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CAS 10057-45-1

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7-(Trifluoromethyl)-1H-benzimidazol-2-amine

Description:
7-(Trifluoromethyl)-1H-benzimidazol-2-amine is a chemical compound characterized by its benzimidazole core, which is a bicyclic structure containing both benzene and imidazole rings. The presence of a trifluoromethyl group (-CF3) at the 7-position significantly influences its chemical properties, enhancing lipophilicity and potentially affecting its biological activity. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. It is of interest in medicinal chemistry due to its potential applications in pharmaceuticals, particularly as a scaffold for developing bioactive molecules. The trifluoromethyl group can also impart unique electronic properties, making it a valuable moiety in drug design. Additionally, the amine functional group at the 2-position can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. Overall, 7-(Trifluoromethyl)-1H-benzimidazol-2-amine is a versatile compound with significant implications in chemical research and development.
Formula:C8H6F3N3
InChI:InChI=1/C8H6F3N3/c9-8(10,11)4-2-1-3-5-6(4)14-7(12)13-5/h1-3H,(H3,12,13,14)
Synonyms:
  • 1H-benzimidazol-2-amine, 7-(trifluoromethyl)-
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