Cyclosporin A - Bio-X ™

CAS: 59865-13-3

Ref. 3D-BC164336

Informação sobre produto

• Nome: Cyclosporin A - Bio-X ™
• Sinónimos: CyclosporineCiclosporinAtopica, Cyclosporina, Cyclosporine, Cyclosporin, Restasis, cyclosporin A, Antibiotic S 7481F1, 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 1: PN: US6686454 SEQID: 1 claimed protein, 7: PN: WO0002548 PAGE: 30 claimed protein, Arpimune ME, Cicloral, Cicloral (antibiotic), Ciclosporin, Cipol N, Consupren, Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl], Debio088, Equoral, Gengraf, Neoplanta, Neoral, Nsc 290193, Ol 27-400, Papilock Mini, Ramihyphin A, Sandimmun, Sandimmune, Sandimmune Neoral, Sang-35, SangCyA, Sdz-Oxl 400, Sigmasporin Microoral, S-Neoral, Zinograf ME, Sandimmun Neoral

Descrição

Cyclosporin A (CsA) is a cyclic undecapeptide that is extracted from the fungus Tolypocladium inflatum. CsA is used as an immunosuppressive drug to prevent rejection of transplanted organs and to treat autoimmune diseases such as rheumatoid arthritis and psoriasis. CsA works by binding to a protein called cyclophilin D, which is a component of the enzyme calcineurin. Calcineurin is an important enzyme involved in the activation of immune cells, and by binding to cyclophilin D, CsA inhibits its activity. This leads to the inhibition of T-cell activation and the suppression of the immune response. Cyclosporin A has has been rpeorted to exhibit some nephrotoxicity, hypertension and also increases the risk of infections and tumors when used in transplantation

Cyclosporin is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 1,202.61 g/mol
• Fórmula: C₆₂H₁₁₁N₁₁O₁₂
• Pureza: Min. 95%
• Cor/forma: White Powder