O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-Phenylcarbamate

CAS: 132489-69-1

Ref. TR-A157250

Informação sobre produto

• Nome: O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-Phenylcarbamate
• Sinónimos: [(Z)-[(3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-ylidene]amino] N-phenylcarbamate, <span class="text-smallcaps">D</span>-Gluconimidic acid, 2-(acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-, δ-lactone, (1Z)-, N-Acetylglucosaminono-1,5-Lactoneo-(Phenylcarbamoyl)Oxime, N-[(2Z,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(phenylcarbamoyl)oxy]imino}tetrahydro-2H-pyran-3-yl]acetamide (non-preferred name), O-(2-Acetamido-2-deoxy-D-glucopyranosylidenamino) N-phenylcarbamate, acetamidodeoxy-D-glucopyranosylideneamino phenylcarbamate
• CAS: 132489-69-1

Descrição

Stability Moisture and Temperature Sensitive
Applications An inhibitor of O-GlcNAcase, hexosaminidase A, and hexosaminidase B.
References Baji, H., et al,: Eur. J. Med. Chem., 30, 617 (1995), Vaaje-Kolstad, G., et al.: J. Biol. Chem., 279, 3612 (2004), Perreira, M., et al.: Bioorg. Med. Chem., 14, 837 (2006).

• Marca: TRC

Propriedades químicas

• Peso molecular: 353.33
• Fórmula: C₁₅H₁₉N₃O₇
• Cor/forma: Neat
• InChI: InChI=1S/C15H19N3O7/c1-8(20)16-11-13(22)12(21)10(7-19)24-14(11)18-25-15(23)17-9-5-3-2-4-6-9/h2-6,10-13,19,21-22H,7H2,1H3,(H,16,20)(H,17,23)/b18-14-/t10-,11-,12-,13-/m1/s1
• Chave InChI: InChIKey=PBLNJFVQMUMOJY-JXZOILRNSA-N
• SMILES: CC(=O)N[C@H]1/C(=N/OC(=O)Nc2ccccc2)O[C@H](CO)[C@@H](O)[C@@H]1O