Moduladores enzimáticos
Moduladores de enzimas são compostos que podem aumentar ou inibir a atividade de enzimas, regulando assim a taxa de reações bioquímicas. Esses moduladores desempenham um papel crucial no controle de vias metabólicas, sinalização celular e vários processos fisiológicos. Os moduladores de enzimas são amplamente utilizados em pesquisa e desenvolvimento de medicamentos para estudar as funções enzimáticas e desenvolver agentes terapêuticos. Na CymitQuimica, oferecemos uma ampla gama de moduladores de enzimas de alta qualidade para apoiar sua pesquisa em regulação enzimática e descoberta de medicamentos.
Subcategorias de "Moduladores enzimáticos"
Foram encontrados 693 produtos de "Moduladores enzimáticos"
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GSK 1278863
CAS:Produto Controlado<p>Inhibitor of HIF-prolyl hydroxylase isozymes PHD1, PHD2 and PHD3 with Ki in nanomolar range. The compound mimics the binding of N-oxalylglycine, chelates catalytic iron and prevents substrate entry into catalytic site. Inhibition of PHD enzymes leads to stabilization of hypoxia-induced factors HIF1α and HIF2α, followed by the production of erythropoietin (EPO).</p>Fórmula:C19H27N3O6Pureza:(%) Min. 95%Cor e Forma:PowderPeso molecular:393.43 g/molTAS 6417 hydrochloride
CAS:<p>TAS 6417 hydrochloride is a small-molecule inhibitor, which is synthesized via chemical processes in pharmaceutical research. It functions primarily as a potent and selective inhibitor of specific mutant forms of the epidermal growth factor receptor (EGFR). By targeting these EGFR mutations, TAS 6417 hydrochloride disrupts the signaling pathways that are crucial for the proliferation and survival of cancer cells.</p>Fórmula:C23H20N6O·HClPureza:Min. 95%Peso molecular:432.91 g/molRibociclib HCl
CAS:<p>Inhibitor of CDK4/6 serine/threonine kinases; antineoplastic</p>Fórmula:C23H30N8O·HClPureza:Min. 95%Cor e Forma:White To Yellow SolidPeso molecular:471 g/molGSK 360A
CAS:<p>Inhibitor of prolyl 4-hydroxylase PHD</p>Fórmula:C17H17FN2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:348.33 g/molBLU 554
CAS:<p>A potent and selective covalent inhibitor of fibroblast growth factor receptor 4 (FGFR4). This receptor tyrosine kinase activates an oncogenic driver in hepatocellular carcinoma, the fibroblast growth factor 19 (FGF19). The FGFR4 inhibitor is therefore a promising candidate for the treatment of advanced liver cancer.</p>Fórmula:C24H24Cl2N4O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:503.38 g/molSacubitril calcium
CAS:<p>Inhibitor of metalloendopeptidase neprilysin</p>Fórmula:C24H29NO5•Ca0Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:431.53 g/molTipifarnib
CAS:<p>Tipifarnib is a farnesyltransferase inhibitor, which is a synthetic compound designed for experimental cancer treatment. It functions by targeting farnesyltransferase, an enzyme involved in the post-translational modification of proteins through the attachment of a farnesyl group to the protein's cysteine residue. This modification is crucial for the activity of several proteins, including those in the Ras signaling pathway, which is often dysregulated in cancer.</p>Fórmula:C27H22Cl2N4OPureza:Min. 95%Peso molecular:489.4 g/molSGX 523
CAS:<p>Inhibits c-MET tyrosine kinases</p>Fórmula:C18H13N7SPureza:Min. 95%Cor e Forma:SolidPeso molecular:359.09531BYL 719
CAS:<p>A selective inhibitor of PI3Kα. Inhibits cancer cell proliferation by blocking the G0/G1 phase of the cell cycle. Anti-tumor effect of BYL 719 has been demonstrated in models of tumors with PI3KCA mutation and amplification in vivo. BYL 719 also suppresses tumor growth in pre-clinical models of osteosarcoma.</p>Fórmula:C19H22F3N5O2SPureza:Min. 95%Cor e Forma:PowderPeso molecular:441.47 g/molLinsitinib
CAS:<p>Dual IGF-1R and InsR kinase inhibitor; antineoplastic</p>Fórmula:C26H23N5OPureza:Min. 95%Cor e Forma:Off-White To Yellow SolidPeso molecular:421.49 g/molLetrozole - Bio-X ™
CAS:Produto Controlado<p>Letrozole is an aromatase inhibitor drug that is used in the treatment of breast cancer in postmenopausal women. It is a non-steroidal type II inhibitor that blocks the active site and thus blocking the electron transfer chain of CYP19A1. As a result of this, the conversion of androgen to estrogen is inhibited.</p>Fórmula:C17H11N5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:285.3 g/molPD 0325901
CAS:<p>A potent non ATP-competitive inhibitor of MAP/ERK kinase (MEK). Has anti-tumor activity in melanoma and papillary thyroid cancer cells with B-Raf mutations. Enhances generation and survival of induced pluripotent stem cells (iPSCs).</p>Fórmula:C16H14F3IN2O4Pureza:Min. 95%Peso molecular:482.19 g/molTacrolimus monohydrate - Bio-X ™
CAS:<p>Tacrolimus is a calcineurin inhibitor drug that is used for the prevention of rejection after an organ transplant. This drug can also be used in the treatment of severe atopic dermatitis. Tacrolimus’ mechanism of action is not well known however it is understood that this drug inhibits T-lymphocyte activation by binding to an intracellular protein called FKBP-12. This drug also has anti-inflammatory properties.</p>Fórmula:C44H69NO12·H2OPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:822.03 g/molCaspase Modulator I, 1541
CAS:<p>Caspase Modulator I, 1541 is a chemical compound designed to modulate the activity of caspases, a family of cysteine proteases critical in the regulation of apoptosis and inflammation. This product is synthesized through advanced chemical processes to ensure high specificity and potency. Its mode of action involves the selective inhibition and modulation of caspase activity, thereby influencing apoptotic pathways and immune responses.</p>Fórmula:C24H17N3O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:411.41 g/molGSK 626616
CAS:<p>Potent inhibitor of dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) with IC50 value of 0.7 nM. Elevates hemoglobin and platelet levels in anemic mice.</p>Fórmula:C18H10Cl2N4OSPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:401.27 g/mol(S)-Lisinopril - Bio-X ™
CAS:<p>Lisinopril is a drug that belongs to the group of angiotensin converting enzyme (ACE) inhibitors. It is used to treat hypertension, heart failure and myocardial infarction. Lisinopril binds to the active site of the ACE enzyme, preventing it from converting angiotensin I into angiotensin II.</p>Fórmula:C21H31N3O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:405.49 g/molTofacitinib
CAS:<p>JAK3 enzyme inhibitor</p>Fórmula:C16H20N6OPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:312.37 g/molFloctafenine
CAS:<p>Nonsteroidal anti-inflammatory (NSAID)</p>Fórmula:C20H17F3N2O4Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:406.36 g/molLomeguatrib
CAS:<p>Inhibitor and pseudosubstrate of DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT). It is used as a sensitizer for the treatment of advanced solid tumors, including prostate, colorectal and central nervous system malignancies. Lomeguatrib inhibits the repair mechanism of DNA damage induced by alkylating agents such as temozolomide, and therefore potentiates its anti-cancer effects.</p>Fórmula:C10H8BrN5OSPureza:Min. 95%Cor e Forma:SolidPeso molecular:324.96329
