CAS 100481-09-2

2-Thiazolesulfonyl chloride

Description:

2-Thiazolesulfonyl chloride is a chemical compound characterized by its thiazole ring structure, which is a five-membered heterocyclic ring containing both sulfur and nitrogen atoms. This compound is typically a colorless to pale yellow liquid or solid, known for its reactivity due to the presence of the sulfonyl chloride functional group. It is commonly used as a sulfonylating agent in organic synthesis, facilitating the introduction of sulfonyl groups into various organic molecules. The compound is sensitive to moisture and can hydrolyze in the presence of water, releasing hydrochloric acid and forming the corresponding sulfonic acid. It is important to handle 2-thiazolesulfonyl chloride with care, as it can be corrosive and may cause irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment, are essential when working with this substance in a laboratory setting. Its applications extend to pharmaceuticals and agrochemicals, where it plays a role in the development of various bioactive compounds.

Formula: C₃H₂ClNO₂S₂

InChI: InChI=1/C3H2ClNO2S2/c4-9(6,7)3-5-1-2-8-3/h1-2H

SMILES: c1csc(n1)S(=O)(=O)Cl

Synonyms:

• 2-Thiazolesulfonylchloride(9CI)
• Thiazolesulfonyl chloride
• Thiazole-2-Sulfonyl Chloride
• 1,3-Thiazole-2-Sulfonyl Chloride

Thiazole-2-sulfonyl chloride

CAS: 100481-09-2

Formula: C₃H₂ClNO₂S₂

Purity: 90%

Color and Shape: Solid

Molecular weight: 183.6365

Ref: IN-DA00022V

2-Thiazolesulfonyl Chloride

Controlled Product

CAS: 100481-09-2

Applications Used for preparation of substituted thiazolesulfonamides as antiglaucoma agents.
References Boie, Y., et al.: Eur. J. Pharmacol., 340, 227 (1997), Boyer, F., et al.: J. Med. Chem., 43, 843 (2000), Lipinski, C., et al.: J. Pharmacol. Toxicol. Methods, 44, 235 (2000), Kimura, M., et al.: Endocrinology, 142, 4428 (2001),

Formula: C₃H₂ClNO₂S₂

Color and Shape: Yellow

Molecular weight: 183.64

Ref: TR-T344225