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CAS 100304-60-7

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tyrosyl-arginyl-phenylalanyl-glycinamide

Description:
Tyrosyl-arginyl-phenylalanyl-glycinamide, identified by its CAS number 100304-60-7, is a synthetic peptide that consists of four amino acids: tyrosine, arginine, phenylalanine, and glycine. This compound exhibits characteristics typical of peptides, including the ability to form hydrogen bonds, which can influence its solubility and stability in various environments. The presence of aromatic amino acids like tyrosine and phenylalanine contributes to its potential for engaging in π-π stacking interactions, which can affect its biological activity and interactions with other molecules. Arginine, with its positively charged side chain, can enhance the peptide's solubility in aqueous solutions and facilitate interactions with negatively charged biomolecules. The glycine residue, being the simplest amino acid, provides flexibility to the peptide structure. Overall, this peptide may have applications in biochemistry and pharmacology, particularly in studies related to protein interactions, signaling pathways, or as a potential therapeutic agent, although specific biological activities would depend on its conformation and the context of its use.
Formula:C26H36N8O5
InChI:InChI=1/C26H36N8O5/c27-19(13-17-8-10-18(35)11-9-17)23(37)33-20(7-4-12-31-26(29)30)25(39)34-21(24(38)32-15-22(28)36)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,19-21,35H,4,7,12-15,27H2,(H2,28,36)(H,32,38)(H,33,37)(H,34,39)(H4,29,30,31)/t19-,20-,21-/m0/s1
SMILES:c1ccc(cc1)C[C@@H](C(=NCC(=N)O)O)N=C([C@H](CCCNC(=N)N)N=C([C@H](Cc1ccc(cc1)O)N)O)O
Synonyms:
  • Dermorphin tetrapeptide, tyr-arg-phe-gly-NH2
  • Tyr-arg-phe-gly-NH2
  • Glycinamide, L-tyrosyl-D-arginyl-L-phenylalanyl-
  • L-tyrosyl-N~5~-(diaminomethylidene)-L-ornithyl-L-phenylalanylglycinamide
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