CAS 1002304-34-8

7-Methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline

Description:

7-Methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline is a complex organic compound characterized by its unique structural features, which include a quinoline core substituted with a methoxy group and a triazolo-pyridazine moiety. This compound exhibits potential biological activity, making it of interest in medicinal chemistry. The presence of the methoxy groups enhances its lipophilicity, potentially influencing its pharmacokinetic properties. The triazolo and pyridazine rings contribute to its heterocyclic nature, which can affect its reactivity and interaction with biological targets. Additionally, the phenyl group attached to the triazole may provide further steric and electronic effects, impacting the compound's overall stability and activity. As with many such compounds, its solubility, melting point, and other physical properties would depend on the specific conditions and solvent used. Overall, this compound represents a class of heterocyclic compounds that may have applications in drug development and therapeutic research.

Formula: C₂₂H₁₇N₅O₂

InChI: InChI=1S/C22H17N5O2/c1-28-16-7-8-17-19(13-16)23-12-11-20(17)29-14-22-25-24-21-10-9-18(26-27(21)22)15-5-3-2-4-6-15/h2-13H,14H2,1H3

InChI key: InChIKey=HEAIZQNMNCHNFD-UHFFFAOYSA-N

SMILES: COc1ccc2c(c1)nccc2OCc1nnc2ccc(c3ccccc3)nn12

Synonyms:

• Amg 208
• Quinoline, 7-methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]-
• 7-Methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline
• 7-Methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline AMG 208
• AMG208; AMG 208
• AMG-208 USP/EP/BP
• AMG-208, >=98%
• AMG-208;AMG208; AMG 208
• CS-191

Quinoline, 7-methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]-

CAS: 1002304-34-8

Formula: C₂₂H₁₇N₅O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 383.4027

Ref: IN-DA0001AS

AMG-208

CAS: 1002304-34-8

AMG-208

Purity: ≥98%

Molecular weight: 383.4g/mol

Ref: 54-BUP05908

AMG-208

CAS: 1002304-34-8

AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.

Formula: C₂₂H₁₇N₅O₂

Purity: 98.56%

Color and Shape: Solid

Molecular weight: 383.4

Ref: TM-T6260