CAS 1004-76-8

4,5-Diamino-6-hydroxy-2-mercaptopyrimidine

Description:

4,5-Diamino-6-hydroxy-2-mercaptopyrimidine, with the CAS number 1004-76-8, is an organic compound that belongs to the class of pyrimidines, which are heterocyclic aromatic organic compounds. This substance features a pyrimidine ring substituted with two amino groups at the 4 and 5 positions, a hydroxyl group at the 6 position, and a mercapto group at the 2 position. These functional groups contribute to its reactivity and potential applications in various fields, including pharmaceuticals and biochemistry. The presence of amino and mercapto groups suggests that it may participate in various chemical reactions, such as nucleophilic substitutions or redox reactions. Additionally, the hydroxyl group can engage in hydrogen bonding, influencing the compound's solubility and interaction with biological systems. Overall, 4,5-Diamino-6-hydroxy-2-mercaptopyrimidine is of interest for its potential roles in medicinal chemistry and as a building block in the synthesis of more complex molecules.

Formula: C₄H₆N₄OS

InChI: InChI=1S/C4H6N4OS/c5-1-2(6)7-4(10)8-3(1)9/h5H2,(H4,6,7,8,9,10)

InChI key: InChIKey=QYSWOQHLIDKEOL-UHFFFAOYSA-N

SMILES: NC1=C(N)NC(=S)NC1=O

Synonyms:

• 2-Mercapto-4,5-diamino-6-hydroxypyrimidine
• 2-Mercapto-4-hydroxy-5,6-diamino-pyrimidine
• 4(1H)-Pyrimidinone, 5,6-diamino-2,3-dihydro-2-thioxo-
• 4,5-Diamino-2-Mercaptopyrimidine-6-Ol
• 4,5-Diamino-2-mercaptopyrimidin-6-ol
• 4,5-Diamino-6-hydroxy-2-mercaptopyrimidine
• 4-5-Diamino-6-Hydroxy-2-*Mercaptopyrimidine Free
• 5,6-Diamino-2,3-dihydro-2-thioxo-4(1H)-pyrimidinone
• 5,6-Diamino-2-Mercaptopyrimidin-4-Ol
• 5,6-Diamino-2-mercapto-1H-pyrimidin-4-one
• 5,6-Diamino-2-mercapto-pyrimidin-4-ol
• 5,6-Diamino-2-thiouracil
• 5,6-Diamino-4-Hydroxy-2-Mercaptopyrimidine
• 5,6-diamino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
• NSC 147804
• NSC 45759

4(1H)-Pyrimidinone, 5,6-diamino-2,3-dihydro-2-thioxo-

CAS: 1004-76-8

Formula: C₄H₆N₄OS

Purity: 85%

Color and Shape: Solid

Molecular weight: 158.1816

Ref: IN-DA0001WN

5,6-Diamino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

CAS: 1004-76-8

5,6-Diamino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Purity: 97%

Molecular weight: 158.18g/mol

Ref: 54-OR95308

4,5-Diamino-6-hydroxy-2-mercapto pyrimidine

CAS: 1004-76-8

4,5-Diamino-6-hydroxy-2-mercaptopyrimidine is a primary amino that binds to the sulfur in a molecule. It has potent antibacterial activity and can be used for desulfurization of petroleum products. 4,5-Diamino-6-hydroxy-2-mercaptopyrimidine has been shown to react with some cancer cells in vitro and may be used as an anticancer agent. It can also be used as a catalyst for the oxidation of organic compounds in wastewater treatment or hydrochloric acid production. 4,5-Diamino-6-hydroxy-2-mercaptopyrimidine can be synthesized by reacting 3 mercapto propionic acid with 5 aminopyrimidines. The synthesis was optimized using a kinetic method and coordination chemistry. It has also been shown to inhibit cell growth when used on human erythrocytes using patch clamp experiments and assays.br>br

Formula: C₄H₆N₄OS

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 158.18 g/mol

Ref: 3D-FD21455

5,6-Diamino-2-thiouracil Hydrochloride Salt (80%)

Controlled Product

CAS: 1004-76-8

Applications Key intermediate in the production of anticancer and analgesic agents.
References Novellino, E., et al.: J. Med. Chem., 48, 8253 (2005), Chauhan, P., et al.: Bioorg. Med. Chem., 13, 3513 (2005), Lee, K., et al.: Eur. J. Med. Chem., 41, 1347 (2006),

Formula: C₄H₆N₄OS(xHCl)

Purity: 80%

Color and Shape: Neat

Molecular weight: 158.18 (free base)

Ref: TR-D416815

5,6-Diamino-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

CAS: 1004-76-8

Formula: C₄H₆N₄OS

Purity: 95%

Color and Shape: Solid

Molecular weight: 158.18

Ref: 10-F049441

5,6-Diamino-2-thiouracil-13C2,15N

Controlled Product

CAS: 1004-76-8

Formula: C₂C₂H₆₁₅NN₃OS

Color and Shape: Neat

Molecular weight: 161.16

Ref: TR-D416818