(S)-2-Chloro-1-(3,4-difluorophenyl)ethanol

CAS: 1006376-60-8

Ref. TR-C365268

Informação sobre produto

• Nome: (S)-2-Chloro-1-(3,4-difluorophenyl)ethanol
• Sinónimos: (αS)-α-(Chloromethyl)-3,4-difluorobenzenemethanol
• Marca: TRC
• Descrição: Applications (S)-2-Chloro-1-(3,4-difluorophenyl)ethanol is a building block used in organic synthesis including bein an intermediate in the synthesis of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),

Propriedades químicas

• Peso molecular: 192.59
• Fórmula: C₈H₇ClF₂O
• Cor/forma: Neat
• InChI: InChI=1S/C8H7ClF2O/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,12H,4H2/t8-/m1/s1
• Chave InChI: InChIKey=UGQQAJOWXNCOPY-BKPFTMJTSA-N
• SMILES: ClC1=C(Cl)[C@]2(Cl)[C@@H]3CC[C@H]4[C@@H](CC[C@@H]3[C@@]1(Cl)C2(Cl)Cl)[C@@]1(Cl)C(Cl)=C(Cl)[C@]4(Cl)C1(Cl)Cl