CAS 100040-31-1: gastric inhibitory polypeptide human
CAS 100040-31-1: gastric inhibitory polypeptide human
Description:Gastric inhibitory polypeptide (GIP), also known as glucose-dependent insulinotropic polypeptide, is a peptide hormone produced in the K cells of the duodenum and jejunum in the gastrointestinal tract. It plays a crucial role in glucose metabolism by stimulating insulin secretion from the pancreas in response to food intake, particularly in the presence of glucose and fatty acids. GIP also inhibits gastric acid secretion and gastric motility, hence its name. The substance is composed of 42 amino acids and is part of the incretin family, which are hormones that enhance insulin release. GIP's action is mediated through specific receptors on pancreatic beta cells, and it has implications in metabolic disorders such as type 2 diabetes. The CAS number 100040-31-1 uniquely identifies this peptide, facilitating its study and application in research and clinical settings. Overall, GIP is significant in understanding the interplay between the digestive system and metabolic regulation.
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