2,3,4,6-Tetrakis-O-trimethylsilyl-L-gluconolactone

CAS: 32384-65-9

Ref. TR-T279543

Informação sobre produto

• Nome: 2,3,4,6-Tetrakis-O-trimethylsilyl-L-gluconolactone
• Sinónimos: (3S,4R,5S,6S)-3,4,5-Tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one, (3R,4S,5R,6R)-3,4,5-Tri[(trimethylsilyl)oxy]-6-[[(trimethylsilyl)oxy]methyl]tetrahydro-2H-pyran-2-one, (3R,4S,5R,6R)-3,4,5-Tris((Trimethylsilyl)Oxy)-6-(((Trimethylsilyl)Oxy)Methyl)Tetrahydropyran-2-One, (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)-tetrahydropyran-2-one, (3R,4s,5r,6r)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)tetrahydro-2h-pyran-2-one, 2,3,4,6-Tetra-O-(trimethylsilyl)-<span class="text-smallcaps">D</span>-glucono-1,5-lactone, 2,3,4,6-Tetrakis-O-triMethylsilyl-D-gluconolactoe, 2,3,4,6-Tetrakis-O-trimethylsilyl-<span class="text-smallcaps">D</span>-gluconolactone, <span class="text-smallcaps">D</span>-Gluconic acid, 2,3,4,6-tetrakis-O-(trimethylsilyl)-, δ-lactone, D-2,3,4,6-Tetrakis-O-(Trimethylsilyl)-Gluconic Acid Delta-Lactone, Gluconic acid, 2,3,4,6-tetrakis-O-(trimethylsilyl)-, δ-lactone, <span class="text-smallcaps">D</span>-

Descrição

Stability Moisture Sensitive
Applications 2,3,4,6-Tetrakis-O-trimethylsilyl-L-gluconolactone is an intermediate in synthesizing Ent-α-C Dapagliflozin (D185365), is an enantiomer of Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.
References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)

• Marca: TRC

Propriedades químicas

• Peso molecular: 466.865
• Fórmula: C₁₈H₄₂O₆Si₄
• Cor/forma: Neat
• InChI: InChI=1S/C18H42O6Si4/c1-25(2,3)20-13-14-15(22-26(4,5)6)16(23-27(7,8)9)17(18(19)21-14)24-28(10,11)12/h14-17H,13H2,1-12H3/t14-,15-,16+,17-/m0/s1
• Chave InChI: InChIKey=VNGTZLYNGGLPIZ-NXOAAHMSSA-N
• SMILES: C[Si](C)(C)OC[C@@H]1OC(=O)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C