(S,E)-3-(6-Bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide

CAS: 857064-38-1

Ref. 3D-FB34118

Informação sobre produto

• Nome: (S,E)-3-(6-Bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide
• Sinónimos: WP1066

Descrição

(S,E)-3-(6-Bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide (MBI-23) is a potential antineoplastic agent that has been shown to induce regression of bladder cancer in mice. MBI-23 induces apoptosis by inhibiting the proliferation of cancer cells and inducing differentiation of cancer stem cells. It is also shown to inhibit tumor growth and progression in glioma and prostate cancer models. MBI-23 binds to the KDR receptor subtype, which is activated by organic acids and inhibited by inorganic compounds. This binding leads to constitutive activation of the KDR receptor, thereby inducing apoptosis. The tautomers and stereoisomers of MBI-23 have not been fully elucidated yet.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 356.22 g/mol
• Fórmula: C₁₇H₁₄ON₃Br
• Pureza: Min. 98 Area-%
• Cor/forma: White Powder