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CAS 100286-97-3

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Milrinone lactate

Description:
Milrinone lactate is a phosphodiesterase inhibitor primarily used in the management of heart failure. It enhances cardiac output by increasing the levels of cyclic adenosine monophosphate (cAMP) in cardiac and vascular tissues, leading to improved myocardial contractility and vasodilation. This compound is typically administered intravenously in clinical settings, particularly for patients with acute decompensated heart failure. Milrinone lactate is characterized by its relatively rapid onset of action and a short half-life, necessitating continuous infusion for sustained therapeutic effects. The lactate form is a salt that enhances the solubility and stability of the drug in solution. Common side effects may include hypotension, arrhythmias, and headache, which necessitate careful monitoring during administration. As a selective phosphodiesterase type 3 inhibitor, milrinone has a unique mechanism of action compared to other heart failure treatments, making it a valuable option in specific clinical scenarios. Its use, however, is generally reserved for cases where other therapies are insufficient or contraindicated.
Formula:C12H9N3O·xC3H6O3
InChI:InChI=1S/C12H9N3O.C3H6O3/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8;1-2(4)3(5)6/h2-6H,1H3,(H,15,16);2,4H,1H3,(H,5,6)
InChI key:InChIKey=VWUPWEAFIOQCGF-UHFFFAOYSA-N
SMILES:CC1=C(C=C(C#N)C(=O)N1)C=2C=CN=CC2.C(C(O)=O)(C)O
Synonyms:
  • 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile, compd. with 2-hydroxypropionic acid
  • 2-Hydroxypropanoic Acid - 2-Methyl-6-Oxo-1,6-Dihydro-3,4'-Bipyridine-5-Carbonitrile (1:1)
  • Milrinone lactate in 5% dextrose in plastic container
  • Milrinone lactate in dextrose 5% in plastic container
  • Milrinone lactose in 5% dextrose
  • Primacor
  • Primacor (pharmaceutical)
  • Primacor in dextrose 5% in plastic container
  • Propanoic acid, 2-hydroxy-, compd. with 1,6-dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile
  • Propanoic acid, 2-hydroxy-, compd. with 1,6-dihydro-2-methyl-6-oxo[3,4′-bipyridine]-5-carbonitrile (1:?)
  • See more synonyms
Found 6 products.