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CAS 100299-08-9

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Pemirolast potassium

Description:
Pemirolast potassium is a pharmaceutical compound primarily used as an antihistamine and anti-inflammatory agent. It is classified as a mast cell stabilizer, which means it helps prevent the release of histamine and other inflammatory mediators from mast cells, thereby alleviating allergic reactions and conditions such as asthma and allergic conjunctivitis. The substance is typically administered topically or via inhalation, depending on the intended therapeutic application. Pemirolast potassium is known for its relatively low systemic absorption, which minimizes potential side effects. Its chemical structure includes a potassium salt form, enhancing its solubility in aqueous solutions, making it suitable for various formulations. The compound has demonstrated efficacy in clinical settings, particularly in managing allergic responses, and is often well-tolerated by patients. As with any medication, it is essential to consider potential interactions with other drugs and individual patient factors when prescribing or using pemirolast potassium.
Formula:C10H8N6O·K
InChI:InChI=1S/C10H8N6O.K/c1-6-3-2-4-16-9(6)11-5-7(10(16)17)8-12-14-15-13-8;/h2-5H,1H3,(H,12,13,14,15);
InChI key:InChIKey=WXWWEFZPRLRGFL-UHFFFAOYSA-N
SMILES:O=C1N2C(C(C)=CC=C2)=NC=C1C=3NN=NN3.[K]
Synonyms:
  • Pemirolast potassium [USAN:JAN]
  • 4H-Pyrido(1,2-a)pyrimidin-4-one, 9-methyl-3-(1H-tetrazol-5-yl)-, potassium salt
  • UNII-497A17OUUE
  • 9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one, potassium salt
  • TBX (pharmaceutical)
  • potassium 5-(9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)tetrazol-1-ide
  • Pemirolast potassium salt
  • 9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one potassium salt
  • 4H-Pyrido[1,2-a]pyrimidin-4-one, 9-methyl-3-(2H-tetrazol-5-yl)-, potassium salt (1:1)
  • TBX
  • See more synonyms
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