3-Hydroxy-2-naphthoic Acid-d6

CAS: 92-70-6

Ref. TR-H951079

Informação sobre produto

• Nome: 3-Hydroxy-2-naphthoic Acid-d6
• Sinónimos: 1,4,5,6,7,8-hexadeuterio-3-hydroxynaphthalene-2-carboxylic acid, 2,3-Bon Acid, 2-Hydroxy-3-Naphthalene Carboxylic acid, 2-Hydroxy-3-carboxynaphthalene, 2-Hydroxy-3-naphthalenecarboxylic acid, 2-Hydroxy-3-naphthoic acid, 2-Hydroxyl-3-naphthoic acid, 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-Naphthoic acid, 3-hydroxy-, 2-Naphthol-3-carboxylic acid, 3-Carboxy-2-naphthol, 3-Hydroxy-2-Naphthalene Carboxylic acid, 3-Hydroxy-2-Naphthoesaeure, 3-Hydroxy-2-Naphthslene Carboxylic acid, 3-Hydroxy-2-naphthalenecarboxylic acid, 3-Hydroxy-2-naphthoesaure, 3-Hydroxy-β-naphthoic acid, 3-Hydroxynaphthalene-2-Carboxylate, 3-Naphthol-2-carboxylic acid, Acide 3-hydroxy-2-naphtoique, Acido 3-Hidroxi-2-Naftoico, B-Oxynaphthoic Acid, BON, Beta-Oxynaphthoic Acid, Bon Acid, Bona, Developer BON, H 0281, Miketazol Developer ONS, Naphthalene-2-Carboxylic Acid, 3-Hydroxy-, Naphthol B.O.N., Nsc 3719, Refined Bon Acid, Tci-B 3229, β-Hydroxy-3-naphthoic acid, β-Hydroxynaphthoic acid

Descrição

Applications 3-Hydroxy-2-naphthoic Acid-d6 is an intermediate used in the synthesis of Pamoic Acid-d10 (P173502), which is a labelled Pamoic Acid. Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases. Enzyme replacement therapy in pancreatic enzyme deficiency.
References Fonge H., et al.: Bioconjugate Chem., 18, 1924 (2007), Mayr, G.W., et al.: J. Biol. Chem., 282, 35424 (2007); Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010); Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009);

• Marca: TRC

Propriedades químicas

• Peso molecular: 194.216
• Fórmula: C₁₁D₆H₂O₃
• Cor/forma: Neat
• InChI: InChI=1S/C11H8O3/c12-10-6-8-4-2-1-3-7(8)5-9(10)11(13)14/h1-6,12H,(H,13,14)/i1D,2D,3D,4D,5D,6D
• Chave InChI: InChIKey=ALKYHXVLJMQRLQ-MZWXYZOWSA-N
• SMILES: [2H]c1c([2H])c([2H])c2c([2H])c(C(=O)O)c(O)c([2H])c2c1[2H]