CAS 10016-20-3

α-Cyclodextrin

Description:

α-Cyclodextrin is a cyclic oligosaccharide composed of six glucose units linked by α-1,4-glycosidic bonds, forming a toroidal structure. It is a white, crystalline powder that is soluble in water, with a solubility that increases with temperature. This compound is known for its ability to form inclusion complexes with various hydrophobic molecules, enhancing their solubility and stability, which makes it valuable in pharmaceuticals, food, and cosmetic applications. α-Cyclodextrin has a relatively low toxicity profile and is generally recognized as safe (GRAS) for consumption. Its unique structure allows it to encapsulate guest molecules within its hydrophobic cavity, facilitating controlled release and improved bioavailability. Additionally, α-Cyclodextrin exhibits properties such as biodegradability and the ability to modify the release profiles of active ingredients, making it a versatile excipient in drug formulation. Its applications extend beyond pharmaceuticals to areas like food preservation and flavor enhancement, showcasing its multifunctional nature in various industries.

Formula: C₃₆H₆₀O₃₀

InChI: InChI=1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1

InChI key: InChIKey=HFHDHCJBZVLPGP-RWMJIURBSA-N

SMILES: C(O)[C@@H]1[C@@]2([C@H](O)[C@@H](O)[C@](O1)(O[C@@]3([C@@H](CO)O[C@@]([C@H](O)[C@H]3O)(O[C@@]4([C@@H](CO)O[C@@]([C@H](O)[C@H]4O)(O[C@]5([C@H](O)[C@@H](O)[C@@](O[C@]6([C@H](O)[C@@H](O)[C@@](O[C@]7([C@H](O)[C@@H](O)[C@@](O2)(O[C@@H]7CO)[H])[H])(O[C@@H]6CO)[H])[H])(O[C@@H]5CO)[H])[H])[H])[H])[H])[H])[H])[H]

Synonyms:

• (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.2~3,6~.2~8,11~.2~13,16~.2~18,21~.2~23,26~]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol (non-preferred name)
• (1S,3R,6S,8R,11S,13R,16S,18R,21S,23R,26S,28R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.2~3,6~.2~8,11~.2~13,16~.2~18,21~.2~23,26~]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol (non-preferred name)
• 2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26]dotetracontane, α-cyclodextrin deriv.
• 5,10,15,20,25,30-Hexakis(Hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.2~3,6~.2~8,11~.2~13,16~.2~18,21~.2~23,26~]Dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-Dodecol (Non-Preferred Name)
• Alpha-Cycloamylose
• Alpha-Dextrin
• Cavamax W 6
• Cavamax W 6 Food
• Celdex A 100
• Ciclohexapentilosa
• Cyclohexaamylose
• Cyclohexaamylose hydrate
• Cyclohexadextrin
• Cyclohexapentylose
• Cyclomaltohexaose
• Cyclomaltohexose
• Dexipar α-100
• Dextrin, α-cyclo
• Dexy Pearl α-100
• Isoeleat K 50
• Nsc 269470
• Ringdex A
• Stereoisomer of 5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol
• Stereoisomer of 5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol
• alpha-Cyclodextrin
• Α-100
• α-Cycloamylose
• α-Cyclodextrin
• α-Dextrin
• α-Schardinger dextrin

α-Cyclodextrin

CAS: 10016-20-3

Formula: C₃₆H₆₀O₃₀

Purity: >98.0%(HPLC)

Color and Shape: White powder to crystal

Molecular weight: 972.85

Ref: 3B-C0776

α-Cyclodextrin, 97+%

CAS: 10016-20-3

Useful for selective precipitation of enantiomeric, positional or structural isomers

Formula: C₃₆H₆₀O₃₀

Purity: 97+%

Color and Shape: White to pale cream, Crystalline powder

Molecular weight: 972.85

Ref: 02-J60687

ALFADEX CRS

CAS: 10016-20-3

ALFADEX CRS

Formula: C₃₆H₆₀O₃₀

Color and Shape: Amorphous. White. Whitish. Crystalline Powder. Powder.

Molecular weight: 972.8436

Ref: 41-A1225000

α Cyclodextrin

CAS: 10016-20-3

Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose; sugar ethers and sugar esters, and their salts, nesoi

Formula: C₃₆H₆₀O₃₀

Color and Shape: White Off-White Crystalline Powder Amorphous Powder

Molecular weight: 972.31694

Ref: 45-1154558

a-Cyclodextrin

CAS: 10016-20-3

Formula: C₃₆H₆₀O₃₀

Purity: 97%

Color and Shape: Solid

Molecular weight: 972.8436

Ref: IN-DA00H969

α-Cyclodextrin

CAS: 10016-20-3

α-Cyclodextrin

Formula: C₃₆H₆₀O₃₀

Purity: By hplc: coforms witrh reference (Typical Value in Batch COA)

Color and Shape: white or almost white powder

Molecular weight: 972.84g/mol

Ref: 54-BIB6038

Sugammadex Impurity 62 (α-Cyclodextrin)

CAS: 10016-20-3

Formula: C₃₆H₆₀O₃₀

Color and Shape: White To Off-White Solid

Molecular weight: 972.85

Ref: 4Z-S-082005

α-Cyclodextrin, Ph. Eur. grade

CAS: 10016-20-3

Formula: C₃₆H₆₀O₃₀·xH₂O

Purity: (dried basis) 98.0 - 101.0 %

Color and Shape: White or almost white, amorphous or crystalline powder

Molecular weight: 972.86

Ref: 7W-GP9262

α-Cyclodextrin

CAS: 10016-20-3

Formula: C₃₆H₆₀O₃₀·xH₂O

Purity: ≥ 98%

Color and Shape: White powder

Molecular weight: 972.86

Ref: 7W-GC6443

α-Cyclodextrin

CAS: 10016-20-3

Formula: C₃₆H₆₀O₃₀

Color and Shape: Neat

Molecular weight: 972.84

Ref: 04-C11821100

α-cyclodextrin

CAS: 10016-20-3

α-cyclodextrin

Formula: C₃₆H₆₀O₃₀

Purity: By hplc: 99.5% (Typical Value in Batch COA)

Color and Shape: Solid

Molecular weight: 972.84g/mol

Ref: 54-BIM1014

α-Cyclodextrin

CAS: 10016-20-3

α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.

Formula: C₃₆H₆₀O₃₀

Purity: 99.79% - 99.9%

Color and Shape: White Solid

Molecular weight: 972.84

Ref: TM-T17303

α-Cyclodextrin

CAS: 10016-20-3

Formula: C₃₆H₆₀O₃₀

Molecular weight: 972.84

Ref: ST-EA-CP-C118001

a-Cyclodextrin

CAS: 10016-20-3

α-Cyclodextrin is a cyclic oligosaccharide with 6 D-glucose residues which are α-1,4-linked. α-cyclodextrin is used in the food industry to encapsulate flavors and fragrances (Kfoury, 2016). α-cyclodextrin is also an effective inhibitor of the upstream inflammatory response induced by cholesterol crystals. Cholesterol crystal-induced complement activation is a critical step in the development of atherosclerosis, thus inhibition of complement with α-cyclodextrin has the potential to be used in the treatment of atherosclerosis (Pilely, 2019).

Formula: C₃₆H₆₀O₃₀

Purity: Min. 90.0 Area-%

Molecular weight: 972.84 g/mol

Ref: 3D-C-9100

a-Cyclodextrin

CAS: 10016-20-3

α-Cyclodextrin is a cyclic oligosaccharide with 6 D-glucose residues which are α-1,4-linked. α-cyclodextrin is used in the food industry to encapsulate flavours and fragrances. α-cyclodextrin is also an effective inhibitor of the upstream inflammatory response induced by cholesterol crystals. Cholesterol crystal-induced complement activation is a critical step in the development of atherosclerosis, thus inhibition of complement with α-cyclodextrin has the potential to be used in the treatment of atherosclerosis.

Formula: C₃₆H₆₀O₃₀

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 972.84 g/mol

Ref: 3D-OC06644

α-Cyclodextrin

CAS: 10016-20-3

Purity: 97%

Color and Shape: Solid

Molecular weight: 972.8460083

Ref: 10-F801970

α-Cyclodextrin Deuterated

Controlled Product

CAS: 10016-20-3

Applications α-Cyclodextrin (C988470) is a 6 member dextrin ring used as an encapsulation agent for bioactive compounds and pharmaceuticals.
References Pinho, E. et al.: Carb. Polym., 101, 121 (2014);

Formula: C₃₆H₄₂D₁₈O₃₀

Color and Shape: Neat

Molecular weight: 990.95

Ref: TR-C988472

α-Cyclodextrin

Controlled Product

CAS: 10016-20-3

Stability Hygroscopic
Applications α-Cyclodextrin is a 6 member dextrin ring used as an encapsulation agent for bioactive compounds and pharmaceuticals.
References Pinho, E. et al.: Carb. Polym., 101, 121 (2014);

Formula: C₃₆H₆₀O₃₀

Color and Shape: Neat

Molecular weight: 972.84

Ref: TR-C988470