CAS 1004-40-6

6-amino-2-thiouracil hydrate

Description:

6-Amino-2-thiouracil hydrate is a chemical compound that belongs to the class of thiouracil derivatives, which are characterized by the presence of a thiol group (-SH) and an amino group (-NH2) on a pyrimidine ring. This compound is known for its potential biological activity, particularly in the context of its role as an antimetabolite, which can interfere with nucleic acid synthesis. The hydrate form indicates that it contains water molecules in its crystalline structure, which can influence its solubility and stability. 6-Amino-2-thiouracil is often studied for its pharmacological properties, including its effects on thyroid function and its potential use in treating certain medical conditions. The compound is typically a white to off-white solid and may exhibit moderate solubility in water, depending on the specific conditions. As with many thiouracil derivatives, it is important to handle this substance with care due to its biological activity and potential toxicity.

Formula: C₄H₅N₃OS

InChI: InChI=1S/C4H5N3OS/c5-2-1-3(8)7-4(9)6-2/h1H,(H4,5,6,7,8,9)

InChI key: InChIKey=YFYYRKDBDBILSD-UHFFFAOYSA-N

SMILES: NC1=CC(=O)NC(=S)N1

Synonyms:

• 2-Mercapto-4-amino-6-hydroxypyrimidine
• 2-Mercapto-6-aminouracil
• 2-Thio-4-amino-6-hydroxypyrimidine
• 2-Thio-6-aminouracil
• 4(1H)-pyrimidinone, 6-amino-2,3-dihydro-2-thioxo-
• 4(3H)-pyrimidinone, 6-amino-2-mercapto-
• 4-Amino-2-thiouracil
• 4-Amino-6-hydroxy-2-mercaptopyrimidine
• 4-Amino-6-hydroxy-2-sulfanylpyrimidine
• 4-Amino-6-hydroxy-2-thiopyrimidine
• 4-Hydroxy-6-amino-2-mercaptopyrimidine
• 4-Pyrimidinol, 6-Amino-2-Mercapto-
• 6-(aminosulfanyl)pyrimidine-2,4(1H,3H)-dione
• 6-Amino-2,3-dihydro-2-thioxo-4(1H)-pyrimidinone
• 6-Amino-2-mercapto-4(3H)-pyrimidinone
• 6-Amino-2-mercapto-4-pyrimidinol
• 6-Amino-2-mercapto-pyrimidin-4-ol
• 6-Amino-2-sulfanyl-4(3H)-pyrimidinone
• 6-Amino-2-sulfanylpyrimidin-4(3H)-one
• 6-Amino-2-sulfanylpyrimidin-4-ol
• 6-Amino-2-thiouracil
• 6-Amino-4-Hydroxy-2-Mercapto-Pyrimidine
• 6-Amino-4-hydroxy-2-mercaptopyrimidine
• 6-Amino-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine
• 6-Aminothiouracil
• 6-amino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
• 6-amino-2-thioxo-2,5-dihydropyrimidin-4(3H)-one
• Ab 48
• NSC 1587
• NSC 202018
• NSC 321193
• NSC 321194

4-Amino-6-hydroxy-2-mercaptopyrimidine

CAS: 1004-40-6

Formula: C₄H₅N₃OS

Purity: >98.0%(T)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 143.16

Ref: 3B-A0791

6-Amino-2,3-dihydro-2-thioxo-4(1H)-pyrimidinone

CAS: 1004-40-6

Formula: C₄H₅N₃OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 143.1670

Ref: IN-DA00389P

6-Amino-2-thiouracil

CAS: 1004-40-6

6-Amino-2-thiouracil

Formula: C₄H₅N₃OS

Purity: 98%

Color and Shape: white to off-white solid

Molecular weight: 143.17g/mol

Ref: 54-OR6128

6-Amino-4-hydroxy-2-mercaptopyrimidine

CAS: 1004-40-6

Formula: C₄H₅N₃OS

Purity: 95%

Color and Shape: Solid

Molecular weight: 143.16

Ref: 10-F077086

6-Amino-2-thiouracil-13C Monohydrate

Controlled Product

CAS: 1004-40-6, 1246816-15-8

Applications LAbelled derivative of 6-Amino-2-thiouracil as novel, potent, and selective A3 adenosine receptor antagonists.
References Ji, X., et al.: Drug Dev. Res., 33, 51 (1994), Poulsen, S., et al.: Bioorg. Med. Chem., 6, 619 (1998), Fredholm, B., et al.: Pharmacol. Rev., 53, 527 (2001), Gessi, S., et al.: Clin. Cancer Res., 10, 5895 (2004), Moro, S., et al.: Med. Chem. Res., 26, 131 (2006), Tafi, A., et al.: J. Med. Chem., 49, 4085 (2006),

Formula: C₃CH₅N₃OS·H₂O

Color and Shape: Neat

Molecular weight: 162.18

Ref: TR-A630457