CAS 100-07-2

4-Methoxybenzoyl chloride

Description:

4-Methoxybenzoyl chloride, with the CAS number 100-07-2, is an aromatic acyl chloride characterized by the presence of a methoxy group (-OCH₃) para to the carbonyl chloride functional group (-COCl) on a benzene ring. This compound is typically a colorless to pale yellow liquid with a pungent odor, indicative of its reactivity. It is soluble in organic solvents such as dichloromethane and ether but is generally insoluble in water due to its hydrophobic aromatic structure. 4-Methoxybenzoyl chloride is known for its role as an acylating agent in organic synthesis, particularly in the preparation of esters and amides. It is sensitive to moisture and can hydrolyze to form 4-methoxybenzoic acid, making it necessary to handle it under anhydrous conditions. Safety precautions are essential when working with this compound, as it can cause severe irritation to the skin, eyes, and respiratory system. Proper storage in a cool, dry place, away from moisture and incompatible substances, is crucial to maintain its stability and reactivity.

Formula: C₈H₇ClO₂

InChI: InChI=1S/C8H7ClO2/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3

InChI key: InChIKey=MXMOTZIXVICDSD-UHFFFAOYSA-N

SMILES: C(Cl)(=O)C1=CC=C(OC)C=C1

Synonyms:

• 4-Anisoyl chloride
• 4-Methoxybenzoic acid chloride
• 4-Methoxybenzoyl chloride
• 4-Methoxychlorobenzoyl
• 4-Methoxyphenylchloroform
• Anisoyl Chloride
• Anisoylchlorid
• Chlorure d'anisoyle
• Cloruro De Anisoilo
• Nsc 86125
• Para-anisoyl chloride
• p-Anisoyl chloride
• p-Methoxybenzoic acid chloride
• p-Methoxybenzoyl chloride

4-Methoxybenzoyl Chloride

CAS: 100-07-2

Formula: C₈H₇ClO₂

Purity: >99.0%(GC)

Color and Shape: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Molecular weight: 170.59

Ref: 3B-M0721

4-Methoxybenzoyl chloride, 97%

CAS: 100-07-2

4-Methoxybenzoyl chloride is used in the synthesis of stilbene and dihydrostilbene derivatives as potential anti-cancer agents. It is also used in the synthesis of coumarin dimers with potential HIV-1 activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar prod

Formula: C₈H₇ClO₂

Purity: 97%

Color and Shape: Colorless to white to yellow, Fused solid or clear liquid as melt

Molecular weight: 170.59

Ref: 02-L13120

p-Anisoyl chloride

CAS: 100-07-2

p-Anisoyl chloride

Formula: C₈H₇ClO₂

Purity: By gc: 99.9% (Typical Value in Batch COA)

Color and Shape: white crystalline solid

Molecular weight: 170.59g/mol

Ref: 54-OR315757

4-Methoxybenzoyl Chloride

Controlled Product

CAS: 100-07-2

Applications 4-Methoxybenzoyl Chloride is used in the synthesis of stilbene and dihydrostilbene derivatives as potential anti-cancer agents. It is also used in the synthesis of coumarin dimers with potential HIV-1 activity.
References Cushman, M., et al.: J. Med. Chem., 34, 2579 (1991); Mao, P., et al.: Chem. Pharm. Bull. 50, 1634 (2002);

Formula: C₈H₇ClO₂

Color and Shape: Neat

Molecular weight: 170.59

Ref: TR-M288915