies have suggested that this may induce chromatin condensation, and subsequently repress transcription and gene expression.Histone H3 (1-20) K4Me3, pS10-GG-[Lys(5-FAM)] has a C-terminal GKK linker labelled with 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag.
Peso molecular:2,904.5 g/molH-SNLELLR^-OH
Peptide H-SNLELLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Myr-KFARLWTEIPTAIT-OH
Peptide Myr-KFARLWTEIPTAIT-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-KLVVVGAGGV^-OH
Peptide H-KLVVVGAGGV^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-VVFGAR^-OH
Peptide H-VVFGAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-GGLNDIFEAQKIEWHED-NH2
Peptide Ac-GGLNDIFEAQKIEWHED-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
![ORF65 (131-140) [Murid herpesvirus 4]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FCRB1001226.webp&w=3840&q=75)
![Histone H3 (1-20) K4Me3, pS10-GG-[Lys(5-FAM)]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FCRB1101264.webp&w=3840&q=75)
