CAS 10015-88-0

1-Palmitoyl-2-oleoylphosphatidylethanolamine

Description:

1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a phospholipid that plays a crucial role in cellular membranes, particularly in the formation of lipid bilayers. It is characterized by its amphiphilic nature, possessing both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions, which allows it to form stable structures in aqueous environments. The molecule consists of a glycerol backbone, two fatty acid chains—one saturated (palmitoyl) and one unsaturated (oleoyl)—and a phosphatidylethanolamine head group. This unique structure contributes to its fluidity and flexibility within membranes, making it essential for various biological processes, including membrane fusion and cell signaling. POPE is often utilized in biophysical studies and drug delivery systems due to its biocompatibility and ability to encapsulate hydrophobic compounds. Additionally, it is involved in the formation of liposomes and other lipid-based nanocarriers, which are important in pharmaceutical applications. Overall, POPE is a significant component in the study of membrane dynamics and cellular interactions.

Formula: C₃₉H₇₆NO₈P

InChI: InChI=1/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-

InChI key: InChIKey=FHQVHHIBKUMWTI-ZCXUNETKNA-N

SMILES: C(OC(CCCCCCC/C=C\CCCCCCCC)=O)(COC(CCCCCCCCCCCCCCC)=O)COP(OCCN)(=O)O

Synonyms:

• Olein, 1-palmito-2-, dihydrogen phosphate, 2-aminoethyl ester
• Ethanol, 2-amino-, dihydrogen phosphate (ester), monoester with 1-palmito-2-olein
• Olein, 1-palmito-2-, 2-aminoethyl hydrogen phosphate
• 9-Octadecenoic acid (Z)-, 1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester
• 9-Octadecenoic acid (9Z)-, 1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester

1-palmitoyl-2-oleoylphosphatidylethanolamine

CAS: 10015-88-0

Formula: C₃₉H₇₆NO₈P

Purity: 98%

Molecular weight: 717.9964

Ref: IN-DA009R5S

1-Palmitoyl-2-oleoylphosphatidylethanolamine

CAS: 10015-88-0

1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a synthetic phospholipid belonging to the PE class. It can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH. 1-Palmitoyl-2-oleoylphosphatidylethanolamine is used in drug delivery research.

Formula: C₃₉H₇₆NO₈P

Molecular weight: 718

Ref: TM-TCL-00111