ω-Conotoxin GVIA trifluoroacetate salt

CAS: 106375-28-4

Ref. 3D-FC109903

Informação sobre produto

• Nome: ω-Conotoxin GVIA trifluoroacetate salt
• Sinónimos: H-Cys-Lys-Ser-Hyp-Gly-Ser-Ser-Cys-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys-Tyr-NH2 trifluoroacetate s alt (Disulfide bonds between Cys1 and Cys16/Cys8 and Cys19/ Cys15 and Cys26
• Marca: Biosynth
• Descrição: Omega-Conotoxin GVIA is a type of toxin from the venom of the marine snail Conus geographus. It binds to the kappa-opioid receptor, which is found on neurons in the central and peripheral nervous system. This binding inhibits voltage-dependent calcium channels and leads to neuronal death. Omega-Conotoxin GVIA has been shown to inhibit diastolic pressure in rats, as well as glomerular filtration rate (GFR) and kappa-opioid receptors in mice. The inhibition of GFR may be due to its effect on Ca2+ signaling, leading to decreased activity of the Na/K ATPase pump in proximal tubules.

Propriedades químicas

• Peso molecular: 3,037.36 g/mol
• Fórmula: C₁₂₀H₁₈₂N₃₈O₄₃S₆
• Pureza: Min. 95%