CAS 1003845-08-6: 2-Chloropyrimidine-5-boronic acid pinacol ester

Description: 2-Chloropyrimidine-5-boronic acid pinacol ester is an organoboron compound characterized by the presence of a pyrimidine ring substituted with a chlorine atom and a boronic acid moiety that is esterified with pinacol. This compound typically exhibits a white to off-white solid appearance and is soluble in organic solvents such as dichloromethane and ethanol, but may have limited solubility in water. The boronic acid functionality allows for participation in Suzuki-Miyaura cross-coupling reactions, making it valuable in organic synthesis, particularly in the formation of carbon-carbon bonds. The chlorine substituent on the pyrimidine ring can serve as a leaving group in nucleophilic substitution reactions. Additionally, the pinacol ester provides stability to the boronic acid group, enhancing its utility in various chemical transformations. Overall, this compound is significant in medicinal chemistry and materials science due to its reactivity and ability to form complex molecular architectures. Safety precautions should be observed when handling this compound, as with many organoboron derivatives, due to potential toxicity and reactivity.

Formula: C₁₀H₁₄BClN₂O₂

InChI: InChI=1S/C10H14BClN2O2/c1-9(2)10(3,4)16-11(15-9)7-5-13-8(12)14-6-7/h5-6H,1-4H3

Synonyms:

• 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine

2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine

CAS: 1003845-08-6

• Formula: C₁₀H₁₄BClN₂O₂
• Purity: >98.0%(GC)(T)
• Color and Shape: White to Yellow to Orange powder to crystal
• Molecular weight: 240.49

2-Chloropyrimidine-5-boronic acid pinacol ester, 98%

CAS: 1003845-08-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₁₀H₁₄BClN₂O₂
• Purity: 98%
• Molecular weight: 240.49

Pyrimidine, 2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

CAS: 1003845-08-6

• Formula: C₁₀H₁₄BClN₂O₂
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 240.4944

2-Chloropyrimidine-5-boronic acid, pinacol ester

CAS: 1003845-08-6

• Formula: C₁₀H₁₄BClN₂O₂
• Purity: 98+%
• Color and Shape: pale yellow solid
• Molecular weight: 240.49g/mol

2-Chloropyrimidine-5-boronic acid pinacol ester, 95%

CAS: 1003845-08-6

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₀H₁₄BClN₂O₂
• Purity: 95%
• Color and Shape: White to yellow to orange, Solid or crystalline solid
• Molecular weight: 240.49

2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine

CAS: 1003845-08-6

• Purity: 95.0%
• Color and Shape: Solid, Yellow powder
• Molecular weight: 240.49000549316406

2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine

CAS: 1003845-08-6

2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine is a pinacol ester that has been synthesized by the reaction of 2-aminopyrimidine-5-boronic acid …

• Formula: C₁₀H₁₄BClN₂O₂
• Purity: Min. 95%
• Molecular weight: 240.49 g/mol