Bortezomib

CAS: 179324-69-7

Ref. 3D-FM19000

Informação sobre produto

• Nome: Bortezomib
• Sinónimos: [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-boronic acidRadiciol, B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid, Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-, Boronic acid, [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-, Boronic acid, [3-methyl-1-[[1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-, [S-(R*,S*)]-, Bortezomib for research, Bortizomib, Brotezamide, Dpba, Ldp 341, Mg 341, Mln 341, N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-Nalpha-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide, N-[(1S)-1-(dihydroxyboranyl)-3-methylbutyl]-Nalpha-(pyrazin-2-ylcarbonyl)-D-phenylalaninamide, NSC 681239, PS 341 (pharmaceutical), Ps 314, Ps 341, Radiciol, Velcade, [(1R)-3-Methyl-1-[[(2S)-1-Oxo-3-Phenyl-2-[(Pyrazinylcarbonyl)Amino]Propyl]Amino]Butyl]-Boronic Acid

Descrição

Selective and reversible inhibitor of the multicatalytic 26S proteasome. The inhibition of protein breakdown affects several metabolic pathways and leads to cell death. The compound is effective in treating multiple myeloma because it prevents the binding of myeloma cells to bone marrow stroma and inhibits osteoclast differentiation.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 384.24 g/mol
• Fórmula: C₁₉H₂₅BN₄O₄
• Pureza: Min. 95%
• Cor/forma: White Powder
• InChI: InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1
• Chave InChI: InChIKey=GXJABQQUPOEUTA-RDJZCZTQSA-N
• SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O