CAS 1004-00-8

2-Amino-4-chlorothiophenol

Description:

2-Amino-4-chlorothiophenol, with the CAS number 1004-00-8, is an organic compound that features a thiophenol structure, characterized by the presence of a thiol (-SH) group and an amino (-NH2) group, along with a chlorine atom substituted on the aromatic ring. This compound typically appears as a solid and is known for its potential applications in the synthesis of dyes, pharmaceuticals, and agrochemicals. It exhibits properties such as moderate solubility in organic solvents and limited solubility in water, which is common for many thiophenol derivatives. The presence of both amino and chloro groups contributes to its reactivity, allowing it to participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. Additionally, 2-amino-4-chlorothiophenol may exhibit biological activity, making it of interest in medicinal chemistry. As with many chemical substances, proper handling and safety precautions are essential due to potential toxicity and environmental impact.

Formula: C₆H₆ClNS

InChI: InChI=1/C6H6ClNS/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,8H2

SMILES: c1cc(c(cc1Cl)N)S

Synonyms:

• Buttpark 35\10-17
• 2-Amino-4-Chlorobenzenethiol
• 4-Chloro-2-Aminothio-Phenol
• 2-Amino-4-Chloro Thoiphenol
• 2-Amino-4-Chloro Thiophenol
• 5-Chloro-2-mercaptoaniline
• 2-AMINO-4-CHLORO THIOPHENOL 97.0%MIN
• 2-AMINO-4-CHLOROTHIOPHENOL
• 4-Chloro-2-aminobenzenethiol
• 2-Amino-4-chlorothiophenol 96%

2-Amino-4-chlorobenzenethiol

CAS: 1004-00-8

Formula: C₆H₆ClNS

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow to Green powder to lump

Molecular weight: 159.63

Ref: 3B-A1625

2-Amino-4-chlorothiophenol, 96%

CAS: 1004-00-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₆ClNS

Purity: 96%

Color and Shape: Powder or fused solid, Pale cream to cream to yellow

Molecular weight: 159.63

Ref: 02-B25640

Benzenethiol, 2-amino-4-chloro-

CAS: 1004-00-8

Formula: C₆H₆ClNS

Purity: 95%

Color and Shape: Solid

Molecular weight: 159.6365

Ref: IN-DA0001WH

2-Amino-4-chlorothiophenol

CAS: 1004-00-8

2-Amino-4-chlorothiophenol

Formula: C₆H₆ClNS

Purity: 97%

Color and Shape: light yellow fused solid

Molecular weight: 159.64g/mol

Ref: 54-OR0785

2-Amino-4-chlorobenzenethiol

Controlled Product

CAS: 1004-00-8

Applications 2-Amino-4-chlorobenzenethiol is used as reagent in the synthesis of several organic compounds including that of MHY908 which is an inhibitor of melanogenesis and can potentially be used in the prevention and treatment of pigmentation disorders. Also used in the synthesis of γ-lactam analogs of prostaglandin E2 which may act as EP4 agonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Park, M., et al.: Arch. Pharm. Res., 38, 505 (2015); Kambe, T., et al.: Bioorgan. Med. Chem., 20, 3502 (2012);

Formula: C₆H₆ClNS

Purity: >85%

Color and Shape: Neat

Molecular weight: 159.64

Ref: TR-A604340

2-Amino-4-chlorobenzenethiol

CAS: 1004-00-8

Purity: 95%

Molecular weight: 159.63

Ref: 10-F791402