CAS 100020-57-3

METHYLTHIO-ATP, 2-

Description:

Methylthio-ATP, 2- (CAS 100020-57-3) is a nucleotide analog that serves as a potent and selective agonist for purinergic receptors, particularly P2Y receptors. This compound is characterized by the presence of a methylthio group, which enhances its biological activity compared to adenosine triphosphate (ATP). Methylthio-ATP is typically used in biochemical research to study cellular signaling pathways, particularly those involving ATP and its derivatives. Its structural modifications allow it to interact with various enzymes and receptors, making it a valuable tool in pharmacology and cell biology. The compound is soluble in aqueous solutions, which facilitates its use in in vitro experiments. Additionally, it exhibits a range of physiological effects, including modulation of neurotransmitter release and influence on vascular smooth muscle contraction. As with many nucleotide analogs, careful handling and storage are essential to maintain its stability and efficacy in experimental applications.

Formula: C₁₁H₁₄N₅Na₄O₁₃P₃S

Synonyms:

• METHYLTHIO-ATP, 2-

2-Methylthioadenosine triphosphate tetrasodium salt

CAS: 100020-57-3

2-Methylthioadenosine triphosphate tetrasodium salt is a purinergic receptor antagonist that inhibits the activation of adenosine receptors. It has been shown to block the release of cytosolic calcium, which may be due to its ability to inhibit phospholipase A2 and polymerase chain reaction. 2-Methylthioadenosine triphosphate tetrasodium salt is used in biological samples such as human plasma and serum, as well as in model systems, where it shows anti-inflammatory and anti-apoptotic effects. 2-Methylthioadenosine triphosphate tetrasodium salt also inhibits the production of adenosine by interfering with the activity of adenylate kinase. This drug can be used for the treatment of diseases such as asthma or chronic obstructive pulmonary disease (COPD).

Formula: C₁₁H₁₄N₅Na₄O₁₃P₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 641.2 g/mol

Ref: 3D-AEA02057

2-Methylthio-ATP tetrasodium

CAS: 100020-57-3

2-Methylthio-ATP tetrasodium is a non-specific P2 receptor agonist, which can activate P2X2 and P2Y1 receptors and inhibiti ADP-induced platelet aggregation.

Formula: C₁₁H₁₄N₅Na₄O₁₃P₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 641.2

Ref: TM-T22496