CAS 100-11-8

4-Nitrobenzyl bromide

Description:

4-Nitrobenzyl bromide is an organic compound characterized by its aromatic structure, featuring a nitro group (-NO2) and a bromomethyl group (-CH2Br) attached to a benzene ring. This compound typically appears as a pale yellow to light brown solid and is known for its reactivity, particularly in nucleophilic substitution reactions due to the presence of the bromine atom, which is a good leaving group. The nitro group, being an electron-withdrawing group, enhances the electrophilicity of the benzyl position, making it more susceptible to nucleophilic attack. 4-Nitrobenzyl bromide is often utilized in organic synthesis, particularly in the preparation of various derivatives and as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is important to handle this compound with care, as it may pose health risks, including irritation to the skin and eyes, and should be used in a well-ventilated area with appropriate personal protective equipment.

Formula: C₇H₆BrNO₂

InChI: InChI=1S/C7H6BrNO2/c8-5-6-1-3-7(4-2-6)9(10)11/h1-4H,5H2

InChI key: InChIKey=VOLRSQPSJGXRNJ-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=CC=C(CBr)C=C1

Synonyms:

• 1-(Bromomethyl)-4-nitrobenzene
• 4-(Bromomethyl)nitrobenzene
• 4-Nitrobenzyl bromide
• 4-Nitrophenylmethyl bromide
• Benzyl Bromide, 4-Nitro-
• Nsc 4609
• Toluene, α-bromo-p-nitro-
• p-(Bromomethyl)nitrobenzene
• p-Nitro-α-bromotoluene
• p-Nitrobenzyl bromide
• Α-Bromo-4-Nitrotoluene
• Α-Bromo-4-Nitrotolueno
• α-Brom-4-nitrotoluol
• α-Bromo-p-nitrotoluene
• 4-Nitrobenzyl bromide,(a-Bromo-4-nitrotoluene)
• Pratropium bormide
• 4-Nitrobenzyl bromide/a-Bromo-4-Nitrotoluene
• Benzene, 1-(bromomethyl)-4-nitro-
• alpha-Bromoparanitrotoluene
• 3,5-Dinitrobenzyl chloride

4-Nitrobenzyl Bromide

CAS: 100-11-8

Formula: C₇H₆BrNO₂

Purity: >98.0%(GC)(T)

Color and Shape: Very Pale Yellow - Pale Reddish Yellow Solid

Molecular weight: 216.03

Ref: 3B-N0181

4-Nitrobenzyl bromide, 97+%

CAS: 100-11-8

4-Nitrobenzyl bromide is used in the synthesis of di and tri-substituted azoles. It is also used in the preparation of N6-Benzyladenosine-5’-uronamides as selective A3 adenosine agonists. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some doc

Formula: C₇H₆BrNO₂

Purity: 97+%

Color and Shape: White to cream or pale yellow, Crystalline powder

Molecular weight: 216.03

Ref: 02-A15236

4-Nitrobenzyl bromide

CAS: 100-11-8

4-Nitrobenzyl bromide

Formula: C₇H₆BrNO₂

Purity: 98%

Color and Shape: white to off white solid

Molecular weight: 216.03g/mol

Ref: 54-OR28642

4-Nitrobenzyl bromide

CAS: 100-11-8

BR1095 - 4-Nitrobenzyl bromide

Formula: C₇H₆BrNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 216.034

Ref: 10-BR1095

4-Nitrobenzyl bromide

CAS: 100-11-8

Formula: C₇H₆BrNO₂

Purity: ≥ 98.5%

Color and Shape: Off-white to light yellow powder

Molecular weight: 216.04

Ref: 7W-GK9069

4-Nitrobenzyl Bromide

Controlled Product

CAS: 100-11-8

Applications 4-Nitrobenzyl Bromide is used in the synthesis of di and tri-substituted azoles. Also used in the preparation of N6-Benzyladenosine-5’-uronamides as selective A3 adenosine agonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gallo-Rodriguez, C. et al.: J. Med. Chem., 37, 636 (1994); Appukkuttan, P. et al.: Org. Lett., 6, 23 (4223);

Formula: C₇H₆BrNO₂

Color and Shape: Neat

Molecular weight: 216.03

Ref: TR-N493640

4-Nitrobenzyl bromide

CAS: 100-11-8

4-Nitrobenzyl bromide is a reactive compound that reacts with the hydroxyl group of phenols to form 4-nitrophenols. It has been shown to react with congestive heart failure (CHF) patients' sera and bind to receptors on the surface of red blood cells, thereby inhibiting their ability to carry oxygen. The reaction mechanism for this process is unclear, but it is thought that it may involve a nucleophilic attack on the double bond in the phenol by a hydroxyl radical. This chemical can also be used as an analytical method for determining organic acids in natural compounds. Monoclonal antibodies are used for this purpose because they are specific for certain organic acids and thus will only react with them.

Formula: C₇H₆BrNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 216.03 g/mol

Ref: 3D-FN38852

p-Nitrobenzyl Bromide (PNBBR) pure, 99%

CAS: 100-11-8

Formula: C₇H₆O₂NBr

Purity: min. 99%

Color and Shape: White to Off-white Pale yellow to Pale brown, Crystalline powder, Clear, Pale yellow to Yellow

Molecular weight: 216.04

Ref: SR-12790