Peptídeos

Suc-Ala-Pro-Ala-AMC is a synthetic peptide that is used as a research tool in pharmacology, cell biology, and other life science fields. This peptide is an activator of ion channels, which are proteins that allow the flow of ions across cell membranes. Suc-Ala-Pro-Ala-AMC binds to ligand receptors on the surface of cells and activates them by opening the channel. The high purity of this product makes it suitable for use in research applications where specific binding is required.

lipophilic peptide

substitution 1.0-1.6 meq/g; swelling (1g swells in 3ml DMF for 24hr).

Angiotensin I (Human) is a peptide that functions as a hormone. It is the major regulator of blood pressure and plays an important role in the regulation of fluid balance, electrolyte balance, and heart rate. Angiotensin I (Human) is a receptor ligand that binds to cell surface receptors which are coupled to G proteins. It has been used extensively as a research tool for studying protein interactions and ion channels.

Boc-Arg-Val-Arg-Arg-AMC is a new type of peptidomimetic ligand that can be used as an inhibitor for ion channels. It has been shown to inhibit the activity of a number of ion channel types, including sodium and calcium channels. Boc-Arg-Val-Arg-Arg-AMC also binds to the receptor site of acetylcholine in muscle cells. This is an important pharmacological tool for research on ion channels, receptors, and peptide interactions.

Anti-false positive reagent for rapid test

Applications N-[1-(Cyano-2-ethoxy-2-oxoethylideneaminooxy)dimethylamino(morpholino)uronium Hexafluorophosphate is used as an efficient coupling agent in phosphonamidation reactions; used as coupling reagent in the synthesis of solid phase peptide
References Fredriksen, K., et al.: Eur. J. Org. Chem., 3, 474 (2016); Achyuthan, K., et al.: J. Pept. Sci., 21, 751 (2015);

Applications Caspase-1 Inhibitor II is an inhibitor of caspase-1, caspase-4, and caspase-5.

Applications N-tert-Boc-D-alanine is an N-Boc-protected form of D-Alanine (A480995). D-Alanine is an amino acid that is commonly found in bacteria, such as Streptococcus faecalis. It is essential for the biosynthesis of peptidoglycan crosslinking sub-units that are used for bacterial cell walls. D-Alanine is also known to cause cytotoxic oxidative stress in brain tumour cells.
References Ellsworth, B., et al.: Chem. Biol., 3, 37 (1996); Ferrari, E. et al.: Nat. Biotech., 3, 1003 (1985); Stegman, L., et al.: Human Gene Ther., 9, 185 (1998); Wood, W. & Gunsalus, I.: J. Biol. Chem., 190, 403 (1951)

Applications Poly(ethylene Glycol) molecules of an average molecular mass of 30,000. Poly(ethylene Glycol) is used in various applications from industrial chemistry to biological chemistry. Recent research has shown PEG maintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals. In rats, it has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery. It is industrially produced as a lubricating substance for various surfaces to reduce friction. PEG is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.
References Borgens, R. et al.: J. Neurosci. Res., 66, 1179 (2001); Stavisky, R. et al.: Neurosci. Lett., 376, 98 (2005); Nalam, P. et al.: Tribiol. Lett., 37, 541 (2010); Steinmetz, N. et al.: J. Am. Chem. Soc., 131, 17093 (2009); Li, X. et al.: J. Am. Chem. Soc., 133, 11147 (2011); Li, L. et al.: Int. J. Pharm., 447, 192 (2013);

Applications CA-074 methyl ester is a cell-permeable cathepsin B inhibitor.

Applications Fmoc-d-asn(trt)-oh, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Applications Phenylalanine derivative used in enantioselective hydrolysis of amino acid esters. Acts as an inhibitor of gastric acid secretion.
References Tomisaka, K. et al.: Chem. Comm., 1, 133 (2001); Magours, R., et al.: Biochim. Biophys. Acta, Mol. Cell Res., 858, 158 (1985)

Applications 23-Azido-3,6,9,12,15,18,21-Heptaoxatricosan-1-ol is used in the synthesis of heterobifunctionalized oligo(ethylene glycol) linkers for use in drug delivery.
References Goswami, L. et al.: Org. Biomol. Chem., 11, 1116 (2013);

Applications 2-NBDG is a fluorescent glucose uptake indicator, used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry.
References Zou, Chenhui., et al.: J Biochem Biophys Methods., 64, 207 (2005); Yamada, Katsuya., et al.: J. Biol. Chem., 275, 22278 (2000)

Applications L-valyl-L-histidyl-L-leucyl-L-threonyl-L-prolyl-L-glutamic Acid, is used as an analyte for the determination of ionization efficiency of glycated and non-glycated peptides from N-terminal of Hb β-chain by electrospray ionization mass spectrometry.
References Nakanishi, T., et al., J. Chromatogr. B. Biomed. Sci. Appl., 746, 83 (2000)

Applications n-Octyl-oligo-oxyethylene is a detergent for useful solubilization, purification and crystallization of proteins.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Used in the composition of drugs containing Ketoprofen, and Sodium hyaluronate as antiinflammatory agents.
References Bajusz, S., et al.: J. Med. Chem., 33, 1729 (1990), Dahlgren, A., et al.: Bioorg. Med. Chem., 10, 1829 (2002),

Applications Elastatinal is an elastase inhibitor.

Applications Spaglumic Acid is a marker of neuronal integrity and was used in the detection of therapeutic values of antidrepressant treatments.
References Taylor, M.J., et al.: Int. J. Neuropharmacol., 15, 1541 (2012); Shi, D.X., et al.: J. Neurochem., 123, 971 (2012); Sun,W., et al.: Science., 339, 197 (2013);

Applications FMOC-ALA-GLY-OH (cas# 116747-54-7) is a useful research chemical.