Informação sobre produto
AZ 12216052 is a selective allosteric modulator of the NMDA receptor that has shown antidepressant-like activity in whole-cell voltage-clamp studies. AZ 12216052 inhibits glutamate release by binding to and blocking the NMDA receptor, which prevents calcium influx into the postsynaptic neuron. It also has been found to have neuroprotective effects in an animal model of Huntington’s disease. The drug binds to NMDA receptors at a site different from that of ketamine, an anaesthetic and analgesic used as a rapid-onset antidepressant and pain reliever.
AZ 12216052 is currently being studied for its potential use as a cancer treatment due to its ability to inhibit tumor growth by reducing glutamate receptor signaling in ganglion cells and suppressing neurotransmission between neurons.
Propriedades químicas
Consulta técnica sobre: 3D-QBC62831 AZ 12216052
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