CAS 1000578-26-6

(2S)-1,2,3,4-Tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-naphthalenamine

Description:

The chemical substance known as (2S)-1,2,3,4-Tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-naphthalenamine, with the CAS number 1000578-26-6, is a complex organic compound characterized by its multi-ring structure and specific stereochemistry. It features a tetrahydro-naphthalene core, which contributes to its hydrophobic properties, and a dimethylamino group that enhances its basicity and potential for interaction with biological targets. The presence of a pyrazole ring, particularly with three methyl substituents, suggests potential for diverse reactivity and biological activity, possibly influencing its pharmacological profile. This compound may exhibit properties such as solubility in organic solvents and moderate stability under standard conditions. Its stereochemistry, indicated by the (2S) designation, suggests that it may have specific interactions in biological systems, potentially affecting its efficacy and safety in applications. Overall, this compound's unique structural features make it of interest in medicinal chemistry and drug development.

Formula: C₁₈H₂₅N₃

InChI: InChI=1S/C18H25N3/c1-12-18(13(2)21(5)19-12)17-8-6-7-14-11-15(20(3)4)9-10-16(14)17/h6-8,15H,9-11H2,1-5H3/t15-/m0/s1

InChI key: InChIKey=BTTOYOKCLDAHHO-HNNXBMFYSA-N

SMILES: CC1=C(C2=C3C(C[C@@H](N(C)C)CC3)=CC=C2)C(C)=NN1C

Synonyms:

• 2-Naphthalenamine, 1,2,3,4-tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-, (2S)-
• AS 19
• (2S)-1,2,3,4-Tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-naphthalenamine
• (2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN

AS 19

CAS: 1000578-26-6

AS 19 is a potent antimicrobial agent that belongs to the class of 5-hydroxytryptamine receptor agonists. It has been shown to inhibit the growth of bacterial strains in vitro, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. AS 19 is also active against Escherichia coli, Salmonella enterica serovar Typhimurium, Mycobacterium tuberculosis and Mycobacterium avium complex. This drug has been shown to be a potent inhibitor of neuronal death in rats. The mechanism of action is not yet clear; however, it may be due to the inhibition of 5-ht7 receptors on neurons or an anti-inflammatory effect. AS 19 inhibits locomotor activity at low doses and induces locomotor activity at high doses in mice.

Formula: C₁₈H₂₅N₃

Purity: Min. 95%

Molecular weight: 283.41 g/mol

Ref: 3D-AQB57826

AS19

CAS: 1000578-26-6

AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM).

Formula: C₁₈H₂₅N₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 283.41

Ref: TM-T10380