CAS 1003316-10-6

N-[3-[[4-(ChloroMethyl)benzoyl]aMino][1,1'-biphenyl]-4-yl]carbaMic Acid tert-Butyl Ester

Description:

N-[3-[[4-(ChloroMethyl)benzoyl]amino][1,1'-biphenyl]-4-yl]carbamic acid tert-butyl ester, identified by CAS number 1003316-10-6, is a synthetic organic compound characterized by its complex structure, which includes a carbamic acid moiety and a tert-butyl ester group. This compound features a biphenyl backbone, which contributes to its aromatic properties, and a chloroalkyl substituent that may influence its reactivity and biological activity. The presence of the carbamic acid functional group suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, as carbamates are often associated with various biological activities. The tert-butyl ester group enhances the compound's lipophilicity, potentially affecting its solubility and permeability in biological systems. Overall, this compound's unique structural features may provide insights into its reactivity, stability, and potential applications in drug design or as a chemical intermediate in organic synthesis.

Formula: C₂₅H₂₅ClN₂O₃

Synonyms:

• N-[3-[[4-(ChloroMethyl)benzoyl]aMino][1,1'-biphenyl]-4-yl]carbaMic Acid tert-Butyl Ester
• N-[3-[[4-(Chloromethyl)benzoyl]amino][1,1'-biphenyl]-4-yl]carbamic acid 1,1-dimethylethyl ester
• Carbamic acid, N-[3-[[4-(chloromethyl)benzoyl]amino][1,1'-biphenyl]-4-yl]-, 1,1-dimethylethyl ester

N-[3-[[4-(Chloromethyl)benzoyl]amino][1,1'-biphenyl]-4-yl]carbamic Acid tert-Butyl Ester

Controlled Product

CAS: 1003316-10-6

Applications N-[3-[[4-(Aminomethyl)benzoyl]amino][1,1'-biphenyl]-4-yl]carbamic Acid tert-Butyl Ester is a reactant used in the preparation of carboxybenzylamino biaryls as histone deacetylase inhibitors and in the optimization of biaryl selective HDAC1&2 inhibitors.
References Witter, D. et al.: Bioorg. Med. Chem. Lett., 18, 726 (2008)

Formula: C₂₅H₂₅ClN₂O₃

Color and Shape: Neat

Molecular weight: 436.93

Ref: TR-C369670