Gigantol

CAS: 67884-30-4

Ref. TM-TL0008

Informação sobre produto

• Nome: Gigantol
• Sinónimos: Phenol, 5-[2-(3-Hydroxy-5-Methoxyphenyl)Ethyl]-2-Methoxy-
• CAS: 67884-30-4

Descrição

Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases, it shows the protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway.Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-κB signaling pathway.Gigantol also shows α-glucosidase inhibitory activity.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 274.31
• Fórmula: C₁₆H₁₈O₄
• Pureza: 99.48%
• Cor/forma: Solid